References
- Hauschka P V, Lian J B, Cole D EC, Gundberg C M. Osteocalcin and matrix Gla protein: vitamin K dependent proteins in bone. Phys Rev 1989; 69: 990–1047
- Price P A. Role of vitamin K-dependent proteins in bone metabolism. Annu Rev Nutr 1988; 8: 565–83
- Vermeer C. Gamma-carboxyglutamate-containing proteins and the vitamin K-dependent carboxylase. Biochem J 1990; 266: 625–36
- Furie B, Furie B C. Molecular basis of vitamin K-dependent γ-carboxylation. Blood 1990; 75: 1753–62
- Brown J P, Delmas P D, Malaval L, Edouard C, Chapuy M C, Meunier P J. Serum bone Gla-protein: a specific marker for bone formation in postmenopausal osteoporosis. Lancet 1984; i: 1091–3
- Ismail F, Epstein S, Pacific R, Droke D, Thomas S B, Avioli L V. Serum bone Gla protein (BGP) and other markers of bone mineral metabolism in postmenopausal osteoporosis. Calcif Tissue Int 1986; 39: 230–3
- Price P A, Parthemore J G, Deftos L J, Nishimoto S K. New biochemical marker for bone metabolism. Measurement by radioimmunoassay of bone Gla protein in the plasma of normal subjects and patients with bone disease. J Clin Invest 1980; 66: 878–83
- Power M J, Fottrell P F. Osteocalcin: diagnostic methods and clinical applications. Crit Rev Clin Lab Sci 1991; 28: 287–335
- Dí;az Diego E M, Guerrero R, de la Piedra C. Six osteocalcin assays compared. Clin Chem 1994; 40: 2071–7
- Knapen M HJ, Eisenwiener H-G, Vermeer C. Osteocalcin detection in aging serum and whole blood: stability of different osteocalcin fractions. Clin Chim Acta, in press
- Hart J P, Catterall A, Dodds R A, Klenerman L, Shearer M J, Bitensky L, Chayen J. Circulating vitamin K1 levels in fractured neck of femur. Lancet 1984; ii: 283
- Hart J P, Shearer M J, Klenerman L, Caterall A, Reeve J, Sambrook P N, Dodds R A, Bitensky L, Chayen J. Electrochemical detection of depressed circulating levels of vitamin K1 in osteoporosis. J Clin Endocrinol Metab 1985; 60: 1268–9
- Bitensky L, Hart J P, Caterall A, Hodges S J, Pilkington M J, Chayen J. Circulating vitamin K levels in patients with fractures. J Bone Joint Surg 1988; 70-B: 663–4
- Hodges S J, Akesson K, Vergnaud P, Obrant K, Delmas P D. Circulating levels of vitamins K1 and K2 decreased in elderly women with hip fracture. J Bone Miner Res 1993; 8: 1241–5
- Jie K-S G, Bots M L, Vermeer C, Witteman J CM, Grobbee D E. Vitamin K status and bone mass in women with and without aortic atherosclerosis: a population-based study. Calcif Tissue Int 1996; 59: 352–6
- Knapen M HJ, Hamulyák K, Vermeer C. The effect of vitamin K supplementation on circulating osteocalcin (bone Gla-protein) and urinary calcium excretion. Ann Int Med 1989; 111: 1001–5
- Knapen M HJ, Jie K-SG, Hamulyák K, Vermeer C. Vitamin K-induced changes in markers for osteoblast activitiy and urinary calcium loss. Calcif Tissue Int 1993; 53: 81–5
- Szulc P, Arlot M, Chapuy M-C, Duboeuf F, Meunier P J, Delmas P D. Serum undercarboxylated osteocalcin correlates with hip bone mineral density in elderly women. J Bone Miner Res 1994; 9: 1591–5
- Szulc P, Chapuy M-C, Meunier P J, Delmas P D. Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture in elderly women. J Clin Invest 1993; 91: 1769–74
- Chu K, Wu S-M, Stanley T, Stafford D W, High K A. A mutation in the propeptide of factor IX leads to warfarin sensitivity by a novel mechanism. J Clin Invest 1996; 98: 1619–25
- Cairns J R, Price P A. Direct demonstration that the vitamin K-dependent bone Gla protein is incompletely γ-carboxylated in humans. J Bone Miner Res 1994; 9: 1989–97
- Nakao M, Nishiuchi Y, Nakata M, Kimura T, Sakakibara S. Synthesis of human osteocalcins: γ-carboxyglutamic acid at position 17 is essential for a calcium-dependent conformational transition. Pept Res 1994; 7: 171–4
- Chang G TG, Ploos van Amstel H K, Hessing M, Reitsma P H, Bertina R M, Bouma B N. Expression and characterization of recombinant human protein S in heteologous cells - Studies of the interaction of amino acid residues Leu-608 to Glu-612 with human C4b-binding protein. Thromb Haemostas 1992; 67: 526–32
- Christiansen W T, Castellino F J. Properties of recombinant chimeric human protein C and activated protein C containing the γ-carboxyglutamic acid and trailing helical stack domains of protein C replaced by those of human coagulation factor IX. Biochemistry 1994; 33: 5901–11