Effects of a highly controlled carbohydrate-reduced high-protein diet on markers of oxidatively generated nucleic acid modifications and inflammation in weight stable participants with type 2 diabetes; a randomized controlled trial

References

• Chaturvedi N. The burden of diabetes and its complications: trends and implications for intervention. Diabetes Res Clin Pract. 2007;76:3–12.
   PubMed Web of Science ®Google Scholar
• Einarson TR, Acs A, Ludwig C, et al. Prevalence of cardiovascular disease in type 2 diabetes: a systematic literature review of scientific evidence from across the world in 2007-2017. Cardiovasc Diabetol. 2018;17(1):83.
   PubMed Web of Science ®Google Scholar
• Association, American Diabetes 5. Lifestyle management: standards of medical care in diabetes – 2019. Diabetes Care. 2019;42:46–60.
   Web of Science ®Google Scholar
• Wylie-Rosett J, Hu FB. Nutritional strategies for prevention and management of diabetes: consensus and uncertainties. Diabetes Care. 2019;42(5):727–730.
   PubMed Web of Science ®Google Scholar
• Kjaer LK, Cejvanovic V, Henriksen T, et al. Cardiovascular and all-cause mortality risk associated with urinary excretion of 8-oxoGuo, a biomarker for RNA oxidation, in patients with type 2 diabetes: a prospective cohort study. Diabetes Care. 2017;40(12):1771–1778.
   PubMed Web of Science ®Google Scholar
• Broedbaek K, Siersma V, Henriksen T, et al. Urinary markers of nucleic acid oxidation and long-term mortality of newly diagnosed type 2 diabetic patients. Diabetes Care. 2011;34(12):2594–2596.
   PubMed Web of Science ®Google Scholar
• Broedbaek K, Siersma V, Henriksen T, et al. Association between urinary markers of nucleic acid oxidation and mortality in type 2 diabetes: a population-based cohort study. Diabetes Care. 2013;36(3):669–676.
   PubMed Web of Science ®Google Scholar
• Danesh J, Whincup P, Walker M, et al. Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses. Br Med J. 2000;321(7255):199–204.
   PubMed Web of Science ®Google Scholar
• Shi G, Men L, Yu C, et al. Atherosclerosis associated with dynamic inflammation changes after multifactorial intervention in short-duration type 2 diabetes: a randomized, controlled, 10-year follow-up trial. J Diabetes Complications. 2017;31(8):1286–1292.
   PubMed Web of Science ®Google Scholar
• Ofstad AP, Gullestad L, Orvik E, et al. Interleukin-6 and activin A are independently associated with cardiovascular events and mortality in type 2 diabetes: the prospective Asker and Baerum Cardiovascular Diabetes (ABCD) cohort study. Cardiovasc Diabetol. 2013;12(1):126.
   PubMed Web of Science ®Google Scholar
• Herder C, Schöttker B, Rothenbacher D, et al. Interleukin-6 in the prediction of primary cardiovascular events in diabetes patients: results from the ESTHER study. Atherosclerosis. 2011;216(1):244–247.
   PubMed Web of Science ®Google Scholar
• Soinio M, Marniemi J, Laakso M, et al. High-sensitivity C-reactive protein and coronary heart disease mortality in patients with type 2 diabetes: a 7-year follow-up study. Diabetes Care. 2006;29(2):329–333.
   PubMed Web of Science ®Google Scholar
• Minihane AM, Vinoy S, Russell WR, et al. Low-grade inflammation, diet composition and health: current research evidence and its translation. Br J Nutr. 2015;114(7):999–1012.
   PubMed Web of Science ®Google Scholar
• Lyngbaek S, Andersson C, Marott JL, et al. Soluble urokinase plasminogen activator receptor for risk prediction in patients admitted with acute chest pain. Clin Chem. 2013;59(11):1621–1629.
   PubMed Web of Science ®Google Scholar
• Eapen DJ, Manocha P, Ghasemzadeh N, et al. Soluble urokinase plasminogen activator receptor level is an independent predictor of the presence and severity of coronary artery disease and of future adverse events. J Am Heart Assoc. 2014;3:1–8.
   Web of Science ®Google Scholar
• Lyngbaek S, Sehestedt T, Marott JL, et al. CRP and suPAR are differently related to anthropometry and subclinical organ damage. Int J Cardiol. 2013;167(3):781–785.
   PubMed Web of Science ®Google Scholar
• Haupt TH, Rasmussen LJH, Kallemose T, et al. Healthy lifestyles reduce suPAR and mortality in a Danish general population study. Immun Ageing. 2019;16(1):1–12.
   PubMed Web of Science ®Google Scholar
• Rasmussen LJH, Ladelund S, Haupt TH, et al. Combining national early warning score with soluble urokinase plasminogen activator receptor (suPAR) improves risk prediction in acute medical patients: a registry-based cohort study. Crit Care Med. 2018;46(12):1961–1968.
   PubMed Web of Science ®Google Scholar
• Rotbain Curovic V, Theilade S, Winther SA, et al. Soluble urokinase plasminogen activator receptor predicts cardiovascular events, kidney function decline, and mortality in patients with type 1 diabetes. Diabetes Care. 2019;42(6):1112–1119.
   PubMed Web of Science ®Google Scholar
• Skytte MJ, Samkani A, Petersen AD, et al. A carbohydrate-reduced high-protein diet improves HbA1c and liver fat content in weight stable participants with type 2 diabetes: a randomised controlled trial. Diabetologia. 2019;62(11):2066–2078.
   PubMed Web of Science ®Google Scholar
• Rasmussen ST, Andersen JT, Nielsen TK, et al. Simvastatin and oxidative stress in humans: a randomized, double-blinded, placebo-controlled clinical trial. Redox Biol. 2016;9:32–38.
   PubMed Web of Science ®Google Scholar
• R Core Team. R: a language and environment for statistical computing. Vienna (Austria): R Foundation for Statistical Computing; 2016. URL https://www.R-project.org/.
   Google Scholar
• Vetrani C, Costabile G, Di Marino L, et al. Nutrition and oxidative stress: a systematic review of human studies. Int J Food Sci Nutr. 2013;64(3):312–326.
   PubMed Web of Science ®Google Scholar
• Liu X, Gan W, Zou Y, et al. Elevated levels of urinary markers of oxidative DNA and RNA damage in type 2 diabetes with complications. Oxid Med Cell Longev. 2016;2016:1–7.
   Web of Science ®Google Scholar
• Broedbaek K, Køster-Rasmussen R, Siersma V, et al. Urinary albumin and 8-oxo-7, 8-dihydroguanosine as markers of mortality and cardiovascular disease during 19 years after diagnosis of type 2 diabetes – a comparative study of two markers to identify high risk patients. Redox Biol. 2017;13:363–369.
   PubMed Web of Science ®Google Scholar
• Sivitz WI, Yorek MA. Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities. Antioxid Redox Signal. 2010;12(4):537–577.
   PubMed Web of Science ®Google Scholar
• Poulsen HE, Specht E, Broedbaek K, et al. RNA modifications by oxidation: a novel disease mechanism? Free Radic Biol Med. 2012;52(8):1353–1361.
   PubMed Web of Science ®Google Scholar
• Tanaka M, Chock PB, Stadtman ER. Oxidized messenger RNA induces translation errors. Proc Natl Acad Sci. 2007;104(1):66–71.
   PubMed Web of Science ®Google Scholar
• Houten SM, Wanders R. A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation. J Inherit Metab Dis. 2010;33(5):469–477.
   PubMed Web of Science ®Google Scholar
• Bonora M, Patergnani S, Rimessi A, et al. ATP synthesis and storage. Purinergic Signal. 2012;8(3):343–357.
   PubMed Web of Science ®Google Scholar
• Valavanidis A, Vlachogianni T, Fiotakis C. 8-hydroxy-2′-deoxyguanosine (8-OHdG): a critical biomarker of oxidative stress and carcinogenesis. J Environ Sci Health Part C Environ Carcinog Ecotoxicol Rev. 2009;27(2):120–139.
   PubMed Web of Science ®Google Scholar
• Loft S, Svoboda P, Kasai H, et al. Prospective study of 8-oxo-7,8-dihydro-2’-deoxyguanosine excretion and the risk of lung cancer. Carcinogenesis. 2006;27(6):1245–1250.
   PubMed Web of Science ®Google Scholar
• Loft S, Olsen A, Møller P, et al. Association between 8-oxo-7,8-dihydro-2’-deoxyguanosine excretion and risk of postmenopausal breast cancer: nested case-control study. Cancer Epidemiol Biomarkers Prev. 2013;22(7):1289–1296.
   PubMed Web of Science ®Google Scholar
• Huai Q, Mazar AP, Kuo A, et al. Structure of human urokinase plasminogen activator in complex with its receptor. Science. 2006;311(5761):656–659.
   PubMed Web of Science ®Google Scholar
• Eugen-Olsen J, Andersen O, Linneberg A, et al. Circulating soluble urokinase plasminogen activator receptor predicts cancer, cardiovascular disease, diabetes and mortality in the general population. J Intern Med. 2010;268(3):296–308.
   PubMed Web of Science ®Google Scholar
• Gustafsson A, Ljunggren L, Bodelsson M, et al. The prognostic value of suPAR compared to other inflammatory markers in patients with severe sepsis. Biomark Insights. 2012;7:39–44.
   PubMedGoogle Scholar
• Koch A, Voigt S, Kruschinski C, et al. Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients. Crit Care. 2011;15(1):R63–14.
   PubMed Web of Science ®Google Scholar
• Duncan BB, Schmidt MI, Pankow JS, et al. Low-grade systemic inflammation and the development of type 2 diabetes. Diabetes. 2003;52(7):1799–1805.
   PubMed Web of Science ®Google Scholar
• Ferrari R. The role of TNF in cardiovascular disease. Pharmacol Res. 1999;40(2):97–105.
   PubMed Web of Science ®Google Scholar
• Nordestgaard BG. Does elevated C-reactive protein cause human atherothrombosis? Novel insights from genetics, intervention trials, and elsewhere. Curr Opin Lipidol. 2009;20(5):393–401.
   PubMed Web of Science ®Google Scholar
• Moran LJ, Noakes M, Clifton PM, et al. Short-term meal replacements followed by dietary macronutrient restriction enhance weight loss in polycystic ovary syndrome. Am J Clin Nutr. 2006;84(1):77–87.
   PubMed Web of Science ®Google Scholar
• Weimann A, Broedbaek K, Henriksen T, et al. Assays for urinary biomarkers of oxidatively damaged nucleic acids. Free Radic Res. 2012;46(4):531–540.
   PubMed Web of Science ®Google Scholar