29
Views
33
CrossRef citations to date
0
Altmetric
Original Article

No effect of a very low dose of n-3 fatty acids on monocyte function in healthy humans

, , , , &
Pages 87-92 | Received 29 May 1995, Accepted 27 Sep 1995, Published online: 29 Mar 2011

References

  • Shekelle RB, Stamler J. Fish and coronary heart disease: the epidemiologic evidence. Nutr Metab Cardiovasc Dis 1993; 3: 46–51
  • Bang HO, Dyerberg J, Sinclair HM. The composition of Eskimo food in north-western Greenland. Am J Clin Nutr 1980; 33: 2657–61
  • Bjerregaard P. Disease pattern in Greenland: Studies on morbidity in Upernavik 1979–1980 and mortality in Greenland 1968–1985. Arctic Med Res 1991; 50: 1–62, Suppl 4
  • Kagawa Y, Nishizawa M, Suzuki M, Miyatake T, Hamamoto T, Goto K, et al. Eicosapolyenoic acids of serum lipids of Japanese Islanders with low incidence of cardiovascular diseases. J Nutr Sci Vitaminol 1982; 28: 441–53
  • Newman WP, Middaugh JP, Propst MT, Rogers DR. Atherosclerosis in Alaska natives and non-natives. Lancet 1993; 341: 1056–7
  • Kromhout D, Bosschieter EB, Coulander CdL. The inverse relation between fish consumption and 20-year mortality from coronary heart disease. N Engl J Med 1985; 312: 1205–9
  • Shekelle RB, Missell LV, Paul O, Shryock AM, Stamler J. Fish consumption and mortality from coronary heart disease. N Engl J Med 1985; 313: 820
  • Norell SE, Ahlbom A, Feychting M, Pedersen NL. Fish consumption and mortality from heart disease. Br Med J 1986; 293: 426
  • Gramenzi A, Gentile A, Fasoli M, Negri E, Parazzini F, Vecchia CL. Association between certain foods and risk of acute myocardial infarction in women. Br Med J 1990; 300: 771–3
  • Dolecek TA, Grandits G. Dietary polyunsaturated fatty acids and mortality in the multiple risk factor intervention trial (MRFIT). World Rev Nutr Diet 1991; 66: 205–16
  • Burr ML, Fehily AM, Gilbert JF, Rogers S, Holliday RM, Sweetnam PM, et al. Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: Diet and reinfarction trial (DART). Lancet 1989; ii: 757–60
  • de Lorgeril M, Renaud S, Mamelle N, Salen P, Martin J-L, Monjaud I, et al. Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease. Lancet 1994; 343: 1454–9
  • Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993; 362: 801–9
  • Nordøy A. Is there a rationale use for n-3 fatty acids (fish oils) in clinical medicine?. Drugs 1991; 42: 331–42
  • Schmidt EB, Pedersen JO, Varming K, Ernst E, Jersild C, Grunnet N, et al. n-3 Fatty acids and leucocyte chemotaxis: effects in hyperlipidemia and dose-response studies in healthy males. Arterioscler Thromb 1991; 11: 429–35
  • Powell WS. High-pressure liquid chromatography in the analysis of arachidonic acid metabolites. Prostaglandins and related substances, C Benedetto, RG McDonald-Gibson, S Nigam, TF Slater. IRL Press, Oxford 1987; 75–98
  • Lagarde M, Croset M, Véricel E, Calzada C. Effects of small concentrations of eicosapentaenoic acid on platelets. J Intern Med 1989; 225: 177–9, Suppl 1
  • Winther K, Myrup B, Hølmer G, Høy C-E, Mehlsen J, Schnohr P. Decreased platelet activity without change in fibrìnolytic activity after low dosages of fish oil. Angiology 1993; 8: 39–44
  • Lervang HH, Schmidt EB, Møller J, Svaneborg N, Vaming K, Madsen PH, et al. The effect of low-dose supplementation with n-3 polyunsaturated fatty acids on some risk markers of coronary heart disease. Scand J Clin Lab Invest 1993; 53: 417–23
  • Lee TH, Hoover RL, Williams JD, Sperling RI, Ravalese J, Spur BW, et al. Effect of dietary enrichment with eicosapentaenoic acid and docosahexaenoic acids on in vitro neutrophil and mono-cyte leukotriene generation and neutrophil function. N Engl J Med 1985; 312: 1217–24
  • Schmidt EB, Dyerberg J. n-3 Fatty acids and leucocytes. J Intern Med 1989; 225: 151–8, Suppl 1
  • Schmidt EB, Pedersen JO, Ekelund S, Grunnet N, Jersild C, Dyerberg J. Cod liver oil inhibits neutrophil and monocyte chemotaxis in healthy males. Atherosclerosis 1989; 77: 53–7
  • Schmidt EB, Varming K, Pedersen JO, Lervang H-H, Grunnet N, Jersild C, et al. Long-term supplementation with n-3 fatty acids, II: Effect on neutrophil and monocyte chemotaxis. Scand J Clin Lab Invest 1992; 52: 229–36
  • Fisher M, Levine PH, Weiner BH, Johnson MH, Doyle EM, Ellis PA, et al. Dietary n-3 fatty acid supplementation reduces superoxide production and chemiluminescence in a monocyte-enriched preparation of leukocytes. Am J Clin Nutr 1990; 51: 804–8
  • Hansen J-B, Olsen JO, Wilsgård L, Østerud B. Effects of dietary supplementation with cod liver oil on monocyte thromboplastin synthesis, coagulation and fibrinolysis. J Intern Med 1989; 225: 133–9, Suppl 1
  • Tremoli E, Eligini S, Colli S, Maderna P, Risé P, Pazzucconi F, et al. n-3 Fatty acid ethyl ester administration to healthy subjects and to hypertrig-lyceridemic patients reduces tissue factor activity in adherent monocytes. Arterioscler Thromb 1994; 14: 1600–8
  • Kaminski WE, Jendraschak E, Kiefl R, von Schacky C. Dietary Ω-3 fatty acids lower levels of platelet-derived growth factor mRNA in human mononuclear cells. Blood 1993; 81: 1871–9
  • Endres S, Ghorbani R, Kelley VE, Georgilis K, Lonnemann G, van der Meer JWM, et al. The effect of dietary supplementation with n-3 polyun-saturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mono-nuclear cells. N Engl J Med 1989; 320: 265–71
  • Mølvig J, Pociot F, Worsaa H, Wogensen LD, Baek L, Christensen P, et al. Dietary supplementation with Ω-3 polyunsaturated fatty acids decreases mononuclear cell proliferation and interleukin-1 β content but not monokine secretion in healthy and insulin-dependent diabetic individuals. Scand J Immunol 1991; 34: 399–410
  • Endres S, Meydani SN, Ghorbani R, Schindler R, Dinarello CA. Dietary supplementation with n-3 fatty acids suppresses interleukin-2 production and mononuclear cell proliferation. J Leuc Biol 1993; 54: 599–603
  • De Caterina R, Cybulsky MI, Clinton SK, Gimbrone MA, Jr, Libby P. The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells. Arterioscler Thromb 1994; 14: 1829–36
  • Ferrante A, Goh D, Harvey DP, Robinson BS, Hii CST, Bates EJ, et al. Neutrophil migration inhibitory properties of polyunsaturated fatty acids. The role of fatty acid structure, metabolism, and possible second messenger systems. J Clin Invest 1994; 93: 1063–70
  • Sperling RI, Benincaso AI, Knoell CT, Larkin JK, Austen KF, Robinson DR. Dietary Ω-3 polyunsaturated fatty acids inhibit phosphoinositide formation and chemotaxis in neutrophils. J Clin Invest 1993; 91: 651–60
  • Meydani SN, Lichtenstein AH, Cornwall S, Meydani M, Goldin BR, Rasmussen H, et al. Immunologic effects of National Cholesterol Education Panel step-2 diets with and without fish-derived n-3 fatty acid enrichment. J Clin Invest 1993; 92: 105–13

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.