Lack of thyroglobulin synthesis as an indicator of early random dedifferentiation of the Fischer rat thyroid cell line FRTL-5

REFERENCES

• Ambesi-Impiombato FS, Parks LAM, Coon HG. Culture of hormone dependent functional epithe-lial cells from rat thyroids. Proc Natl Acad Sci 1980; 77: 3455–9.
   PubMed Web of Science ®Google Scholar
• Ambesi-Impiombato FS, Picone R, Tramontano D. Influence of hormones and serum on growth and differentiation of the thyroid cell strain FRTL. In: Sato GH, Pardee A, Sirbasku DA, editors. Growth of cells in hormonally defined media. New York: Cold Spring Harbor Laboratory, 1982: 483–92.
   Google Scholar
• Ambesi-Impiombato FS, Villone G. The FRTL-5 thyroid cell strain as a model for studies on thyroid cell growth. Acta Endocrinol Suppl 1987; 281: 242 — 5.
   Google Scholar
• Bidey SP, Lambert A, Robertson WR. Thyroid cell growth, differentiation and function in the FRTL-5 cell line: a survey. J Endocrinol 1988; 119: 365 — 76.
   Google Scholar
• Weiss SJ, Philp NJ, Ambesi-Impiombato FS, Grollman EF. Thyrotropin-stimulated iodide transport mediated by adenosine 3',5'-monopho-sphate and dependent on protein synthesis. Endo-crinol 1984; 114: 1099 — 107.
   Google Scholar
• Marcocci C, Pinchera A, Grollman EF. Sodium/ proton exchange in FRTL-5 thyroid cells: Role in the maintenance of intracellular pH and TSH-sti-mulated cell growth. Acta Endocrinol Suppl 1987; 281: 293 — 6.
   Google Scholar
• Di Jeso B, Formisano S, Ulianich L. Perturbation of cellular calcium delays the secretion and alters the glycosylation of thyroglobulin in FRTL-5 cells. Bichem Biophys Res Commun 1997; 234: 133 — 6.
   Google Scholar
• Di Jeso B, Pereira R, Consiglio E, Formisano S, Satrustegui J, Sandoval IV. Demonstration of a Ca2+ requirement for thyroglobulin dimerisation and export to Golgi complex. Eur J Biochem 1998; 252: 583–90.
   PubMedGoogle Scholar
• Rasmussen AK, Feldt-Rasmussen U, Bendtzen K. The effect of interleukin-1 on the thyroid gland. Autoimmunity 1993; 16: 141 — 8.
   PubMedGoogle Scholar
• Pang X, Hershman JM. Differential effects of growth factors on 3H-thymidine incorporation and 1251 iodine uptake in FRTL-5 rat thyroid cells. Proc Soc Exp Biol Med 1990; 193: 240–4.
   Google Scholar
• Avvedimento YE, Monticelli A, Tramontano D, Polistina C, Nitsch L, Di Lauro R. Differential expression of thyroglobulin gene in normal and transformed thyroid cells. Eur J Biochem 1985; 149: 467–72.
   Google Scholar
• Monaco C, Califano D, Chiappetta G, Mineo A, De Franciscis V, Vecchio G, Santelli G. Mutated human Kirsten ras, driven by a thyroglobulin pro-moter, induces a growth advantage and partially dedifferentiates rat thyroid epithelial cells in vitro. J Cancer 1995; 63: 757 — 60.
   Google Scholar
• Berlingieri MT, Musti AM, Avvedimento YE, Di Lauro R, Di Fiore PP, Fusco A. The block of thyr-oglobulin synthesis, which occurs upon transfor-mation of rat thyroid epithelial cells is at the transcriptional level and it is associated with methylation of the 5'flanking region of the gene. Exp Cell Res 1989; 183: 277 — 83.
   Google Scholar
• Fusco A, Berlingieri MT, Di Fiore PP, Portella G, Grieco M, Vecchio G. One- and two-step transfor-mations of rat thyroid epithelial cells by retroviral oncogenes. Mol Cell Biol 1987; 7: 3365–70.
   PubMed Web of Science ®Google Scholar
• Van der Kallen CJ, Spierings DC, Thijssen JH, Blankenstein MA, de Bruin TW. Disrupted co-ordination of Pax-8 and thyroid transcription fac-tor-1 gene expression in a dedifferentiated rat thyr-oid tumour cell line derived from FRTL-5. J Endocrinol 1996; 150: 377 — 82.
   PubMedGoogle Scholar
• Berlingieri MT, Santoro M, Battaglia C, Grieco M, Fusco A. The adenovirus ElA gene blocks the dif-ferentiation of a thyroid epithelial cell line, however the neoplastic phenotype is achieved only after co-operation with other oncogenes. Oncogene 1993; 8: 249 — 55.
   Google Scholar
• Pekary AE, Berg L, Wang J, Lee P, Dubinett SM, Hershman JM. TNF-a, TSH, and aging regulate TGF-I3 synthesis and secretion in FRTL-5 rat thyr-oid cells. Am J Physiol 1995: R808 —15.
   Google Scholar
• Chen GE, Pekary AE, Hershman JM. Aging of FRTL-5 rat thyroid cells causes sensitivity to cyto-toxicity induced by tumor necrosis factor-a. Endo-crinol 1992; 131: 863–9.
   Google Scholar
• Bidey SP, Chiovato L, Day A, Turmaine M, Gould RP, Ekins RP, Marshall NJ. Evaluation of the rat thyroid cell strain FRTL-5 as an in vitro bioassay system for thyrotropin. J Endocrinol 1984; 281: 293 — 6.
   Google Scholar
• Bellur S, Tahara K, Sajl M, Grollman EF, Kohn LD. Repeatedly passed FRTL-5 rat thyroid cells can develop insulin and insulin-like growth factor-1-sensitive cyclooxygenase and prostaglandin E2 isomerase-like activities together with altered basal and thyrotropin-responsive thymidine incorpora-tion into DNA. Endocrinol 1990; 127: 1526 — 40.
   Google Scholar
• Madsen SN, Badawi I, Skovsted L. A simple com-petitive protein-binding assay for adenosine-3',5'-monophosphate in plasma and urine. Acta Endo-crinol 1976; 81: 208 — 14.
   Google Scholar
• Giles KW, Myers A. An improved diphenylamine method for the estimation of deoxyribonucleic acid. Nature 1965: 4979–93.
   Google Scholar
• Kohn LD, Valente W. FRTL-5 Today. Amsterdam. Excerpta Medica International Congress series 818, 1989: 243–73.
   Google Scholar
• Leer LM, Cammenga M, Van der Vorm ER, De Vijlder JJM. Methimazole increases thyroid-speci-fic mRNA concentration in human thyroid cells and FRTL-5 cells. Moll Cell Endocrinol 1991; 78: 221 — 8.
   Google Scholar
• Rasmussen AK, Kayser L, Perrild H, Brandt M, Bech K, Feldt-Rasmussen U. Human thyroid epithelial cells cultured in monolayers. I. Decreased thyroglobulin and cAMP response to TSH in 12-week-old secondary and tertiary cultures. Mol Cell Endocrinol 1996; 116: 165 — 72.
   Google Scholar
• Jin S, Hornicek FJ, Neylan D, Zakarija M, Mckenzie JM. Evidence that adenosine 3',5'-mono-phosphate mediate stimulation of thyroid growth in FRTL-5 cells. Endocrinol 1986; 119: 802— 10.
   Google Scholar
• Valente W, Vitti P, Kohn LD, Brandi ML, Rotella CM, Toccafondi R. The relationship of growth and adenylate cyclase activity in cultured thyroid cells: Separate bioeffects of thyrotropin. Endocrinol 1983; 112: 71–9.
   PubMed Web of Science ®Google Scholar
• Rasmussen AK, Kayser L, Perrild H, Brandt M, Bech K, Feldt-Rasmussen U. Human thyroid epithelial cells cultured in monolayers. II. Influence of serum on thyroglobulin and cAMP production. Moll Cell Endocrinol 1996; 116: 173–9.
   Google Scholar
• Isozaki 0, Santisteban P, Chan J, Grollman E, Kohn L. Insulin and insulin-like growth factor-1 (IGF-1) regulate differentiation as well as growth in FRTL-5 cells. Endocrinol Suppl 1987; 281: 288 — 92.
   Google Scholar
• Santisteban P, Kohn LD, Di Lauro R. Thyroglobu-lin gene expression is regulated by insulin and insu-lin-like growth factor 1, as well as thyrotropin in FRTL-5 cells. J Biol Chem 1987; 262: 4048 — 52.
   Google Scholar
• Kambe F, Seo H. Mediation of the hormone- and serum-dependent regulation of thyroglobulin gene expression by thyroid-transcription factors in rat thyroid FRTL-5 cells. J Endocrinol 1996 1996; 150: 287–98.
   Google Scholar