Treatment of Enterotoxigenic and Enteropathogenic Escherichia coli-induced Diarrhoea in Children with Bovine Immunoglobulin Milk Concentrate from Hyperimmunized Cows: A Double-blind, Placebo-controlled, Clinical Trial

References

• Stoll BJ, Glass RI, Huq MI, Khan MU, Holt JE, Banu H. Surveillance of patients attending a diarrhoeal disease hospital in Bangladesh. Br Med J 1982;285:1185–8.
   PubMed Web of Science ®Google Scholar
• Hoque SS, Faruque AS, Mahalanabis D, Hasnat A. Infectious agents causing watery diarrhoea in infants and young children in Bangladesh and their public health implications. J Trop Pediatr 1994;40:351–4.
   PubMed Web of Science ®Google Scholar
• Levine MM, Edelman R. Enteropathogenic Escherichia coli of classic serotypes associated with infant diarrhea: epidemiology and pathogenesis. Epidemiol Rev 1984;6:31–51.
   PubMed Web of Science ®Google Scholar
• Levine MM. Escherichia coli that causes diarrhoea: enterotoxigenic, enteropathogenic, enteroinvasive, enterohemorrhagic, and enteroadherent. J Infect Dis 1987;155:377–89.
   PubMed Web of Science ®Google Scholar
• Roy SK, Behrens RH, Haider R, Akramuzzaman SM, Mahalanabis D, Wahed MA, et al. Impact of zinc supplementation on intestinal permeability in Bangladeshi children with acute diarrhoea and persistent diarrhoea syndrome. J Pediatr Gastroenterol Nutr 1992;15:289–96.
   PubMed Web of Science ®Google Scholar
• Black RE. Epidemiology of traveler’s diarrhea and relative importance of various pathogens. Rev Infect Dis 1990;12 Suppl 1:S73–9.
   PubMedGoogle Scholar
• Nataro JP, Kaper JB. Diarrheagenic Escherichia coli. Clin Microbiol Rev 1998;11:142–201.
   PubMed Web of Science ®Google Scholar
• Baldwin TJ, Ward W, Aitken A, Knutton S, Williams PH. Elevation of intracellular free calcium levels in HEp-2 cells infected with enteropathogenic Escherichia coli. Infect Immun 1991;59: 1599–604.
   PubMed Web of Science ®Google Scholar
• Kenny B, Finlay BB. Intimin-dependent binding of enteropathogenic Escherichia coli to host cells triggers novel signaling events, including tyrosine phosphorylation of phospholipase C-γ1. Infect Immun 1997;65:2528–36.
   PubMed Web of Science ®Google Scholar
• Honoria-Franca AC, Carvalho MPSM, Isaac L, Trabulsi LR, Carneiro-Sampaio MMS. Colostral mononuclear phagocytes are able to kill Enteropathogenic Escherichia coli opsonized with colostral IgA. Scand J Immunol 1997;46:59–66.
   Google Scholar
• Brüssow H, Hilpert H, Walther I, Sidoti G, Mietens C, Bachmann P. Bovine milk immunoglobulin for passive immunity to infantile rotavirus gastroenteritis. J Clin Microbiol 1987;25:982–6.
   Google Scholar
• Hilpert H, Brüssow H, Mietens C, Sidoti J, Lerner L, Werchau H. Use of bovine milk concentrate containing antibody to rotavirus to treat rotavirus gastroenteritis in infants. J Infect Dis 1987;156:158–66.
   PubMed Web of Science ®Google Scholar
• Huppertz HI, Rutkowski S, Busch DH, Eisebit R, Lissner R, Karch H. Bovine colostrum ameliorates diarrhea in infection with diarrheagenic Escherichia coli, Shiga toxin-producing E-coli, and E-coli expressing intimin and hemolysin. J Pediatr Gastroenterol Nutr 1999;29:452–6.
   PubMed Web of Science ®Google Scholar
• Ebina T, Sato A, Umezu K, Ishida N, Ohyama A, Oizumi A, et al. Prevention of rotavirus infection by oral administration of cow colostrum containing antihuman rotavirus antibody. Med Microbiol Immunol 1985;174:177–85.
   PubMed Web of Science ®Google Scholar
• Mietens C, Keinhorst H, Hilpert H, Garber H, Amster H, Pahud JJ. Treatment of infantile E. coli gastroenteritis with specific bovine anti-E. coli milk immunoglobulins. Eur J Pediatr 1979; 132:239–52.
   PubMed Web of Science ®Google Scholar
• Tacket CO, Losonsky G, Link H, Hoang Y, Guesry P, Hilpert H, et al. Protection by milk immunoglobulin concentrate against oral challenge with enterotoxigenic Escherichia coli. N Engl J Med 1988;318:1240–3.
   PubMed Web of Science ®Google Scholar
• Sarker SA, Casswall TH, Alam NH, Barhdan PK, Mahanalabis D, Hammarström L. Successful treatment of rotavirus diarrhoea in children with immunoglobulins from hyperimmune bovine colostrum: a randomised, double-blind, placebo-controlled trial. Pediatr Infect Dis J 1998;17:1149–54.
   Google Scholar
• Tzipori S, Roberton D, Cooper DA, White L. Chronic cryptosporidial diarrhoea and hyperimmune cow colostrum. Lancet 1987;2:344–5.
   PubMed Web of Science ®Google Scholar
• Freedman DJ, Tacket CO, Delehanty A, Maneval DR, Nataro J, Crabb JH. Milk immunoglobulin with specific activity against purified colonization factor antigens can protect against oral challenge with Enterotoxigenic Escherichia coli. J Infect Dis 1998;177:662–7.
   PubMed Web of Science ®Google Scholar
• Brunser O, Espinoza J, Figueroa G, Araya M, Spencer E, Hilpert H, et al. Field trial of an infant formula containing anti-rotavirus and anti-Escherichia coli milk antibodies from hyperimmunized cows. J Pediatr Gastroenterol Nutr 1992;15:63–72.
   PubMed Web of Science ®Google Scholar
• Mitra AK, Mahalanabis D, Ashraf H, Unicomb L, Eeckles R, Tzipori S. Hyperimmune cow colostrum reduces diarrhoea due to rotavirus: a double-blind, controlled clinical trial. Acta Paediatr 1995;84:996–1001.
   PubMed Web of Science ®Google Scholar
• Lodinovà-Zàdnikovà R, Korych B, Bartàkova Z. Treatment of gastrointestinal infection in infants by oral administration of colostral antibodies. Die Narhung 1987;31:465–7.
   Google Scholar
• Albert MJ, Faruque SM, Faruque AS, Neogi PKB, Ansaruzza-man M, Bhuiyan NA, et al. Controlled study of Escherichia coli diarrheal infections in Bangladeshi children. J Clin Microbiol 1995;33:973–7.
   Google Scholar
• Faruque SM, Haider K, Albert MJ, Ahmad QS, Alam AN, Nahar S, et al. A comparative study of specific gene probes and standard bioassays to identify diarrhoeagenic Escherichia coli in paediatric patients with diarrhoea in Bangladesh. J Med Microbiol 1992;36:37–40.
   PubMed Web of Science ®Google Scholar
• Karlsson K, Granström M, Lindberg AA. Salmonella sp. antibodies. In: Bergmeyer HW, editor. Antigens and antibodies 2. Deerfield Beach: Verlag Chemie; 1986. p. 85–98.
   Google Scholar
• Jansson PE, Lindberg A, Lindberg B, Wollin R. Structural studies on the hexose region of the core in lipopolysaccharides from Enterobacteriaceae. Eur J Biochem 1981;115:571–7.
   PubMedGoogle Scholar
• Westphal O, Lüderitz O, Bister F. Über die extraction von bakterien mit phenol/wasser. Naturforsch 1952;7:148–55.
   Web of Science ®Google Scholar
• Black RE, Brown KH, Becker S, Alim AR, Huq I. Longitudinal studies of infectious diseases and physical growth of children in rural Bangladesh. II. Incidence of diarrhea and association with known pathogens. Am J Epidemiol 1982;115:315–24.
   Google Scholar
• Holmgren J. Mucosal immunity and vaccination. FEMS Microbiol Immunol 1991;89:1–10.
   Google Scholar
• Delneri MT, Carbonare SB, Silva MLM, Palmeira P, Carneiro-Sampaio MMS. Inhibition of enteropathogenic Escherichia coli adhesion to HEp-2 cells by colostrum and milk from mothers delivering low-birth weight neonates. Eur J Pediatr 1997;156: 493–8.
   Google Scholar
• Loureiro I, Frankel G, Adu-Bobie J, Dougan G, Trabulsi LR, Caneiro-Sampaio MMS. Human colostrum contains IgA antibodies reactive to enteropathogenic Escherichia coli virulence-associated proteins: Intimin, BfpA, EspA, and EspB. J Pediatr Gastroenterol Nutr 1998;27: 166–71.
   Google Scholar
• Nomoto K, Matsuoka Y, Hayakawa K, Ohwaki M, Kan T, Yoshikai Y, et al. Antibacterial effect of bovine milk antibody against Escherichia coli in a mouse indigenous infection model. Med Microbiol Immunol 1992;181:87–98.
   PubMed Web of Science ®Google Scholar
• Moyenuddin M, Rahman KM. Enteropathogenic Escherichia coli diarrhea in hospitalized children in Bangladesh. J Clin Microbiol 1985;22:838–40.
   PubMed Web of Science ®Google Scholar
• McClead RE, Butler T, Rabbani GH. Orally administered bovine colostral anti-cholera toxin antibodies: results of two clinical trials. Am J Med 1988;85:811–6.
   Google Scholar
• Apter FM, Michetti P, Winner L Sr, Mack JA, Mekalanos JJ, Neutra MR. Analysis of the role of anti-lipopolysaccharide and anti-cholera toxin immunoglobulin A (IgA) antibodies in protection against Vibrio choleræ and cholera toxin by use of monoclonal IgA antibodies in vivo. Infect Immun 1993;61: 5279–85.
   PubMed Web of Science ®Google Scholar
• Kaper JB. Molecular pathogenesis of enteropathogenic Escherichia coli. In: Millen V, Kapen J, Portney D, editors. Molecular genetics of bacterial pathogenesis. Washington, DC: ASM Press; 1994. p. 173–95.
   Google Scholar
• Zinkernagel RM, Hilpert H, Gerber H. The digestion ofcolostral bovine immunoglobulins in infants. Experientia 1972;28:741.
   Google Scholar
• Blum PM, Phelps DL, Ank BJ, Krantman HJ, Stiehm ER. Survival of oral human serum globulin in the gastrointestinal tract of low birth weight infants. Pediatr Res 1981;15:1256–60.
   Google Scholar
• Losonsky G, Johnson J, Winkelstein J, Yolken R. Oral administration of human serum immunoglobulin in immunodeficient patients with viral gastroenteritis. A pharmacokinetic and functional analysis. J Clin Invest 1985;76:2362–7.
   Google Scholar
• Carbonare SB, Silva MLM, Palmeira P, Carneiro-Sampaio MMS. Human colostral IgA antibodies reacting to enteroparhogenic Escherichia coli antigen and their persistence in faeces of a breastfed infant. J Diarrhoeal Dis Res 1997;15:53–8.
   Google Scholar