Adiponectin, obesity and atherosclerosis

References

• FAU, F.a. A.O. o.t. U.N. 2005. Population aspects in the reduction of hunger. Available at: http://www.un.org/esa/population/publications/PopAspectsMDG/04_FAO.pdf
   Google Scholar
• World Health Organisation. 2005. Fact sheet: Obesity and overweight. Available at: http://www.who.int/dietphysicalactivity/publications/facts/obesity/en/
   Google Scholar
• World Health Organisation. The World Health Report 2002: Reducing risks, promoting healthy life. World Health Organization, Geneva
   Google Scholar
• Yusuf S., Hawken S., Ounpuu S., Dans T., Avezum A., Lanas F., et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case‐control study. Lancet 2004; 364: 937–52
   PubMed Web of Science ®Google Scholar
• Guerre‐Millo M. Adipose tissue hormones. J Endocrinol Invest 2002; 25: 855–61
   PubMed Web of Science ®Google Scholar
• Scherer P. E., Williams S., Fogliano M., Baldini G., Lodish H. F. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 1995; 270: 26746–9
   PubMed Web of Science ®Google Scholar
• Nakano Y., Tobe T., Choi‐Miura N. H., Mazda T., Tomita M. Isolation and characterization of GBP28, a novel gelatin‐binding protein purified from human plasma. J Biochem (Tokyo) 1996; 120: 803–12
   PubMed Web of Science ®Google Scholar
• Maeda K., Okubo K., Shimomura I., Funahashi T., Matsuzawa Y., Matsubara K. cDNA cloning and expression of a novel adipose specific collagen‐like factor, apM1 (AdiPose Most abundant Gene transcript 1). Biochem Biophys Res Commun 1996; 221: 286–9
   PubMed Web of Science ®Google Scholar
• Hu E., Liang P., Spiegelman B. M. AdipoQ is a novel adipose‐specific gene dysregulated in obesity. J Biol Chem 1996; 271: 10697–703
   PubMed Web of Science ®Google Scholar
• Takahashi M., Arita Y., Yamagata K., Matsukawa Y., Okutomi K., Horie M., et al. Genomic structure and mutations in adipose‐specific gene, adiponectin. Int J Obes Relat Metab Disord 2000; 24: 861–8
   PubMed Web of Science ®Google Scholar
• Yamauchi T., Kamon J., Ito Y., Tsuchida A., Yokomizo T., Kita S., et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 2003; 423: 762–9
   PubMed Web of Science ®Google Scholar
• McCormack F. X., Pattanajitvilai S., Stewart J., Possmayer F., Inchley K., Voelker D. R. The Cys6 intermolecular disulfide bond and the collagen‐like region of rat SP‐A play critical roles in interactions with alveolar type II cells and surfactant lipids. J Biol Chem 1997; 272: 27971–9
   PubMedGoogle Scholar
• Crouch E., Persson A., Chang D., Heuser J. Molecular structure of pulmonary surfactant protein D (SP‐D). J Biol Chem 1994; 269: 17311–19
   PubMed Web of Science ®Google Scholar
• Waki H., Yamauchi T., Kamon J., Ito Y., Uchida S., Kita S., et al. Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin. J Biol Chem 2003; 278: 40352–63
   PubMed Web of Science ®Google Scholar
• Pajvani U. B., Hawkins M., Combs T. P., Rajala M. W., Doebber T., Berger J. P., et al. Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione‐mediated improvement in insulin sensitivity. J Biol Chem 2004; 279: 12152–62
   PubMed Web of Science ®Google Scholar
• Arita Y., Kihara S., Ouchi N., Takahashi M., Maeda K., Miyagawa J., et al. Paradoxical decrease of an adipose‐specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 1999; 257: 79–83
   PubMed Web of Science ®Google Scholar
• Yokota T., Oritani K., Takahashi I., Ishikawa J., Matsuyama A., Ouchi N., et al. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 2000; 96: 1723–32
   PubMed Web of Science ®Google Scholar
• Ouchi N., Kihara S., Funahashi T., Nakamura T., Nishida M., Kumada M., et al. Reciprocal association of C‐reactive protein with adiponectin in blood stream and adipose tissue. Circulation 2003; 107: 671–4
   PubMed Web of Science ®Google Scholar
• Matsuda M., Shimomura I., Sata M., Arita Y., Nishida M., Maeda N., et al. Role of adiponectin in preventing vascular stenosis. The missing link of adipo‐vascular axis. J Biol Chem 2002; 277: 37487–91
   PubMed Web of Science ®Google Scholar
• Duncan B. B., Schmidt M. I., Pankow J. S., Bang H., Couper D., Ballantyne C. M., et al. Adiponectin and the development of type 2 diabetes: the atherosclerosis risk in communities study. Diabetes 2004; 53: 2473–8
   PubMed Web of Science ®Google Scholar
• Spranger J., Kroke A., Mohlig M., Bergmann M. M., Ristow M., Boeing H., et al. Adiponectin and protection against type 2 diabetes mellitus. Lancet 2003; 361: 226–8
   PubMed Web of Science ®Google Scholar
• Snehalatha C., Mukesh B., Simon M., Viswanathan V., Haffner S. M., Ramachandran A. Plasma adiponectin is an independent predictor of type 2 diabetes in Asian Indians. Diabetes Care 2003; 26: 3226–9
   PubMed Web of Science ®Google Scholar
• Lindsay R. S., Funahashi T., Hanson R. L., Matsuzawa Y., Tanaka S., Tataranni P. A., et al. Adiponectin and development of type 2 diabetes in the Pima Indian population. Lancet 2002; 360: 57–8
   PubMed Web of Science ®Google Scholar
• Pischon T., Girman C. J., Hotamisligil G. S., Rifai N., Hu F. B., Rimm E. B. Plasma adiponectin levels and risk of myocardial infarction in men. J Am Med Assoc 2004; 291: 1730–7
   PubMed Web of Science ®Google Scholar
• Pannacciulli N., Vettor R., Milan G., Granzotto M., Catucci A., Federspil G., et al. Anorexia nervosa is characterized by increased adiponectin plasma levels and reduced nonoxidative glucose metabolism. J Clin Endocrinol Metab 2003; 88: 1748–52
   PubMed Web of Science ®Google Scholar
• Delporte M. L., Brichard S. M., Hermans M. P., Beguin C., Lambert M. Hyperadiponectinaemia in anorexia nervosa. Clin Endocrinol (Oxf) 2003; 58: 22–9
   PubMed Web of Science ®Google Scholar
• Wong S. P., Huda M., English P., Bargiotta A., Wilding J. P., Johnson A., et al. Adipokines and the insulin resistance syndrome in familial partial lipodystrophy caused by a mutation in lamin A/C. Diabetologia 2005; 48: 2641–9
   PubMedGoogle Scholar
• Garg A. Acquired and inherited lipodystrophies. N Engl J Med 2004; 350: 1220–34
   PubMed Web of Science ®Google Scholar
• Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., et al. The fat‐derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001; 7: 941–6
   PubMed Web of Science ®Google Scholar
• Cnop M., Havel P. J., Utzschneider K. M., Carr D. B., Sinha M. K., Boyko E. J., et al. Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex. Diabetologia 2003; 46: 459–69
   PubMed Web of Science ®Google Scholar
• Statnick M. A., Beavers L. S., Conner L. J., Corominola H., Johnson D., Hammond C. D., et al. Decreased expression of apM1 in omental and subcutaneous adipose tissue of humans with type 2 diabetes. Int J Exp Diabetes Res 2000; 1: 81–8
   PubMedGoogle Scholar
• Fisher F. M., McTernan P. G., Valsamakis G., Chetty R., Harte A. L., Anwar A. J., et al. Differences in adiponectin protein expression: effect of fat depots and type 2 diabetic status. Horm Metab Res 2002; 34: 650–4
   PubMed Web of Science ®Google Scholar
• Viguerie N., Vidal H., Arner P., Holst C., Verdich C., Avizou S., et al. Adipose tissue gene expression in obese subjects during low‐fat and high‐fat hypocaloric diets. Diabetologia 2005; 48: 123–31
   PubMed Web of Science ®Google Scholar
• Garaulet M., Viguerie N., Porubsky S., Klimcakova E., Clement K., Langin D., et al. Adiponectin gene expression and plasma values in obese women during very‐low‐calorie diet. Relationship with cardiovascular risk factors and insulin resistance. J Clin Endocrinol Metab 2004; 89: 756–60
   PubMed Web of Science ®Google Scholar
• Xydakis A. M., Case C. C., Jones P. H., Hoogeveen R. C., Liu M. Y., Smith E. O., et al. Adiponectin, inflammation, and the expression of the metabolic syndrome in obese individuals: the impact of rapid weight loss through caloric restriction. J Clin Endocrinol Metab 2004; 89: 2697–703
   PubMed Web of Science ®Google Scholar
• Baratta R., Amato S., Degano C., Farina M. G., Patane G., Vigneri R., et al. Adiponectin relationship with lipid metabolism is independent of body fat mass: evidence from both cross‐sectional and intervention studies. J Clin Endocrinol Metab 2004; 89: 2665–71
   PubMed Web of Science ®Google Scholar
• Bobbert T., Rochlitz H., Wegewitz U., Akpulat S., Mai K., Weickert M. O., et al. Changes of adiponectin oligomer composition by moderate weight reduction. Diabetes 2005; 54: 2712–19
   PubMed Web of Science ®Google Scholar
• Wolfe B. E., Jimerson D. C., Orlova C., Mantzoros C. S. Effect of dieting on plasma leptin, soluble leptin receptor, adiponectin and resistin levels in healthy volunteers. Clin Endocrinol (Oxf) 2004; 61: 332–8
   PubMed Web of Science ®Google Scholar
• Weyer C., Funahashi T., Tanaka S., Hotta K., Matsuzawa Y., Pratley R. E., et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 2001; 86: 1930–5
   PubMed Web of Science ®Google Scholar
• Tschritter O., Fritsche A., Thamer C., Haap M., Shirkavand F., Rahe S., et al. Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism. Diabetes 2003; 52: 239–43
   PubMed Web of Science ®Google Scholar
• Behre C. J., Brohall G., Hulthe J., Fagerberg B. Serum adiponectin in a population sample of 64‐year‐old women in relation to glucose tolerance, family history of diabetes, autoimmunity, insulin sensitivity, C‐peptide, and inflammation. Metabolism 2006; 55: 188–94
   PubMed Web of Science ®Google Scholar
• Behre C. J., Fagerberg B., Hulten L. M., Hulthe J. The reciprocal association of adipocytokines with insulin resistance and C‐reactive protein in clinically healthy men. Metabolism 2005; 54: 439–44
   PubMed Web of Science ®Google Scholar
• Gonzalez‐Sanchez J. L., Zabena C. A., Martinez‐Larrad M. T., Fernandez‐Perez C., Perez‐Barba M., Laakso M., et al. An SNP in the adiponectin gene is associated with decreased serum adiponectin levels and risk for impaired glucose tolerance. Obes Res 2005; 13: 807–12
   PubMedGoogle Scholar
• Lacquemant C., Froguel P., Lobbens S., Izzo P., Dina C., Ruiz J. The adiponectin gene SNP+45 is associated with coronary artery disease in Type 2 (non‐insulin‐dependent) diabetes mellitus. Diabet Med 2004; 21: 776–81
   PubMedGoogle Scholar
• Filippi E., Sentinelli F., Romeo S., Arca M., Berni A., Tiberti C., et al. The adiponectin gene SNP+276G>T associates with early‐onset coronary artery disease and with lower levels of adiponectin in younger coronary artery disease patients (age </ = 50 years). J Mol Med 2005; 711–19
   PubMedGoogle Scholar
• Ohashi K., Ouchi N., Kihara S., Funahashi T., Nakamura T., Sumitsuji S., et al. Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease. J Am Coll Cardiol 2004; 43: 1195–200
   PubMedGoogle Scholar
• Hadjadj S., Aubert R., Fumeron F., Pean F., Tichet J., Roussel R., et al. Increased plasma adiponectin concentrations are associated with microangiopathy in type 1 diabetic subjects. Diabetologia 2005; 48: 1088–92
   PubMedGoogle Scholar
• Imagawa A., Funahashi T., Nakamura T., Moriwaki M., Tanaka S., Nishizawa H., et al. Elevated serum concentration of adipose‐derived factor, adiponectin, in patients with type 1 diabetes. Diabetes Care 2002; 25: 1665–6
   PubMed Web of Science ®Google Scholar
• Motoshima H., Wu X., Mahadev K., Goldstein B. J. Adiponectin suppresses proliferation and superoxide generation and enhances eNOS activity in endothelial cells treated with oxidized LDL. Biochem Biophys Res Commun 2004; 315: 264–71
   PubMed Web of Science ®Google Scholar
• Ouchi N., Kihara S., Arita Y., Nishida M., Matsuyama A., Okamoto Y., et al. Adipocyte‐derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte‐derived macrophages. Circulation 2001; 103: 1057–63
   PubMed Web of Science ®Google Scholar
• Ouchi N., Kihara S., Arita Y., Okamoto Y., Maeda K., Kuriyama H., et al. Adiponectin, an adipocyte‐derived plasma protein, inhibits endothelial NF‐kappaB signaling through a cAMP‐dependent pathway. Circulation 2000; 102: 1296–301
   PubMed Web of Science ®Google Scholar
• Ouchi N., Kihara S., Arita Y., Maeda K., Kuriyama H., Okamoto Y., et al. Novel modulator for endothelial adhesion molecules: adipocyte‐derived plasma protein adiponectin. Circulation 1999; 100: 2473–6
   PubMed Web of Science ®Google Scholar
• Bruun J. M., Lihn A. S., Verdich C., Pedersen S. B., Toubro S., Astrup A., et al. Regulation of adiponectin by adipose tissue‐derived cytokines: in vivo and in vitro investigations in humans. Am J Physiol Endocrinol Metab 2003; 285: E527–33
   PubMed Web of Science ®Google Scholar
• Kobashi C., Urakaze M., Kishida M., Kibayashi E., Kobayashi H., Kihara S., et al. Adiponectin inhibits endothelial synthesis of interleukin‐8. Circ Res 2005; 97: 1245–52
   PubMed Web of Science ®Google Scholar
• Otsuka F., Sugiyama S., Kojima S., Maruyoshi H., Funahashi T., Matsui K., et al. Plasma adiponectin levels are associated with coronary lesion complexity in men with coronary artery disease. J Am Coll Cardiol 2006; 48: 1155–62
   PubMed Web of Science ®Google Scholar
• Maruyoshi H., Kojima S., Otsuka F., Funahashi T., Kaikita K., Sugiyama S., et al. Hypoadiponectinemia is associated with coronary artery spasm in men. Circ J 2005; 69: 1154–6
   PubMedGoogle Scholar
• Kumada M., Kihara S., Sumitsuji S., Kawamoto T., Matsumoto S., Ouchi N., et al. Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol 2003; 23: 85–9
   PubMed Web of Science ®Google Scholar
• Dzielinska Z., Januszewicz A., Wiecek A., Demkow M., Makowiecka‐Ciesla M., Prejbisz A., et al. Decreased plasma concentration of a novel anti‐inflammatory protein – adiponectin – in hypertensive men with coronary artery disease. Thromb Res 2003; 110: 365–9
   PubMed Web of Science ®Google Scholar
• Dunajska K., Milewicz A., Jedrzejuk D., Szymczak J., Kuliczkowski W., Salomon P., et al. Plasma adiponectin concentration in relation to severity of coronary atherosclerosis and cardiovascular risk factors in middle‐aged men. Endocrine 2004; 25: 215–21
   PubMed Web of Science ®Google Scholar
• Chen M. P., Tsai J. C., Chung F. M., Yang S. S., Hsing L. L., Shin S. J., et al. Hypoadiponectinemia is associated with ischemic cerebrovascular disease. Arterioscler Thromb Vasc Biol 2005; 25: 821–6
   PubMed Web of Science ®Google Scholar
• Iwashima Y., Horio T., Suzuki Y., Kihara S., Rakugi H., Kangawa K., et al. Adiponectin and inflammatory markers in peripheral arterial occlusive disease. Atherosclerosis 2006; 384–90
   PubMedGoogle Scholar
• Schulze M. B., Shai I., Rimm E. B., Li T., Rifai N., Hu F. B. Adiponectin and future coronary heart disease events among men with type 2 diabetes. Diabetes 2005; 54: 534–9
   PubMed Web of Science ®Google Scholar
• Hulthe J., Hulten L. M., Fagerberg B. Low adipocyte‐derived plasma protein adiponectin concentrations are associated with the metabolic syndrome and small dense low‐density lipoprotein particles: atherosclerosis and insulin resistance study. Metabolism 2003; 52: 1612–14
   PubMed Web of Science ®Google Scholar
• Hotta K., Funahashi T., Arita Y., Takahashi M., Matsuda M., Okamoto Y., et al. Plasma concentrations of a novel, adipose‐specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 2000; 20: 1595–9
   PubMed Web of Science ®Google Scholar
• Kazumi T., Kawaguchi A., Sakai K., Hirano T., Yoshino G. Young men with high‐normal blood pressure have lower serum adiponectin, smaller LDL size, and higher elevated heart rate than those with optimal blood pressure. Diabetes Care 2002; 25: 971–6
   PubMed Web of Science ®Google Scholar
• Okamoto Y., Kihara S., Ouchi N., Nishida M., Arita Y., Kumada M., et al. Adiponectin reduces atherosclerosis in apolipoprotein E‐deficient mice. Circulation 2002; 106: 2767–70
   PubMed Web of Science ®Google Scholar
• Kubota N., Terauchi Y., Yamauchi T., Kubota T., Moroi M., Matsui J., et al. Disruption of adiponectin causes insulin resistance and neointimal formation. J Biol Chem 2002; 277: 25863–6
   PubMed Web of Science ®Google Scholar
• McGill H. C Jr., McMahan C. A. Determinants of atherosclerosis in the young. Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group. Am J Cardiol 1998; 82: 30T–36T
   PubMed Web of Science ®Google Scholar
• Stary H. C., Chandler A. B., Glagov S., Guyton J. R., Insull W Jr., Rosenfeld M. E., et al. A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation 1994; 89: 2462–78
   PubMed Web of Science ®Google Scholar
• Wendelhag I., Gustavsson T., Suurkula M., Berglund G., Wikstrand J. Ultrasound measurement of wall thickness in the carotid artery: fundamental principles and description of a computerized analysing system. Clin Physiol 1991; 11: 565–77
   PubMedGoogle Scholar
• Pignoli P., Tremoli E., Poli A., Oreste P., Paoletti R. Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging. Circulation 1986; 74: 1399–406
   PubMed Web of Science ®Google Scholar
• Lonn E. Carotid artery intima‐media thickness – a new noninvasive gold standard for assessing the anatomic extent of atherosclerosis and cardiovascular risk?. Clin Invest Med 1999; 22: 158–60
   PubMedGoogle Scholar
• Grobbee D. E., Bots M. L. Carotid artery intima‐media thickness as an indicator of generalized atherosclerosis. J Intern Med 1994; 236: 567–73
   PubMed Web of Science ®Google Scholar
• O'Leary D. H., Polak J. F., Kronmal R. A., Manolio T. A., Burke G. L., Wolfson S. K Jr. Carotid‐artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. N Engl J Med 1999; 340: 14–22
   PubMed Web of Science ®Google Scholar
• Ebrahim S., Papacosta O., Whincup P., Wannamethee G., Walker M., Nicolaides A. N., et al. Carotid plaque, intima media thickness, cardiovascular risk factors, and prevalent cardiovascular disease in men and women: the British Regional Heart Study. Stroke 1999; 30: 841–50
   PubMed Web of Science ®Google Scholar
• Lekakis J. P., Papamichael C. M., Cimponeriu A. T., Stamatelopoulos K. S., Papaioannou T. G., Kanakakis J., et al. Atherosclerotic changes of extracoronary arteries are associated with the extent of coronary atherosclerosis. Am J Cardiol 2000; 85: 949–52
   PubMed Web of Science ®Google Scholar
• Mathiesen E. B., Bonaa K. H., Joakimsen O. Echolucent plaques are associated with high risk of ischemic cerebrovascular events in carotid stenosis: the Tromso study. Circulation 2001; 103: 2171–5
   PubMed Web of Science ®Google Scholar
• Bonithon‐Kopp C., Scarabin P. Y., Taquet A., Touboul P. J., Malmejac A., Guize L. Risk factors for early carotid atherosclerosis in middle‐aged French women. Arterioscler Thromb 1991; 11: 966–72
   PubMed Web of Science ®Google Scholar
• Hollander M., Hak A. E., Koudstaal P. J., Bots M. L., Grobbee D. E., Hofman A., et al. Comparison between measures of atherosclerosis and risk of stroke: the Rotterdam Study. Stroke 2003; 34: 2367–72
   PubMed Web of Science ®Google Scholar
• Bots M. L., Hoes A. W., Koudstaal P. J., Hofman A., Grobbee D. E. Common carotid intima‐media thickness and risk of stroke and myocardial infarction: the Rotterdam Study. Circulation 1997; 96: 1432–7
   PubMed Web of Science ®Google Scholar
• Chambless L. E., Heiss G., Folsom A. R., Rosamond W., Szklo M., Sharrett A. R., et al. Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) Study, 1987–1993. Am J Epidemiol 1997; 146: 483–94
   PubMed Web of Science ®Google Scholar
• Iglseder B., Mackevics V., Stadlmayer A., Tasch G., Ladurner G., Paulweber B. Plasma adiponectin levels and sonographic phenotypes of subclinical carotid artery atherosclerosis: data from the SAPHIR Study. Stroke 2005; 36: 2577–82
   PubMed Web of Science ®Google Scholar
• Lo J., Dolan S. E., Kanter J. R., Hemphill L. C., Connelly J. M., Lees R. S., et al. Effects of obesity, body composition, and adiponectin on carotid intima‐media thickness in healthy women. J Clin Endocrinol Metab 2006; 91: 1677–82
   PubMed Web of Science ®Google Scholar
• Pilz S., Horejsi R., Moller R., Almer G., Scharnagl H., Stojakovic T., et al. Early atherosclerosis in obese juveniles is associated with low serum levels of adiponectin. J Clin Endocrinol Metab 2005; 90: 4792–6
   PubMed Web of Science ®Google Scholar
• Jansson P. A., Pellme F., Hammarstedt A., Sandqvist M., Brekke H., Caidahl K., et al. A novel cellular marker of insulin resistance and early atherosclerosis in humans is related to impaired fat cell differentiation and low adiponectin. Faseb J 2003; 17: 1434–40
   PubMed Web of Science ®Google Scholar
• Behre C. J., Brohall G., Hulthe J., Wikstrand J., Fagerberg B. Are serum adiponectin concentrations in a population sample of 64‐year‐old Caucasian women with varying glucose tolerance associated with ultrasound‐assessed atherosclerosis?. J Intern Med 2006 Sep; 260: 238–44
   PubMed Web of Science ®Google Scholar
• Shioji K., Moriguchi A., Moriwaki S., Manabe K., Takeuchi Y., Uegaito T., et al. [Hypoadiponectinemia implies the development of atherosclerosis in carotid and coronary arteries]. J Cardiol 2005; 46: 105–12
   PubMedGoogle Scholar
• Nagasaki T., Inaba M., Hiura Y., Tahara H., Kumeda Y., Shirakawa K., et al. Plasma levels of adiponectin and soluble thrombomodulin in hypothyroid patients with normal thyroid function following levothyroxine replacement therapy. Biomed Pharmacother 2005; 59: 571–7
   PubMedGoogle Scholar
• Matsuda M., Kawasaki F., Yamada K., Kanda Y., Saito M., Eto M., et al. Impact of adiposity and plasma adipocytokines on diabetic angiopathies in Japanese Type 2 diabetic subjects. Diabet Med 2004; 21: 881–8
   PubMed Web of Science ®Google Scholar
• Gungor N., Thompson T., Sutton‐Tyrrell K., Janosky J., Arslanian S. Early signs of cardiovascular disease in youth with obesity and type 2 diabetes. Diabetes Care 2005; 28: 1219–21
   PubMed Web of Science ®Google Scholar
• Hoybye C., Bruun J. M., Richelsen B., Flyvbjerg A., Frystyk J. Serum adiponectin levels in adults with Prader‐Willi syndrome are independent of anthropometrical parameters and do not change with GH treatment. Eur J Endocrinol 2004; 151: 457–61
   PubMedGoogle Scholar
• Shetty G. K., Economides P. A., Horton E. S., Mantzoros C. S., Veves A. Circulating adiponectin and resistin levels in relation to metabolic factors, inflammatory markers, and vascular reactivity in diabetic patients and subjects at risk for diabetes. Diabetes Care 2004; 27: 2450–7
   PubMed Web of Science ®Google Scholar
• Xu A., Chan K. W., Hoo R. L., Wang Y., Tan K. C., Zhang J., et al. Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes. J Biol Chem 2005; 280: 18073–80
   PubMed Web of Science ®Google Scholar
• Isobe T., Saitoh S., Takagi S., Takeuchi H., Chiba Y., Katoh N., et al. Influence of gender, age and renal function on plasma adiponectin level: the Tanno and Sobetsu study. Eur J Endocrinol 2005; 153: 91–8
   PubMed Web of Science ®Google Scholar
• Furuhashi M., Ura N., Higashiura K., Murakami H., Tanaka M., Moniwa N., et al. Blockade of the renin‐angiotensin system increases adiponectin concentrations in patients with essential hypertension. Hypertension 2003; 42: 76–81
   PubMed Web of Science ®Google Scholar
• Clasen R., Schupp M., Foryst‐Ludwig A., Sprang C., Clemenz M., Krikov M., et al. PPARgamma‐activating angiotensin type‐1 receptor blockers induce adiponectin. Hypertension 2005; 46: 137–43
   PubMed Web of Science ®Google Scholar
• Koh K. K., Quon M. J., Han S. H., Chung W. J., Ahn J. Y., Seo Y. H., et al. Additive beneficial effects of losartan combined with simvastatin in the treatment of hypercholesterolemic, hypertensive patients. Circulation 2004; 3687–92
   PubMedGoogle Scholar
• Englund Ogge L., Brohall G., Behre C. J., Schmidt C., Fagerberg B. Alcohol consumption in relation to metabolic regulation, inflammation, and adiponectin in 64‐year‐old Caucasian women: a population‐based study with a focus on impaired glucose regulation. Diabetes Care 2006; 29: 908–13
   PubMedGoogle Scholar
• Choi K. M., Lee J., Lee K. W., Seo J. A., Oh J. H., Kim S. G., et al. Serum adiponectin concentrations predict the developments of type 2 diabetes and the metabolic syndrome in elderly Koreans. Clin Endocrinol (Oxf) 2004; 61: 75–80
   PubMed Web of Science ®Google Scholar
• Looker H. C., Krakoff J., Funahashi T., Matsuzawa Y., Tanaka S., Nelson R. G., et al. Adiponectin concentrations are influenced by renal function and diabetes duration in Pima Indians with type 2 diabetes. J Clin Endocrinol Metab 2004; 89: 4010–17
   PubMedGoogle Scholar
• Saraheimo M., Forsblom C., Fagerudd J., Teppo A. M., Pettersson‐Fernholm K., Frystyk J., et al. Serum adiponectin is increased in type 1 diabetic patients with nephropathy. Diabetes Care 2005; 28: 1410–14
   PubMed Web of Science ®Google Scholar
• Kistorp C., Faber J., Galatius S., Gustafsson F., Frystyk J., Flyvbjerg A., et al. Plasma adiponectin, body mass index, and mortality in patients with chronic heart failure. Circulation 2005; 112: 1756–62
   PubMed Web of Science ®Google Scholar
• Halleux C. M., Takahashi M., Delporte M. L., Detry R., Funahashi T., Matsuzawa Y., et al. Secretion of adiponectin and regulation of apM1 gene expression in human visceral adipose tissue. Biochem Biophys Res Commun 2001; 288: 1102–7
   PubMed Web of Science ®Google Scholar
• Fasshauer M., Klein J., Neumann S., Eszlinger M., Paschke R. Hormonal regulation of adiponectin gene expression in 3T3‐L1 adipocytes. Biochem Biophys Res Commun 2002; 290: 1084–9
   PubMed Web of Science ®Google Scholar
• Hotamisligil G. S., Shargill N. S., Spiegelman B. M. Adipose expression of tumor necrosis factor‐alpha: direct role in obesity‐linked insulin resistance. Science 1993; 259: 87–91
   PubMed Web of Science ®Google Scholar
• Choi K. C., Ryu O. H., Lee K. W., Kim H. Y., Seo J. A., Kim S. G., et al. Effect of PPAR‐alpha and ‐gamma agonist on the expression of visfatin, adiponectin, and TNF‐alpha in visceral fat of OLETF rats. Biochem Biophys Res Commun 2005; 336: 747–53
   PubMed Web of Science ®Google Scholar
• Delporte M. L., Funahashi T., Takahashi M., Matsuzawa Y., Brichard S. M. Pre‐ and post‐translational negative effect of beta‐adrenoceptor agonists on adiponectin secretion: in vitro and in vivo studies. Biochem J 2002; 367: 677–85
   PubMedGoogle Scholar