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Original

The effect of Acipimox on triacylglycerol metabolism in rat

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Pages 203-208 | Received 26 Jun 1989, Accepted 21 Sep 1989, Published online: 29 Mar 2011

References

  • Lovisolo P P, Briatico Vangosa G, Orsini G, Ronchi R, Angelucci R. Pharmacological profile of a new anti-lipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (Acipimox)-mechanism of action. Pharm Res Comm 1981; 13: 150–61
  • Carlson L A, Oro L. The effect of nicotinic acid on plasma free fatty acids. Demonstration of a metabolic type of sympathicolysis. Acta Med Scand 1962; 172: 641–5
  • Carlson L A, Havel R J, Ekelund L G, Holmgren A. Effect of nicotinic acid on turnover rate and oxidation of the free fatty acids of plasma in man during exercise. Metabolism 1963; 12: 837–45
  • Carlson L A. Studies on the effect of nicotinic acid on catecholamine stimulate lipolysis in adipose tissue in vitro. Acta Med Scand 1963; 173: 719–22
  • Bell R M, Coleman R M. Enzymes of glycerolipid synthesis in eukaryotes. Ann Rev. Biochem 1980; 49: 459–87
  • Fallon H J, Lamb R G, Jamdar S C. Phosphatidate phosphohydrolase and the regulation of glycerolipid biosynthesis. Biochem Soc Trans 1977; 5: 37–40
  • Brindley D N. Regulation of fatty acid esterifica-tion in tissue. FEBS, Federation of European Biochem. Soc, 11th Meeting, R. Dils, J Knudsen. Pergamon Press, Oxford 1978; Vol 46: 31–40, Sy A5
  • Berglund L, Björkhem I, Einarsson K. Apparent phosphorylation — dephosphorylation of soluble phosphatidic acid phosphatase in rat liver. Biochem Biophys Res Comm 1982; 105: 288–95
  • Otway S, Robinson D S. A non-ionic detergent (Triton WR 1339) to determine rates of triglyceride entry into the circulation of the rat under different physiological conditions. J Physiol 1967; 190: 321–32
  • Bates E J, Saggerson D. A selective decrease in mitochondrial glycerol phosphate acyltransferase activity in livers from streptozotocin-diabetic rats. FEBS Lett 1977; 84: 229–32
  • Daae L NW, Bremer J. The acylation of glycerophosphate in rat liver: A new assay procedure for glycerophosphate acylation, studies on its subcellular and submitochondrial localization and determination of the reaction products. Biochim Biophys Acta 1970; 210: 92–104
  • Coleman R, Bell R M. Triacylglycerol synthesis in isolated fat cells: Studies on the microsomal diacylglycerol acyltransferase activity using ethanol-dispersed diacylglycerol. J Biol Chem 1976; 25: 4537–43
  • Lowry O H, Rosebrough M J, Farr A L, Randall R J. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193: 265–75
  • Folch J, Lees M, Sloane Stanley G H. A simple method for the isolation and purification of total lipids from animal tissue. J Biol Chem 1957; 226: 497–509
  • Shimizu S, Yasui K, Taniand Y, Yamada H. Acyl-CoA oxidase from Candida tropicalis. Biochem Biophys Res Comm 1979; 91: 108–13
  • Mulder C, Schouten J A, Popp-Snijders C. Determination of free fatty acids: a comparative study of the enzymatic versus the gas chromatographic and colorimetric method. J Clin Chem Biochem 1983; 21: 823–7
  • Steiner G, Haynes F J, Yoshino G, Vranic M. Hyperinsulinemia and in vivo very-low-density lipoprotein-triglyceride kinetics. Am J Physiol 1984; 246: E 187–92
  • Fiser R H, Jr, Denniston J C, Rindsig R B, Beisel W R. Triglyceride secretion rates: use of Triton WR 1339 in the rhesus monkey. J Nutr 1974; 104: 223–6
  • Grundy S, Mok H YI, Zech L, Berman M. Influence of nicotinic acid on metabolism of cholesterol and triglycerides in man. J Lipid Res 1981; 22: 24–36
  • Brindley D N. Intracellular translocation of phos-phatidate phosphohydrolase and its possible role in the control of glycerolipid synthesis. Progr Lipid Res 1984; 23: 115–33
  • Stirling C, McAleer M, Reckless J PD, et al. Effect of Acipimox, a nicotinic acid derivative, on lipolysis in human adipose tissue and on cholesterol synthesis in human jejunal mucosa. Clin Sci 1985; 68: 83–8
  • Angelin B, Ericsson S, Eriksson M, Berglund L. Effects of nicotinic acid in lipoprotein metabolism and biliary lipids. Atherosclerosis VIII, G Crepaldi, et al. Elsevier Sci Publ BV, Amsterdam 1989; 795–8

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