5
Views
9
CrossRef citations to date
0
Altmetric
Original Article

β-adrenergic receptors of human lymphocytes in physically active and immobilized subjects: Characterization by a polyethylene glycol precipitation assay

, , &
Pages 261-267 | Received 02 Jul 1986, Accepted 14 Nov 1986, Published online: 17 Mar 2010

References

  • Motulsky H J, Insel P A. Adrenergic receptors in man. Direct identification, physiologic regulation, and clinical alterations. New Engl J Med 1982; 307: 18–29
  • Lefkowitz R J. Clinical physiology of adrenergic receptor regulation. Am J Physiol 1982; 243: E43–E47
  • Lefkowitz R J, Caron M G, Stiles G L. Mechanism of membrane-receptor regulation. Biochemical, physiological, and clinical insights derived from studies of the adrenergic receptors. New Engl J Med 1984; 310: 1570–9
  • Sibley D R, Lefkowitz R J. Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model. Nature 1985; 317: 124–9
  • Lefkowitz R J. Direct binding studies of adrenergic receptors: Biochemical, physiologic, and clinical implications. Ann Int Med 1979; 91: 450–8
  • Williams R S. Physical conditioning and membrane receptors for cardioregulatory hormones. Cardiovasc Res 1980; 14: 177–82
  • Williams R S, Eden R S, Moll M E, Lester R M, Wallace A G. Autonomic mechanisms of training bradycardia: β-adrenergic receptors in human. J Appl Physiol 1981; 51: 1232–7
  • Butler J, O'Brien M, O'Malley K, Kelly J G. Relationship of β-adrenoreceptor density to fitness in athletes. Nature 1982; 298: 60–2
  • Lehmann M, Dickhuth H H, Schmid P, Porzig H, Keul J. Plasma catecholamines, β-adrenergic receptors, and isoproterenol sensitivity in endurance trained and non-endurance trained volunteers. Eur J Appl Physiol 1982; 52: 362–9
  • Brodde O-E, Engel G, Hoyer D, Bock K D, Weber F. The β-adrenergic receptor in human lymphocytes: Subclassification by the use of a new radio-ligand, (±)-125iodocyanopindolol. Life Sci 1981; 29: 2189–98
  • Böyum A. Isolation of mononuclear cells and granulocytes from human blood. Scand J Clin Lab Invest 1968, Suppl. 97: 77–89
  • Scatchard G. The attraction of proteins for small molecules and ions. Ann NY Acad Sci 1949; 51: 660–72
  • Lowry O H, Rosebrough N Y, Farr A L, Randall R Y. Protein measurement with the Folin phenol reagent. J Biol Chem 1957; 193: 265–75
  • Korenman S G. Relation between estrogen inhibitory activity and binding to cytosol of rabbit and human uterus. Endocrinology 1970; 87: 1119–23
  • Williams R S, Guthrow C E, Lefkowtz R J. β-Adrenergic receptors of human lymphocytes are unaltered by hyperthyroidism. J Clin Endocrinol Metab 1979; 48: 503–5
  • Davies A O, Lefkowitz R J. Corticosteroid-induced differential regulation of β-adrenergic receptors in circulating human polymorphonuclear leukocytes and mononuclear leukocytes. J Clin Endocrinol Metab 1980; 51: 599–605
  • Tohmeh J F, Cryer P E. Biphasic adrenergic modulation of β-adrenergic receptors in man. J Clin Invest 1980; 65: 836–40
  • Aarons R D, Nies A S, Gal J, Hegstrand L R, Molinoff P B. Elevation of β-adrenergic receptor density in human lymphocytes after propranolol administration. J Clin Invest 1980; 65: 949–57
  • Galant S P, Duriseti L, Underwood S, Insel P. Decreased beta-adrenergic receptors on polymorphonuclear leukocytes after adrenergic therapy. New Engl J Med 1978; 299: 933–6
  • de Jonge H. Inleiding tot de Medischc Stutistiek. Deel II, 2nd edn. Verhandeling van het Neder-lands Instiuut voor Preaventieve Geneeskunde, Leiden 1964; 486–7

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.