19
Views
4
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE: Liver and Biliary Tract

Reduction of CD45RA Isoform Expression and Decrease in CD4 and CD8 Receptor Density in Lymphocytes of Patients with Primary Biliary Cirrhosis

, , , , , & show all
Pages 421-426 | Received 26 Sep 2002, Accepted 24 Dec 2002, Published online: 27 Feb 2017

References

  • Coppel R, Gershwin M. Primary biliary cirrhosis: the molecule and the mimic. Immunol Rev 1995; 144: 17–49.
  • Mackay I, Gershwin E. The nature of autoimmune disease. Semin Liver Dis 1997; 17: 3–12.
  • Laurin J, Lindor K. Primary biliary cirrhosis. Dig Dis 1994; 12: 331–50.
  • Nakanuma Y, Tsuneyama K, Gershwin, Yasoshima M. Pathology and immunopathology of primary biliary cirrhosis with emphasis on bile duct lesions: recent progress. Semin Liver Dis 1995; 15: 313–28.
  • Bassendine M, Jones D, Yeaman S. Biochemistry and autoimmune response to the 2-Oxoacid dehydrogenase complexes in primary biliary cirrhosis. Semin Liver Dis 1997; 17: 49–60.
  • Leung P, Coppel R, Ansari A, Munoz S, Gershwin M. Antimitochondrial antibodies in primary biliary cirrhosis. Semin Liver Dis 1997; 17: 61–9.
  • Bjorkland A, Festin R, Mendel-Hartvig, Nyberg A, Loof L, Totterman T. Blood and liver-infiltrating lymphocytes in primary biliary cirrhosis: increase in activated T and natural killer cells and recruitment of primed memory T cells. Hepatology 1991; 13: 1106–11.
  • Leon M, Spickett G, Jones D, Bassendine M. CD4+ T cell subsets defined by isoforms of CD45 in primary biliary cirrhosis. Clin Exp Immunol 1995; 99: 233–9.
  • Li X, Jeffers L, Reddy K. Immunophenotyping of lymphocytes in liver tissue of patients with chronic liver diseases by flow cytometry. Hepatology 1991; 14: 121–7.
  • Bell E, Sparshott S, Bince C. CD4+ T-cell memory, CD45R subsets and the persistence of antigen: a unifying concept. Immunol Today 1998; 19: 60–4.
  • Akbar A, Terry L, Timms A, Beverley P, Janossy G. Loss of CD45 and gain of UCHL-1 reactivity is a feature of primed T cells. J Immunol 1998; 140: 2171–8.
  • Dohlsten M, Sjogren H, Carlsson R. Two subsets of human CD4+ T helper cells differing in kinetics and capacities to produce interleukin-2 and interferon-gamma can be defined by the Leu-18 and UCHL-1 monoclonal antibodies. Eur J Immunol 1988; 18: 1173–8.
  • Smith S, Brown M, Rowe D, Callard R, Beverley P. Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL 1. Immunology 1986; 58: 63–70.
  • Marimoto C, Letvin N, Distaso J, Aldrich W, Schlossman S. The isolation and characterisation of the human supressor-inducer T cell subset. J Immunol 1988; 134: 1508–14.
  • Mackall C, Hakim, Grees R. T-cell regeneration: all repertoires are not created equal. Immunol Today 1997; 18: 245–51.
  • Valiante N, Trichieri G. Identification of a novel signal transduction surface molecule on human cytotoxic lymphocytes. J Exp Med 1993; 178: 1397–406.
  • Schmid I, Schmid P, Giorgi J. Conversion of logarithmic channel numbers into relative linear fluorescence intensity. Cytometry 1988; 9: 533–8.
  • He X, Rehermann B, Boisvert J, Mumm J, Maecker H, Roederer M, et al. Direct functional analysis of epitope-specific CD8+ T cells in peripheral blood. Viral Immunol 2001; 14: 59–69.
  • Sobel R, Hafler D, Castro É, Morimoto C, Weiner H. The 2H4 (CD45R) antigen is selectively decreased in multiple sclerosis lesions. J Immunol 1988; 140: 2210–14.
  • Koch A, Robinson P, Radosevich J, Pope R. Distribution of CD45RA and CD45RO T lymphocyte subset in rheumatoid arthritis synovial tissue. J Clin Immunol 1990; 10: 192–6.
  • Serra H, Mant M, Ruether B, Ledbetter J, Pilarski L. Selective loss of CD4+CD45R+ T cells in peripheral blood of multiple myeloma patients. J Clin Immunol 1988; 8: 259–65.
  • Socha P, Michalkiewicz J, Stachowski J, Pawlowska J, Jankowska I, Barth C, et al. Deficiency of the expression of CD45RA isoform of CD45 common leukocyte antigen in CD4+ T lymphocytes in children with infantile cholestasis. Immunol Lett 2001; 75: 179–84.
  • Czaja A, Homburger H. Autoantibodies in liver disease. Gastroenterology 2001; 120: 239–49.
  • Suzuki I, Fink P. The dual functions of Fas ligand in the regulation of peripheral CD8+ and CD4+ T cells. PNAS 2000; 97: 1707–12.
  • Mehal W, Azzaroli F, Crispe I. Immunology of the healthy liver: old questions and new insights. Gastroenterology 2001; 120: 250–60.
  • Knapp W, Dorken B, Rieber E, Gilks W, Rieber E, Schmidt R, et al. editors. Leucocyte typing IV: White cell differentiation antigens. New York: Oxford University Press; 1989.
  • Sanders M, Makgoba M, Sharrow S, Stephany D, Springer T, Young H, et al. Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA- 3, CD2, and LFA-1) and three other molecules (UCHL-1, CDw29, and Pgp-1) and have enhanced IFN-gamma production. J Immunol 1988; 140: 1401–7.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.