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Original

Effect of myocardial ischaemia and antilipolytic agents on lipolysis and fatty acid metabolism in the in situ dog heart

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Pages 559-568 | Received 08 Aug 1978, Accepted 12 Mar 1979, Published online: 14 Feb 2011

References

  • Berdeaux A., Goutte R., Giudicelli J.-F., Boissier J.-R. Effects of verapamil on regional myocardial blood flow and ST segment. Role of the induced bradycardia. Eur. J. Pharmac. 1976; 39: 287
  • Brownsey R. W., Brundt R. V. The effect of adrenaline-induced endogenous lipolysis upon the mechanical and metabolic performance of ischaemi-cally perfused rat hearts. Clin. Sci. molec. Med. 1977; 53: 513
  • Challoner D. R., Steinberg D. Effect of free fatty acid on the oxygen consumption of perfused rat heart. Am. J. Physiol. 1966; 210: 280
  • Chernick S. S. Determination of glycerol in acyl glycerol. Methods in Enzymology 14, M. Lowenstein. Academic Press, New York 1969; 627
  • Christian D. R., Kilsheimer G. S., Pettett G., Paradise R., Ashmore J. Regulation of lipolysis in cardiac muscle: A system similar to the hormone-sensitive lipase of adipose tissue. Advances in Enzyme Regulation. Pergamon, New York 1969; 71
  • Crass M. F., III, Shipp J. C., Pieper G. M. Effects of catecholamines on myocardial endogenous substrates and contractility. Am. J. Physiol. 1975; 228: 618
  • Evans J. R. Importance of fatty acid in myocardial metabolism. Circulat. Res. 1964; 15: 96
  • Ho R. J. Radiochemical assay of long-chain fatty acids using 63Ni as tracer. Analyt. Biochem. 1970; 36: 105
  • Hough F. S., Gevers W. Catecholamine release as mediator of intracellular enzyme activation in ischaemic perfused rat hearts. S. Afr. med. J. 1975; 49: 538
  • Kessler J. I., Senderoff E. Effect of experimental infarction, manual massage, and electrical defibrillation on myocardial lipo-protein lipase activity of dogs. J. clin. Incest. 1962; 41: 1531
  • Kjekshus J. K., Grøttum P. Modification of acute myocardial infarction by intravenous β-pyridylcarbinol. Acta med. scatul., In press
  • Kjekshus J. K., MjøS O. D. Effect of inhibition of lipolysis on infarct size after experimental coronary artery occlusion. J. clin. Incest. 1973; 52: 1770
  • Kurien V. A., Yates P. A., Oliver M. F. The role of free fatty acids in the production of ventricular arrhythmias after acute coronary artery occlusion. Eur. J. clin. Invest. 1971; I: 225
  • Lassers B. W., Wahlquist M. L., Kaijser L., Carlson L. A. Effect of nicotinic acid on myocardial metabolism in man at rest and during exercise. J. appl. Physiol. 1972; 33: 72
  • Luxton M. R., Miller N. E., Oliver M. F. Anti-polylic therapy in angina pectoris. Reduction of exercise-induced ST segment depression. Br. Heart J. 1976; 38: 1204
  • Maroko P. R., Kjekshus J. K., Sobel B. E., Watanabe T., Covell J. W., Ross J., Braunwald E. Factors influencing infarct size following experimental coronary artery occlusion. Circulation 1971; 43: 67
  • MjøS O. D. Effect of free fatty acids on myocardial function and oxygen consumption in intact dogs. J. clin. Invest. 1971; 50: 1386
  • MjøS O. D. Effect of inhibition of lipolysis on myocardial oxygen consumption in the presence of isoproterenol. J. clin. Invest. 1971; 50: 1869
  • MjøS O. D., Miller N. E., Riemersma R. A., Oliver M. F. Effects of p-chlorophenoxyisobutyrate on myocardial free fatty acid extraction, ventricular blood flow, and epicardial ST-segment elevation during coronary occlusion in dogs. Circulation 1976; 53: 494
  • Most A. S., Brachfeld N., Gorlin R., Wahren J. Free fatty acid metabolism of the human heart at rest. J. clin. Invest. 1969; 48: 1177
  • Oliver M. F. The influence of myocardial metabolism on ischemic damage. Circulation 1976; 53: 168, Suppl. 1
  • Oliver M. F., Kurien V. A., Greenwood T. W. Relation between serum-free fatty acids and arrhythmias and death after acute myocardial infarction. Lancet 1968; i: 710
  • Opie L. H., Owen P., Riemersma R. Relative rates of oxidation of glucose and free fatty acids by ischaemic and non-ischaemic myocardium after coronary artery ligation in the dog. Eur. J. clin. Invest. 1973; 3: 419
  • Opie L. H., Owen P., Thomas M., Samson R. Coronary sinus lactate measurements in the assessment of myocardial ischaemia. Comparison with changes in the ratio lactate/pyruvate and beta-hydroxybutyrate/acetoacetate and with release of hydrogen, phosphate and potassium iones from the heart. Am. J. Cardiol 1973; 32: 295
  • Opie L. H., Tonsey M., Kennelly B. M. Proposed metabolic vicious circle in patients with large myocardial infarcts and high plasma-free fatty acid concentrations. Lancet 1977; ii: 890
  • Owen P., Thomas M., Young V., Opie L. H. Comparison between metabolic changes in local venous and coronary sinus blood after acute experimental coronary arterial occlusion. Am. J. Cardiol. 1970; 25: 562
  • Parratt J. R., Ledingham I. M., McArdle C. S. Effect of a coronary vasodilator drug (carbochro-men) on blood flow and oxygen extraction in acute myocardial infarction. Cardiovasc. Res. 1973; 7: 401
  • Passonneau J. V. L-(+)-lactate. A fluorimetric method. Methods of Enzymatic Analysis2nd edition., H. U. Bergmeyer. Academic Press, London 1974; 1468
  • Riemersma R. A., Talbot R. C., Ungar A., MjøS O. D., Oliver M. F. Effects of prostaglandin -E1on ST segment elevation and regional myocardial blood flow during experimental myocardial ischaemia in dogs. Eur. J. clin. Invest. 1977; 7: 515
  • Russel D. C., Oliver M. F. Effect of antilipolytic therapy on ST segment elevation during myocardial ischaemia in man. Br. Heart J. 1978; 40: 117
  • Robinson J., Newsholm E. A. Glycerol kinase activities in rat heart and adipose tissue. Biochem. J. 1967; 104: 2c
  • Sayen J. J., Sheldon W. F., Peirce G., Kuo P. T. Polarographic oxygen, the epicardial electrocardiogram and muscle contraction in experimental acute regional ischaemia of the left ventricle. Circular. Res. 1958; 6: 779
  • Scheuer J., Brachfeld N. Myocardial uptake and fractional distribution of palmitate-1-C14 by the ischemic dog heart. Metabolism 1966; 15: 945
  • Shahab L., Wollenberger A., Krause E. G., Genz S. The effect of acute ischemia on catecholamines and cyclic AMP levels in normal and hyper-trophied myocardium. Effect of Acute Ischaemia on Myocardial Function, M. F. Oliver, D. G. Julian, K. W. Donald. Churchill Livingstone, Edinburgh and London 1972; 97
  • Shug A. L., Shrago E., Bittar N., Folts J. D., Koke J. R. Acyl-CoA inhibition of adenine nucleotide translocation in ischemic myocardium. Am. J. Physiol. 1975; 228: 689
  • Snedecor G. W., Cochran W. G. Statistical Methods6th ed. The Iowa State University Press, Ames 1967
  • Takenaka F., Takeo S. Effects of isoproterenol on myocardial lipid metabolism in rat hearts perfused with and without exogenous substrate. J. molec. cell. Cardiol. 1976; 8: 925
  • Vik-Mo H. Distribution of coronary blood flow during acute coronary occlusion in dogs. Effect of nicotinic acid and sodium salicylate. Scand. J. clin. Lab. Invest. 1977; 37: 697
  • Vik-Mo H., Mjas O. D. Effects of sodium salicylate and acetylsalicylic acid on epicardial ST-segment elevation during coronary artery occlusion in dogs. Scand. J. clin. Lab. Invest. 1977; 37: 287
  • Vik-Mo H., MjøS O. D. Myocardial metabolism and performance during sodium salicylate infusion in dogs. Scand. J. clin. Lab. Invest. 1976; 36: 763
  • Welman E. Labilization and stabilization of lysosomes in anoxic guinea pig heart. Br. Heart J. 1975; 37: 781
  • Williamson J. R. Metabolic effects of epinephrine in the isolated, perfused rat heart. I. Dissociation of the glycogenolytic from the metabolic stimulatory effect. J. biol. Chem. 1964; 239: 2721

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