Polaprezinc (N-(3-aminopropionyl)-L-histidinato zinc) ameliorates dextran sulfate sodium-induced colitis in mice

References

• Podolsky DK. Inflammatory bowel disease. N Engl J Med 1991; 325: 928–37
   PubMed Web of Science ®Google Scholar
• Sartor RB. Pathogenesis and immune mechanisms of chronic inflammatory bowel diseases. Am J Gastroenterol 1997; 92 Suppl 12: 5S–11S
   Google Scholar
• Papadakis KA, Targan SR. Role of cytokines in the pathogenesis of inflammatory bowel disease. Annu Rev Med 2000; 51: 289–98
   PubMed Web of Science ®Google Scholar
• de Jong YP, Abadia-Molina AC, Satoskar AR, Clarke K, Rietdijk ST, Faubion WA, et al. Development of chronic colitis is dependent on the cytokine MIF. Nat Immunol 2001; 2: 1061–6
   PubMed Web of Science ®Google Scholar
• Ohkawara T, Nishihira J, Takeda H, Hige S, Kato M, Sugiyama T, et al. Amelioration of dextran sulfate sodium-induced colitis by anti-macrophage migration inhibitory factor antibody in mice. Gastroenterology 2002; 123: 256–70
   PubMed Web of Science ®Google Scholar
• Sands BE. Therapy of inflammatory bowel disease. Gastroenterology 2000; 118: S68–82
   PubMed Web of Science ®Google Scholar
• Yoshikawa T, Naito Y, Tanigawa T, Yoneta T, Kondo M. The antioxidant properties of a novel zinc-carnosine chelete compound, N-(3-aminopropionyl)-L-histidinato zinc. Biochim Biophys Acta 1991; 1115: 15–22
   PubMed Web of Science ®Google Scholar
• Yoshikawa T, Naito Y, Tanigawa T, Yoneta T, Yasuda M, Ueda S, et al. Effect of zinc-carnosine chelate compound (Z-103), a novel antioxidant, on acute gastric mucosal injury induced by ischemia-reperfusion in rats. Free Radic Res Commun 1991; 14: 289–96
   PubMed Web of Science ®Google Scholar
• Handa O, Yoshida N, Tanaka Y, Ueda M, Ishikawa T, Takagi T, et al. Inhibitory effect of polaprezinc on the inflammatory response to Helicobacter pylori. Can J Gastroenterol 2002; 16: 785–9
   PubMed Web of Science ®Google Scholar
• Ishikawa R, Iishi H, Sakai N, Yano H, Ueno N, Narahara H, et al. Polaprezinc attenuates Helicobacter pylori-associated gastritis in Mongolian gerbils. Helicobacter 2002; 7: 384–9
   PubMed Web of Science ®Google Scholar
• Korolkiewicz RP, Fujita A, Seto K, Suzuki K, Takeuchi K. Polaprezinc exerts a salutary effect on impaired healing of acute gastric lesions in diabetic rats. Dig Dis Sci 2000; 45: 1220–9
   Google Scholar
• Ueki S, Seiki M, Yoneta T, Omata T, Hori Y, Ishikawa M, et al. Effect of Z-103 on compound 48/80-induced gastric lesions in rats. Scand J Gastroenterol 1989; 162: 202–5
   Google Scholar
• Takagi H, Nagamine T, Abe T, Takayama H, Sato K, Otsuka T, et al. Zinc supplementation enhances the response to interferon therapy in patients with chronic hepatitis C. J Viral Hepatol 2001; 8: 367–71
   PubMed Web of Science ®Google Scholar
• Yoshikawa T, Yamaguchi T, Yoshida N, Yamamoto H, Kitazumi S, Takahashi S, et al. Effect of Z-103 on TNB-induced colitis in rats. Digestion 1997; 58: 464–8
   PubMed Web of Science ®Google Scholar
• Odashima M, Otaka M, Jin M, Konishi N, Sato T, Kato S, et al. Induction of a 72-kDa heat-shock protein in cultured rat gastric mucosal cells and rat gastric mucosa by zinc L-carnosine. Dig Dis Sci 2002; 47: 2799–804
   PubMed Web of Science ®Google Scholar
• Cooper HS, Murthy SN, Shah RS, Sedergran DJ. Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 1993; 69: 238–49
   PubMed Web of Science ®Google Scholar
• Krawisz JE, Sharon P, Stenson WF. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 1984; 87: 1344–50
   PubMed Web of Science ®Google Scholar
• Sugawara N, Katakura M, Sugawara C. Preventive effect of zinc compounds, polaprezinc and zinc acetate against the onset of hepatitis in Long-Evans Cinnamon rat. Res Commun Mol Pathol Pharmacol 1999; 103: 167–76
   PubMedGoogle Scholar
• Katayama S, Nishikawa K, Hirano M, Yamamura S, Momose Y. Effect of polaprezinc on healing of acetic acid-induced stomatitis in hamsters. J Pharm Pharm Sci 2000; 3: 114–7
   PubMed Web of Science ®Google Scholar
• Medina C, Videla S, Radomski A, Radomski M, Antolin M, Guarner F, et al. Therapeutic effect of phenantroline in two rat models of inflammatory bowel disease. Scand J Gastroenterol 2001; 36: 1314–9
   PubMed Web of Science ®Google Scholar
• Chen BW, Wang HH, Liu JX, Liu AG. Zinc sulphate solution enema decreases inflammation in experimental colitis in rats. J Gastroenterol Hepatol 1999; 14: 1088–92
   PubMed Web of Science ®Google Scholar
• Luk HH, Ko JKS, Fung HS, Cho CH. Delineation of the protective action of zinc sulfate on ulcerative colitis in rats. Eur J Pharmacol 2002; 443: 197–204
   PubMed Web of Science ®Google Scholar
• Sturniolo GC, Fries W, Mazzon E, Leo VD, Barollo M, D'Inca R. Effect of zinc supplementation on intestinal permeability in experimental colitis. J Lab Clin Med 2002; 139: 311–5
   PubMed Web of Science ®Google Scholar
• Naito Y, Yohikawa T, Yagi N, Matsuyama K, Yoshida N, Seto K, et al. Effects of polaprezinc on lipid peroxidation, neutrophil accumulation, and TNF-alpha expression in rats with aspirin-induced gastric mucosal injury. Dig Dis Sci 2001; 46: 845–51
   PubMed Web of Science ®Google Scholar
• Shimada T, Watanabe N, Ohtsuka Y, Endoh M, Kojima K, Hiraichi H, et al. Polaprezinc down-regulates proinflammatory cytokine-induced nuclear factor-kappaB activation and interleukin-8 expression in gastric epithelial cells. J Pharmacol Exp Ther 1999; 291: 345–52
   PubMed Web of Science ®Google Scholar
• Marber MS, Mestril R, Chi SH, Sayen MR, Yellon DM, Dillmann WH. Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury. J Clin Invest 1995; 95: 1446–56
   PubMed Web of Science ®Google Scholar
• Pockley AG. Heat shock protein as regulators of the immune response. Lancet 2003; 362: 469–76
   PubMed Web of Science ®Google Scholar
• Ropeleski MJ, Tang J, Walsh-Reitz MM, Musch MW, Chang EB. Interleukin-11-induced heat shock protein 25 confers intestinal epithelial-specific cytoprotection from oxidant stress. Gastroenterology 2003; 124: 1358–68
   PubMed Web of Science ®Google Scholar
• Musch MW, Ciancio MJ, Sarge K, Chang EB. Induction of heat shock protein 70 protects intestinal epithelial IEC-18 cells from oxidant and thermal injury. Am J Physiol 1996; 270: C429–C36
   PubMed Web of Science ®Google Scholar
• Otani S, Otaka M, Jin M, Okuyama A, Itoh S, Iwabuchi A, et al. Effect of preinduction of heat shock proteins on acetic acid-induced colitis in rats. Dig Dis Sci 1997; 42: 833–46
   PubMed Web of Science ®Google Scholar
• Ren H, Musch MW, Kojima K, Boone D, Ma A, Chang EB. Short-chain fatty acids induce intestinal epithelial heat shock protein 25 expression in rats and IEC 18 cells. Gastroenterology 2001; 121: 631–9
   PubMed Web of Science ®Google Scholar
• Kojima K, Musch MW, Ren H, Boone DL, Hendrickson BA, Ma A, et al. Enteric flora and lymphocyte-derived cytokines determine expression of heat shock protein in mouse colonic epithelial cells. Gastroenterology 2003; 124: 1395–407
   PubMed Web of Science ®Google Scholar