53
Views
8
CrossRef citations to date
0
Altmetric
Article

A paracetamol‐pasta test for assessing gastric emptying in healthy and diabetic subjects

, , , , &
Pages 159-166 | Received 01 Jul 2002, Accepted 24 Feb 2003, Published online: 08 Jul 2009

REFERENCES

  • Horowitz M, Fraser R. Disordered gastric motor function in diabetes mellitus. Diabetologia 1994; 37: 543–51.
  • Lyrends EB, Olsson EHK, Arvidsson UC, Om TJ, Spjuth JH. Prevalence and determinants of solid and liquid gastric emptying in unstable type I diabetes. Diabetes Care 1997; 20: 413–18.
  • Keshavarzian A, Iber FL, Vaeth J. Gastric emptying in patients with insulin-requiring diabetes mellitus. Am J Gastroenterol 1987; 82: 29–35.
  • Jones KL, Horowitz M, Wishart JM, Maddox AF, Harding PE, Chatterton BE. Relationships between gastric emptying intragastric meal dis-tribution and blood glucose concentrations in diabetes mellitus. J Nucl Med 1995; 36: 2220–8.
  • Ishii M, Nakamura T, Kasai F, Onuma T, Baba T, Takebe K. Altered postprandial insulin require-ment in IDDM patients with gastroparesis. Diabetes Care 1994; 17: 901–3.
  • Kong M, Horowitz M. Gastric emptying in diabetes melllitus: relationship to blood-glucose control. Clin Geriatr Med 1999; 15: 321–38.
  • Rayner CK, Samsom M, Jones KL, Horowitz M. Relationships of upper gastrointestinal motor and sensory function with glycemic control. Diabetes Care 2001; 24: 371–81.
  • Hebbard GS, Samsom M, Sun WM, Dent J, Horowitz M. Hyperglycemia affects proximal gastric motor and sensory function during small intestinal triglyceride infusion. Am J Physiol 1996; 271: 814–9.
  • Schvarcz E, Palmer M, Aman J, Horowitz M, Stridsberg M, Berne C. Physiological hyperglyce-mia slows gastric emptying in normal subjects and patients with insulin-dependent diabetes mellitus. Gastroenterology 1997; 113: 60–6.
  • Schvarcz E, Palmer M, Aman J, Berne C. Hypoglycaemia increases the gastric emptying rate in healthy subjects. Diabetes Care 1995; 18: 674–6.
  • Schvarcz E, Palmer M, Aman J, Lindkvist B, Beckman K-W. Hypoglycaemia increases the gastric emptying rate in patients with type I diabetes mellitus. Diabet Med 1993; 10: 660–3.
  • Lartigue S, Bizais Y, Bruley Des Varannes S, Murat A, Pouliquen B, Galmiche JP. Inter- and intrasubject variability of solid and liquid gastric emptying parameters. A scintigraphic study in healthy subjects and diabetic patients. Dig Dis Sci 1994; 39: 109–15.
  • Prescott LF. Kinetics and metabolism of para-cetamol and phenacetin. Br J Clin Pharmacol 1980; 10: 291–8.
  • Forrest JA, Clements JA, Prescott LF. Clinical pharmacokinetics of paracetamol. Clin Pharmaco-kinet 1982; 7: 93–107.
  • Willems M, Quartero 0, Numans M. How useful is paracetamol absorption as a marker of gastric emptying? A systematic literature study. Dig Dis Sci 2001; 46: 2256–62.
  • Cavallo-Perin P, Aimo G, Mazzillo A, Riccardini F, Pagano G. Gastric emptying of liquids and solids evaluated by acetaminophen test in diabetic patients with and without autonomic neuropathy. Riv Eur Sci Med Pharmacol 1991; 13: 205–9.
  • van Wyk M, Sommers DK, Snyman JR, Moncrieff J. The proportional cumulative area under the curve of paracetamol used as an index of gastric emptying in diabetic patients with symptoms of gastroparesis. Clin Exp Pharmacol Physiol 1995; 22: 637–40.
  • Medhus AW, Sandstad 0, Bredesen J, Husebye E. Delay of gastric emptying by duodenal intubation: sensitive measurement of gastric emptying by the paracetamol absorption test. Aliment Pharmacol Ther 1999; 13: 609–20.
  • Heding L. Radioimmunological determination of human C-peptide in serum. Diabetologia 1975; 11: 541–8.
  • van Wyk M, Sommers DK, Snyman JR, Moncrieff J. A foreshortened method of measur-ing liquid gastric emptying in normal volunteers. Methods Find Exp Clin Pharmacol 1993; 15: 61–6.
  • Price CP, Hammond PM, Scawen MD. Evalua-tion of an enzymic procedure for measurement of acetaminophen. Clin Chem 1983; 29: 358–61.
  • Jeppsson J-0, Jerntorp P, Sundkvist G, Englund H, Nylund V. Measurement of haemoglobin Ai c by a new liquid-chromatographic assay: methodology, clinical utility, and relation to glucose tolerance evaluated. Clin Chem 1986; 32: 1867–72.
  • Liu D, Moberg E, Kollind M, Lins P-E, Adamson U, Macdonald IA. Arterial, arterialized venous, venous and capillary blood glucose measurements in normal man during hyperinsulinaemic eugly-caemia and hypoglycaemia. Diabetologia 1992; 35: 287–90.
  • Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurements. Lancet 1986; 8: 307–10.
  • Näslund E, Bogefors J, Gryback P, Jacobsson H, Hellstrom PM. Gastric emptying: comparison of scintigraphic, polyethylene glycol dilution, and paracetamol tracer assessment techniques. Scand J Gastroenterol 2000; 35: 375–9.
  • Medhus AW, Lofthus CM, Bredesen J, Husebye E. Gastric emptying: the validity of the para-cetamol absorption test adjusted for individual pharmacokinetics. Neurogastroenterol Motil 2001; 13: 179–85.
  • Thompson D, Richelson E, Malagelada J. Pertur-bation of upper gastrointestinal function by cold stress. Gut 1983; 24: 277–83.
  • Rawlins MD, Henderson DB, Hijab AR. Phar-macokinetics of paracetamol (acetaminophen) after intravenous and oral administration. Eur J Clin Pharmacol 1977; 11: 283–6.
  • Jebbink H, Bravenboer B, Akkermans L, vanBerge-Henegouwen G, Smout A. Relationship between dyspeptic symptoms and gastrointestinal motility in patients with type 1 (insulin-dependent) diabetes mellitus. Diabetologia 1993; 36: 948–54.
  • Hebbard GS, Sun WM, Bochner F, Horowitz M. Pharmacokinetic considerations in gastrointestinal motor disorders. Clin Pharmacokinet 1995; 28: 41–66.
  • Sanaka M, Koike Y, Yamamoto T, Mineshita S, Yamaoka S, Hirama S, Tanaka H, Yamanaka M. A reliable and convenient parameter of the rate of paracetamol absorption to measure gastric empty-ing rate of liquids. Int J Clin Pharmacol Ther 1997; 35: 509–13.
  • Endrenyi L, Fritsch S, Yan W. Cmax/AUC is a clearer measure than Cmax for absorption rates in investigations of bioequivalence. Int J Clin Pharmacol Ther Toxicol 1991; 29: 394–9.
  • Lacey LF, Keene ON, Duquesnoy C, Bye A. Evaluation of different indirect measures of rate of drug absorption in comparative pharmacokinetic studies. J Pharm Sci 1994; 83: 212–5.
  • Heading RC, Nimmo J, Prescott LF, Tothill P. The dependence of paracetamol absorption on the rate of gastric emptying. Br J Pharmacol 1973; 47: 415— 21.
  • Maddern G, Miners J, Collins PJ, Jamieson GG. Liquid gastric emptying assessed by direct and indirect techniques: radionuclide labelled liquid emptying compared with a simple paracetamol marker method. Aust NZ J Surg 1985; 55: 203–6.
  • Koizumi F, Kawamura T, Ishimori A, Ebina H, Satoh M. Plasma paracetamol concentrations measured by fluorescence polarization immuno-assay and gastric emptying time. Tohoku J Exp Med 1988; 155: 159–64.
  • Wishart JM, Horowitz M, Morris HA, Need AG, Russo A, Jones KL, Sun WM, Nordin BE. Relationship between fractional calcium absorp-tion and gastric emptying. Eur J Clin Invest 1995; 25: 123–7.
  • Heading RC, Tothill P, McLoughlin GP, Shearman DJ. Gastric emptying rate measurement in man. A double isotope scanning technique for simultaneous study of liquid and solid components of a meal. Gastroenterology 1976; 71: 45–50.
  • Loo FD, Palmer DW, Soergel KH, Kalbfleisch JH, Wood CM. Gastric emptying in patients with diabetes mellitus. Gastroenterology 1984; 86: 485–94.
  • Wright RA, Clemente R, Wathen R. Diabetic gastroparesis: an abnormality of gastric emptying of solids. Am J Med Sci 1985; 289: 240–2.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.