References
- Cariou B, Byrne CD, Loomba R, et al. Nonalcoholic fatty liver disease as a metabolic disease in humans: a literature review. Diab Obes Metab. 2021;23(5):1069–1083. doi: 10.1111/dom.14322
- Abenavoli L, Scarlata GGM, Scarpellini E, et al. Metabolic-Dysfunction-associated fatty liver disease and gut microbiota: from fatty liver to dysmetabolic syndrome. Med Kaunas Lith. 2023;59(3):594. doi: 10.3390/medicina59030594
- Definition & Facts of NAFLD & NASH - NIDDK [Internet]. Natl. Inst. Diabetes Dig. Kidney Dis. [cited 2023 Mar 12]. Available from: https://www.niddk.nih.gov/health-information/liver-disease/nafld-nash/definition-facts.
- Estes C, Razavi H, Loomba R, et al. Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease. Hepatology. 2018;67(1):123–133. doi: 10.1002/hep.29466
- Younossi ZM, Koenig AB, Abdelatif D, et al. Global epidemiology of nonalcoholic fatty liver disease—meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology. 2016;64(1):73–84. doi: 10.1002/hep.28431
- Powell EE, Wong V-S, Rinella M. Non-alcoholic fatty liver disease. Lancet Lond Engl. 2021;397(10290):2212–2224. doi: 10.1016/S0140-6736(20)32511-3
- Singal AG, Llovet JM, Yarchoan M, et al. AASLD practice guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma. Hepatology. 2023;78(6):1922–1965. doi: 10.1097/HEP.0000000000000466
- Younossi ZM, Blissett D, Blissett R, et al. The economic and clinical burden of nonalcoholic fatty liver disease in the United States and Europe. Hepatology. 2016;64(5):1577–1586. doi: 10.1002/hep.28785
- Younossi Z, Aggarwal P, Shrestha I, et al. The burden of non-alcoholic steatohepatitis: a systematic review of health-related quality of life and patient-reported outcomes. JHEP Rep Innov Hepatol. 2022;4(9):100525. doi: 10.1016/j.jhepr.2022.100525
- Huber Y, Boyle M, Hallsworth K, et al. Health-related quality of life in nonalcoholic fatty liver disease associates with hepatic inflammation. Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc. 2019;17(10):2085–2092.e1. doi: 10.1016/j.cgh.2018.12.016
- O’Hara J, Finnegan A, Dhillon H, et al. Cost of non-alcoholic steatohepatitis in Europe and the USA: the GAIN study. JHEP Rep Innov Hepatol. 2020;2(5):100142. doi: 10.1016/j.jhepr.2020.100142
- Vuppalanchi R, Noureddin M, Alkhouri N, et al. Therapeutic pipeline in nonalcoholic steatohepatitis. Nat Rev Gastroenterol Hepatol. 2021;18(6):373–392. doi: 10.1038/s41575-020-00408-y
- Brennan PN, Elsharkawy AM, Kendall TJ, et al. Antifibrotic therapy in nonalcoholic steatohepatitis: time for a human-centric approach. Nat Rev Gastroenterol Hepatol. 2023;20(10):679–688. doi: 10.1038/s41575-023-00796-x
- Rinella ME, Neuschwander-Tetri BA, Siddiqui MS, et al. AASLD practice guidance on the clinical assessment and management of nonalcoholic fatty liver disease. Hepatology. 2023;77(5):1797–1835. doi: 10.1097/HEP.0000000000000323
- Cusi K, Isaacs S, Barb D, et al. American association of clinical Endocrinology clinical practice guideline for the diagnosis and management of nonalcoholic fatty liver disease in primary care and Endocrinology clinical settings: co-sponsored by the American association for the study of liver Diseases (AASLD). Endocr Pract Off J Am Coll Endocrinol Am Assoc Clin Endocrinol. 2022;28:528–562.
- Porayko MK, Articolo A, Cerenzia W, et al. Differences in NAFLD/NASH management by provider specialty: opportunities for optimizing multidisciplinary care. J Multidiscip Healthc. 2022;15:1533–1545. doi: 10.2147/JMDH.S367607
- Shah AG, Lydecker A, Murray K, et al. Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc. 2009;7(10):1104–1112. doi: 10.1016/j.cgh.2009.05.033
- Scott SC, Goldberg MS, Mayo NE. Statistical assessment of ordinal outcomes in comparative studies. J Clin Epidemiol. 1997;50(1):45–55. doi: 10.1016/S0895-4356(96)00312-5
- Curcic IB, Berkovic MC, Kuna L, et al. Obesity paradox in chronic liver Diseases: product of bias or a real thing? J Clin Transl Hepatol. 2019;7(3):1–5. doi: 10.14218/JCTH.2019.00029
- Younossi ZM, Ong JP, Takahashi H, et al. A global survey of physicians knowledge about nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc. 2022;20(6):e1456–e1468. doi: 10.1016/j.cgh.2021.06.048
- Elsayed A, Ismaiel A, Procopio AC, et al. Noninvasive biochemical markers and surrogate scores in evaluating nonalcoholic steatohepatitis. Minerva Med. 2022;113(5):864–874. doi: 10.23736/S0026-4806.22.08185-X
- Novo Nordisk A/S. The effect of semaglutide in Subjects with Non-cirrhotic Non-alcoholic steatohepatitis [internet]. clinicaltrials.gov. 2023 [cited 2023 Apr 12]. Report No.: NCT04822181. Available from: https://clinicaltrials.gov/ct2/show/NCT04822181.
- Fullerton AS, Xu J. The proportional odds with partial proportionality constraints model for ordinal response variables. Soc Sci Res. 2012;41(1):182–198. doi: 10.1016/j.ssresearch.2011.09.003