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Original Article

Reactivity of amniotic fluid alpha-fetoprotein with concanavalin A-sepharose in pre-natal diagnosis of fetal malformations

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Pages 687-690 | Received 02 May 1983, Accepted 14 Jul 1983, Published online: 17 Mar 2010

References

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  • Brock D. J. Spina bifida: Early antenatal diagnosis using amniotic fluid alpha-fetoprotein heterogeneity. Br. Med. J. 1979; ii: 1402
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  • Buamah P. K., Taylor P., Milford-Ward A. Concanavalin A binding of alpha-fetoprotein in amniotic fluid as an aid in the diagnosis of neural tube defects. Clin. Chem. 1981; 27: 1658
  • Hindersson P., Toftager-Larsen K., Nørgaard-Pedersen B. Concanavalin A reactivity of amniotic fluid alpha-fetoprotein in diagnosis of neural tube defects. Lancet 1979; ii: 806
  • Noyes J. A., Wood P. J. Affinity chromatography of amniotic fluid alpha-fetoprotein using Concanavalin A-Sepharose. Ann. clin. Biochem. 1981; 18: 350
  • Ruoslahti E., Adamson E. Alpha-fetoproteins produced by the yolk sac and the liver are glycosylated differently. Biochem. biophys. Res. Commun. 1978; 85: 1622
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  • Ruoslahti E., Pekkala A., Comings D. E. Determination of subfractions of amniotic fluid alpha-fetoprotein in diagnosing spina bifida and congenital nephrosis. Br. Med. J. 1979; ii: 768
  • Ruoslahti E., Seppälä M. Studies of carcinofetal proteins, 3. Development of a radioimmunoassay for α-fetoprotein. Demonstration of α-fetoprotein in serum of healthy adults. Int. J. Cancer 1971; 8: 374
  • Ruoslahti E., Seppälä M. Alpha-fetoprotein in cancer and fetal development. Adv. Cancer Res. 1979; 29: 275
  • Seppälä M. Immunologic detection of alphafetoprotein as a marker of fetal pathology. Clin. Obstet. Gynecol. 1977; 20: 737
  • Smith C. J., Kelleher P. C., Bélanger L., Dallaire L. Reactivity of amniotic fluid alphafetoprotein with concanavalin A in diagnosis of neural tube defects. Br. Med. J. 1979; i: 920
  • Toftager-Larsen K., Kjaersgaard E., Nørgaard-Pedersen B. Reactivity of amniotic fluid alpha-fetoprotein with concanavalin A in relation to gestational age: Clinical implications. Clin. Chem. 1980; 26: 1656
  • Toftager-Larsen K., Kjaesgaard E., Nørgaard-Pedersen B. Comparison of amniotic fluid alpha-fetoprotein reactivity to Lens culinaris agglutinin and concanavalin A in crossed-affinity immunoelectrophoresis: Ancillary test in prenatal diagnosis of severe malformations. Clin. Chem. 1983; 29: 21
  • Wood P. J., Coombes E., Spencer K. Concanavalin A binding of alpha-fetoprotein in the diagnosis of neural tube defects—a word of caution. Clin. Chem. 1982; 28: 1231, (letter)

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