27
Views
8
CrossRef citations to date
0
Altmetric
Research Article

Genetic Basis of Chronic Pancreatitis

, , &
Pages 91-94 | Published online: 08 Jul 2009

References

  • Ammann RW, Muellhaupt B, and Zurich Pancreatitis Study Group. The natural history of pain in alcoholic chronic pancreatitis. Gastroenterology 1999;116:1132–40.
  • Lankisch PG, Loerh-Happe A, Otto J, Creutzfeldt W. Naturlicher Verlauf der chronischen Pancreatitis-Schmerz, exokrine und endokrine pancreas insufficienz und Prognose de Erkrankung. Zentralbl Chir 1995;120:278–86.
  • Ammann RW. A clinically based classification system for alcoholic chronic pancreatitis : summary of an international workshop on chronic pancreatitis. Pancreas 1997;14:215–22.
  • Whitcomb DC, Gorry MC, Preston RA, Furey W, Sossenheimer MJ, Ulrich CD. Hereditary pancreatiti s is caused by a mutation in the cationic trypsinogen gene. Nat Genet 1996;14:141–5.
  • Chiari H. Ueber Selbstverdauung des Menschlichen Pankreas. Z Heilkunde 1896;17:69–96.
  • Sossenheimer MJ, Aston CE, Preston RA, et al. Clinical characteristics of hereditary pancreatitis in a large family, based on high risk haplotype. Am J Gastroenterol 1997;92:1113–6.
  • Whitcomb DC, Prestron RA, Aston CE, et al. A gene for hereditary pancreatitis maps to chromosome 7q35. Gastroenterology 1996;110;1975–80.
  • Le Bodic L, Bignon JD, Raguenes O, et al. The hereditary pancreatiti s gene maps to long arm of chromosome 7. Hum Mol Genet 1996;5:549–54.
  • Rowen L, Koop BF, Hood L, et al. The complete 685 kilo-base DNA sequence of the human beta T-cell locus. Science 1996; 272:1755–62.
  • Antonarakis SE and the Nomenclature Workgroup. Recommendations for a nomenclature system for human gene mutations. Hum Mutat 1998;11:1–3.
  • Rinderknecht H. Activation of pancreatic zymogens. Normal activation, premature intrapancreati c activation, protective mechanisms against inappropriate activation. Dig Dis Sci 1986;31:314–21.
  • Steer ML. The early intraacinar cell events which occur during acute pancreatitis [Frank Brooks memorial lecture]. Pancreas 1998;17:31–7.
  • Colomb E, Figarella C, Guy O. The two human trypsinogens. Evidence of complex formation with basic pancreatic trypsin inhibitor-proteolytic activity. Biochim Biophys Acta 1979;570: 397–405.
  • Guy-Crotte O, Miszczuk-Jamska B, Brayle A, et al. Monoclonal antibodies to human pancreatic trypsin-1 inhibit the activation of human trypsinogens 1 and 2. Eur J Biochem 1992;204:133–6.
  • Sahin-Toth M, Graf L, Toth M. Trypsinogen stabilization by mutation Arg117-His: a unifying pathomechanism for hereditary pancreatitis? Biochem Biophys Res Commun 1999;264: 505–8.
  • Sahin-Toth M. Hereditary pancreatitis-associated mutation asn(21)-ile stabilizes rat trypsinogen in vitro. J Biol Chem 1999; 274:29699–704.
  • Witt H, Luck W, Becker M. A signal peptide cleavage site mutation in the cationic trypsingen gene is strongly associated with chronic pancreatitis. Gastroenterology 1999;117:7–10.
  • Ferec C, Raguenes O, Salomon R, et al. Mutations in the cationic trypsinogen gene and evidence for genetic heterogeneity in hereditary pancreatitis. J Med Genet 1999;36:228–32.
  • Raguenes O, Deprez P, Verellen Ch, et al. Mutational screening of the cationic trypsinogen gene in a large cohort of patients with sporadic chronic pancreatitis reveals novel DNA variants. Am J Hum Genet 1999;65:A486.
  • Witt H, Luck W, Hennies HC, et al. Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis. Nat Genet 2000;25:213–6.
  • Drenth JPH, Te Morsche R, Gunenc T, Jansen JBMJ. A single mutation in serine protease inhibitor Kazal type 1 is strongly associated with chronic pancreatitis. In press.
  • Worning H. Chronic pancreatitis; pathogenesis, natural history and conservative treatment. Clin Gastroenterol 1984;13:871–94.
  • Cohn JA, Friedman KJ, Noone PG, et al. Relation between mutations in the cystic fibrosis gene and idiopathic pancreatitis. N Engl J Med 1998;339:653–8.
  • Sharer N, Schwarz M, Malone G, et al. Mutations of the cystic fibrosis gene in patients with chronic pancreatitis. N Engl J Med 1998;339:645–52.
  • Malats N, Casals T, Porta M, et al. Cystic fibrosis transmembrane regulator (CFTR) deltaF508 mutation and 5T allele in patients with chronic pancreatitis and exocrine pancreatic cancer. Gut 2001;48:70–4
  • Kimura S, Okabayashi Y, Inushima K, et al. Alcohol and aldehyde dehydrogenase polymorphisms in Japanese patients with alcohol-induced chronic pancreatitis. Dig Dis Sci 2000; 45:2013–17.
  • Ruthenbuerger M, Krueger B, Halangk W, et al. Intracellular pro-elastase but not trypsinogen activation is associated with acinar cell injury. Pancreas 2000;21:A474.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.