Cysteinyl leukotrienes are secretagogues in atrophic coeliac and in normal duodenal mucosa of children

References

• Mohajer B, Ma TY. Eicosanoids and the small intestine. Prostaglandin Lipid Med 2000;61:125–43.
   PubMedGoogle Scholar
• Smith PL, Blumberg JB, Stoff JS, Field M. Antisecretory effects of indomethacin on rabbit ileal mucosa in vitro. Gastroenterology 1981;80:356–65.
   PubMed Web of Science ®Google Scholar
• Van Loon FP, Rabbani GH, Bukhave K, Rask-Madsen J. Indomethacin decreases jejunal fluid secretion in addition to luminal release of prostaglandin E2 in patients with acute cholera. Gut 1992;33: 643–5.
   Google Scholar
• Marsh M. Mucosal pathology in gluten sensitivity. In: Marsh M, editor. Coeliac disease. Oxford: Blackwell Science; 1992. p. 136–91.
   Google Scholar
• Ivarsson A, Persson LA, Juto P, Peltonen M, Suhr O, Hernell O. High prevalence of undiagnosed coeliac disease in adults: a Swedish population-based study. Ann Intern Med 1999;245:63–8.
   Google Scholar
• Reims A, Redfors S, Ascher H, Strandvik B. Electrogenic ion transport in duodenal biopsies from children with coeliac disease. Scand J Gastroenterol 2002;37:43–50.
   PubMed Web of Science ®Google Scholar
• Samuelsson B, Dahlén S-E, Lindgren JÅ, Rouzer CA, Serhan CN. Leukotrienes and lipoxins: structures, biosynthesis and biological effects. Science 1987;237:1171–6.
   PubMed Web of Science ®Google Scholar
• Sala A, Zarini S, Bolla M. Leukotrienes: lipid bioeffectors of inflammatory reactions. Biochemistry 1998;63:84–92.
   Google Scholar
• Feuerstein G. Autonomic pharmacology of leukotrienes. J Auton Pharmacol 1985;5:149–68.
   PubMedGoogle Scholar
• Paruchuri S, Hallberg B, Juhas M, Larsson C, Sjolander A. Leukotriene D4 activates MAPK through a Ras-independent but PKCε-dependent pathway in intestinal epithelial cells. J Cell Sci 2002;115: 1883–93.
   Google Scholar
• Alanko J, Riutta A, Vapaatalo H. Effects of catecholamines on eicosanoid synthesis with special reference to prostanoid/ leukotriene ratio. Free Rad Biol Med 1992;13:677–88.
   Google Scholar
• Branski D, Hurvitz H, Halevi A, Klar A, Navon P, Weidenfeld J. Eicosanoids content in small intestinal mucosa of children with celiac disease. J Pediatr Gastroenterol Nutr 1992;14:173–6.
   PubMedGoogle Scholar
• Shimizu T, Beijer E, Ryd W, Strandvik B. Leukotriene B4 and C4 generation by small intestinal mucosa in children with coeliac disease. Digestion 1994;55:239–42.
   PubMedGoogle Scholar
• Shimizu T, Beijer E, Strandvik B. Leukotriene B4 and C4 metabolism in small intestine mucosa of children with celiac disease. J Pediatr Gastroenterol Nutr 1995;21: 426–9.
   Google Scholar
• Reims A, Redfors S, Hemlin M, Mellander A, Strandvik B. Electrogenic ion transport along the human duodenum in childhood. Scand J Gastroenterol 1997;32:894–9.
   PubMed Web of Science ®Google Scholar
• Hyun CS, Binder HJ. Mechanism of leukotriene D4 stimulation of Cl− secretion in rat distal colon in vitro. Am J Physiol 1993;265:G467–73.
   Google Scholar
• Schaeffer BE, Van Praag D, Greenwald L, Farber SJ, Zadunaisky A. Effects of leukotrienes on chloride transport across frog cornea. In: Braquet P, editor. Prostaglandins and membrane ion transport. New York: Raven Press; 1984. p. 165–72.
   Google Scholar
• Smith PL, Chiossone DC, McCafferty GP. Characterization of LTC4 effects on rabbit ileal mucosa in vitro. Naunyn Schmiedebergs Arch Pharmacol 1990;341: 94–100.
   Google Scholar
• Keppler M. Leukotrienes: biosynthesis, transport, inactivation, and analysis. Rev Physiol Biochem Pharmacol 1992;121:1–30.
   PubMedGoogle Scholar
• Dreyling KW, Hoppe U, Peskar BA, Morgenroth K, Kozuschek W, Peskar BM. Leukotriene synthesis by human gastrointestinal tissues. Biochim Biophys Acta 1986;878:184–93.
   PubMed Web of Science ®Google Scholar
• Jett MF, Marshall P, Fondacaro JD, Smith PL. Action of peptidoleukotrienes on ion transport in rabbit distal colon in vitro. J Pharmacol Exp Ther 1991;257:698–705.
   PubMedGoogle Scholar
• Wardle TD, Hall L, Turnberg LA. Inter-relationships between inflammatory mediators released from colonic mucosa in ulcerative colitis and their effects on colonic secretion. Gut 1993;34:503–8.
   Google Scholar
• Piper PJ, Samhoun MN. Stimulation of arachidonic acid metabolism and generation of thromboxane A2 by leuko- trienes B4, C4 and D4 in guinea-pig lung in vitro. Br J Pharmacol 1982;77:267–75.
   PubMed Web of Science ®Google Scholar
• Crooke ST, Mattern M, Sarau HM, Winkler JD, Balcarek J, Wong A, et al. The signal transduction system of the leukotriene D4 receptor. TiPS 1989;10:103–7.
   PubMedGoogle Scholar
• Abramson SB, Leszczynska-Piziak J, Weissmann G. Arachi- donic acid as a second messenger. J Immunol 1991;147: 231–6.
   PubMedGoogle Scholar
• Barrett KE, Bigby TD. Involvement of arachidonic acid in the chloride secretory response of intestinal epithelial cells. Am J Physiol 1993;264:C446–52.
   Google Scholar
• Sumida C, Graber R, Nunez E. Role of fatty acids in signal transduction: modulators and messengers. Prostaglandins Leukotr Ess Fatty Acids 1993;48:117–22.
   PubMed Web of Science ®Google Scholar
• Wolf BA, Turk J, Sherman WR, McDaniel ML. Intracellular Ca2 + mobilisation by arachidonic acid. J Biol Chem 1986;261:3501–11.
   PubMed Web of Science ®Google Scholar
• Devor DC, Frizzell RA. Modulation of K+ channels by arachidonic acid in T84 cells. II. Activation of a Ca^{2 +} - independentK⁺ channel.AmJPhysiol 1998;274:C149–60.
   Google Scholar
• Keenan CM, Rangachari PK. Contrasting effects of PGE2 and PGD2: ion transport in the canine proximal colon. Am J Physiol Gastrointest Liver Physiol 1991;260: G481–8.
   Google Scholar
• Thodeki CK, Sjölander A. Leukotriene D4-induced calcium signalling in human intestinal epithelial cells. Adv Exp Med Biol 2002;507:187 91.
   Google Scholar
• Wikström K, Öhd JF, Sjölander A. Regulation of leuko- triene-dependent induction of cyclooxygenase-2 and Bcl-2. Biochem Biophys Res Commun 2003;302:330–5.
   PubMedGoogle Scholar
• Shahbazian A, Heinemann A, Peskar BA, Holzer P. Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine. Br J Pharmacol 2002; 137:1047–54.
   PubMedGoogle Scholar
• Hammerbeck DM, Brown DR. Neurally mediated actions of leukotrienes on ion transport in guinea-pig distal colon. J Pharmacol Exp Ther 1993;264:384–90.
   PubMedGoogle Scholar
• Liu S, Hu H-Z, Gao C, Gao N, Wang G, Wang X, et al. Actions of cysteinyl leukotrienes in the enteric nervous system of guinea-pig stomach and small intestine. Eur J Pharmacol 2003;459:27–39.
   Google Scholar