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Scandinavian Journal of Clinical and Laboratory Investigation Volume 47, 1987 - Issue 6
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Original Article

On the unreliability of one-stage factor VIII:C clotting assays after infusion of factor VIII concentrates

M. Blombäck Department of Clinical Chemistry and Blood Coagulation, Karolinska Hospital, Stockholm, Sweden
,
H. Kjellman Ringgau-Datterode, FRG
,
J. P. Allain Centre National de Transfusion Sanguine, Paris, France
,
U. Hedner Department for Coagulation Disorders, University of Lund, Malmö, General Hospital, Malmö, Sweden
,
Kl. Schimpf Rehabilitation Hospital and Hemophilia Center Heidelberg, Rehabilitation Foundation, Heidelberg, FRG
&
B. Wiechel Stockholm County Council Blood Transfusion Service, Södersjukhuset, Stockholm, Sweden
Pages 561-566 | Received 17 Nov 1986, Accepted 02 Mar 1987, Published online: 17 Mar 2010

References

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  • Abildgaard C F, Cornet J A, Fort E, Schulman I. The in vivo longevity of antihaemophilic factor (Factor VIII). Br J Haematol 1964; 10: 225–37
  • Allain J P, Steinbuch M, Meunier L, Muller J Y, Soulier J P. Traitement substitutif de rhemophilie A par un nouveau concentre de facteur VIII. Nouv Presse Med 1976; 5: 1047–50
  • Johnson A J, Karpatkin M H, Newman J. Clinical investigation of intermediate and high purity antihaemophilic factor (Factor VIII) concentrates. Br J Haematol 1971; 21: 21–41
  • Hardisty R M, MacPherson J C. A one-stage factor VIII (antihemophilic globulin) assay and its use on venous and capillary plasma. Thromb Diath Haemorrh 1962; 7: 215–29
  • Soulier J P, Larrieu M J. Nouvelle methode de diagnostic de l'hémophilie. Dosage des facteurs antihémophiliques A et B. Le Sang 1953; 24: 205–15
  • Nilsson I M, Blombäck M, von Francken I. On an inherited hemorrhagic diathesis with antihemophilic globulin (AHG) deficiency and prolonged bleeding time. Acta Med Scand 1957; 159: 35–57
  • Nilsson I M, Kirkwood T BL, Barrowcliffe T W. In vivo recovery of factor VIII: a comparison of one-stage and two-stage assay methods. Thromb Haemost 1979; 42: 1230–9
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  • Lusher J M, Ofosu F A, Edison J R, Hoist J H, Chavin S I, Weiss A E, Hillman C RL. North American study of factor VIII concentrate potency. Scand J Haematol 1984; 33(Suppl. 40)149–60
  • Schimpf K L, Rothmann P, Schumacher K. Comparison of factor VIII concentrates in non-bleeding patients. Factor VIII concentrates and their clotting activity. Scand J Haematol 1984; 33(Suppl. 41)131–45
  • van Gastel C, Sixma J J, Borst-Eilers E, Leautaud M, Moes M, van der Plas P M, Bouma B N, Sybesma J P. Preparation and infusion of cryoprecipitate from exercised donors. Br J Haematol 1973; 25: 461–6
  • Kasper C K. In vivo recovery of F VCIII:C in hemophilic patients. Scand J Haematol 1984; 33(Suppl. 41)147–54
  • Ofosu F A, Blajchman M A, Barr R, Inwood M. Approaches to the measurement of the in vivo response to factor VIII concentrate infusion. Thromb Res 1985; 39: 429–437

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