Differential Expression of Gastrin, Cholecystokinin-A and Cholecystokinin-B Receptor mRNA in Human Pancreatic Cancer Cell Lines

References

• Wank S, Harkins R, Jensen RT, Shapira H, de Weerth A, Slattery T. Purification, molecular cloning, and functional expression of the cholecystokinin receptor from rat pancreas. Proc Natl Acad Sci USA 1992;89:3125–9.
   PubMed Web of Science ®Google Scholar
• Wank S, Pisegna J, de Weerth A. Brain and gastrointestinal cholecystokinin receptor family: structure and functional expression. Proc Natl Acad Sci USA 1992;98:8691–5.
   Google Scholar
• Pisegna J, de Weerth A, Huppi K, Wank S. Molecular cloning of the human brain and gastric cholecystokinin receptor: structure, functional expression and chromosomal localisation. Biochem Biophys Res Commun 1992;189:296–303.
   PubMed Web of Science ®Google Scholar
• De Weerth A, Pisegna J, Huppi K, Wank S. Molecular cloning, functional expression and chromosomal localisation of the human cholecystokinin type A receptor. Biochem Biophys Res Commun 1993;811–8.
   PubMedGoogle Scholar
• Monstein H-J, Nylander A-G, Salehi A, Chen D, Lundquist I, Håkanson R. Cholecystokinin-A and cholecystokinin-B/gastrin receptor mRNA expression in the gastrointestinal tract and pancreas of the rat and man. A polymerase chain reaction study. Scand J Gastroenterol 1996;31:383–90.
   Google Scholar
• Walsh JH. Gastrointestinal hormones. In: Johnson LR, editor. Physiology of the gastrointestinal tract. New York: Raven Press; 1994. p. 1–67.
   Google Scholar
• Johnson LR, McCormack SA. Regulation of gastrointestinal mucosal growth. In: Johnson LR, editor. Physiology of the gastrointestinal tract. New York: Raven Press; 1994. p. 611–41.
   Google Scholar
• Håkanson R, Blom H, Carlsson E, Larsson H, Rydberg B, Sundler F. Hypergastrinemia produces trophic effects in stomach but not in pancreas and intestines. Regul Pept 1986;13:225–33.
   Google Scholar
• Håkanson R, Axelson J, Ekman R, Sundler F. Hypergastrinemia evoked by omeprazol stimulates growth of gastric mucosa butnot of pancreas or intestines in hamster, guinea pig and chicken. Regul Pept 1988;23:105–15.
   Google Scholar
• Miller LJ. Does the human pancreas have a type A or B personality? Gastroenterology 1996;111:1767–9.
   PubMedGoogle Scholar
• Wank S, Pisegna JR, de Weerth A. Cholecystokinin receptor family: molecular cloning structure, and functional expression in rat, guinea pig, and human. Ann NY Acad Sci 1994;713:49–66.
   Google Scholar
• Nishimori I, Kamakura M, Hujikawa-Adachi K, Nojima M, Onishi S, Hollingsworth MA, et al. Cholecystokinin A and B receptor mRNA expression in human pancreas. Pancreas 1999;19:109–13.
   Google Scholar
• Weinberg DS, Ruggeri B, Barber MT, Biswas S, Miknyocki S, Waldman SA. Cholecystokinin A and B receptors are differentially expressed in normal pancreas and pancreatic adenocarcinoma. J Clin Invest 1997;100:597–603.
   PubMedGoogle Scholar
• Moonka R, Zhou W, Bell RH. Cholecystokinin-A receptor mRNA expression in human pancreatic cancer. J Gastroenterol Surg 1999;3:134–40.
   Google Scholar
• Herrington MK, Adrian TE. On the role of cholecystokinin in pancreatic cancer. Int J Pancreatol 1995;17:121–38.
   PubMedGoogle Scholar
• Smith JP, Kramer ST, Solomon TE. CCK stimulates the growth of six human pancreatic cancer cell lines in serum free medium. Regul Pept 1991;32:341–9.
   Google Scholar
• Hudd C, LaRegina MC, Devine JE. Response to exogenous cholecystokinin of six human gastrointestinal cancers xeno- grafted in nude mice. Am J Surg 1989;157:386–94.
   Google Scholar
• Smith JP, Rickabaugh CA, McLaughlin PJ, Zagon IS. Cholecystokinin receptors and PANC-1 human pancreatic cancer cells. Am J Physiol 1993;265:G149–55.
   Google Scholar
• Smith JP, Soundararajan V, McLaughlin PJ, Zagon IS. Identification and characterisation of CCK-B/gastrin receptors in human pancreatic cancer cell lines. Am J Physiol 1994;266: R277–83.
   PubMed Web of Science ®Google Scholar
• Smith JP, Hamoroy MW, Verderame MF, Zagon IS. Quantitative analysis of gastrin mRNA and peptide in normal and cancerous human pancreas. Int J Molec Med 1998;2:309–15.
   PubMedGoogle Scholar
• Smith JP, Shih A, Wu Y, McLaughlin PJ, Zagon IS. Gastrin regulates growth of human pancreatic cancer in a tonic and autocrine fashion. Am J Physiol 1996;270:R1078–84.
   Google Scholar
• Iwase K, Evers MB, Hellmich MR, Gou Y-S, Higashide S, Kim HJ, et al. Regulation of growth of human gastric cancer by gastrin and glycine-extended progastrin. Gastroenterology 1997;113:782–90.
   Google Scholar
• Hoosein NM, Kiener PA, Curry RC, Rovati LC, McGilbra DK, Brattin MG. Antiproliferative effects of gastrin receptor antagonists and antibodies to gastrin on human colon carcinoma cell lines. Cancer Res 1998;48:7179–83.
   Google Scholar
• Smith JP, Solomon TE, Bagheri S, Kramer S. Cholecystokonin stimulates growth of human pancreatic adenocarcinoma SW 1990. Dig Dis Sci 1990;35:1377–84.
   PubMedGoogle Scholar
• Smith JP, Fantaskey AP, Liu G, Zagon IS. Identification of gastrin as a growth promoting peptide in human pancreatic cancer. Am J Physiol 1995;268:R135–41.
   PubMed Web of Science ®Google Scholar
• Smith JP, Verderame MF, Zagon IS. Antisense oligonucleotides to gastrin inhibit growth of human pancreatic cancer. Cancer Lett 1999;135:107–12.
   Google Scholar
• Ohlsson B, Fredang N, Axelson J. The effect of bombesin, cholecystokinin, gastrin, and their antagonists on proliferation of pancreatic cancer cell lines. Scand J Gastroenterol 1999;34:1224–9.
   Google Scholar
• Wiborg O, Berglund L, Boel E, Norris F, Norris K, Rehfeld JF, et al. Structure of a human gastrin gene. Proc Natl Acad Sci USA 1984;81:1067–9.
   PubMed Web of Science ®Google Scholar
• Rehfeld JF. Accurate measurement of cholecystokinin in plasma. Clin Chem 1998;44:991–1001.
   PubMed Web of Science ®Google Scholar
• Paloheimo LI, Rehfeld JF. A processing-independent assay of human procholecystokinin and its products. Clin Chem Acta 1994;229:49–65.
   PubMedGoogle Scholar
• Rehfeld JF, Stadil R, Rubin B. Production and evaluation of antibodies for the radioimmunoassay of gastrin. Scand J Clin Lab Invest 1972;30:221–32.
   PubMed Web of Science ®Google Scholar
• Bardram L, Rehfeld JF. Processing-independent radioimmuno- analysis: a general analytical principle applied to progastrin and its products. Anal Biochem 1988;175:537–43.
   PubMed Web of Science ®Google Scholar
• Monstein H-J, Nilsson I, Ellnebo-Svedlund K, Svensson SPS. Cloning and characterisation of 5′-end alternatively spliced human cholecystokinin-B receptor mRNAs. Recept Channels 1998;6: 165–77.
   Google Scholar
• Kaufmann R, Schafberg H, Rudroff C, Henklein P, Nowak G. Cholecystokinin B-type receptor signaling is involved in human pancreatic cancer cell growth. Neuropeptides 1997;31:573–83.
   Google Scholar
• Poston GJ, Gillepsie J, Goillou PJ. Biology of pancreatic cancer. Gut 1991;32:800–12.
   PubMed Web of Science ®Google Scholar
• Goetze JP, Nielsen FC, Burcharth F, Rehfeld JF. Closing the gastrin loop in pancreatic cancer: co-expression of gastrin and its receptor in solid human pancreatic adenocarcinomas. Cancer 2000;88:2487–94.
   PubMed Web of Science ®Google Scholar
• Thumwood CM, Hong JI, Baldwin GS. Inhibition of cell proliferation by the cholecystokinin antagonist L-364, 718. Exp Cell Res 1991;192: 189–92.
   Google Scholar
• Bold RJ, Ishizuka J, Townsend CM Jr, Thompson JC. Gastrin stimulates growth of human colon cancer cells via a receptor other than CCK-A or CCK-B. Biochem Biophys Res Commun 1994;202:1222–6.
   PubMedGoogle Scholar
• Singh P, Owlia A, Espeijo R, Dai B. Novel gastrin receptors mediate mitogenic effects of gastrin and processing intermediates of gastrin on Swiss 3T3 fibroblasts. Absence of detectable cholecystokinin (CCK)-A and CCK-B receptors. J Biol Chem 1995;270:8429–38.
   Google Scholar
• Song I, Brown DR, Wiltshire RN, Gantz I, Trent IM, Yamada T. The human gastrin/cholecystokinin type B receptor gene: alternative splice donor sites in exon 4 generates two variant mRNAs. Proc Natl Acad Sci USA 1993;90:9085–9.
   PubMed Web of Science ®Google Scholar
• Miyake A. A truncated isoform of human CCK-B/gastrin receptor generated by alternative usage of a novel exon. Biochem Biophys Res Commun 1995;208:230–7.
   PubMed Web of Science ®Google Scholar
• Singh P, Dai B, Wiu H, Owlia A. Role of autocrine and endocrine gastrin-like peptides in colonic carcinogenesis. Curr Opin Gastroenterol 2000;16:68–77.
   PubMedGoogle Scholar
• Bestervelt L, Barr B, Dethloff L. Divergent proliferative responses to a gastrin receptor ligand in synchronized and unsynchronized rat pancreatic AR42J tumour cells. Cell Signal 2000;12: 53–61.
   Google Scholar
• Detjen K, Fenrich MC, Logsdon CD. Transfected cholecysto- kinin receptors mediate growth inhibitory effects on human pancreatic cancer cell lines. Gastroenterology 1997;112:952–9.
   Google Scholar
• Robertson JFR, Watson SA, Hardcastle JD. Effect of gastrointestinal hormones and synthetic analogues on the growth of pancreatic cancer. Int J Cancer 1995;63:69–75.
   Google Scholar
• Reubi JC, Schaer J-C, Waser B. Cholecystokinin (CCK)-A and CCK-B/Gastrin receptors in human tumours. Cancer Res 1997; 57:1377–86.
   Google Scholar
• Bardram L. Gastrin in non-neoplastic pancreatic tissue from patients with and without gastrinomas. Scand J Gastroenterol 1990;25:935–43.
   PubMed Web of Science ®Google Scholar
• Wang RN, Rehfeld JF, Nielsen FC, Klöppel G. Expression of gastrin mRNA and transforming growth factor- α during duct to islet cell differentiation in the pancreas of duct ligated adult rats. Diabetologia 1997;40:887–93.
   Google Scholar