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Original Article

Effect of somatostatin on liver blood flow and liver metabolic activity in patients with cirrhosis

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Pages 667-672 | Received 03 Feb 1987, Accepted 23 Apr 1987, Published online: 17 Mar 2010

References

  • Tyden G, Samnegaard H, Thulin L, Friman L, Efendic S. Treatment of bleeding esophageal varices with somatostatin. Letter. N Engl J Med 1979; 299: 1466–7
  • Thulin L, Tyden G, Samnegaard H, Muhrbeck O, Efendic S. Treatment of bleeding oesophageal varices with somatostatin. Acta Chir Scand 1979; 145: 395–8
  • Bories P, Pomier-Layargues G, Chotard J P, Jacob C, Michel H. La somatostatine diminue l'hypertensione portale chez le cirrhotique. Gastroenterol Clin Biol 1980; 4: 616–7
  • Bosch J, Kravetz D, Rodes J. Effect of somatostatin on hepatic and systemic hemodynamics in patients with liver cirrhosis: Comparison with vasopressin. Gastroenterology 1981; 80: 518–25
  • Raptis S, Zoupas C. Somatostatin not helpful in bleeding esophageal varicel. Letter. N Engl J Med 1979; 301: 736–7
  • Sonnenberg G E, Keller U, Perruchod A, Burkhardt D, Gyr K. Effect of somatostatin on splanchnic hemodynamics in patients with liver cirrhosis and in normal subjects. Gastroenterology 1981; 80: 526–32
  • Merkel C, Gatta A, Zuin R, Finucci G F, Nosadini R, Ruol A. Effect of somatostatin on splanchnic hemodynamics in patients with liver cirrhosis and portal hypertension. Digestion 1985; 32: 92–8
  • Barbare J C, Poupon R, Jaillon P, Bories P, Aussanaire M, Darnis F, Michel H, Cheymol G. The influence of vasoactive agents on metabolic activity of the liver in cirrhosis: A study of the effects of posterior pituitary extract, vasopressin and somatostatin. Hepatology 1984; 4: 59–62
  • Caesar J, Shaldon S, Chiandussi L, Guevara L, Sherlock S. The use of indocyanine green in the measurement of hepatic blood flow and as a test of hepatic function. Clin Sci 1961; 21: 43–57
  • Gatta A, Sacerdoti D, Merkel C, Milani L, Battaglia G, Zuin R. Effects of nadolol treatment on renal and hepatic hemodynamics and function in cirrhotic patients with portal hypertension. Am Heart J 1984; 108: 1167–72
  • Merkel C, Sacerdoti D, Finucci G F, Zuin R, Bazzerla G, Bolognesi M, Gatta A. Effect of nadolol on liver hemodynamics and function in patients with cirrhosis. Br J Clin Pharmacol 1986; 21: 713–9
  • Rowell L B. Measurement of hepatic-splanchnic blood flow in man by dye-dilution curves. Dye curves: The Theory and Practice of Indicator Dilution, D A Bloomfield. University Park Press, Baltimore 1975; 209–25
  • Barbare J C, Poupon R, Jaillon P, Proud'homme S, Poupon R Y. Intrinsic hepatic clearance and Child-Turcotte classification for assessment of liver function in cirrhosis. J Hepatol 1985; 1: 253–9
  • Bass L, Keiding S, Winkler K, Tygstrup N. Enzymatic elimination of substances flowing through the intact liver. J Theor Biol 1976; 61: 393–410
  • Eriksson L E, Law D H, Sato Y, Wahren J. Influence of somatostatin on splanchnic hemodynamics in patients with cirrhosis. Clin Physiol 1984; 4: 5–11
  • Samnegaard H, Thulin L, Andreen M, Tyden G, Hallberg D, Efendic S. Circulatory effect of somatostatin in anaesthetized dog. Acta Chir Scand 1979; 145: 209–12
  • Winkler K, Bass L, Keiding S, Tygstrup N. The physiologic basis for clearance measurements in hepatology. Scand J Gasroenterol 1979; 14: 439–48
  • Pang K S, Rowland M. Hepatic clearance of drugs. I. Theoretical considerations of a ‘well-stirred’ model and a ‘parallel tube’ model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance. J Pharmacokinetic Biopharm 1977; 5: 625–53
  • Keiding S, Chiarantini E. Effect of sinusoidal perfusion on galactose elimination kinetics in perfused rat liver. J Pharmacol Exp Ther 1978; 205: 465–70
  • Pessayre D, Lebrec D, Descatoire V, Peygnoux M, Benhamou J P. Intrinsic hepatic clearance in cirrhosis. Letter. Gastroenterology 1978; 75: 346

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