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Scandinavian Journal of Clinical and Laboratory Investigation Volume 81, 2021 - Issue 4
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Original Articles

Development and validation of a laboratory-based risk score to predict the occurrence of critical illness in hospitalized patients with COVID-19

Salomon Martina Laboratory Medicine Department, Virgen Macarena University Hospital, Seville, Spain; View further author information
,
Sandra Fuentesa Laboratory Medicine Department, Virgen Macarena University Hospital, Seville, Spain; View further author information
,
Catalina Sancheza Laboratory Medicine Department, Virgen Macarena University Hospital, Seville, Spain; View further author information
,
Marta Jimeneza Laboratory Medicine Department, Virgen Macarena University Hospital, Seville, Spain; View further author information
,
Carmen Navarrob Emergency Department, Virgen Macarena University Hospital, Seville, Spain; View further author information
,
Helena Perezc Intensive Care Unit, Virgen Macarena University Hospital, Seville, Spain; View further author information
,
Elena Salamancad Clinical Unit of Infectious Diseases, Clinical Microbiology and Preventive Medicine, Virgen Macarena University Hospital, Seville, Spain; View further author information
,
Jose D. Santotoribioe Laboratory Medicine Department, Virgen del Rocio University Hospital, Seville, Spain; View further author information
,
Joaquín Bobillof Laboratory Medicine Department, Virgen Valme University Hospital, Seville, Spain; View further author information
,
Jose A. Girong Clinical Unit of Internal Medicine, Virgen Macarena University Hospital, Seville, SpainView further author information
,
Javier Gonzalezc Intensive Care Unit, Virgen Macarena University Hospital, Seville, Spain; View further author information
,
Jose M. Garridob Emergency Department, Virgen Macarena University Hospital, Seville, Spain; View further author information
,
Julia Liroa Laboratory Medicine Department, Virgen Macarena University Hospital, Seville, Spain; View further author information
,
Juan M. Guerreroe Laboratory Medicine Department, Virgen del Rocio University Hospital, Seville, Spain; View further author information
,
Maria Cristina Sanchez-Pozof Laboratory Medicine Department, Virgen Valme University Hospital, Seville, Spain; View further author information
,
Victor Sanchez-Margaleta Laboratory Medicine Department, Virgen Macarena University Hospital, Seville, Spain; View further author information
&
Antonio Leon-Justela Laboratory Medicine Department, Virgen Macarena University Hospital, Seville, Spain; Correspondence[email protected]
View further author information
 show all
Pages 282-289 | Received 20 Aug 2020, Accepted 01 Nov 2020, Published online: 11 May 2021

References

  • Lu D. The hunt to find the coronavirus pandemic’s patient zero. New Sci. 2020;245:9.
  • Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054–1062.
  • Rodríguez A, Moreno G, Gómez J, et al. Severe infection due to the SARS-CoV-2 coronavirus: experience of a tertiary hospital with COVID-19 patients during the 2020 pandemic. Med Intensiva. 2020.
  • Bialek S, Boundy E, Bowen V, et al.; CDC COVID-19 Response Team. Severe outcomes among patients with coronavirus disease 2019 (COVID-19) – United States, February 12–March 16, 2020. MMWR Morb Mortal Wkly Rep. 2020;69:343–346.
  • Liang W, Liang H, Ou L, et al.; China Medical Treatment Expert Group for COVID-19. Development and validation of a clinical risk score to predict the occurrence of critical illness in hospitalized patients with COVID-19. JAMA Intern Med. 2020;180:1081–1089.
  • Atri D, Siddiqi HK, Lang JP, et al. COVID-19 for the cardiologist: basic virology, epidemiology, cardiac manifestations, and potential therapeutic strategies. JACC Basic Transl Sci. 2020;5:518–536.
  • Zheng Y, Zhang Y, Chi H, et al. The hemocyte counts as a potential biomarker for predicting disease progression in COVID-19: a retrospective study. Clin Chem Lab Med. 2020;58:1106–1115.
  • Bohn MK, Lippi G, Horvath A, et al. Molecular, serological, and biochemical diagnosis and monitoring of COVID-19: IFCC taskforce evaluation of the latest evidence. Clin Chem Lab Med. 2020;58:1037–1052.
  • Yun H, Sun Z, Wu J, et al. Laboratory data analysis of novel coronavirus (COVID-19) screening in 2510 patients. Clin. Chim. Acta. 2020;507:94–97.
  • Lippi G, Plebani M. The critical role of laboratory medicine during coronavirus disease 2019 (COVID-19) and other viral outbreaks. Clin Chem Lab Med. 2020;58:1063–1069.
  • Collins GS, Reitsma JB, Altman DG, et al. Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD). Ann Intern Med. 2015;162:735–736.
  • Guan W, Ni Z, Hu Y, et al.; China Medical Treatment Expert Group for Covid-19. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382:1708–1720.
  • Steyerberg EW, Harrell FE Jr, Borsboom GJ, et al. Internal validation of predictive models: efficiency of some procedures for logistic regression analysis. J Clin Epidemiol. 2001;54:774–781.
  • Epidemiology Working Group for NCIP Epidemic Response, Chinese Center for Disease Control and Prevention. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China. Zhonghua Liu Xing Bing Xue Za Zhi. 2020;41:145–151.
  • Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323:1061–1069.
  • Henry BM, de Oliveira MHS, Benoit S, et al. Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis. Clin Chem Lab Med. 2020;58:1021–1028.
  • Bonetti G, Manelli F, Patroni A, et al. Laboratory predictors of death from coronavirus disease 2019 (COVID-19) in the area of Valcamonica, Italy. Clin Chem Lab Med. 2020;58:1100–1105.
  • Wynants L, Van Calster B, Collins GS, et al. Prediction models for diagnosis and prognosis of Covid-19: systematic review and critical appraisal. Bmj. 2020;369:m1328.
  • Lu J, Hu S, Fan R, et al. ACP risk grade: a simple mortality index for patients with confirmed or suspected severe acute respiratory syndrome coronavirus 2 disease (COVID-19) during the early stage of outbreak in Wuhan, China. medRxiv Preprint. 2020.
  • Sahu BR, Kishor R, Padhi A, et al. C-reactive protein: a promising biomarker for poor prognosis in COVID-19 infection. Clin Chim Acta. 2020;509:91–94.
  • Mehra MR, Desai SS, Kuy SR, et al. Cardiovascular disease, drug therapy, and mortality in COVID-19. N Engl J Med. 2020;382:e102.
  • Gong J, Ou J, Qiu X, et al. A tool for early prediction of severe coronavirus disease 2019 (COVID-19): a multicenter study using the risk nomogram in Wuhan and Guangdong, China. Clin Infect Dis. 2020;71:833–840.
  • Wang Z, Weng J, Li Z, et al. Development and validation of a diagnostic nomogram to predict covid-19 pneumonia. MedRxiv. Preprint. 2020.

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