Anti‐CagA and anti‐VacA antibodies in Helicobacter pylori‐infected patients with and without peptic ulcer disease in Serbia and Montenegro

References

• Hunt RH, Lam SK. Helicobacter pylori: from art to science. J Gastroenterol Hepatol 1998;13:21–8.
   PubMedGoogle Scholar
• Megraud F. Impact of Helicobacter pylori virulence in the outcome of gastroduodenal diseases: lessons from the microbiologist. Dig Dis 2001;19:99–103.
   PubMedGoogle Scholar
• Sande N, Nikulin M, Nilsson I, Wadstrom T, Laxen F, Harkonen M, et al. Increased risk of developing atrophic gastritis in patients infected with CagA+ Helicobacter pylori. Scand J Gastroenterol 2001;36:928–33.
   PubMed Web of Science ®Google Scholar
• Peek RM, Miller GG, Tham KT, Perez-Perez GI, Zhao X, Atherton JC, et al. Heightened inflammatory response and cytokine expression in vivo to CagA+ Helicobacter pylori strains. Lab Invest 1995;73:760–70.
   Google Scholar
• Takata T, Fujimoto S, Anzai K, Shirotani T, Okada M, Sawae Y, et al. Analysis of the expression of cag A and vac A and the vacuolating activity in 167 isolates from patients with either peptic ulcers or non ulcer dyspepsia. Am J Gastroenterol 1998; 93:30–4.
   PubMedGoogle Scholar
• Segal ED, Cha J, Lo J, Falkow S, Tompkins LS. Altered state: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori. Procl Natl Acad Sci USA 1999;96: 14559–64.
   PubMed Web of Science ®Google Scholar
• Crabtree JE, Farmery SM, Lindley IJD, Figura N, Peichl P, Tompkins DS. CagA+ cytotoxic strains of Helicobacter pylori and interleukin 8 in gastric epithelial cell lines. J Clin Pathol 1994;47:945–50.
   PubMed Web of Science ®Google Scholar
• Rudi J, Kolb C, Maiwald M, Kuck D, Sieg A, Galle P, et al. Diversity of Helicobacter pylori VacA and CagA protein expression, cytotoxin production and associated diseases. J Clin Microbiol 1998;36:944–8.
   PubMed Web of Science ®Google Scholar
• Cover TL. The vacuolating cytotoxin of Helicobacter pylori. Mol Microbiol 1996;20:241–6.
   PubMed Web of Science ®Google Scholar
• Atherton JC, Cao P, Peek RM, Tummuru MK, Blaser MJ, Cover TL. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori: association of specific vac A types with cytotoxin production and peptic ulceration. J Biol Chem 1995;270:17771–7.
   PubMed Web of Science ®Google Scholar
• Ghiara P, Marchetti M, Blaser MJ, Tummuru MK, Cover TL, Segal ED, et al. Role of Helicobacter pylori virulence factors vacuolating cytotoxin, cag A, and urease in a mouse model of disease. Infect Immunol 1995;63:4154–60.
   PubMed Web of Science ®Google Scholar
• Cover TL, Cao P, Lind CD, Tham KT, Blaser MJ. Correlation between vacuolisating cytotoxin production by Helicobacter pylori isolates in vitro and in vivo. Infect Immun 1993;61:5008–12.
   Google Scholar
• Supajatura V, Ushio H, Wada A, Yahiro K, Okumura K, Ogawa H, et al. Cutting edge: VacA, a vacuolating cytotoxin of Helicobacter pylori directly activates mast cell for migration and production of proinflammatory cytokines. J Immunol 2002;168: 2603–7.
   PubMed Web of Science ®Google Scholar
• Pai R, Sasaki E, Tarnawski AS. Helicobacter pylori vacuolating cytotoxin alters cytoskeleton associated proteins and interferes with re-epithelization of wounded gastric epithelial monolayers. Cell Biol Int 2000;24:291–301.
   Google Scholar
• Xiang Z, Censini S, Bayeli PF, Telford JL, Figura N, Rappuoli R, et al. Analysis of expression of cag A and vac A virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into 2 major types and that cag A is not necessary for expression of vacuolating cytotoxin. Infect Immun 1995;63: 94–8.
   PubMed Web of Science ®Google Scholar
• Collin-Jones DG. Management of dyspepsia. Report of a working party. Lancet 1988;1:575–9.
   Google Scholar
• Malfertheiner P, Megraud F, O’Morain CO, Bell D, Bianchi Porro G, Deltenre M, et al. Current European concepts in the management of Helicobacter pylori infection: the Maastricht consensus report. Eur J Gastroenterol Hepatol 1997;9: 91–2.
   Google Scholar
• Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis. The updated Sydney System. Am J Surg Pathol 1996;20:1161–81.
   PubMed Web of Science ®Google Scholar
• Wesjnen CF, Hendriks HA, Hoes AW, Verweij WM, Werheij TJM, de Wit NJ. New immunoassay for the detection of Helicobacter pylori infection compared with urease test, 13C test and histology: validation in primary care setting. J Microbiol Meth 2001;46: 235–40.
   Google Scholar
• Carattoli A, Pezzella C, Pitroiust A, Galante A, Pezzotti P, Luzzi I. Cytotoxin-associated gene A and vacuolating cytotoxin A in human isolates of Helicobacter pylori and their association with the clinical status of ulcer disease. Eur J Gastroenterol Hepatol 2000;12:1207–13.
   PubMed Web of Science ®Google Scholar
• Cover TL, Glupczynski Y, Lage AP, Burette A, Tummuru MKR, Perez-Perez GI, et al. Serologic detection of infection with CagA+ Helicobacter pylori strains. J Clin Microbiol 1995;33: 1496–50.
   Google Scholar
• Suadicani P, Hein OH, Gyntelberg F. Genetic and life-style determinants of peptic ulcer. Scand J Gastroenterol Hepatol 1999;34:12–7.
   PubMed Web of Science ®Google Scholar
• Graessle S, Grabher G, Gapp G, Preuss E, Datz C, Sandhofer F, et al. Immune response to natural and recombinant antigens of Helicobacter pylori in patients with dyspeptic complaints. Eur J Clin Microbiol Infect Dis 1999;18:636–42.
   PubMedGoogle Scholar
• Weel JFL, van der Hulst RWM, Gerrits Y, Roorda P, Feller M, Dankert J, et al. The interrelationship between cytotoxin associated geneA, vacuolating cytotoxin and Helicobacter pylori related diseases. J Infect Dis 1996;173:1171–5.
   PubMed Web of Science ®Google Scholar
• Orsini B, Ciancio G, Surrenti E, Macri G, Biagini MR, Milani S, et al. Serologic detection of CagA positive Helicobacter pylori infection in Northern Italian population: its association with peptic ulcer disease. Helicobacter 1998;3:15–20.
   PubMedGoogle Scholar
• Mahachai V, Tangkijvanich P, Wannachai N, Sumpathankul P, Kullavanijaya P. Cag A and vac A: virulence factors of Helicobacter pylori in Thai patients with gastroduodenal diseases. Helicobacter 1999;4: 143–7.
   PubMedGoogle Scholar
• El-Mahdi AM, Patchet S, Char S, Domizio P, Fedail S, Kumar P. Does cag A contribute to ulcer pathogenesis in a developing country, such as Sudan. Eur J Gastroenterol Hepatol 1998; 10: 313–6.
   Google Scholar
• Figura N, Guglielemetti P, Rossolini A. Cytotoxin production by Campylobacter pylori strains isolated from patients with peptic ulcer and from patients with chronic gastritis only. J Clin Microbiol 1989;27:225–6.
   Google Scholar
• Sepulveda AR, Coelho LGV. Helicobacter pylori and gastric malignancies. Helicobacter 2002;7 Suppl 1:37–42.
   PubMed Web of Science ®Google Scholar
• Kuipers EJ, Pena AS, van Kamp G, Uyterlinde AM, Pals G, Pels NFM, et al. Seroconversion for Helicobacter pylori. Lancet 1993;342:328–31.
   PubMed Web of Science ®Google Scholar