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Research Article

Concordance of Inflammatory Bowel Disease among Danish Twins: Results of a Nationwide Study

Pages 1075-1081 | Published online: 08 Jul 2009

References

  • Monsén U. Inflammatory bowel disease. An epidemiological and genetic study [thesis]. Stockholm, Sweden; 1990.
  • Orholm M, Munkholm P, Langholz E, Nielsen OH, S0rensen TIA, Binder V. Familial occurrence of inflammatory bowel disease. N Engl J Med 1991;324:84–8.
  • Monsén U, Iselius L, Johansson C, Hellers G. Evidence for a major additive gene in ulcerative colitis. Clin Genet 1989;36: 411–4.
  • Küster W, Pascoe L, Purrmann J, Funk S, Majewski F. The genetics of Crohn’s disease: complex segregation analysis of a family study with 265 patients with Crohn’s disease and 5,387 relatives. Am J Med Genet 1989;32: 105–8.
  • Orholm M, Iselius L, Sørensen TIA, Munkholm P, Langholz E, Binder V. Investigation of inheritance of chronic inflammatory bowel diseases by complex segregation analysis. Br Med J 1993;306:20–4.
  • Hugot J-P, Laurent-Puig P, Gower-Rousseau C, Olson JM, Lee JC, Beaugerie L, et al. Mapping of a susceptibility locus for Crohn’s disease on chromosome 16. Nature 1996;379:821–3.
  • Satsangi J, Parkes M, Louis E, Hashimoto L, Kato N, Welsh K, et al. Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12. Nature Genet 1996;14:199–202.
  • Tysk C, Lindberg E, Jarnerot G, Flodérus-Myrhed B. Ulcerative colitis and Crohn’s disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and influence of smoking. Gut 1988;29:990–6.
  • Thompson NP, Driscoll R, Pounder RE, Wakefield AJ. Genetics versus environment in inflammatory bowel disease: results of a British twin study. Br Med J 1996;312:95–6.
  • Kyvik KO, Green A, Beck-Nielsen H. The new Danish twin register: establishment and analysis of twining rates. Int J Epidemiology 1995;24:589–96.
  • Harries AD, Baird A, Rhodes J. Non-smoking: a feature of ulcerative colitis. Br Med J 1982;284: 706.
  • Lindberg E, Tysk C, Andersson K, Järnerot G. Smoking and inflammatory bowel disease. A case-control study. Gut 1988;29: 352–7.
  • Sandborn WJ, Tremaine WJ, Offord KP, Lawson GM, Petersen BT, Batts KP, et al. Transdermal nicotine for mildly to moderately active ulcerative colitis. A randomized, doubleblind, placebo-controlled trial. Ann Intern Med 1997;126:364–71.
  • Bayless TM, Tokayer AZ, Polito JM, Quaskey SA, Mellits D, Harris ML. Crohn’s disease: concordance for site and clinical type in affected family members—potential hereditary influences. Gastroenterology 1996;111:573–9.
  • Colombel J-F, Grandbastien B, Gower-Rousseau C, Plegat S, Evrard J-P, Dupas J-L, et al. Clinical characteristics of Crohn’s disease in 72 families. Gastroenterology 1996;111: 604–7.
  • Lee JWC, Lennard-Jones JE. Inflammatory bowel disease in 67 families each with three or more affected first-degree relatives. Gastroenterology 1996;111:587–96.
  • Peeters M, Nevens H, Baert F, Hiele M, Meyer A-Md, Vlietinck R, et al. Familial aggregation in Crohn’s disease: increased age-adjusted risk and concordance in clinical characteristics. Gastroenterology 1996;111:597–603.
  • Satsangi J, Grootscholten C, Holt H, Jewell DP. Clinical patterns of familial inflammatory bowel disease. Gut 1996;38:738–41.
  • Kyvik KO. Twin research: nature versus nurture in common diseases. In: Day INM, Humphries SE, editors. Genetics of common diseases, future therapeutic and diagnostic possibilities. Oxford: Bios Scientific Publishers; 1997.
  • Munkholm P, Langholz E, Nielsen OH, Kreiner S, Binder V. Incidence and prevalence of Crohn’s disease in the County of Copenhagen, 1962–87: a sixfold increase in incidence. Scand J Gastroenterol 1992;27: 609–14.
  • Langholz E, Munkholm P, Nielsen OH, Kreiner S, Binder V. Incidence and prevalence of ulcerative colitis in Copenhagen County from 1962 to 1987. Scand J Gastroenterol 1991;26: 1247–56.
  • Shivananda S, Lennard-Jones J, Logan R, Fear N, Price A, Carpenter L, et al. Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European collaborative study on inflammatory bowel disease (EC-IBD). Gut 1996;39:690–7.
  • Subhani J, Montgomery SM, Pounder RE, Wakefield AJ. Concordance rates of twins and siblings in inflammatory bowel disease. Gut 1998;42 Suppl 1:A40 (TW159).
  • Yang H, McElree C, Roth M-P, Shanahan F, Targan SR, Rotter JI. Familial empirical risks for inflammatory bowel disease: differences between Jews and non-Jews. Gut 1993;34:517–24.
  • Orholm M, Fonager K, Toft Sørensen H. Risk of ulcerative colitis and Crohn’s disease among offspring of patients with chronic inflammatory bowel disease. Am J Gastroenterol 1999; 94:3236–8.
  • Kirsner JB, Spencer JA. Family occurrence of ulcerative colitis, regional enteritis, and ileocolitis. Ann Intern Med 1963;59:133–44.
  • Roth M-P, Petersen GM, McElree C, Vadheim CM, Panish JF, Rotter JI. Familial empiric risk estimates of inflammatory bowel disease in Ashkenazi Jews. Gastroenterology 1989;96:1016–20.
  • Monsén U, Broström O, Nordenvall B, Sörstad J, Hellers G. Prevalence of inflammatory bowel disease among relatives of patients with ulcerative colitis. Scand J Gastroenterol 1987;22: 214–8.
  • Monsén U, Bernell O, Johansson C, Hellers G. Prevalence of inflammatory bowel disease among relatives of patients with Crohn’s disease. Scand J Gastroenterol 1991;26:302–6.
  • Meucci G, Vecchi M, Torgano G, Arrigoni M, Prada A, Rocca F, et al. Familial aggregation of inflammatory bowel disease in Northern Italy: a multicenter study. Gastroenterology 1992; 103:514–19.
  • Carbonnel F, Macaigne G, Beaugerie L, Gendre JP, Cosnes J. Crohn’s disease severity in familial and sporadic cases. Gut 1999;44:91–9.

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