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Editorial

Editorial: The CARD15 gene mutation in Crohn disease

Pages 1105-1106 | Published online: 08 Jul 2009

References

  • Hugot JP, Laurent-Puig P, Gower-Rousseau C, Olson JM, Lee JC, Beaugerie L, et al. Mapping of a susceptibility locus for Crohn’s disease on chromosome 16. Nature 1996;379:821–3.
  • Cavanaugh J. The IBD International Genetic Consortium. International collaboration provides convincing linkage replication in complex disease through analysis of a large pooled data set: Crohn’s disease and chromosome 16. Am J Hum Genet 2001;68: 1165–71.
  • Hampe J, Cuthbert A, Croucher PJ, Muddassar NN, Mascheretti S, Fisher S, et al. Association between insertion mutation in NOD2 gene and Crohn’s disease in German and British populations. Lancet 2001;357:1925–8.
  • Hugot JP, Chamaillard M, Zouali H, Lesage S, Cézard JP, Belaiche J, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn’s disease. Nature 2001;411: 599–603.
  • Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, et al. A frame shift mutation in NOD2 associated with susceptibility to Crohn’s disease. Nature 2001;411:603–6.
  • Hampe J, Grebe J, Nikolaus S, Solberg C, Croucher PJ, Mascheretti S, et al. Association of NOD2 (Card 15) genotype with clinical course of Crohn’s disease: a cohort study. Lancet 2002;359:1661–5.
  • Vermeire S, Wild G, Kocher K, Cousineau J, Dufresne L, Bitton A, et al. NOD2/Card 15 mutations in Crohn’s disease in a Quebec population: prevalence, genotype-phenotype relationship, and haplotype structure. Am J Hum Genet 2002;71:74–83.
  • Crichton DN, Arnott IDR, Watts D, Mowatt C, Hutchinson J, Drummond H, et al. NOD2/CARD15 mutations in a Scottish Crohn’s disease population (#M1420). Gastroenterology. Digestive disease week and the 103rd annual meeting of the American Gastroenterological Association 2002;122:A–298.

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