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Research Articles

Validation of an indirect ELISA assay for assessment of autoantibodies against full-length TRIM21 and its individual domains

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Pages 309-317 | Received 11 Aug 2022, Accepted 29 May 2023, Published online: 28 Jun 2023

References

  • Brito-Zerón P, Baldini C, Bootsma H, et al. Sjögren syndrome. Nat Rev Dis Primers. 2016;72:16047. doi: 10.1038/nrdp.2016.47.
  • Yoshimi R, Ueda A, Ozato K, et al. Clinical and pathological roles of Ro/SSA autoantibody system. Clin Dev Immunol. 2012;2012:606195. doi: 10.1155/2012/606195.
  • Fayyaz A, Kurien BT, Scofield RH. Autoantibodies in Sjögren’s syndrome. Rheum Dis Clin North Am. 2016;42(3):419–434. doi: 10.1016/j.rdc.2016.03.002.
  • Jones EL, Laidlaw SM, Dustin LB. TRIM21/Ro52 – roles in innate immunity and autoimmune disease. Front Immunol. 2021;12:738473. doi: 10.3389/fimmu.2021.738473.
  • Rivera TL, Izmirly PM, Birnbaum BK, et al. Disease progression in mothers of children enrolled in the research registry for neonatal lupus. Ann Rheum Dis. 2009;68(6):828–835. doi: 10.1136/ard.2008.088054.
  • Lazzerini PE, Capecchi PL, Laghi-Pasini F, et al. Autoimmune channelopathies as a novel mechanism in cardiac arrhythmias. Nat Rev Cardiol. 2017;14(9):521–535. doi: 10.1038/nrcardio.2017.61.
  • Szczerba BM, Kaplonek P, Wolska N, et al. Interaction between innate immunity and Ro52-induced antibody causes Sjögren’s syndrome-like disorder in mice. Ann Rheum Dis. 2016;75(3):617–622. doi: 10.1136/annrheumdis-2014-206297.
  • Foss S, Bottermann M, Jonsson A, et al. TRIM21-From intracellular immunity to therapy. Front Immunol. 2019;10:2049. doi: 10.3389/fimmu.2019.02049.
  • McEwan WA, James LC. TRIM21-dependent intracellular antibody neutralization of virus infection. Prog Mol Biol Transl Sci. 2015;129:167–187.
  • Infantino M, Meacci F, Grossi V, et al. Serological epitope profile of anti-Ro52-positive patients with systemic autoimmune rheumatic diseases. Arthritis Res Ther. 2015;17:365. doi: 10.1186/s13075-015-0871-3.
  • Ambrosi A, Dzikaite V, Park J, et al. Anti-Ro52 monoclonal antibodies specific for amino acid 200-239, but not other Ro52 epitopes, induce congenital heart block in a rat model. Ann Rheum Dis. 2012;71(3):448–454. doi: 10.1136/annrheumdis-2011-200414.
  • Jumper J, Evans R, Pritzel A, et al. Highly accurate protein structure prediction with AlphaFold. Nature. 2021;596(7873):583–589. doi: 10.1038/s41586-021-03819-2.
  • Varadi M, Anyango S, Deshpande M, et al. AlphaFold protein structure database: massively expanding the structural coverage of protein-sequence space with high-accuracy models. Nucleic Acids Res. 2022;50(D1):D439–D444. doi: 10.1093/nar/gkab1061.
  • Kragstrup TW, Vorup-Jensen T, Deleuran B, et al. A simple set of validation steps identifies and removes false results in a sandwich enzyme-linked immunosorbent assay caused by anti-animal IgG antibodies in plasma from arthritis patients. Springerplus. 2013;2(1):263–273. doi: 10.1186/2193-1801-2-263.
  • James LC, Keeble AH, Khan Z, et al. Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function. Proc Natl Acad Sci U S A. 2007;104(15):6200–6205. doi: 10.1073/pnas.0609174104.
  • Wolska N, Rybakowska P, Rasmussen A, et al. Brief report: patients with primary Sjögren’s syndrome who are positive for autoantibodies to tripartite motif-containing protein 38 show greater disease severity. Arthritis Rheumatol. 2016;68(3):724–729. doi: 10.1002/art.39497.
  • Sroka M, Bagavant H, Biswas I, et al. Immune response against the coiled coil domain of Sjögren’s syndrome associated autoantigen Ro52 induces salivary gland dysfunction. Clin Exp Rheumatol. 2018;36(Suppl 112(3):41–46.

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