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Original Articles

Identification of a new hemoglobin variant Hb Liuzhou [HBA1:C.182A→G] by MALDI-TOF mass spectrometry during HbA1c measurement

ORCID Icon, , &
Pages 479-483 | Received 26 Apr 2020, Accepted 14 Jun 2020, Published online: 28 Jun 2020

References

  • Patrinos GP, Giardine B, Riemer C, et al. Improvements in the HbVar database of human hemoglobin variants and thalassemia mutations for population and sequence variation studies. Nucleic Acids Res. 2004;32(Database issue):D537–D541.
  • Huisman TH. Combinations of beta chain abnormal hemoglobins with each other or with beta-thalassemia determinants with known mutations: influence on phenotype. Clin Chem. 1997;43(10):1850–1856.
  • Clarke GM, Higgins TN. Laboratory investigation of hemoglobinopathies and thalassemias: review and update. Clin Chem. 2000;46(8 Pt 2):1284–1290.
  • Klingenberg O, Furuset T, Hestbråten CR, et al. HbA1c analysis by capillary electrophoresis - comparison with chromatography and an immunological method. Scand J Clin Lab Invest. 2017;77(6):458–464.
  • Strickland SW, Campbell ST, Little RR, et al. Prevalence of rare hemoglobin variants identified during measurements of Hb A1c by capillary electrophoresis. Clin Chem. 2017;63(12):1901–1902.
  • Little RR, La'ulu SL, Hanson SE, et al. Effects of 49 different rare Hb variants on HbA1c measurement in eight methods. J Diabetes Sci Technol. 2015;9(4):849–856.
  • Xu A, Chen W, Xia Y, et al. Effects of common hemoglobin variants on HbA1c measurements in China: results for α- and β-globin variants measured by six methods. Clin Chem Lab Med. 2018;56(8):1353–1361.
  • Zurbriggen K, Schmugge M, Schmid M, et al. Analysis of minor hemoglobins by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Clin Chem. 2005;51(6):989–996.
  • Xu A, Wang Y, Li J, et al. Evaluation of MALDI-TOF MS for the measurement of glycated hemoglobin. Clin Chim Acta. 2019;498:154–160.
  • Xu A, Lei J, Li J, et al. Falsely high HbA1c value due to a novel α1-globin gene mutation: Hb Shantou [α127(H10)Lys > Glu; HBA1: c.382 A > G]. Scand J Clin Lab Invest. 2018;78(7-8):621–625.
  • Little RR, Rohlfing CL, Hanson S, et al. Effects of hemoglobin (Hb) E and HbD traits on measurements of glycated Hb (HbA1c) by 23 methods. Clin Chem. 2008;54(8):1277–1282.
  • Roberts NB, Amara AB, Morris M, et al. Long-term evaluation of electrospray ionization mass spectrometric analysis of glycated hemoglobin. Clin Chem. 2001;47(2):316–321.
  • Hattan SJ, Parker KC, Vestal ML, et al. Analysis and quantitation of glycated hemoglobin by matrix assisted laser desorption/ionization time of flight mass spectrometry. J Am Soc Mass Spectrom. 2016;27(3):532–541.
  • Kleinert P, Schmid M, Zurbriggen K, et al. Mass spectrometry: a tool for enhanced detection of hemoglobin variants. Clin Chem. 2008;54(1):69–76.
  • Moradkhani K, Préhu C, Old J, et al. Mutations in the paralogous human alpha-globin genes yielding identical hemoglobin variants. Ann Hematol. 2009;88(6):535–543.

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