192
Views
13
CrossRef citations to date
0
Altmetric
Original Article

The combined use of three widely available biochemical markers as predictor of organ failure in critically ill patients

ORCID Icon, ORCID Icon, ORCID Icon, & ORCID Icon
Pages 479-485 | Received 28 Dec 2015, Accepted 12 Jun 2016, Published online: 30 Jun 2016

References

  • Mizock BA. The multiple organ dysfunction syndrome. Dis Mon 2009;55:476–526.
  • Thomson SJ, Cowan ML, Johnston I, Musa S, Grounds M, Rahman TM. ‘Liver function tests’ on the intensive care unit: a prospective, observational study. Intensive Care Med 2009;35:1406–11.
  • Legrand C, Bour JM, Jacob C, Capiaumont J, Martial A, Marc A, Wudtke M, Kretzmer G, Demangel C, Duval D, Hache J. Lactate dehydrogenase (LDH) activity of the cultured eukaryotic cells as marker of the number of dead cells in the medium [corrected]. J Biotechnol 1992;25:231–43.
  • Thoresen M, Liu X, Jary S, Brown E, Sabir H, Stone J, Cowan F, Karlsson M. Lactate dehydrogenase in hypothermia-treated newborn infants with hypoxic-ischaemic encephalopathy. Acta Paediatr 2012;101:1038–44.
  • Karlsson M, Dung KT, Thi TL, Borgstrom E, Jonstam K, Kasstrom L, Winbladh B. Lactate dehydrogenase as an indicator of severe illness in neonatal intensive care patients: a longitudinal cohort study. Acta Paediatr 2012;101:1225–31.
  • Karlsson M, Wiberg-Itzel E, Chakkarapani E, Blennow M, Winbladh B, Thoresen M. Lactate dehydrogenase predicts hypoxic ischaemic encephalopathy in newborn infants: a preliminary study. Acta Paediatr 2010;99:1139–44.
  • Reddy S, Dutta S, Narang A. Evaluation of lactate dehydrogenase, creatine kinase and hepatic enzymes for the retrospective diagnosis of perinatal asphyxia among sick neonates. Indian Pediatr 2008;45:144–7.
  • Lackmann GM, Tollner U. The predictive value of elevation in specific serum enzymes for subsequent development of hypoxic-ischemic encephalopathy or intraventricular hemorrhage in full-term and premature asphyxiated newborns. Neuropediatrics 1995;26:192–8.
  • Morini F, di Crosta I, Ronchetti MP, Dituri F, Nahom A, Corchia C, Bagolan P. Lactate dehydrogenase activity is increased in plasma of infants with advanced necrotizing enterocolitis. Pediatr Surg Int 2008;24:705–9.
  • Goldwasser P, Feldman J. Association of serum albumin and mortality risk. J Clin Epidemiol 1997;50:693–703.
  • Yap FH, Joynt GM, Buckley TA, Wong EL. Association of serum albumin concentration and mortality risk in critically ill patients. Anaesth Intensive Care 2002;30:202–7.
  • Fleck A, Raines G, Hawker F, Trotter J, Wallace PI, Ledingham IM, Calman KC. Increased vascular permeability: a major cause of hypoalbuminaemia in disease and injury. Lancet 1985;1:781–4.
  • Bradley JA, Cunningham KJ, Jackson VJ, Hamilton DNH, Ledingham IM. Serum protein levels in critically ill surgical patients . Intensive Care Med 1981;7:291–5.
  • Karlsson M, Tooley JR, Satas S, Hobbs CE, Chakkarapani E, Stone J, Porter H, Thoresen M. Delayed hypothermia as selective head cooling or whole body cooling does not protect brain or body in newborn pig subjected to hypoxia-ischemia. Pediatr Res 2008;64:74–8.
  • Satas S, Loberg EM, Porter H, Whitelaw A, Steen PA, Thoresen M. Effect of global hypoxia-ischaemia followed by 24 h of mild hypothermia on organ pathology and biochemistry in a newborn pig survival model. Biol Neonate 2003;83:146–56.
  • Vats P, Singh SN, Kumria MM, Ranganathan S, Arora MP, Jain CL, Sridharan K. Effect of hypoxia on the circulating levels of essential mineral elements in rats. J Environ Biol 2001;22:277–82.
  • Carroll RG, Iams SG, Pryor WH Jr, Allison EJ Jr. Serum magnesium increases following severe hemorrhage in dogs blocked by verapamil treatment. Resuscitation 1990;19:41–52.
  • Broner CW, Stidham GL, Westenkirchner DF, Tolley EA. Hypermagnesemia and hypocalcemia as predictors of high mortality in critically ill pediatric patients. Crit Care Med 1990;18:921–8.
  • Haider DG, Lindner G, Ahmad SS, Sauter T, Wolzt M, Leichtle AB, Fiedler GM, Exadaktylos AK, Fuhrmann V. Hypermagnesemia is a strong independent risk factor for mortality in critically ill patients: results from a cross-sectional study. Eur J Int Med 2015;26:504–7.
  • Metnitz PG, Moreno RP, Almeida E, Jordan B, Bauer P, Campos RA, Iapichino G, Edbrooke D, Capuzzo M, Le Gall JR, Investigators S. SAPS 3 – from evaluation of the patient to evaluation of the intensive care unit. Part 1: objectives, methods and cohort description. Intensive Care Med 2005;31:1336–44.
  • Moreno RP, Metnitz PG, Almeida E, Jordan B, Bauer P, Campos RA, Iapichino G, Edbrooke D, Capuzzo M, Le Gall JR, Investigators S. SAPS 3 – from evaluation of the patient to evaluation of the intensive care unit. Part 2: development of a prognostic model for hospital mortality at ICU admission. Intensive Care Med 2005;31:1345–55.
  • Vincent J, Moreno R, Takala J, Willatts S, De Mendonca A, Bruining H, Reinhart C, Suter P, Thijs L. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 1996;22:707–10.
  • Vincent JL, de Mendonca A, Cantraine F, Moreno R, Takala J, Suter PM, Sprung CL, Colardyn F, Blecher S. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on “sepsis-related problems” of the European Society of Intensive. Care Medicine. Crit Care Med 1998;26:1793–800.
  • Ferreira FL, Bota DP, Bross A, Melot C, Vincent JL. Serial evaluation of the SOFA score to predict outcome in critically ill patients. JAMA 2001;286:1754–8.
  • Moreno R, Vincent J, Matos R, Mendonca A, Cantraine F, Thijs L, Takala J, Sprung C, Antonelli M, Bruining H, Willatts S. The use of maximum SOFA score to quantify organ dysfunction/failure in intensive care. Results of a prospective, multicentre study. Working Group on Sepsis related Problems of the ESICM. Intensive Care Med 1999;25:686–96.
  • Takano Y, Sakamoto O, Suga M, Muranaka H, Ando M. Prognostic factors of nosocomial pneumonia in general wards: a prospective multivariate analysis in Japan. Respir Med 2002;96:18–23.
  • Birrer R, Takuda Y, Takara T. Hypoxic hepatopathy: pathophysiology and prognosis. Intern Med 2007;46:1063–70.
  • Rawson JS, Achord JL. Shock liver. South Med J 1985;78:1421–5.
  • Brienza N, Dalfino L, Cinnella G, Diele C, Bruno F, Fiore T. Jaundice in critical illness: promoting factors of a concealed reality. Intensive Care Med 2006;32:267–74.
  • Fowler RA, Lapinsky SE, Hallett D, Detsky AS, Sibbald WJ, Slutsky AS, Stewart TE, Toronto SCCG. Critically ill patients with severe acute respiratory syndrome. JAMA 2003;290:367–73.
  • Tejera A, Santolaria F, Diez ML, Aleman-Valls MR, Gonzalez-Reimers E, Martinez-Riera A, Milena-Abril A. Prognosis of community acquired pneumonia (CAP): value of triggering receptor expressed on myeloid cells-1 (TREM-1) and other mediators of the inflammatory response. Cytokine 2007;38:117–23.
  • Lemasters JJ, Stemkowski CJ, Ji S, Thurman RG. Cell surface changes and enzyme release during hypoxia and reoxygenation in the isolated, perfused rat liver. J Cell Biol 1983;97:778–86.
  • Pierrakos C, Vincent J-L. Sepsis biomarkers: a review. Crit Care 2010;14:R15.
  • Lobo SM, Lobo FR, Bota DP, Lopes-Ferreira F, Soliman HM, Melot C, Vincent JL. C-reactive protein levels correlate with mortality and organ failure in critically ill patients. Chest 2003;123:2043–9.
  • Wacker C, Prkno A, Brunkhorst FM, Schlattmann P. Procalcitonin as a diagnostic marker for sepsis: a systematic review and meta-analysis. Lancet Infect Dis 2013;13:426–35.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.