Pre-analytical phase management: a review of the procedures from patient preparation to laboratory analysis

References

• Clinical Laboratory Standards Institute. Quality management system: development and management of laboratory documents. CLSI QMSo2-A6 document. 6th ed. Wayne (PA): Clinical Laboratory Standards Institute; 2013.
   Google Scholar
• Lundberg G. Acting on significant laboratory results. JAMA 1981;245:1762–3.
   PubMed Web of Science ®Google Scholar
• Valenstein PN, Sirota RL. Identification errors in pathology and laboratory medicine. Clin Lab Med 2004;24:979–96.
   PubMed Web of Science ®Google Scholar
• Schiff GD, Hasan O, Kim S, Abrams R, Cosby K, Lambert BL, Elstein AS, Hasler S, Kabongo ML, Krosnjar N, Odwazny R, Wisniewski MF, McNutt RA. Diagnostic error in medicine: analysis of 583 physician-reported errors. Arch Intern Med 2009;169:1881–7.
   PubMedGoogle Scholar
• Nilsson K, Grankvist K, Juthberg C, Brulin C, Söderberg J. Deviations from venous blood specimen collection guideline adherence among senior nursing students. Nurse Educ Today 2014;34:237–42.
   PubMed Web of Science ®Google Scholar
• Sarkozi L, Simson E, Ramanathan L. The effects of total laboratory automation on the management of a clinical chemistry laboratory. Retrospective analysis of 36 years. Clin Chim Acta 2003;329:89–94.
   PubMed Web of Science ®Google Scholar
• Tatsumi N, Okuda K, Tsuda I. A new direction in automated laboratory testing in Japan: five years of experience with total laboratory automation system management. Clin Chim Acta 1999;290:93–108.
   PubMed Web of Science ®Google Scholar
• Graber ML, Franklin N, Gordon R. Diagnostic error in internal medicine. Arch Intern Med 2005;165:1493–9.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Picheth G, Guidi GC. The effective reduction of tourniquet application time after minor modification of the CLSI H03-A6 blood collection procedure. Biochem Med 2013;23:308–15.
   Web of Science ®Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Picheth G, Guidi GC. Laboratory diagnostics and quality of blood collection. J Med Biochem 2015; 34:288–94.
   PubMed Web of Science ®Google Scholar
• Simundic AM, Cornes MP, Grankvist K, Lippi G, Nybo M. Standardization of collection requirements for fasting samples: For the Working Group on Preanalytical Phase (WG-PA) of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM). Clin Chim Acta 2014;432:33–7.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Salvagno GL, Lippi G, Danese E, Gelati M, Montagnana M, Picheth G, Guidi GC. Could light meal jeopardize laboratory coagulation tests? Biochem Med 2014;24:343–9.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Salvagno GL, Lippi G, Gelati M, Montagnana M, Danese E, Picheth G, Guidi GC. Influence of a regular, standardized meal on clinical chemistry analytes. Ann Lab Med 2012;32:250–6.
   PubMed Web of Science ®Google Scholar
• Lippi G, Lima-Oliveira G, Salvagno GL, Montagnana M, Gelati M, Picheth G, Duarte AJ, Franchini M, Guidi GC. Influence of a light meal on routine haematological tests. Blood Transfus 2010;8:94–9.
   PubMed Web of Science ®Google Scholar
• Guidi GC, Simundic AM, Salvagno GL, Aquino JL, Lima-Oliveira G. To avoid fasting time, more risk than benefits. Clin Chem Lab Med 2015;53:e261–4.
   PubMed Web of Science ®Google Scholar
• Sanchis-Gomar F, Lippi G. Physical activity: an important preanalytical variable. Biochem Med (Zagreb) 2014;24:68–79.
   PubMed Web of Science ®Google Scholar
• Young DS, Effects of drugs on clinical laboratory tests. 5th ed. Washington: AACC Press; 2000.
   Google Scholar
• International Organization for Standardization (ISO). Stainless steel needle tubing for manufacture of medical devices. Amendment 1. ISO 9626 document. Geneva, Switzerland: ISO; 2001.
   Google Scholar
• Ernst DJ, Ernst C. Phlebotomy tools of the trade. Home Healthcare Nurse 2002;20:151–3.
   PubMedGoogle Scholar
• Lippi G, Salvagno GL, Montagnana M, Brocco G, Guidi GC. Influence of the needle bore size used for collecting venous blood samples on routine clinical chemistry testing. Clin Chem Lab Med 2006;44:1009–14.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Guidi GC, Salvagno GL, Montagnana M, Rego FGM, Lippi G, Picheth G. Is phlebotomy part of the dark side in the clinical laboratory struggle for quality? Lab Med 2012;43:172–6.
   Web of Science ®Google Scholar
• International Organization for Standardization (ISO). Medical laboratories: requirements for quality and competence ISO document 15189. Geneva, Switzerland: ISO; 2012.
   Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Picheth G, Guidi GC. Pre analytical management: serum vacuum tubes validation for routine clinical chemistry. Biochem Med (Zagreb) 2012;22:180–6.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Picheth G, Guidi GC. Sodium citrate vacuum tubes validation: preventing preanalytical variability in routine coagulation testing. Blood Coagul Fibrinolysis 2013;24:252–5.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Poli G, Solero GP, Picheth G, Guidi GC. K3EDTA vacuum tubes validation for routine hematological testing. ISRN Hematol 2012;2012:875357.
   PubMedGoogle Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Poli G, Solero GP, Picheth G, Guidi GC. Brand of dipotassium EDTA vacuum tube as a new source of pre-analytical variability in routine haematology testing. Br J Biomed Sci 2013;70:6–9.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Salvagno GL, Lippi G, Brocco G, Voi M, Montagnana M, Picheth G, Guidi GC. Quality management of preanalytical phase: impact of lithium heparin vacuum tubes changes on clinical chemistry. Accred Qual Assur 2013;18:429–34.
   Web of Science ®Google Scholar
• Bowen RAR, Remaley AT. Interferences from blood collection tube components on clinical chemistry assays. Biochem Med (Zagreb) 2014;24:31–44.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Picheth G, Guidi GC. Different manufacturers of syringes: a new source of variability in blood gas, acid-base balance and related laboratory test? Clin Biochem 2012;45:683–7.
   PubMed Web of Science ®Google Scholar
• Clinical Laboratory Standards Institute. Procedures for the collection of diagnostic blood specimens by venipuncture. CLSI H3-A6 document. 6th ed. Wayne, PA: Clinical Laboratory Standards Institute; 2007 WorldCat]
   Google Scholar
• World Health Organization (WHO). WHO guidelines on drawing blood: best practices in phlebotomy. Geneva: WHO Press; 2010.
   Google Scholar
• Lippi G, Salvagno GL, Lima-Oliveira G, Brocco G, Danese E, Guidi GC. Postural change during venous blood collection is a major source of bias in clinical chemistry testing. Clin Chim Acta 2015;440:164–8.
   PubMed Web of Science ®Google Scholar
• Lippi G, Salvagno GL, Lima-Oliveira G, Montagnana M, Danese E, Guidi GC. Circulating cardiac troponin T is not influenced by postural changes during venous blood collection. Int J Cardiol 2014;177:1076–7.
   PubMed Web of Science ®Google Scholar
• Lippi G, Salvagno GL, Lima-Oliveira G, Danese E, Favaloro EJ, Guidi GC. Influence of posture on routine hemostasis testing. Blood Coagul Fibrinolysis 2015;26:716–19.
   PubMed Web of Science ®Google Scholar
• Dixon M, Paterson CR. Posture and the composition of plasma. Clin Chem 1978;24:824–6.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G. Standardizing patient’s posture during blood collection by venipuncture. Avicenna J Med Biochem 2016;4:e33936.
   Google Scholar
• Calfee DP, Farr BM. Comparison of four antiseptic preparations for skin in the prevention of contamination of percutaneously drawn blood cultures: a randomized trial. J Clin Microbiol 2002;40:1660–5.
   PubMed Web of Science ®Google Scholar
• Simundic AM, Topic E, Nikolac N, Lippi G. Hemolysis detection and management of hemolyzed specimens. Biochemia Medica 2010;20:154–9.
   Web of Science ®Google Scholar
• Lippi G, Plebani M, Di Somma S, Cervellin G. Hemolyzed specimens: a major challenge for emergency departments and clinical laboratories. Crit Rev Clin Lab Sci 2011;48:143–53.
   PubMed Web of Science ®Google Scholar
• Salvagno GL, Danese E, Lima-Oliveira G, Guidi GC, Lippi G. Avoidance to wipe alcohol before venipuncture is not a source of spurious hemolysis. Biochem Med (Zagreb) 2013;23:201–5.
   PubMed Web of Science ®Google Scholar
• Yamada K, Yamada K, Katsuda I, Hida T. Cubital fossa venipuncture sites based on anatomical variations and relationships of cutaneous veins and nerves. Clin Anat 2008;21:307–13.
   PubMed Web of Science ®Google Scholar
• Dugan L, Leech L, Speroni KG, Corriher J. Factors affecting hemolysis rates in blood samples drawn from newly placed IV sites in the emergency department. J Emerg Nurs 2005;31:338–45.
   PubMed Web of Science ®Google Scholar
• Lippi G, Avanzini P, Aloe R, Cervellin G. Blood collection from intravenous lines: is one drawing site better than others? Lab Med 2014;45:172–5.
   PubMed Web of Science ®Google Scholar
• Lippi G, Salvagno GL, Montagnana M, Franchini M, Guidi GC. Venous stasis and routine hematologic testing. Clin Lab Haematol 2006;28:332–7.
   PubMedGoogle Scholar
• Lippi G, Salvagno GL, Montagnana M, Guidi GC. Short-term venous stasis influences routine coagulation testing. Blood Coagul Fibrinolysis 2005;16:453–8.
   PubMed Web of Science ®Google Scholar
• Lippi G, Salvagno GL, Montagnana M, Brocco G, Guidi GC. Influence of short-term venous stasis on clinical chemistry testing. Clin Chem Lab Med 2005;43:869–75.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Mangueira C, Sumita N, Picheth G, Guidi GC, Scartezini M. New ways to deal with known preanalytical issues: use of transilluminator instead of tourniquet for easing vein access and eliminating stasis on clinical biochemistry. Biochemia Medica 2011;21:152–9.
   Web of Science ®Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Scartezini M, Guidi GC, Picheth G. Transillumination: a new tool to eliminate the impact of venous stasis during the procedure for the collection of diagnostic blood specimens for routine haematological testing. Int J Lab Hematol 2011;33:457–62.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Salvagno GL, Lippi G, Montagnana M, Scartezini M, Picheth G, Guidi GC. Elimination of the venous stasis error for routine coagulation testing by transillumination. Clin Chim Acta 2011;412:1482–4.
   PubMed Web of Science ®Google Scholar
• Weiss RA, Goldman MP. Transillumination mapping prior to ambulatory phlebectomy. Dermatol Surg 1998;24:447–50.
   PubMed Web of Science ®Google Scholar
• AccuVein. Exclusive Distribution by Becton, Dickinson and Co. 2016. Available from: http://www.accuvein.com/how-to-buy/international/exclusive-distribution-by-becton-dickinson-and-co/ (last accessed 8 September 2016).
   Google Scholar
• Christie Medical Holding. Christie distributor inquiry form 2016. 2016. Available from: https://www.christiemed.com/how-to-buy/veinviewer-distributors (last accessed 8 September 2016).
   Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Picheth G, Guidi GC. Impact of the phlebotomy training based on CLSI/NCCLS H03-A6 – procedures for the collection of diagnostic blood specimens by venipuncture. Biochem Med (Zagreb) 2012;22:342–51.
   PubMed Web of Science ®Google Scholar
• Baxter A, Lawson M. Concerns with the methodology, analysis and discussion of the Buzzy® and transillumination comparison article. Blood Transfus 2014;12:S3–S5.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Campelo MD, Tajra KS, dos Santos Gomes F, Valentim CD, Romano SJ, Picheth G, Guidi GC. A new device to relieve venipuncture pain can affect haematology test results. Blood Transfus 2014;12:s6–s10.
   PubMed Web of Science ®Google Scholar
• Don BR, Sebastian A, Cheitlin M, Christiansen M, Schambelan M. Pseudohyperkalemia caused by fist clenching during phlebotomy. N Engl J Med 1990;322:1290–2.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Guidi GC, Salvagno GL, Brocco G, Danese E, Lippi G. Estimation of the imprecision on clinical chemistry testing due to fist clenching and maintenance during venipuncture. Clin Biochem 2016;49:1364–7.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Guidi GC, Salvagno GL, Lippi G. Impact of fist clenching and maintenance during blood collection by venipuncture for routine hematology testing. J Clin Lab Anal 2016. [Epub ahead of print]. doi: 10.1002/jcla.22108
   PubMed Web of Science ®Google Scholar
• Lippi G, Lima-Oliveira G, Guidi GC. Does fist pumping/clenching during venipuncture activate blood coagulation? Blood Coagul Fibrinolysis 2016;27:357–8.
   PubMed Web of Science ®Google Scholar
• Banfi G, Salvagno GL, Lippi G. The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Clin Chem Lab Med 2007;45:565–76.
   PubMed Web of Science ®Google Scholar
• Calam RR, Cooper MH. Recommended order of draw for collecting blood specimens into additive-containing tubes. Clin Chem 1982;28:1399.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Salvagno GL, Danese E, Brocco G, Guidi GC, Lippi G. Contamination of lithium heparin blood by k2-ethylenediaminetetraacetic acid (EDTA): an experimental evaluation. Biochem Med (Zagreb) 2014;24:359–67.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Salvagno GL, Danese E, Favaloro EJ, Guidi GC, Lippi G. Sodium citrate blood contamination by K2-ethylenediaminetetraacetic acid (EDTA): impact on routine coagulation testing. Int J Lab Hematol 2015;37:403–9.
   PubMed Web of Science ®Google Scholar
• Davidson DF. Effects of contamination of blood specimens with liquid potassium-EDTA anticoagulant. Ann Clin Biochem 2002;39:273–80.
   PubMed Web of Science ®Google Scholar
• Cornes MP, Davidson F, Darwin L, Gay C, Redpath M, Waldron JL, Ford C, Gama R. Multi-centre observational study of spurious hyperkalaemia due to EDTA contamination. Clin Lab 2010;56:597–9.
   PubMed Web of Science ®Google Scholar
• Cornes MP, Sulaiman RA, Whitehead SJ, Othonos N, Ford C, Gama R. Incorrect order of draw of blood samples does not causes potassium EDTA sample contamination. Br J Biomed Sci 2012;69:1–2.
   PubMed Web of Science ®Google Scholar
• Salvagno GL, Lima-Oliveira G, Brocco G, Danese E, Guidi GC, Lippi G. The order of draw: myth or science? Clin Chem Lab Med 2013;51:2281–5.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Picheth G, Guidi GC. Incorrect order of draw could be mitigate the patient safety: a phlebotomy management case report. Biochem Med (Zagreb) 2013;23:218–23.
   PubMed Web of Science ®Google Scholar
• Sharratt CL, Gilbert CJ, Cornes MC, Ford C, Gama R. EDTA sample contamination is common and often undetected, putting patients at unnecessary risk of harm. Int J Clin Pract 2009;63:1259–62.
   PubMed Web of Science ®Google Scholar
• Cornes M, van Dongen-Lases E, Grankvist K, Ibarz M, Kristensen G, Lippi G, Nybo M, Simundic AM. Working Group for Preanalytical Phase (WG-PRE) European Federation of Clinical Chemistry and Laboratory Medicine (EFLM). Order of blood draw: opinion Paper by the European Federation for Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase (WG-PRE). Clin Chem Lab Med 2017;55:27–31.
   PubMed Web of Science ®Google Scholar
• Parenmark A, Landberg E. To mix or not to mix venous blood samples collected in vacuum tubes? Clin Chem Lab Med 2011;49:2061–3.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Brocco G, Gaino S, Dima F, Volanski W, Rego FGM, Picheth G, Guidi GC. Processing of diagnostic blood specimens: is it really necessary to mix primary blood tubes after collection with evacuated tube system? Biopreserv Biobank 2014;12:53–9.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Montagnana M, Gelati M, Volanski W, Boritiza KC, Picheth G, Guidi GC. Effects of vigorous mixing of blood vacuum tubes on laboratory test results. Clin Biochem 2013;46:250–4.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Picheth G, Guidi GC. Phlebotomist labelling primary blood tubes for clinical laboratory tests: an important step to medical diagnostics. J Med Diagn Meth 2014;3:E111.
   Google Scholar
• Söderberg J, Brulin C, Grankvist K, Wallin O. Preanalytical errors in primary healthcare: a questionnaire study of information search procedures, test request management and test tube labelling. Clin Chem Lab Med 2009;47:195–201.
   PubMed Web of Science ®Google Scholar
• Wallin O, Soderberg J, Van Guelpen B, Stenlund H, Grankvist K, Brulin C. Preanalytical venous blood sampling practices demand improvement – a survey of test-request management, test-tube labelling and information search procedures. Clin Chim Acta 2008;391:91–7.
   PubMed Web of Science ®Google Scholar
• Hawkins R. Specimen labelling: before or after collection? Clin Chem Lab Med 2011;49:2119–20.
   PubMed Web of Science ®Google Scholar
• Nikolac N, Supak-Smolcic V, Simundic AM, Celap I. Croatian Society of Medical Biochemistry and Laboratory Medicine: national recommendations for venous blood sampling. Biochem Med 2013;23:242–54.
   PubMed Web of Science ®Google Scholar
• Simundic AM, Church S, Cornes MP, Grankvist K, Lippi G, Nybo M, Nikolac N, van Dongen-Lases E, Eker P, Kovalevskaya S, Kristensen GB, Sprongl L, Sumarac Z. Compliance of blood sampling procedures with the CLSI H3-A6 guidelines: an observational study by the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) working group for the preanalytical phase (WG-PRE). Clin Chem Lab Med 2015;53:1321–31.
   PubMed Web of Science ®Google Scholar
• Guss DA, Chan TC, Killeen JP. The impact of a pneumatic tube and computerized physician order management on laboratory turnaround time. Ann Emerg Med 2008;51:181–5.
   PubMed Web of Science ®Google Scholar
• Fernandes CM, Worster A, Eva K, Hill S, McCallum C. Pneumatic tube delivery system for blood samples reduces turnaround times without affecting sample quality. J Emerg Nurs 2006;32:139–43.
   PubMed Web of Science ®Google Scholar
• Keshgegian A, Bull G. Evaluation of a soft-handling computerized pneumatic tube specimen delivery system. Effects on analytical results and turnaround time. Am J Clin Pathol 1992;97:535–40.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Dima F, Brocco G, Picheth G, Guidi GC. Management of preanalytical phase for routine hematological testing: is the pneumatic tube system a source of laboratory variability or an important facility tool? Int J Lab Hematol 2014;36:e37–40.
   PubMed Web of Science ®Google Scholar
• Wallin O, Soderberg J, Grankvist K, Jonsson PA, Hultdin J. Preanalytical effects of pneumatic tube transport on routine haematology, coagulation parameters, platelet function and global coagulation. Clin Chem Lab Med 2008;46:1443–9.
   PubMed Web of Science ®Google Scholar
• Lippi G, Lima-Oliveira G, Nazer SC, Moreira ML, Souza RF, Salvagno GL, Montagnana M, Scartezini M, Picheth G, Guidi GC. Suitability of a transport box for blood sample shipment over a long period. Clin Biochem 2011;44:1028–9.
   PubMed Web of Science ®Google Scholar
• Lippi G, Salvagno GL, Danese E, Lima-Oliveira G, Brocco G, Guidi GC. Inversion of lithium heparin gel tubes after centrifugation is a significant source of bias in clinical chemistry testing. Clin Chim Acta 2014;436:183–7.
   PubMed Web of Science ®Google Scholar
• Zaninotto M, Plebani M. The hospital central laboratory: automation, integration and clinical usefulness. Clin Chem Lab Med 2010;48:911–7.
   PubMed Web of Science ®Google Scholar
• Hawker CD. Laboratory automation: total and subtotal. Clin Lab Med 2007;27:749–70, vi.
   PubMed Web of Science ®Google Scholar
• Hawker CD, Roberts WL, DaSilva A, Stam GD, Owen WE, Curtis D, Choi BS, Ring TA. Development and validation of an automated thawing and mixing work cell. Clin Chem 2007;53:2209–11.
   PubMed Web of Science ®Google Scholar
• Hawker CD, Roberts WL, Garr SB, Hamilton LT, Penrose JR, Ashwood ER, Weiss RL. Automated transport and sorting system in a large reference laboratory: part 2. Implementation of the system and performance measures over three years. Clin Chem 2002;48:1761–7.
   PubMed Web of Science ®Google Scholar
• Hawker CD, Garr SB, Hamilton LT, Penrose JR, Ashwood ER, Weiss RL. Automated transport and sorting system in a large reference laboratory: part 1. Evaluation of needs and alternatives and development of a plan. Clin Chem 2002;48:1751–60.
   PubMed Web of Science ®Google Scholar
• Hawker CD, Schlank MR. Development of standards for laboratory automation. Clin Chem 2000;46:746–50.
   PubMed Web of Science ®Google Scholar
• Lima-Oliveira G, Lippi G, Salvagno GL, Danese E, Montagnana M, Brocco G, Voi M, Picheth G, Guidi GC. Does laboratory automation for the preanalytical phase improve data quality? J Lab Autom 2013;18:375–81.
   PubMedGoogle Scholar
• Simundic AM, Cornes MP, Grankvist K, Lippi G, Nybo M, Ceriotti F, Theodorsson E, Panteghini M. Colour coding for blood collection tube closures: a call for harmonisation. Clin Chem Lab Med 2015;53:371–6.
   PubMed Web of Science ®Google Scholar
• Forsman RW. Why is the laboratory an afterthought for managed care organizations? Clin Chem 1996;42:813–16.
   PubMed Web of Science ®Google Scholar
• Hallworth MJ. The ‘70% claim’: what is the evidence base? Ann Clin Biochem 2011;48:487–8.
   PubMed Web of Science ®Google Scholar
• Lippi G, Cornes MP, Grankvist K, Nybo M, Simundic AM. Working Group for Preanalytical P, European Federation of Clinical C, Laboratory M. EFLM WG-preanalytical phase opinion paper: local validation of blood collection tubes in clinical laboratories. Clin Chem Lab Med 2016;54:755–60.
   PubMed Web of Science ®Google Scholar
• Giavarina D, Banfi G, Daves M, Dolci A, Santarcangeli DF, Lima-Oliveira G, Miconi V, Milanesi B, Montagnana M, Morandini M, Piva E, Salvagno GL, Troiano T, Lippi G. Blood collection systems in clinical laboratories: local adaptation of the EFLM guidelines. Biochimica Clinica 2016;40:347–52.
   Web of Science ®Google Scholar