Uracil-DNA glycosylase and deoxyuridine triphosphatase: Studies of activity and subcellular location in human normal and malignant lymphocytes

References

• Allen J. R., Reddy G. P.V., Lasser G. W., Mathews C. K. T4 ribunucleotide reductase. Physical and kinetic linkage to other enzymes of deoxyribonucleotide biosynthesis. J. biol. Chem. 1980; 255: 7583
   PubMed Web of Science ®Google Scholar
• Aposhian H. V., Kornberg A. Enzymatic synthesis of deoxyribonucleic acid. IX. The polymerase formed after T2 bacteriophage infection of Escherichia coli: A new enzyme. J. biol. Chem. 1962; 237: 519
   PubMed Web of Science ®Google Scholar
• Bertani L. E., Häggmark A., Reichard P. Enzymatic synthesis of deoxyribonucleotides. II. Formation and interconversion of deoxyuridine phosphates. J. biol. Chem. 1963; 238: 3407
   Google Scholar
• Bessman M. J., Lehman I. R., Adler J., Zimmerman S. B., Simms E. S., Kornberg A. Enzymatic synthesis of deoxyribonucleic acid. III. The incorporation of pyrimidine and purine analogs into deoxyribonucleic acid. Proc. natn. Acad. Sci. U.S.A. 1958; 44: 633
   PubMed Web of Science ®Google Scholar
• Boyum A. Isolation of mononuclear cells and granulocytes from human blood. Scand. J. clin. Lab. Invest. 1968; 21(Suppl. 97)77
   PubMed Web of Science ®Google Scholar
• Caradonna S. J., Cheng Y.-C. The role of deoxyuridine triphosphate nucleotidohydrolase, uracil-DNA glycosylase, and DNA polymerase alpha in the metabolism of FUdR in human tumor cells. Molec. Pharmacol. 1980; 18: 513
   PubMed Web of Science ®Google Scholar
• Chen T. R. In situ detection of mycoplasm contamination in cell cultures by fluorescent Hoechst Compound 33258. Exp. Cell Res. 1977; 104: 255
   PubMed Web of Science ®Google Scholar
• Deutsch W. A., Spiering A. L. A new pathway expressed during a distinct stage of Drosophila development for the removal of dUMP residues in DNA. J. biol. Chem. 1982; 257: 3366
   Google Scholar
• Goulian M., Bleile B., Tseng B. Y. The effect of methotrexate on levels of dUTP in animal cells. J. biol. Chem. 1980; 255: 10630
   PubMed Web of Science ®Google Scholar
• Goulian M., Bleile B., Tseng B. Y. Methotrexate-induced misincorporation of uracil into DNA. Proc. natn. Acad. Sci. U.S.A. 1980; 77: 1956
   PubMed Web of Science ®Google Scholar
• Griffiths P. A., Milson J. P., Lloyd J. B. Plasma acid hydrolases in normal adults and children, and in patients with some lysosomal storage diseases. Clinica chim. Acta. 1978; 90: 129
   PubMed Web of Science ®Google Scholar
• Ingraham H. A., Tseng B. Y., Goulian M. Mechanism for exclusion of 5-fluorouracil from DNA. Cancer Res. 1980; 40: 998
   PubMedGoogle Scholar
• Kelley W. S., Chalmers K., Murrary N. E. Isolation and characterization of a lambda pol A transducing phage. Proc. natn. Acad. Sci. U.S.A. 1977; 74: 5632
   PubMed Web of Science ®Google Scholar
• Kelley W. S., Stump K. H. A rapid procedure for isolation of large quantities of Escherichia coli DNA polymerase I utilizing a lambda pol A transducing phage. J. biol. Chem. 1979; 254: 3206
   Google Scholar
• Koch J., Storstad E. L. Incorporation of [3H] thymidine into nuclear and mitochondrial DNA in synchronized mammalian cells. Eur. J. Biochem. 1967; 3: 1
   Google Scholar
• Labarca C., Paigen K. A simple, rapid, and sensitive DNA assay procedure. Analyt. Biochem. 1980; 102: 344
   PubMed Web of Science ®Google Scholar
• Lindahl T. An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues. Proc. natn. Acad. Sci. U.S.A. 1974; 72: 3649
   Google Scholar
• Lindahl T. DNA glycosylases, endonucleases for apurinic/apyrimidinic sites, and base excision-repair. Progr. Nucl. Acid. Res. Mol. Biol. 1979; 22: 135
   PubMedGoogle Scholar
• Lowry O. H., Rosebrough N. J., Fall A. L., Randall R. J. Protein measurement with Folin Phenol Reagent. J. biol. Chem. 1951; 193: 265
   PubMed Web of Science ®Google Scholar
• Luzzatto L., Falusi A. O., Joju E. A. Uracil in DNA in megaloblastic anemia. N. Engl. J. Med. 1981; 305: 1156
   Google Scholar
• Miyoshi I., Hiraki S., Tsubota T., Kubonishi I., Matsudo Y., Nakayama T., Kishimoto H., Kimura I. Human B cell, T cell and null cell leukaemic cell lines derived from acute lymphoblastic leukaemias. Nature 1977; 267: 843
   PubMed Web of Science ®Google Scholar
• Pellegrino M. A., Ferrone S., Dierich M. P., Reisfeld R. A. Enhancement of sheep red blood cell human lymphocyte rosette formation by the sulfhydryl compound 2-amino ethyl-thiouronium bromide. Clin. Immunol. Immunopathol. 1975; 3: 324
   PubMedGoogle Scholar
• Reddy G. P.V., Pardee A. B. Multienzyme complex for metabolic channeling in mammalian DNA replication. Proc. natn. Acad. Sci. U.S.A. 1980; 77: 3312
   PubMed Web of Science ®Google Scholar
• Reed A. H., Henry R. J. Accuracy, precision and control charts. Clinical Chemistry, R. J. Henry, D. C. Cannon, J. W. Winkleman. Harper & Row Publishers, Hagerstown 1974; 287
   Google Scholar
• Rhodes G., Jentsch K. D., Jovin T. M. A simple and rapid purification method for Escherichia coli DNA polymerase I. J. biol. Chem. 1979; 254: 7465
   Google Scholar
• Sedwick W. D., Kutler M., Brown O. E. Antifolate-induced misincorporation of deoxyuridine monophosphate into DNA: Inhibition of high molecular weight DNA synthesis in human lymphoblastoid cells. Proc. natn. Acad, Sci. U.S.A. 1981; 78: 917
   Google Scholar
• Shlomai J., Kornberg A. Deoxyuridine triphosphatase of Escherichia coli. J. biol. Chem. 1978; 253: 3305
   PubMed Web of Science ®Google Scholar
• Sirover M. A. Induction of the DNA repair enzyme uracil-DNA glycosylase in stimulated human lymphocytes. Cancer Res. 1979; 39: 2090
   PubMedGoogle Scholar
• Taheri M. R., Wickremasinghe R. G., Hoffbrand A. V. Differences in DNA synthesis between lymphoblasts of thymic and non-thymic origin. Br. J. Haemat. 1981; 49: 132
   Google Scholar
• Vilpo J. A. Mitogen induction of deoxyuridine triphosphatase activity in human T and B lymphocytes. Med. Biol. 1983; 61: 54
   Google Scholar
• Yoshida S., Masaki S. Utilization in vitro of deoxyuridine triphosphate in DNA synthesis by DNA polymerases alpha and beta from calf thymus. Biochim. biophys, acta. 1979; 561: 392
   Google Scholar