Platelet function assessed by ROTEM^®platelet in patients receiving antiplatelet therapy during cardiac and vascular surgery

References

• Sousa-Uva M, Head SJ, Milojevic M, et al. The 2017 EACTS guidelines on perioperative medication in adult cardiac surgery and patient blood management. Eur J Cardiothorac Surg. 2018;53(1):1–33.
   PubMed Web of Science ®Google Scholar
• Engelter S, Lyrer P. Antiplatelet therapy for preventing stroke and other vascular events after carotid endarterectomy. Cochrane Database Syst Rev. 2003;2003(3):Cd001458.
   PubMedGoogle Scholar
• Ranucci M, Baryshnikova E, Castelvecchio S, et al. Major bleeding, transfusions, and anemia: the deadly triad of cardiac surgery. Ann Thorac Surg. 2013;96(2):478–485.
   PubMed Web of Science ®Google Scholar
• Ternstrom L, Hyllner M, Backlund E, et al. A structured blood conservation programme reduces transfusions and costs in cardiac surgery. Interact CardioVasc Thorac Surg. 2014;19(5):788–794.
   PubMed Web of Science ®Google Scholar
• Dyke C, Aronson S, Dietrich W, et al. Universal definition of perioperative bleeding in adult cardiac surgery. J Thorac Cardiovasc Surg. 2014;147(5):1458–1463.e1.
   PubMed Web of Science ®Google Scholar
• Mehta RH, Sheng S, O’Brien SM, et al. Reoperation for bleeding in patients undergoing coronary artery bypass surgery: incidence, risk factors, time trends, and outcomes. Circ Cardiovasc Qual Outcomes. 2009;2(6):583–590.
   PubMed Web of Science ®Google Scholar
• Ferraris VA, Ferraris SP, Saha SP, et al. Perioperative blood transfusion and blood conservation in cardiac surgery: the society of thoracic surgeons and the society of cardiovascular anesthesiologists clinical practice guideline. Ann Thorac Surg. 2007;83(5):S27–S86.
   PubMed Web of Science ®Google Scholar
• Hillis LD, Smith PK, Anderson JL, et al. 2011 ACCF/AHA guideline for coronary artery bypass graft surgery: executive summary: a report of the American college of cardiology foundation/American heart association task force on practice guidelines. J Thorac Cardiovasc Surg. 2012;143(1):4–34.
   PubMed Web of Science ®Google Scholar
• Hale B, Pan W, Misselbeck TS, et al. Combined clopidogrel and aspirin therapy in patients undergoing carotid endarterectomy is associated with an increased risk of postoperative bleeding. Vascular 2013;21(4):197–204.
   PubMed Web of Science ®Google Scholar
• Jones DW, Goodney PP, Conrad MF, et al. Dual antiplatelet therapy reduces stroke but increases bleeding at the time of carotid endarterectomy. J Vasc Surg. 2016;63(5):1262–1270.e3.
   PubMed Web of Science ®Google Scholar
• Batchelder A, Hunter J, Cairns V, et al. Dual antiplatelet therapy prior to expedited carotid surgery reduces recurrent events prior to surgery without significantly increasing peri-operative bleeding complications. Eur J Vasc Endovasc Surg. 2015;50(4):412–419.
   PubMed Web of Science ®Google Scholar
• Payne DA, Jones CI, Hayes PD, et al. Beneficial effects of clopidogrel combined with aspirin in reducing cerebral emboli in patients undergoing carotid endarterectomy. Circulation 2004;109(12):1476–1481.
   PubMed Web of Science ®Google Scholar
• Naylor AR. Medical treatment strategies to reduce perioperative morbidity and mortality after carotid surgery. Semin Vasc Surg. 2017;30(1):17–24.
   PubMed Web of Science ®Google Scholar
• Sharpe RY, Dennis MJ, Nasim A, et al. Dual antiplatelet therapy prior to carotid endarterectomy reduces post-operative embolisation and thromboembolic events: post-operative transcranial doppler monitoring is now unnecessary. Eur J Vasc Endovasc Surg. 2010;40(2):162–167.
   PubMed Web of Science ®Google Scholar
• Naylor AR, Ricco JB, de Borst GJ, et al. Editor’s choice - management of atherosclerotic carotid and vertebral artery disease: 2017 clinical practice guidelines of the European Society for vascular surgery (ESVS). Eur J Vasc Endovasc Surg. 2018;55(1):3–81.
   PubMed Web of Science ®Google Scholar
• Levine M, Swenson S, McCormick T, et al. Reversal of thienopyridine-induced platelet dysfunction following desmopressin administration. J Med Toxicol. 2013;9(2):139–143.
   PubMedGoogle Scholar
• Hanke AA, Dellweg C, Kienbaum P, et al. Effects of desmopressin on platelet function under conditions of hypothermia and acidosis: an in vitro study using multiple electrode aggregometry*. Anaesthesia 2010;65(7):688–691.
   PubMed Web of Science ®Google Scholar
• Desborough MJ, Oakland KA, Landoni G, et al. Desmopressin for treatment of platelet dysfunction and reversal of antiplatelet agents: a systematic review and meta-analysis of randomized controlled trials. J Thromb Haemost. 2017;15(2):263–272.
   PubMed Web of Science ®Google Scholar
• Andersen LK, Hvas AM, Hvas CL. Effect of desmopressin on platelet dysfunction during antiplatelet therapy: a systematic review. Neurocrit Care. 2021;34(3):1026–1046.
   PubMed Web of Science ®Google Scholar
• Swieringa F, Lancé MD, Fuchs B, et al. Desmopressin treatment improves platelet function under flow in patients with postoperative bleeding. J Thromb Haemost. 2015;13(8):1503–1513.
   PubMed Web of Science ®Google Scholar
• Weber CF, Dietrich W, Spannagl M, et al. A point-of-care assessment of the effects of desmopressin on impaired platelet function using multiple electrode whole-blood aggregometry in patients after cardiac surgery. Anesth Analg. 2010;110(3):702–707.
   PubMed Web of Science ®Google Scholar
• Salzman EW, Weinstein MJ, Weintraub RM, et al. Treatment with desmopressin acetate to reduce blood loss after cardiac surgery. A double-blind randomized trial. N Engl J Med. 1986;314(22):1402–1406.
   PubMed Web of Science ®Google Scholar
• Despotis GJ, Levine V, Saleem R, et al. Use of point-of-care test in identification of patients who can benefit from desmopressin during cardiac surgery: a randomised controlled trial. Lancet 1999;354(9173):106–110.
   PubMed Web of Science ®Google Scholar
• Rocha E, Llorens R, Páramo JA, et al. Does desmopressin acetate reduce blood loss after surgery in patients on cardiopulmonary bypass? Circulation 1988;77(6):1319–1323.
   PubMed Web of Science ®Google Scholar
• Wademan BH, Galvin SD. Desmopressin for reducing postoperative blood loss and transfusion requirements following cardiac surgery in adults. Interact Cardiovasc Thorac Surg. 2014;18(3):360–370.
   PubMed Web of Science ®Google Scholar
• Mirmansoori A, Farzi F, Sedighinejad A, et al. The effect of desmopressin on the amount of bleeding in patients undergoing coronary artery bypass graft surgery with a cardiopulmonary bypass pump after taking anti-Platelet medicine. Anesth Pain Med. 2016;6(5):e39226.
   PubMedGoogle Scholar
• de Prost D, Barbier-Boehm G, Hazebroucq J, et al. Desmopressin has no beneficial effect on excessive postoperative bleeding or blood product requirements associated with cardiopulmonary bypass. Thromb Haemost. 1992;68(2):106–110.
   PubMed Web of Science ®Google Scholar
• Hedderich GS, Petsikas DJ, Cooper BA, et al. Desmopressin acetate in uncomplicated coronary artery bypass surgery: a prospective randomized clinical trial. Can J Surg. 1990;33(1):33–36.
   PubMed Web of Science ®Google Scholar
• Temeck BK, Bachenheimer LC, Katz NM, et al. Desmopressin acetate in cardiac surgery: a double-blind, randomized study. South Med J. 1994;87(6):611–615.
   PubMed Web of Science ®Google Scholar
• Pleym H, Stenseth R, Wahba A, et al. Prophylactic treatment with desmopressin does not reduce postoperative bleeding after coronary surgery in patients treated with aspirin before surgery. Anesth Analg. 2004;98(3):578–584.
   PubMed Web of Science ®Google Scholar
• Desborough MJ, Oakland K, Brierley C, et al. Desmopressin use for minimising perioperative blood transfusion. Cochrane Database Syst Rev. 2017;7(7):Cd001884.
   PubMed Web of Science ®Google Scholar
• Ghadimi K, Levy JH, Welsby IJ. Perioperative management of the bleeding patient. Br J Anaesth. 2016;117(3):iii18–iii30.
   PubMed Web of Science ®Google Scholar
• Cattaneo M. The use of desmopressin in open-heart surgery. Haemophilia 2008;14(1):40–47.
   PubMed Web of Science ®Google Scholar
• Leithäuser B, Zielske D, Seyfert UT, et al. Effects of desmopressin on platelet membrane glycoproteins and platelet aggregation in volunteers on clopidogrel. Clin Hemorheol Microcirc. 2008;39(1–4):293–302.
   PubMed Web of Science ®Google Scholar
• Ranucci M, Nano G, Pazzaglia A, et al. Platelet mapping and desmopressin reversal of platelet inhibition during emergency carotid endarterectomy. J Cardiothorac Vasc Anesth. 2007;21(6):851–854.
   PubMed Web of Science ®Google Scholar
• Holck MH, Christensen TD, Hvas AM. Influence of selected antithrombotic treatment on thromboelastometric results. Scand J Clin Lab Invest. 2018;78(1–2):11–17.
   PubMed Web of Science ®Google Scholar
• Hvas AM, Favaloro EJ. Platelet function analyzed by light transmission aggregometry. Methods Mol Biol. 2017;1646:321–331.
   PubMedGoogle Scholar
• Benedek IH, Joshi AS, Pieniaszek HJ, et al. Variability in the pharmacokinetics and pharmacodynamics of low dose aspirin in healthy male volunteers. J Clin Pharmacol. 1995;35(12):1181–1186.
   PubMed Web of Science ®Google Scholar
• Karaźniewicz-Łada M, Danielak D, Burchardt P, et al. Clinical pharmacokinetics of clopidogrel and its metabolites in patients with cardiovascular diseases. Clin Pharmacokinet. 2014;53(2):155–164.
   PubMed Web of Science ®Google Scholar
• Sibbing D, Braun S, Jawansky S, et al. Assessment of ADP-induced platelet aggregation with light transmission aggregometry and multiple electrode platelet aggregometry before and after clopidogrel treatment. Thromb Haemost. 2008;99(01):121–126.
   PubMed Web of Science ®Google Scholar
• Bouman HJ, Parlak E, van Werkum JW, et al. Which platelet function test is suitable to monitor clopidogrel responsiveness? A pharmacokinetic analysis on the active metabolite of clopidogrel. J Thromb Haemost. 2010;8(3):482–428.
   PubMed Web of Science ®Google Scholar
• Nissen PH, Skipper MT, Hvas AM. Whole blood platelet aggregation determined by the ROTEM platelet equipment; reference intervals and stability. Platelets 2020;31(2):215–220.
   PubMed Web of Science ®Google Scholar
• Petricevic M, Konosic S, Biocina B, et al. Bleeding risk assessment in patients undergoing elective cardiac surgery using ROTEM(®) platelet and Multiplate(®) impedance aggregometry. Anaesthesia 2016;71(6):636–647.
   PubMed Web of Science ®Google Scholar
• Banga PV, Varga A, Csobay-Novák C, et al. Incomplete circle of Willis is associated with a higher incidence of neurologic events during carotid eversion endarterectomy without shunting. J Vasc Surg. 2018;68(6):1764–1771.
   PubMed Web of Science ®Google Scholar
• Lopes CT, Brunori EF, Cavalcante AM, et al. Factors associated with excessive bleeding after cardiac surgery: a prospective cohort study. Heart Lung. 2016;45(1):64–69.e2.
   PubMed Web of Science ®Google Scholar
• Kjellberg G, Holm M, Lindvall G, et al. Platelet function analysed by ROTEM platelet in cardiac surgery after cardiopulmonary bypass and platelet transfusion. Transfus Med. 2020;30:369–376.
   PubMed Web of Science ®Google Scholar
• Höfer J, Fries D, Solomon C, et al. A snapshot of coagulopathy after cardiopulmonary bypass. Clin Appl Thromb Hemost. 2016;22(6):505–511.
   PubMed Web of Science ®Google Scholar
• Chechik O, Goldstein Y, Behrbalk E, et al. Blood loss and complications following carotid endarterectomy in patients treated with clopidogrel. Vascular 2012;20(4):193–197. Aug
   PubMed Web of Science ®Google Scholar
• Rosenbaum A, Rizvi AZ, Alden PB, et al. Outcomes related to antiplatelet or anticoagulation use in patients undergoing carotid endarterectomy. Ann Vasc Surg. 2011;25(1):25–31.
   PubMed Web of Science ®Google Scholar
• Ranucci M, Pistuddi V, Di Dedda U, et al. Platelet function after cardiac surgery and its association with severe postoperative bleeding: the PLATFORM study. Platelets 2019;30(7):908–914.
   PubMed Web of Science ®Google Scholar
• Lethagen S. Desmopressin (DDAVP) and hemostasis. Ann Hematol. 1994;69(4):173–180.
   PubMed Web of Science ®Google Scholar
• Svensson PJ, Bergqvist PB, Juul KV, et al. Desmopressin in treatment of haematological disorders and in prevention of surgical bleeding. Blood Rev. 2014;28(3):95–102.
   PubMed Web of Science ®Google Scholar
• Pearson K, Jensen H, Kander T, et al. Desmopressin in vitro effects on platelet function, monitored with multiplate, ROTEM and sonoclot. Scand J Clin Lab Invest. 2016;76(4):282–290. Jul
   PubMed Web of Science ®Google Scholar
• Schultz-Lebahn A, Skipper MT, Hvas AM, et al. Optimized tool for evaluation of platelet function measured by impedance aggregometry. Platelets 2021;32(6):842–844.
   PubMed Web of Science ®Google Scholar
• Wurtz M, Hvas AM, Kristensen SD, et al. Platelet aggregation is dependent on platelet count in patients with coronary artery disease. Thromb Res. 2012;129(1):56–61.
   PubMed Web of Science ®Google Scholar
• Tiedemann Skipper M, Rubak P, Halfdan Larsen O, et al. Thrombocytopenia model with minimal manipulation of blood cells allowing whole blood assessment of platelet function. Platelets 2016;27(4):295–300.
   PubMed Web of Science ®Google Scholar
• Ranucci M, Baryshnikova EFTS. Clinical outcome research score G. The interaction between preoperative platelet count and function and its relationship with postoperative bleeding in cardiac surgery. Platelets 2017;28(8):794–798.
   PubMed Web of Science ®Google Scholar
• Skjelbakken T, Langbakk B, Dahl IM, et al. Haemoglobin and anaemia in a gender perspective: the tromsø study. Eur J Haematol. 2005;74(5):381–388.
   PubMed Web of Science ®Google Scholar
• Jennings LK, Watson S. Massive transfusion. StatPearls. Treasure Island (FL): StatPearls Publishing; 2020.
   Google Scholar