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Original Article

Clinical Chemistry: Vitamin B12 -Binding Proteins in Human Gastric Mucosa General Pattern and Demonstration of Intrinsic Factor Isoproteins Typical of Mucosa

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Pages 5-11 | Received 26 Apr 1974, Accepted 30 Sep 1974, Published online: 28 Aug 2009

References

  • Allen R. H., Mehlman C. Isolation of gastric vitamin B12-binding proteins using affinity chromatography. I. Purification and properties of human intrinsic factor. J. biol. Chem. 1973; 248: 3660
  • Allen R. H., Mehlrnan C. Isolation of gastric vitamin B12-binding proteins using affinity chromatography. 11. Purification and properties of hog intrinsic factor and hog non-intrinsic factor. J. biol. Chem. 1973; 248: 3670
  • Andrews P. The gel-filtration behaviour of proteins related to their molecular weights over a wide range. Biochem. J. 1965; 96: 595
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  • Gottlieb C., Lau K.-S., Wassermann L. R., Herbert V. Rapid charcoal assay for intrinsic factor (IF), gastric juice unsaturated B12 binding capacity, antibody to lF, and serum unsaturated B12 binding capacity. Blood 1965; 25: 875
  • Gdsbeck R. Intrinsic factor and the transcobalamins with reflections on the general function and evolution of soluble transport proteins. Scand. J. clin. Lab. Invest. 1967; 19(Suppl. 95)7
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  • Gräsbeck R., Marcoullis G. Studies on a fraction of human gastric mucosa containing intrinsic factor isoproteins typical of mucosa. Scand. 1. clin. Lab. Invest. 1975; 35: 13
  • Gräsbeck R., Simons K., Sinkkonen I. Purification of intrinsic factor and vitamin B12 binders from human gastric juice. Ann. Med. ex p. Fenn. 1962; 40, Suppl. 6
  • Gräsbeck R., Visuri K., Stenman U.-H. The vitamin BIZ-binding protein in human saliva. Isolation, characterization and comparison with the unpurified protein. Biochim. biophys. Acta (Amst.) 1972; 263: 721
  • Hoedemaeker P. J. Investigations on the site of production of Castle's gastric intrinsic factor. Dissertation, University of Groningen. 1965
  • Hom B. L., Olesen H. Molecular weights of vitamin BIZ binding proteins in human serum determined by Sephadex G-200 gel filtration. Scand. J. din. Lab. Invest. 1967; 19: 269
  • Martin R. G., Ames B. N. A method for determining the sedimentation behaviour of enzymes: application to protein mixtures. 1. biol. Chem. 1961; 236: 1372
  • Wilkinson J. F., Klein L., Ashford C. A. Hemopoietic activity of human stomach in pernicious anaemia. Quart. J. Med. 1938; 1: 555

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