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Original Article

Altered distribution of β-catenin and prognostic roles in colorectal carcinogenesis

, , , , , , , , & , PhD , MD show all
Pages 456-464 | Received 02 Jul 2007, Published online: 08 Jul 2009

References

  • Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996; 87: 159–70
  • Kolligs FT, Bommer G, Goke B. Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis. Digestion 2002; 66: 131–44
  • Giles RH, van Es JH, Clevers H. Caught up in a Wnt storm: Wnt signaling in cancer. Biochim Biophys Acta 2003; 1653: 1–24
  • BenZeev A, Geiger B. Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancer. Curr Opin Cell Biol 1998; 10: 629–39
  • Tetsu O, McCormick F. catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999; 398: 422–6
  • Wong SC, Lo SF, Cheung MT. Quantification of beta-catenin mRNA in colorectal cancer and adenoma patients. Clin Cancer Res 2004; 10: 1613–7
  • Wu WX, Zhang XH. Significance of β-catenin and Wnt pathway-related genes in colorectal adenoma. Chin J Cancer 2001; 20: 1005–7
  • Brembeck FH, Rosario M, Birchmeier W. Balancing cell adhesion and Wnt signaling, the key role of beta-catenin. Curr Opin Genet Dev 2006; 16: 51–9
  • van de Wetering, Barker N, Harkes IC, van der Heyden M, Dijk NJ, Hollestelle A, , et al. Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling. Cancer Res 2001;61:278–84.
  • Nelson WJ, Nusse R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 2004; 303: 1483–7
  • Vane JR, Botting RM. Mechanism of action of nonsteroidal anti-inflammatory drugs. Am J Med 1998; 104: 2–8S
  • Coussens LM, Werb Z. Inflammation and cancer. Nature 2002; 420: 860–7
  • Eberhart C, Coffey R, Radhika A, Giardiello F, Ferrenbach S, Dubois R. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 1004; 107: 1183–8
  • Fujino H, West KA, Regan JW. Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2. J Biol Chem 2002; 277: 2614–9
  • McEntee MF, Chiu CH, Whelan J. Relationship of beta-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min mice. Carcinogenesis 1999; 20: 635–40
  • Castellone MD, Teramoto H, Williams BO, Druey KM, Gutkind JS. Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-β-catenin signaling axis. Science 2005; 310: 1504–10
  • Shao J, Jung C, Liu C, Sheng H. Prostaglandin E2 Stimulates the beta-catenin/T cell factor-dependent transcription in colon cancer. J Biol Chem 2005; 280: 26565–72
  • Masunaga R, Kohno H, Dhar DK, Ohno S, Shibakita M, Kinugasa S, et al. Cyclooxygenase-2 expression correlates with tumor neovascularization and prognosis in human colorectal carcinoma patients. Clin Cancer Res 2000; 6: 4064–8
  • Lei SL, Zhao H, Feng DZ. Expression and significance of E-cadherin and CD44v6 in colorectal carcinoma. J Clin Exp Med (China) 2006; 5: 104–5
  • Maruyama K, Ochiai A, Akimoto S, Nakamura S, Baba S, Moriya Y, et al. Cytoplasmic beta-catenin accumulation as a predictor of the hematogenous metastasis in human colorectal cancer. Oncology 2000; 59: 302–9
  • Kawakami M, Kimura Y, Furuhata T, Zenbutsu H, Yanai Y, Mukaiya M, et al. beta-Catenin alteration in cancer of the ampulla of Vater. J Exp Clin Cancer Res 2002; 21: 23–7
  • Miller JR, Hocking AM, Brown JD, Moon RT. Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways. Oncogene 1999; 18: 7860–72
  • Valizadeh A, Karayiannakis AJ, El-Hariry I, Kmiot W, Pignatelli M. Expression of E-cadherin-associated molecules, α-,β- and γ-catenins and p120 in colorectal polyps. Am J Pathol 1997; 150: 1977–84
  • Wong S, Lo E, Lee K, Chan JK, Hsiao WL. Prognostic and diagnostic significance of β-catenin nuclear immunostaining in colorectal cancer. Clin Cancer Res 2004; 10: 1401–8
  • Iwamoto M, Hoffenberg EJ, Carethers JM, Doctolero R, Tajima A, Sugano K, et al. Nuclear accumulation of beta-catenin occurs commonly in the epithelial cells of juvenile polyps. Pediatr Res 2005; 57: 4–9
  • Han SA, Chun H, Park CM, Kang SJ, Kim SH, Sohn D, et al. Prognostic significance of beta-catenin in colorectal cancer with liver metastasis. Clin Oncol (R Coll Radiol) 2006; 18: 761–7
  • Wong SC, Lo ES, Chan AK, Lee KC, Hsiao WL. Nuclear beta catenin as a potential prognostic and diagnostic marker in patients with colorectal cancer from Hong Kong. Mol Pathol 2003; 56: 347–52
  • Miyamoto S, Endoh Y, Hasebe T, Ishii G, Kodama K, Goya M, et al. Nuclear beta-catenin accumulation as a prognostic factor in Dukes’ D human colorectal cancers. Oncol Rep 2004; 12: 245–51
  • Fuchs SY, Ougolkov AV, Spiegelman VS, Minamoto T. Oncogenic β-catenin signaling networks in colorectal cancer. Cell Cycle 2005; 4: 1522–39
  • Zhang M, Chen Z, Wang H. Immunohistochemical investigation of tumorigenic pathways in small intestinal adenocarcinoma: a comparison with colorectal adenocarcinoma. Mod Pathol 2006; 19: 573–80
  • Suh EK, Gumbiner BM. Translocation of beta-catenin into the nucleus independent of interactions with FG-rich nucleoporins. Exp Cell Res 2003; 290: 447–56
  • Henderson BR. Nuclear cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover. Nat Cell Biol 2001; 2: 653–60
  • Wang D, Wang H, Shi Q, Katkuri S, Walhi W, Desvergne B, et al. Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta. Cancer Cell 2004; 6: 285–95
  • Zhou J, Chen S, Zhang X, Zhou X, Zhu M, Feng B, et al. A novel APC gene germline mutation in a familial adenomatous polyposis pedigree. Chin J Med Genet 2006; 23: 388–91
  • Chen SP, Tsai ST, Jao SW, Huang YL, Chao YC, Chen YL, et al. Single nucleotide polymorphisms of the APC gene and colorectal cancer risk: a case-control study in Taiwan. BMC Cancer 2006; 6: 83
  • Yao H, Guo XL, Zhang SR, Shi QL. Expressions of axin and β-catenin in human colorectal cancer. Chin Remedies Clin 2006; 6: 805–8
  • Van Aken E, De Wever O, Correia da Rocha AS, Mareel M. Defective E-cadherin/catenin complexes in human cancer. Virchows Arch 2001; 439: 725–51
  • Roca F, Mauro LV, Morandi A, Bonadeo F, Vaccaro C, Quintana GO, et al. Prognostic value of E-cadherin, beta-catenin, MMPs (7 and 9), and TIMPs (1 and 2) in patients with colorectal carcinoma. J Surg Oncol 2006; 93: 151–60
  • Delektorskaya VV, Perevoshchikov AG, Golovkov DA, Kushlinskii NE. Expression of E-cadherin, beta-catenin, and CD-44v6 cell adhesion molecules in primary tumors and metastases of colorectal adenocarcinoma. Bull Exp Biol Med 2005; 139: 706–10

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