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Scandinavian Journal of Gastroenterology Volume 35, 2000 - Issue 4
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Research Article

Diagnosis of Helicobacter pylori Infection in Children: Is the 15N Urine Test More Reliable Than the 13C Breath Test?

P. Krumbiegel Dept. of Human Exposure Research and Epidemiology, UFZ Centre for Environmental Research Leipzig-Halle, Permoserstr. 15, D-04318 Leipzig, Germany
Pages 353-358 | Published online: 08 Jul 2009

References

  • References
  • Graham DY, Klein PD, Evans DJ Jr, Alpert IC, Opekun AP, Boutton TW. Campylobacter pylori detected noninvasively by the 13C-urea test. Lancet 1987; 1: 1174–7.
  • Shreeve WW, Shoop JD, Ott DG, McInteer BB. Test for alcoholic cirrhosis by conversion of 14C or 13C galactose to expired CO2. Gastroenterology 1976; 71: 98–101.
  • Jäger-Roman E, Rating D, Platzek T, Helge H. Development of N-demethylase activity measured with the 13C-aminopyrine breath test. Eur J Pediatr 1982; 139: 129–34.
  • Krumbiegel P, Herbarth O, Fritz G, Schlink U, Gutsmuths F-J, Kindler A, et al. Helicobacter pylori prevalence of the Leipzig birth cohort 1991/92. Design of an environmental-epidemiologic study and first results. Int J Hyg Environ Health 2000; 203.
  • Krumbiegel P, Faust H, Teichmann B, Spencker F-B, Rogos R. Rapid non-invasive diagnosis of gastric Campylobacter pylori infection by a simple [13N2]urea urine test. Nucl Med 1991; 27 Suppl: 262–4.
  • Krumbiegel P, Richter Th, Steinert C, Rettner E, Leicht C, Müller D. Standardization of the [15N2]urea test method to detect antral Helicobacter pylori colonization. Isotopes Environ Health Stud 1997; 33: 177–87.
  • Richter Th, Leicht Ch, Handrick W, Kehrer U, Krumbiegel P. Helicobacter pylori-Infektion im Kindesalter. Diagnostik und Therapiekontrolle mit dem [15N2]Harnstoff-Urintest [abstract]. Monatsschr Kinderheilkd 1996; 144: 483.
  • Krumbiegel P, Günther K, Faust H, Moebius G, Hirschberg K, Schneider G. Nuclear medicine liver function tests for pregnant women and children. I. Breath tests with [14C]methacetin and [13C]methacetin. II. A new test method via urine using [15N]-methacetin. Eur J Nucl Med 1985; 10: 129–33 and 11: 58–61.
  • Krumbiegel P Stable isotope pharmaceuticals. Jena: G. Fischer Verlag; 1991. p. 60–63, 72–73.
  • Krumbiegel P. Stabilisotope Arzneimttel. Habilitation thesis, University of Leipzig, 1986. Zfl Mittl (Leipzig) 1986; 118: 70–3.
  • Rating D, Langhans CD. Breath tests: concepts, applications and limitations. Eur J Pediatr 1997; 156 Suppl 1: S18–23.
  • Guimber D, Chelimsky G, Gottrand F, Czinn S. The year Helicobacter pylori 1999: paediatrics. Curr Opin Gastroenterol 1999; 15 Suppl 1: S49–52.

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