760
Views
41
CrossRef citations to date
0
Altmetric
Review Article

Perforated peptic ulcer: How to improve outcome?

, , &
Pages 15-22 | Received 22 Apr 2008, Published online: 08 Jul 2009

References

  • Tytgat GN. Treatment of peptic ulcer. Digestion 1998; 59: 446–52
  • Fineberg HV, Pearlman LA. Surgical treatment of peptic ulcer in the United States. Trends before and after the introduction of cimetidine. Lancet 1981; 131: 1305–7
  • Yuan Y, Padol IT, Hunt RH. Peptic ulcer disease today. Nat Clin Pract Gastroenterol Hepatol 2006; 3: 80–9
  • Svanes C. Trends in perforated peptic ulcer: incidence, etiology, treatment, and prognosis. World J Surg 2000; 24: 277–83
  • Svanes C, Salvesen H, Stangeland L, Svanes K, Soreide O. Perforated peptic ulcer over 56 years. Time trends in patients and disease characteristics. Gut 1993; 34: 1666–71
  • Ramakrishnan K, Salinas RC. Peptic ulcer disease. Am Fam Physician 2007; 76: 1005–12
  • Zittel TT, Jehle EC, Becker HD. Surgical management of peptic ulcer disease today – indication, technique and outcome. Langenbecks Arch Surg 2000; 385: 84–96
  • Vaira D, Menegatti M, Miglioli M. What is the role of Helicobacter pylori in complicated ulcer disease?. Gastroenterology 1997; 113(Suppl)S78–84
  • Behrman SW. Management of complicated peptic ulcer disease. Arch Surg 2005; 140: 201–8
  • Paimela H, Tuompo PK, Perakyl T, Saario I, Hockerstedt K, Kivilaakso E. Peptic ulcer surgery during the H2-receptor antagonist era: a population-based epidemiological study of ulcer surgery in Helsinki from 1972 to 1987. Br J Surg 1991; 78: 28–31
  • Blomgren LG. Perforated peptic ulcer: long-term results after simple closure in the elderly. World J Surg 1997; 21: 412–4
  • Collier DS, Pain JA. Non-steroidal anti-inflammatory drugs and peptic ulcer perforation. Gut 1985; 26: 359–63
  • Hermansson M, Staël von Holstein C, Zilling T. Peptic ulcer perforation before and after the introduction of H2-receptor blockers and proton pump inhibitors. Scand J Gastroenterol 1997; 32: 523–9
  • Cohen MM. Perforated peptic ulcer in the Vancouver area: a survey of 852 cases. Can Med Assoc J 1971; 104: 201–5
  • Hennessy E. Perforated peptic ulcer: mortality and morbidity in 603 cases. Aust N Z J Surg 1969; 38: 243–52
  • Jamieson RA. Acute perforated peptic ulcer; frequency and incidence in the West of Scotland. Br Med J 1955; 2: 222–7
  • MacKay C. Perforated peptic ulcer in the West of Scotland: a survey of 5,343 cases during 1954–63. Br Med J 1966; 1: 701–5
  • Svanes C, Lie RT, Kvale G, Svanes K, Soreide O. Incidence of perforated ulcer in western Norway, 1935–1990: cohort- or period-dependent time trends?. Am J Epidemiol 1995; 141: 836–44
  • Walt R, Katschinski B, Logan R, Ashley J, Langman M. Rising frequency of ulcer perforation in elderly people in the United Kingdom. Lancet 1986; 1: 489–92
  • Adamsen S, Bendix J, Kallehave F, Wille-Jørgensen P, Moesgaard F, Nakano A, et al. Perforated peptic ulcer. A national audit. Gut 2005; 54(Suppl VI)A46
  • Barut I, Tarhan OR, Cerci C, Karaguzel N, Akdeniz Y, Bulbul M. Prognostic factors of peptic ulcer perforation. Saudi Med J 2005; 26: 1255–9
  • Boey J, Choi SK, Poon A, Alagaratnam TT. Risk stratification in perforated duodenal ulcers. A prospective validation of predictive factors. Ann Surg 1987; 205: 22–6
  • Chou NH, Mok KT, Chang HT, Liu SI, Tsai CC, Wang BW, et al. Risk factors of mortality in perforated peptic ulcer. Eur J Surg 2000; 166: 149–53
  • Hermansson M, Staël von Holstein C, Zilling T. Surgical approach and prognostic factors after peptic ulcer perforation. Eur J Surg 1999; 165: 566–72
  • Irvin TT. Mortality and perforated peptic ulcer: a case for risk stratification in elderly patients. Br J Surg 1989; 76: 215–8
  • Kocer B, Surmeli S, Solak C, Unal B, Bozkurt B, Yildirim O, et al. Factors affecting mortality and morbidity in patients with peptic ulcer perforation. J Gastroenterol Hepatol 2007; 22: 565–70
  • Kujath P, Schwandner O, Bruch HP. Morbidity and mortality of perforated peptic gastroduodenal ulcer following emergency surgery. Langenbecks Arch Surg 2002; 387: 298–302
  • Lee FY, Leung KL, Lai BS, Ng SS, Dexter S, Lau WY. Predicting mortality and morbidity of patients operated on for perforated peptic ulcers. Arch Surg 2001; 136: 90–4
  • Mäkelä JT, Kiviniemi H, Ohtonen P, Laitinen SO. Factors that predict morbidity and mortality in patients with perforated peptic ulcers. Eur J Surg 2002; 168: 446–51
  • Noguiera C, Silva AS, Santos JN, Silva AG, Ferreira J, Matos E, et al. Perforated peptic ulcer: main factors of morbidity and mortality. World J Surg 2003; 27: 782–7
  • Sharma SS, Mamtani MR, Sharma MS, Kulkarni H. A prospective cohort study of postoperative complications in the management of perforated peptic ulcer. BMC Surg 2006; 6: 8
  • Testini M, Portincasa P, Piccinni G, Lissidini G, Pellegrini F, Greco L. Significant factors associated with fatal outcome in emergency open surgery for perforated peptic ulcer. World J Gastroenterol 2003; 9: 2338–40
  • Wakayama T, Ishizaki Y, Mitsusada M, Takahashi S, Wada T, Fukushima Y, et al. Risk factors influencing the short-term results of gastroduodenal perforation. Surg Today 1994; 24: 681–7
  • Moller MH, Shah K, Bendix J, Jensen AG, Zimmermann-Nielsen E, Adamsen S, et al. Risk factors in patients surgically treated for peptic ulcer perforation. Gut 2007; 56(Suppl III)A229–30
  • Kurata JH, Nogawa AN. Meta-analysis of risk factors for peptic ulcer. Nonsteroidal anti-inflammatory drugs, Helicobacter pylori, and smoking. J Clin Gastroenterol 1997; 24: 2–17
  • Matsukura N, Onda M, Tokunaga A, Kato S, Yoshiyuki T, Hasegawa H, et al. Role of Helicobacter pylori infection in perforation of peptic ulcer: an age- and gender-matched case-control study. J Clin Gastroenterol 1997; 25(Suppl 1)S235–9
  • Ng EK, Chung SC, Sung JJ, Lam YH, Lee DW, Lau JY, et al. High prevalence of Helicobacter pylori infection in duodenal ulcer perforations not caused by non-steroidal anti-inflammatory drugs. Br J Surg 1996; 83: 1779–81
  • Sebastian M, Chandran VP, Elashaal YI, Sim AJ. Helicobacter pylori infection in perforated peptic ulcer disease. Br J Surg 1995; 82: 360–2
  • Tokunaga Y, Hata K, Ryo J, Kitaoka A, Tokuka A, Ohsumi K. Density of Helicobacter pylori infection in patients with peptic ulcer perforation. J Am Coll Surg 1998; 186: 659–63
  • Svanes C, Ovrebo K, Soreide O. Ulcer bleeding and perforation: non-steroidal anti-inflammatory drugs or Helicobacter pylori. Scand J Gastroenterol Suppl 1996; 220: 128–31
  • Henry D, Dobson A, Turner C. Variability in the risk of major gastrointestinal complications from nonaspirin nonsteroidal anti-inflammatory drugs. Gastroenterology 1993; 105: 1078–88
  • Garcia Rodriguez LA, Jick H. Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs. Lancet 1994; 343: 769–72
  • Evans JM, McMahon AD, McGilchrist MM, White G, Murray FE, McDevitt DG, et al. Topical non-steroidal anti-inflammatory drugs and admission to hospital for upper gastrointestinal bleeding and perforation: a record linkage case-control study. Br Med J 1995; 311: 22–6
  • Parasher G, Eastwood GL. Smoking and peptic ulcer in the Helicobacter pylori era. Eur J Gastroenterol Hepatol 2000; 12: 843–53
  • Doll R, Peto R, Wheatley K, Gray R, Sutherland I. Mortality in relation to smoking: 40 years’ observations on male British doctors. Br Med J 1994; 309: 901–11
  • Reinbach DH, Cruickshank G, McColl KE. Acute perforated duodenal ulcer is not associated with Helicobacter pylori infection. Gut 1993; 34: 1344–7
  • Smedley F, Hickish T, Taube M, Yale C, Leach R, Wastell C. Perforated duodenal ulcer and cigarette smoking. J R Soc Med 1988; 81: 92–4
  • Svanes C, Soreide JA, Skarstein A, Fevang BT, Bakke P, Vollset SE, et al. Smoking and ulcer perforation. Gut 1997; 41: 177–80
  • Svanes C, Lie RT, Svanes K, Lie SA, Soreide O. Adverse effects of delayed treatment for perforated peptic ulcer. Ann Surg 1994; 220: 168–75
  • Copeland GP. The POSSUM system of surgical audit. Arch Surg 2002; 137: 15–9
  • Egberts JH, Summa B, Schulz U, Schafmayer C, Hinz S, Tepel J. Impact of preoperative physiological risk profile on postoperative morbidity and mortality after emergency operation of complicated peptic ulcer disease. World J Surg 2007; 31: 1449–57
  • Koç M, Yoldas O, Kilic YA, Gocmen E, Ertan T, Dizen H, et al. Comparison and validation of scoring systems in a cohort of patients treated for perforated peptic ulcer. Langenbecks Arch Surg 2007; 392: 581–5
  • Chiarugi M, Buccianti P, Goletti O, Decanini L, Sidoti F, Cavina E. Prognostic risk factors in patients operated on for perforated peptic ulcer. A retrospective analysis of critical factors of mortality and morbidity in a series of 40 patients who underwent simple closure surgery. Ann Ital Chir 1996; 67: 609–13
  • Martinez JP, Mattu A. Abdominal pain in the elderly. Emerg Med Clin North Am 2006; 24: 371–88, vii
  • Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992; 101: 1644–55
  • Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 2008; 36: 296–327
  • Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, et al. Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Crit Care Med 2004; 32: 858–73
  • Gabay C, Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med 1999; 340: 448–54
  • Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001; 345: 1368–77
  • Svanes C, Salvesen H, Espehaug B, Soreide O, Svanes K. A multifactorial analysis of factors related to lethality after treatment of perforated gastroduodenal ulcer. 1935–1985. Ann Surg 1989; 209: 418–23
  • Ford AC, Delaney BC, Forman D, Moayyedi P. Eradication therapy for peptic ulcer disease in Helicobacter pylori positive patients. Cochrane Database Syst Rev 2006;(2):CD003840.
  • Ng EK, Lam YH, Sung JJ, Yung MY, To KF, Chan AC, et al. Eradication of Helicobacter pylori prevents recurrence of ulcer after simple closure of duodenal ulcer perforation: randomized controlled trial. Ann Surg 2000; 231: 153–8
  • Graham RR. The treatment of perforated duodenal ulcer. Surg Gynecol Obstet 1937; 64: 235–8
  • Donovan AJ, Berne TV, Donovan JA. Perforated duodenal ulcer: an alternative therapeutic plan. Arch Surg 1998; 133: 1166–71
  • Bulut OB, Rasmussen C, Fischer A. Acute surgical treatment of complicated peptic ulcers with special reference to the elderly. World J Surg 1996; 20: 574–7
  • Lau WY, Leow CK. History of perforated duodenal and gastric ulcers. World J Surg 1997; 21: 890–6
  • Tokunaga Y, Hata K, Ryo J, Kitaoka A, Tokuka A, Ohsumi K. Density of Helicobacter pylori infection in patients with peptic ulcer perforation. J Am Coll Surg 1998; 186: 659–63
  • Nathanson LK, Easter DW, Cuschieri A. Laparoscopic repair/peritoneal toilet of perforated duodenal ulcer. Surg Endosc 1990; 4: 232–3
  • Mouret P, Francois Y, Vignal J, Barth X, Lombard-Platet R. Laparoscopic treatment of perforated peptic ulcer. Br J Surg 1990; 77: 1006
  • Sanabria AE, Morales CH, Villegas MI. Laparoscopic repair for perforated peptic ulcer disease. Cochrane Database Syst Rev 2005;(4):CD004778.
  • Marshall C, Ramaswamy P, Bergin FG, Rosenberg IL, Leaper DJ. Evaluation of a protocol for the non-operative management of perforated peptic ulcer. Br J Surg 1999; 86: 131–4
  • Crofts TJ, Park KG, Steele RJ, Chung SS, Li AK. A randomized trial of nonoperative treatment for perforated peptic ulcer. N Engl J Med 1989; 320: 970–3
  • Bucher P, Oulhaci W, Morel P, Ris F, Huber O. Results of conservative treatment for perforated gastroduodenal ulcers in patients not eligible for surgical repair. Swiss Med Wkly 2007;137:337–40.
  • Ersumo T, Meskel Y, Kotisso B. Perforated peptic ulcer in Tikur Anbessa Hospital: a review of 74 cases. Ethiop Med J 2005; 43: 9–13
  • Rivers EP, Coba V, Whitmill M. Early goal-directed therapy in severe sepsis and septic shock: a contemporary review of the literature. Curr Opin Anaesthesiol 2008; 21: 128–40
  • Belda FJ, Aguilera L, Garcia de la AJ, Alberti J, Vicente R, Ferrandiz L, et al. Supplemental perioperative oxygen and the risk of surgical wound infection: a randomized controlled trial. JAMA 2005; 294: 2035–42
  • Cuthbertson BH, Boroujerdi M, McKie L, Aucott L, Prescott G. Can physiological variables and early warning scoring systems allow early recognition of the deteriorating surgical patient?. Crit Care Med 2007; 35: 402–9
  • Giuliano KK. Physiological monitoring for critically ill patients: testing a predictive model for the early detection of sepsis. Am J Crit Care 2007; 16: 122–30
  • Giuliano KK. Continuous physiologic monitoring and the identification of sepsis: what is the evidence supporting current clinical practice?. AACN Adv Crit Care 2006; 17: 215–23
  • Villet S, Chiolero RL, Bollmann MD, Revelly JP, Cayeux RNM, Delarue J, et al. Negative impact of hypocaloric feeding and energy balance on clinical outcome in ICU patients. Clin Nutr 2005; 24: 502–9
  • Tonnessen T, Carlsen E. Perforated ulcer. Tidsskr Nor Laegeforen 2001; 121: 790–2
  • Christensen S, Riis A, Norgaard M, Thomsen RW, Tonnesen EM, Larsson A, et al. Perforated peptic ulcer: use of pre-admission oral glucocorticoids and 30-day mortality. Aliment Pharmacol Ther 2006; 23: 45–52

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.