References
- Ashrafian, H., Frenneaux, M.P. & Opie, L.H. 2007. Metabolic mechanisms in heart failure. Circulation 116: 434–448. doi: 10.1161/CIRCULATIONAHA.107.702795
- Befroy, D.E., Petersen, K.F., Dufour, S., Mason, G.F., de Graaf, R.A., Rothman, D.L. & Shulman G.I. 2007. Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients. Diabetes 56: 1376–1381. doi: 10.2337/db06-0783
- Boehme, D.H., Sobel, H.J., Marquet, E., Salen, G. 1980. Liver in Cerebrotendinous xanthomatosis (CTX). A histochemical and EM study of four cases. Pathology – Research and Practice 170: 192–201. doi: 10.1016/S0344-0338(80)80166-X
- Brehm, A., Krssak, M., Schmid, A.L., Nowotny, P., Waldhausl, W. & Roden, M. 2006. Increased lipid availability impairs insulin-stimulated ATP synthesis in human skeletal muscle. Diabetes 55: 136–140. doi: 10.2337/diabetes.55.01.06.db05-1286
- Bruce, C.R., Thrush, A.B., Mertz, V.A., Bezaire, V., Chabowski, A., Heigenhauser, G.J. & Dyc, D.J. 2006. Endurance training in obese humans imroves glucose intolerance, mitochondrial fatty oxidation and alters muscle lipid content. American Journal of Physiology – Endocrinology and Metabolism 291: E99. doi: 10.1152/ajpendo.00587.2005
- Eva, R.C. 2005. Role of CAMKII in skeletal muscle plasticity. Journal of Applied Physiology 99: 414–423. doi: 10.1152/japplphysiol.00015.2005
- Goodpaster, B.H, Theriault, R., Watkins, S.C. & Kelley, D.E. 2000. Intramuscular lipid content is increased in obesity and decreased by weight loss. Metabolism 49: 467–472. doi: 10.1016/S0026-0495(00)80010-4
- Greenberg, A.S., Coleman, R.A. & Kraemer, F.B. 2011. The role of lipid droplets in metabolic disease in rodents and humans. Journal of Clinical Investigation 121(6): 2102–2110. doi: 10.1172/JCI46069
- Hoelz, A., Nairn, A.C. & Kuriyan, J. 2003. Crystal structure of a tetradecameric assembly of the association domain of Ca2+/calmodulin-dependent kinase II. Molecular Cell 11(5): 1241–1251. doi: 10.1016/S1097-2765(03)00171-0
- Holloszy, J.O. 2004. Adaptations of skeletal muscle mitochondria to endurance exercise: a personal perspective. Exercise and Sport Sciences – Reviews 32: 41–43. doi: 10.1097/00003677-200404000-00001
- Hudmon, A. & Schulman, H. 2002. Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II. Biochemical Journal 364: 593–611. doi: 10.1042/bj20020228
- Joseph, J.S., Ayeleso, A.O. & Mukwevho, E. 2017. Exercise increases hyper-acetylation of histones on the cis-element of NRF-1 binding to the Mef2a promoter: Implications on type 2 diabetes. Biochemical and Biophysical Research Communications pii: S0006-291X(17)30441-2.
- Kim, H.J., Jung, T.W., Kang, E.S., Kim, D.J., Ahn, C.W., Lee, K.W., Lee, H.C. & Cha, B.S. 2007. Depot-specific regulation of perilipin by rosiglitazone in a diabetic animal model. Metabolism 56(5): 676–685. doi: 10.1016/j.metabol.2006.12.017
- Krssak, M., Falk Petersen, K., Dresner, A., Dipietro, L., Vogel, S.M., Rothman, D.L., Roden, M. & Shulman, G.I. 1999. Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia 42: 113–116. doi: 10.1007/s001250051123
- Lee, S.J., Zhang, J., Choi, A.M.K. & Kim, H.P. 2013. Mitochondrial dysfunction induces formation of lipid droplets as a generalized response to stress. Oxidative Medicine and Cellular Longevity 2013, 327167.
- Meex, R.C.R, Schrauwen, P. & Hesselink, M.K.C. 2009. Modulation of myocellular fat stores: lipid droplet dynamics in health and disease. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 297(4): R913–924. doi: 10.1152/ajpregu.91053.2008
- Mogensen, M., Sahlin, K., Fernstrom, M., Glintborg, D., Vind, B.F., Beck-Nielsen, H. & Hojlund, K. 2007. Mitochondrial respiration is decreased in skeletal muscle of patients with type 2 diabetes. Diabetes 56: 1592–1599. doi: 10.2337/db06-0981
- Mukwevho, E. & Joseph, J.S. 2014. Calmodulin dependent protein kinase II activation by exercise regulates saturated & unsaturated fatty acids and improves some metabolic syndrome markers. Life Science 111: 53–61. doi: 10.1016/j.lfs.2014.07.013
- Nisoli, E., Clementi, E., Carruba, M.O. & Moncada, S. 2007. Defective mitochondrial biogenesis: a hallmark of the high cardiovascular risk in the metabolic syndrome? Circulation Research 100: 795–806. doi: 10.1161/01.RES.0000259591.97107.6c
- Olofsson, S.O., BoströM, P., Andersson, L., Rutberg, M., Perman, J. & BoréN, J. 2009a. Lipid droplets as dynamic organelles connecting storage and efflux of lipids. Biochimica et Biophysica Acta 1791(6): 448–458. doi: 10.1016/j.bbalip.2008.08.001
- Olofsson, S.O., BoströM, P., Andersson, L., Li, L., Højlund, K., Adiels, M., Perkins, R. & Jan BoréN, J. 2009b. Lipid droplets and their role in the development of insulin resistance and diabetic dyslipidemia. Clinical Lipidology 4(5): 611–622. doi: 10.2217/clp.09.54
- Stump, C.S., Short, K.R., Bigelow, M.L., Schimke. J.M. & Nair, K.S. 2003. Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts. Proceedings of the National Academy of Sciences USA 100: 7996–8001. doi: 10.1073/pnas.1332551100
- Szendroedi, J., Schmid, A.I., Chmelik, M., Toth, C., Brehm, A., Krssak, M., Nowotny, P., Wolzt, M., Waldhausl, W. & Roden, M. 2007. Muscle mitochondrial ATP synthesis and glucose transport/phosphorylation in type 2 diabetes. PLoS Medicine 4: e154. doi: 10.1371/journal.pmed.0040154
- Toledo, F.G., Menshikova, E.V., Ritov, V.B., Azuma, K., Radikova, Z., Delany, J. & Kelley, D.E. 2007. Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes. Diabetes 56: 2142–2147. doi: 10.2337/db07-0141
- Wiederkehr, A. & Wollheim, C.B. 2006. Minireview: implication of mitochondria in insulin secretion and action. Endocrinology 147: 2643–2649. doi: 10.1210/en.2006-0057