References
- Björkhem I. Mechanism of the bile acid biosynthesis in mammalian liver. Sterol and bile acids., H Danielsson, J Sjövall, editors. Elsevier Science Publisher, Amsterdam 1985; 231–78
- Vlahcevic Z. R., Heuman D. M., Hylemon P. B. Regulation of bile acid synthesis. Hepatology 1991; 13: 590–600
- Princen H., Post S. M., Twisk J. Regulation of the bile acid synthesis. Curr Pharmaceut Design 1997; 3: 59–84
- Gåfvels M., Olin M., Chowdhary B. P., Raudsepp T., Andersson U., Persson B., et al. Structure and chromosomal assignment of the sterol 12alpha‐hydroxylase gene (CYP8B1) in humans and mouse: eukaryotic cytochrome P‐450 gene devoid of introns. Genomics 1999; 56: 184–96
- Ahlberg J., Angelin B., Björkhem I., Einarsson K., Gustafsson J. A., Rafter J. Effects of treatment with chenodeoxycholic acid on liver microsomal metabolism of steroids in man. J Lab Clin Med 1980; 95: 188–94
- Einarsson K., Akerlund J. E., Reihnér E., Björkhem I. 12 alpha‐hydroxylase activity in human liver and its relation to cholesterol 7 alpha‐hydroxylase activity. J Lipid Res 1992; 33: 1591–5
- Duane W. C., Javitt N. B. 27‐hydroxycholesterol: production rates in normal human subjects. J Lipid Res 1999; 40: 1194–9
- Couture P., Otvos J. D., Cupples L. A., Wilson P. W., Schaefer E. J., Ordovas J. M. Association of the A‐204C polymorphism in the cholesterol 7alpha‐hydroxylase gene with variations in plasma low density lipoprotein cholesterol levels in the Framingham Offspring Study. J Lipid Res 1999; 40: 1883–9
- Kovar J., Suchanek P., Hubacek J. A., Poledne R. The A‐204C polymorphism in the cholesterol 7alpha‐hydroxylase (CYP7A1) gene determines the cholesterolemia responsiveness to a high‐fat diet. Physiol Res 2004; 53: 565–8
- Abrahamsson A., Krapivner S., Gustafsson U., Muhrbeck O., Eggertsen G., Johansson I., et al. Common polymorphisms in the CYP7A1 gene do not contribute to variation in rates of bile acid synthesis and plasma cholesterol concentrations. Atherosclerosis 2005; 182: 37–45, Epub 2005 March 3
- van Erpecum K. J., Portincasa P., Stolk M. F., van de Heijning B. J., van der Zaag E. S., van den Broek A. M., et al. Effects of bile salt and phospholipid hydrophobicity on lithogenicity of human gallbladder bile. Eur J Clin Invest 1994; 24: 744–50
- Jüngst D., Müller I., Kullak‐Ublick G. A., Meyer G., Frimberger E., Fischer S. Deoxycholic acid is not related to lithogenic factors in gallbladder bile. J Lab Clin Med 1999; 133: 370–7
- Gustafsson U., Sahlin S., Einarsson C. Biliary lipid composition in patients with cholesterol and pigment gallstones and gallstone‐free subjects: deoxycholic acid does not contribute to formation of cholesterol gallstones. Eur J Clin Invest 2000; 30: 1099–106
- LaRusso N. F., Hoffman N. E., Hofmann A. F., Northfield T. C., Thistle J. L. Effect of primary bile acid ingestion on bile acid metabolism and biliary lipid secretion in gallstone patients. Gastroenterology 1975; 69: 1301–14
- Ahlberg J., Angelin B., Einarsson K. Hepatic 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase activity and biliary lipid composition in man: relation to cholesterol gallstone disease and effects of cholic acid and chenodeoxycholic acid treatment. J Lipid Res 1981; 22: 410–22
- Reihnér E., Björkhem I., Angelin B., Ewerth S., Einarsson K. Bile acid synthesis in humans: regulation of hepatic microsomal cholesterol 7 alpha‐hydroxylase activity. Gastroenterology 1989; 97: 1498–505
- Angelin B., Einarsson K., Leijd B. Biliary lipid composition during treatment with different hypolipidaemic drugs. Eur J Clin Invest 1979; 9: 185–90
- Eggertsen G., Olin M., Andersson U., Ishida H., Kubota S., Hellman U., et al. Molecular cloning and expression of rabbit sterol 12alpha‐hydroxylase. J Biol Chem 1996; 271: 32269–75
- Einarsson K., Hellström K., Kallner M. Bile acid kinetics in relation to sex, serum lipids, body weight, and gallbladder disease in patients with various types of hyperlipoproteinemia. J Clin Invest 1974; 54: 1301–11
- Björkhem I., Eriksson M., Einarsson K. Evidence for a lack of regulatory importance of the 12 alpha‐hydroxylase in formation of bile acids in man: an in vivo study. J Lipid Res 1983; 24: 1451–6