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A synopsis of anti-psychotic medicinal plants in Nigeria

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References

  • Adelekan, M.L., MakanjuolA, A.B. & Ndom, R.J. 2001. Traditional mental health practitioners in Kwara State, Nigeria. East African Medical Journal 78: 190–196.
  • Adhikrao, V.Y. & Vandana S.N. 2008. Anti-dopaminergic effect of the methanolic extract of Morus alba L. leaves. Indian Journal of Pharmacology 40(5): 221–226. doi: 10.4103/0253-7613.44154
  • Agarwal, A., Deepika, B., Chanderpriya, A., Ratendra, K. & Veermaram, C. 2015. CNS stimulant and antidepressant activity of seeds of abelmoschus esculentus in rats. Bulletin of Pharmaceutical Research 5(2): 47–50.
  • Akinpelu, D.A. 2000. Anti-microbial activity of Bryophyllum pinnatum leaves. Fitoterapia 71(2): 193–194. doi: 10.1016/S0367-326X(99)00135-5
  • Akinpelu, D.A., Aiyegoro, O.A. & Okoh, A.I. 2008. In vitro antimicrobial and phytochemical properties of crude extract of stem bark of Afzelia Africana (Smith). African Journal of Biotechnology 7: 3665–3670.
  • Akpanabiatu, M.I., Umoh, I.B. & Eyong, E.U. 2006. Influence of Rauwolfia vomitoria root bark on cardiac enzymes on normal Wistar albino rats. Recent Progress in Medicinal Plants 14: 273–278.
  • Andretic, R., Kim, Y.C., Jones, F.S., Han, K.A. & Greenspan, R.J. 2008. Drosophila D1 dopamine receptor mediates caffeine-induced arousal. Proceedings of the National Academy of Sciences USA 105: 20392–20397. doi: 10.1073/pnas.0806776105
  • Arong, G.A., Oku, E.E., Obhiokhenan, A.A., Adetunji, B.A. & Mowang, D.A. 2011. PROTECTANT ability of Xylopia aethiopica and Piper guineense leaves against the Cowpea Bruchid Callosobruchus maculatus (Fab.) (Coleoptera: Bruchidae). World Journal of Science and Technology 1(7): 14–19.
  • Arowona, I.T., Sonibare, M.A. & Umukoro, S. 2014. Antipsychotic property of solvent-partitioned fractions of Lonchocarpus cyanescens leaf extract in mice. Journal of Basic Clinical Physiology and Pharmacology 25(2): 235–240. doi: 10.1515/jbcpp-2013-0065
  • Arya, V.S. 1997. Indian Medicinal Plants, Vol. 14. Chennai, Orient Longman Limited pp. 65–67.
  • Augusti, K.T. 1996. Therapeutic values of onion (Allium cepa L.) and garlic (Allium sativum L.). Indian Journal of Experimental Biology 34: 634–640.
  • Augustin, J.M., Kuzina, V., Andersen, S.B. & Bak, S. 2011 Molecular activities, biosynthesis and evolution of triterpenoid saponins. Phytochemistry 72: 435–457. doi: 10.1016/j.phytochem.2011.01.015
  • Ayoka, A.O., Rufus, O.A., Ezekiel, O.I., Moses, A.A. & Otas, E.U. 2006. Sedative, antiepileptic and antipsychotic effects of Spondias mombin L. (Anacardiaceae) in mice and rats. Journal of Ethnopharmacology 103:166–175. doi: 10.1016/j.jep.2005.07.019
  • Ayorinde, O., Gureje, O. & Lawal, R. 2004. Psychiatric research in Nigeria: bridging tradition and modernization. British Journal of Psychiatry 184:536–538. doi: 10.1192/bjp.184.6.536
  • Azeem, S.W., Khan, M.A. & Ahmad, I. 2005. Characterisation of oxidation products of Rauwolfia alkaloids. Pakistan Journal of Pharmaceutical Science 18(1): 33–35.
  • Baldé, A.M., Traoré, M.S., Diallo, M.S.T., Baldé, E.S., Huang, Y., Liu, Z., Oularé, K., Barry, M.S., Baldé, M.A., Camara, A., Berghe, V.D., Vlietinck, A. & Pieters, L. 2015. Ethnobotanical survey, antimicrobial and anti-complement activities of Guinean medicinal plants traditionally used in the treatment of inflammatory diseases in Conakry and Dubreka. Journal of Plant Sciences 3: 11–19.
  • Bandaranayake, W.M. 2006. Quality control, screening, toxicity, and regulation of herbal drugs. In Ahmad, I., Aqil, F. & Owais M. (Eds), Modern Phytomedicine. Turning Medicinal Plants into Drugs. Weinheim, Wiley, pp. 25–57.
  • Biney, R.P., Mante, P.K., Boakye-Gyasi, E. & Woode, E. 2014. Neuropharmacological effects of an ethanolic fruit extract of Xylopia aethiopica and xylopic acid, a kaurene diterpene isolate, in mice. West African Journal of Pharmacy 25(1): 106–117.
  • Bisong, S., Brown, R. & Osim, E. 2011. Comparative effects of Rauwolfia vomitoria and chlorpromazine on social behaviour and pain. North American Journal of Medical Sciences 3(1):48–54. doi: 10.4297/najms.2011.348
  • Burkill, H.M. 1985. The Useful Plants of West Tropical Africa, 2nd edn. Kew, Royal Botanic Gardens.
  • Chopra, R.N., Nayor, S.L. & Chopra, I.C. 1996. Glossary of Indian Medical Plants. Clinical Chemistry 50: 400–450.
  • Chung, I.W., Won, K., Yong, S.K., Joo, B.P., Jong, S.A., Hyun, S.L., Woon, T.K. & Chang, I.L. 2000. The effect of polygalasaponins in Polygalae Tenuifolia on apomorphine-induced hyperlocomotions in mice. The Korean Journal of Psychopharmacology 11: 3.
  • Chung, I.W., Moore, N.A., Oh, W.K., O'neill, M.F., Ahn, J.S., Park, J.B., Kang, U.G. & Kim, Y.S. 2002. Behavioural pharmacology of polygalasaponins indicates potential antipsychotic efficacy. Pharmacology Biochemistry and Behavior 71(1–2): 191–195. doi: 10.1016/S0091-3057(01)00648-7
  • Costa, S., Jossang, A. & Bodo, B 1995. Propietes biologiques et phytochiie des kalanchoe pinnata. In Boiteau, P. & Allorge-Boiteau L. (Eds), Kalanchoe des Madagacar. Systematique, ecophysiologie et phytochimie. Paris, Karthala, pp. 219–235.
  • Curb, J.D., Schneider, K., Taylor, J.O., Maxwell, M. & Shulman, N. 1988. Antihypertensive drug side effects in the Hypertension Detection and Follow-up Program. Hypertension 113(2): 1151–1155.
  • Dalziel, J.M. 1936. The Useful Plants of West Tropical Africa. Watmonghs, Idle, London, pp. 354–355.
  • Dhawan, K., Dhawan, S. & Sharma, A. 2004. Passiflora: a review update. Journal of Ethnopharmacology 94: 1–23. doi: 10.1016/j.jep.2004.02.023
  • Ebbo, A.A., Elsa, A. T., Etuk, E.U., Ladan, M.J. & Saganuwan, S.A. 2008. Antipsychotic effect of aqueous stem bark extract of Amblygonocarpus andongensis in wistar albino rats. Animal Research International 5(2): 831–834.
  • Enwezor, W.O., Ohiri, A.C. & Opuwaribo, E.E. 1988. A review of fertilizer use on crops in southeastern zone of Nigeria. Rural Development 1: 53–100.
  • Fakeye, T.O., Itiola, O.A. & Odelila, H.A. 2000. Evaluation of the antimicrobial property of stem bark of Picralima nitida (Apocynaceae). Phytotheraphy Research 14: 386–390. doi: 10.1002/1099-1573(200008)14:5<368::AID-PTR615>3.0.CO;2-X
  • Falade, M.O., Akinboye, D.O., Gbotosho, G.O., Ajaiyeoba, E.O., Happi, T.C., Abiodun, O.O. & Oduola, A.M.J. 2014. In vitro and in vivo antimalarial activity of Ficus thonningii Blume (Moraceae) and Lophira alata Banks (Ochnaceae), identified from the Ethnomedicine of the Nigerian Middle Belt. Journal of Parasitology Research doi: 10.1155/2014/972853.
  • Farombi, E.O. 2003. African indigenous plants with chemotherapeutic potentials. A mythological approach to the production of bioactive prophylacticagent. African Journal of Biotechnology 2(12): 662–671. doi: 10.5897/AJB2003.000-1122
  • Gbile, Z.O. 1984. Vernacular Names of Nigerian Plants. Ibadan, Forest Research Institute of Nigeria.
  • Gill, S. 1992. Ethno-medical Uses of Plants in Nigeria. Benin, Uniben Press.
  • Gritsai, O.B., Dubynin, V.A., Pilipenko, V.E. & Petrov, O.P. 2004. Effects of peptide and non-peptide opioids on protective reaction of the cockroach Periplaneta americana in the "hot camera". Journal of Evolutionary Biochemistry and Physiology 40: 153–160 doi: 10.1023/B:JOEY.0000033806.85565.3e
  • Gupta, S., Vinay, K.K., Anupam, M., Dnyaneshwar, U.B., Rajendra, K.S., Anirban, P. & Santosh, K.S 2012. Bioactivity guided isolation of antipsychotic constituents from the leaves of Rauwolfia tetraphylla L. Fitoterapia 83(6): 1092–1099. doi: 10.1016/j.fitote.2012.04.029
  • Herrmann, AP., Lunardi, P., Pilz, L.K., Tramontina, A.C., Linck, V.M., Okuryi, C.O., Gonçalves, C.A. & Elisabetsky, E., 2012. Effects of the putative antipsychotic alstonine on glutamate uptake in acute hippocampal slices. Neurochemistry International 61(7): 1144–1150. doi: 10.1016/j.neuint.2012.08.006
  • Hu, P.F., Fan, R.P., Li, Y.P. & Pang, C.Y. 2001. Studies on pharmacological action of Luohuashengzhiye extract. Chinese Traditional Patent Medicine 23: 919–920.
  • Ibrahim, J.A., Muazzam, I., Jegede, I.A., Kunle, O.F. & Okogun, J.I. 2007. Ethno-medicinal plants and methods used by Gwandara tribe of Sabo Wuse in Niger State, Nigeria, to treat mental illness. African Journal of Traditional, Complementary and Alternative Medicines. 2: 211–218.
  • Iviane, M., Linck, A.P. & Herrmann, Â.L.P. 2011. Alstonine as an antipsychotic: effects on brain amines and metabolic changes. Evidence-Based Complementary and Alternative Medicine. Article ID 418597, 7 pages. doi:10.1093/ecam/nep002.
  • Jin, Z., Nana, G., Xiao-Rong, L., Yu, T., Jie, X., Hong-Xia, C., Rui, X. & Yun-Feng, L. 2015. The antidepressant-like pharmacological profile of yuanzhi-1, a novel serotonin, norepinephrine and dopamine reuptake inhibitor. European Journal of Neuropsychopharmacology 25(4): 544–556. doi: 10.1016/j.euroneuro.2015.01.005
  • Joel, E. H., Lee, E.L., Perry, B.M., Raymond, W.R. & Alfred, G. G. 1996. Amphetamine In Goodman and Gilman (Eds), The Pharmacological Basis of Therapeutics, 9th edn. pp. 219–221.
  • Kabir, M., Iliyasu, Z., Abubakar I.S. & Aliyu, M.H. 2004. Perception and beliefs about mental illness among adults in Karfi village, Northern Nigeria. BMC International Health and Human Rights 4: 3. doi: 10.1186/1472-698X-4-3
  • Kadian, R. & Parle, M. 2014. Evaluation of anti-psychotic effect of Allium cepa. World Journal of Pharmacy and Pharmaceutical Sciences 3: 1146–1159.
  • Keay, R.W.J., Onochie, C.F.A. & Stanfield, D.P. 1964. Nigerian Trees, Vol. 1. Department of Forest Research.
  • Kennedy, D.O. & Wightman, E.L. 2011. Herbal extracts and phytochemicals: plant secondary metabolites and the enhancement of human brain function. Advances in Nutrition 2: 32–50. doi: 10.3945/an.110.000117
  • Khanra, S., Khess C.R.J. & Srivastava, N. 2015. Chronic non-fatal Datura abuse in a patient of schizophrenia: a case report. Addictive Behaviors 43: 39–41. doi: 10.1016/j.addbeh.2014.12.002
  • Khomsug, P., Thongiaroenbuangan, W., Pakdeenarong, N., Suttajit, M. & Chantitratikul, P. 2010. Antioxidative activities and phenolic content of extracts from okra (Abelmoschus esculentus). Russian Journal of Biological Science 5: 310–13. doi: 10.3923/rjbsci.2010.310.313
  • Kim, D.H., Jeon, S.J., Son, K.H., Jung, J.W., Lee, S. Yoon, B.H., Lee, J.J., Cho, Y.W. & Cheong, J.H. 2007. The ameliorating effect of oroxylin A on scopolamine-induced memory impairment in mice. Neurobiology of Learning and Memory 87: 536–546. doi: 10.1016/j.nlm.2006.11.005
  • Kochanowska-Karamyan, A.J. & Mark, T.H. 2010. Marine indole alkaloids: potential new drug leads for the control of depression and anxiety. Chemical Reviews 110(8): 4489–4497. doi: 10.1021/cr900211p
  • Lieberman, J.A., Stroup, T.S., McEvoy, J.P., Swartz, M.S., Rosenheck, R.A. & Perkins, D.O. 2005. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. New England Journal of Medicine 353(12): 1209–1223. doi: 10.1056/NEJMoa051688
  • Linck, V.M., Herrmann. A.P., Piato, A.L., et al. 2011. Alstonine as an antipsychotic: effects on brain amines and metabolic changes. Evidence-based Complementary and Alternative Medicine 2011: 418597. doi:10.1093/ecam/nep002.
  • Loretta, O.I., Mohammed, G.M. & Ogbonnaya, N. 2015. Evaluation of antipsychotic properties of aqueous extract of Lophira alata (Ochnaceae) and Afzelia africana (Leguminosae) stem barks in rats. Nigerian Journal of Pharmaceutical and Applied Science Research 4(3): 19–25.
  • Lozano, V.C., Armengaud, C. & Gauthier, M. 2001 Memory impairment induced by cholinergic antagonists injected into the mushroom bodies of the honeybee. Journal of Comparative Physiology 187: 249–254. doi: 10.1007/s003590100196
  • Machado, D.G., Neis, V.B., Balen, G.O., Colla, A. Cunha, M.B., Pizzolatti, M.J. Prediger, R.D. & Rodrigues, A.L.S. 2012. Antidepressant-like effect of ursolic acid isolated from Rosmarinus officinalis L. in mice: evidence for the involvement of the dopaminergic system. Pharmacology Biochemistry and Behavior 103(2): 204–211. doi: 10.1016/j.pbb.2012.08.016
  • Magaji, M.G., Anuka, J.A., Abdu-Aguye, I., Yaro, A.H. & Hussaini, I.M. 2008. Behavioural effects of the methanolic root bark extract of Securinega virosa in rodents. African Journal of Traditional Complementary and Alternative Medicines,. 5: 147–153. doi: 10.4314/ajtcam.v5i2.31266
  • Magaji, M.G., Yakubu, Y., Magaji, R.A., Musa, A.M., Yaro, A.H. & Hussaini, I.M. 2013. Psychopharmacological potentials of methanol leaf extracts of Securiniga virosa Roxb(Ex Willd) Baill in mice. Pakistan Journal of Biological Sciences 1–5.
  • Magassouba, F.B., Diallra, A., Camara, A., Keita, S., Barry, M.S., Donzo, M., Bangoura, O. & Pieters, L. 2007. Ethnobotanical survey and antibacterial activity of some plants used in Guinea traditional medicine. Journal of Ethnopharmacology 114: 44–53. doi: 10.1016/j.jep.2007.07.009
  • Mathivanan, N., Surendiran, G., Srinivasan, K., Sagadevan, E. & Malarvizhi, K. 2005 Review on the current scenario of Noni research: taxonomy, distribution, chemistry, medicinal and therapeutic values of Morinda citrifolia. International Journal of Noni Research 1(1): 1–16.
  • Medical Cannabis News and Information. 2013. Cannabinoids chronicle 6(8). Accessed 17 October 2016.
  • Mhaskar, K.S., Latter, E.B. & Caius, J.S. 2000. Kirtikar and Basu's Indian Medicinal Plants, Vol. 3. Sri Satguru Publications: New Delhi.
  • Moses, T., Pollier, J., Thevelein, J.M. & Goossens, A. 2013. Bioengineering of plant (tri) terpenoids: from metabolic engineering of plants to synthetic biology in vivo and in vitro. New Phytologist 200: 27–43. doi: 10.1111/nph.12325
  • Muzitano, M.F., Luzineide, W.T. Catherine, G., Kaiser, C.R., Rossbergmann, B. & Costa, S.S. 2006. The antileishmanial activity assessment of unusual flavonoids from Kalanchoe pinnata. Phytochemistry 67: 2071–2077. doi: 10.1016/j.phytochem.2006.06.027
  • Myin-Germeys, I., Vanos, J., Schwartz, J.E., Stone, A.A. & Delespaul, P.A. 2001. Emotional reactivity to daily life stress in psychosis. Archives of General Psychiatry 58: 1137–1144. doi: 10.1001/archpsyc.58.12.1137
  • Neuwinger, J.D. 1996. Translated from by Porter A. African ethnobotany poison and drugs. Weinheim, Chapman and Hall, pp. 495–499.
  • Obembe, A., Sokomba, E.N., Sijuwola, O.A., Olorunfemi, P.O., Alemika, T.O., Isichei, C.O., Ogunkeye, O.O. & Bangudu, A.B. 1994. Antipsychotic effects and tolerance of crude Rauvolfia vomitoria in Nigerian psychiatric inpatients Phytotherapy Research doi: 10.1002/ptr.2650080406.
  • Odugbemi, T. 2008. A Textbook of Medicinal Plants from Nigeria. Lagos, University of Lagos Press.
  • Ojewole, J.A.O. 2002. Antihypertensive properties of Bryophyllum pinnatum leaf extracts. American Journal of Hypertension 15(4): 34–39. doi: 10.1016/S0895-7061(02)02353-1
  • Okwute, S.K. 1992. Plant derived pesticidal and antimicrobial agents for use in agriculture. A review of phytochemical and biological studies on some Nigerian plants. Journal of Agricultural Science and Technology 2(1): 62–70.
  • Olonisakin, A., Oladimeji, M.O. & Lajide, L. 2006. Chemical composition and antibacterial activity of steam distilled oil of Ashanti pepper (Piper guineense) fruits (Berries). Electron. Journal of Environmental, Agricultural and Food Chemistry 5(5): 1531–1535.
  • Orwa, C., Mutua, A., Kindt, R., Jamnadass, R. & Simons, A. 2009. Agrofores tree database: A tree reference and selection guide. version 4. http://www.worldagroforestry.org/af/treedb/ (accessed 12 September 2015).
  • Oyemitan, I.A., Olayera, O.A., Alabi, A., Abass, L.A., Elusiyan, C.A., Oyedeji, A.O. & Akanmu, M.A. 2015. Psychoneuropharmacological activities and chemical composition of essential oil of fresh fruits of Piper guineense (Piperaceae) in mice. Journal of Ethnopharmacology 166: 240–249. doi: 10.1016/j.jep.2015.03.004
  • Pal, S., Sen, T. & Nag, A.K. 1999. Neuropsychopharmacological profile of the methanolic fraction of Bryophyllum Pinnatum leaf extract. Journal of Pharmacy and Pharmacology 51: 313–318. doi: 10.1211/0022357991772312
  • Pandy, V., Megala, N. & Zahurin, M. 2012. Antipsychotic-like activity of Noni (Morinda citrifolia Linn.) in mice. International Society for Complementary Medicine Research doi: 10.1186/1472-6882-12-186.
  • Pattanayak, P., Behera, P., Das, D. & Panda, S.K. 2010. Ocimum sanctum Linn. A reservoir plant for therapeutic applications: an overview. Pharmacognosy Reviews 4(7): 95–105. doi: 10.4103/0973-7847.65323
  • Perry, N., Court, G., Bidet, N., Court, J. & Perry, E. 1996. European herbs with cholinergic activities: potential in dementia therapy. International Journal of Geriatric Psychiatry 11: 1063–1069. doi: 10.1002/(SICI)1099-1166(199612)11:12<1063::AID-GPS532>3.0.CO;2-1
  • Ralston, L., Subramanian, S., Matsuno, M. & Yu, O. 2005 Partial reconstruction of flavonoid and isoflavonoid biosynthesis in yeast using soybean type I and type II chalcone isomerases. Plant Physiology 137: 1375–1388. doi: 10.1104/pp.104.054502
  • Rattan, R.S 2010. Mechanism of action of insecticidal secondary metabolites of plant origin. Crop Protection 29: 913–920. doi: 10.1016/j.cropro.2010.05.008
  • Salahdeen, H.M. & Yemitan, O.K. 2006. Neuropharmacological Effects of Aqueous Leaf Extract of Bryophyllum Pinnatum in Mice. African Journal of Biomedical Research 9: 101–107.
  • Schultz, J.C. 2002. Shared signals and the potential for phylogenetic espionage between plants and animals. Integrative and Comparative Biology 42: 454–462. doi: 10.1093/icb/42.3.454
  • Sharma K., Milind, P. & Monu, Y. 2016. Evaluation of antipsychotic effect of methanolic extract of Ocimum sanctum leaves on laboratory animals. Journal of Applied Pharmaceutical Science 6(5): 171–177. doi: 10.7324/JAPS.2016.60527
  • Shuji, I. 2013. What happens in the brain of schizophrenia patients?: an investigation from the viewpoint of neuropathology. Nagoya Journal of Medical Science 75: 11–28.
  • Soni, P., Siddiqui, A.A., Dwivedi, J. & Soni, V. 2012. Pharmacological properties of Datura stramonium L. as a potential medicinal tree: An overview. Asian Pacific Journal of Tropical Biomedicine 2(12): 1002–1008. doi: 10.1016/S2221-1691(13)60014-3
  • Sonibare, M.A., Umukoro, S. & Shonibare, E.T. 2011. Antipsychotic property of aqueous and ethanolic extracts of Lonchocarpus cyanescens (Schumach and Thonn.) Benth. (Fabaceae) in rodents. Journal of Natural Medicine 66(1): 127–132. doi: 10.1007/s11418-011-0562-6
  • Stajner, D. & Varga, I.S., 2003. An evaluation of the antioxidant abilities of Allium species. Acta Biologica Szegediensis, 47: 103–106.
  • Tan, J., Galligan, J.J. & Hollingworth, R.M. 2007. Agonist actions of neonicotinoids on nicotinic acetylcholine receptors expressed by cockroach neurons. Neurotoxicology 28: 829–842. doi: 10.1016/j.neuro.2007.04.002
  • Tittel, G., Wagner, H. & Bos, R. 1982. Chemical composition of the essential oil from melissa. Planta Medica 46: 91–98. doi: 10.1055/s-2007-970028
  • Uchendu, C.N., Isek, T. 2008. Antifertility activity of aqueous ethanolic leaf extract of Spondias mombin (Anacardiaceae) in rats. African Health Sciences 8(3): 163–167.
  • Umukoro, S. 2016. Review of the challenges facing management of patients with psychotic disorder and the need for mental health policies in Nigeria. British Journal of Education, Society & Behavioural Science 12(1): 1–10. doi: 10.9734/BJESBS/2016/20144
  • van den Beukel, I., van Kleef, R. & Oortgiesen, M. 1998. Differential effects of physostigmine and organophosphates on nicotinic receptors in neuronal cells of different species. Neurotoxicology 19: 777–787.
  • Wang, Y.F., Li, H.F., Xu, Y.F., Zhang, Y.L., Xu, D.S., Xiao, L.M. & Li, XM. 2001a. Clinical confirmation of preparation from the branch and leaf of peanut in treating insomnia. Shanghai Journal of Traditional Chinese Medicine 62: 8–10.
  • Wang, Y.F., Li, H.F., Xu, Y.F., Zhang, Y.L., Xu, D.S., Xiao, L.M. & Li XM. 2001b. Clinical confirmation of preparation from the branch and leaf of peanut in treating insomnia. Shanghai Journal of Traditional Chinese Medicine 62: 8–10.
  • WHO, 2004. WHO Guidelines on Safety Monitoring of Herbal Medicines in Pharmacovigilance Systems. Geneva, World Health Organization.
  • Wink, M. 2000. Interference of alkaloids with neuroreceptors and ion channels. Studies in Natural Products Chemistry 21: 3–122. doi: 10.1016/S1572-5995(00)80004-6
  • Woode, E, Robert, P.B., Priscilla, K.M., Eric, B. & Kennedy, E.K. 2014. Neuropharmacological effects of an ethanolic fruit extract of Xylopia aethiopica and xylopic acid, a kaurene diterpene isolate, in mice. West African Journal of Pharmacy 25(1): 106–117.
  • Xu, Y., Wang, Z., You, W., Zhang, X., Li, S., Barish, P., Vernon, M., Du, X. & Li, G. 2010. Antidepressant-like effect of trans-resveratrol: involvement of se- rotonin and noradrenaline system. European Journal of Neuropsychopharmacology 20: 405–413. doi: 10.1016/j.euroneuro.2010.02.013
  • Zenk, M.H. & Juenger, M. 2007. Evolution and current status of the phytochemistry of nitrogenous compounds. Phytochemistry 68: 2757–2772. doi: 10.1016/j.phytochem.2007.07.009
  • Zhang, Z.J. 2004. Therapeutic effects of herbal extracts and constituents in animal models of psychiatric disorders. Life Science 75: 1659–1699. doi: 10.1016/j.lfs.2004.04.014
  • Zu, X., Zhang, Z., Xiong, G., Liao, A.O., Yiting, L.I., Shengrong, G. & Xin L.I. 2013. Sedative effects of Arachis hypogaea L. stem and leaf extracts on sleep-deprived rats. Experimental and Therapeutic Medicine. 6(2): 601–605. doi: 10.3892/etm.2013.1182
  • Zu, X.Y., Zhang, Z.Y., Liu, J.Q., Hu, H.H., Xing, G.Q., Zhang, Y. & Guan, D. 2010. Sedative effects of peanut (Arachis hypogaea L.) leaf aqueous extracts on brain ATP, AMP, adenosine and glutamate/GABA of rats. Journal of Biomedical Science and Engineering 3: 268–273. doi: 10.4236/jbise.2010.33036

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