60
Views
9
CrossRef citations to date
0
Altmetric
Esophagus

A more than 10-year prospective, follow-up study of esophageal and pharyngeal acid exposure, symptoms and laryngeal findings in healthy, asymptomatic volunteers

, MD, , &
Pages 23-31 | Received 01 Jun 2008, Published online: 08 Jul 2009

References

  • Revicki DA, Wood M, Maton PN, Sorensen S. The impact of gastroesophageal reflux disease on health-related quality of life. Am J Med 1998; 104: 252–8
  • Dent J, El-Serag HB, Wallander MA, Johansson S. Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut 2005; 54: 710–7
  • El-Serag HB. Time trends of gastroesophageal reflux disease: a systematic review. Clin Gastroenterol Hepatol 2007; 5: 17–26
  • Fullard M, Kang JY, Neild P, Poullis A, Maxwell JD. Systematic review: does gastro-oesophageal reflux disease progress?. Aliment Pharmacol Ther 2006; 24: 33–45
  • Labenz J, Nocon M, Lind T, Leodolter A, Jaspersen D, Meyer-Sabellek W, et al. Prospective follow-up data from the ProGERD study suggest that GERD is not a categorical disease. Am J Gastroenterol 2006; 101: 2457–62
  • Pace F, Bollani S, Molteni P, Bianchi Porro G. Natural history of gastro-oesophageal reflux disease without oesophagitis (NERD) – a reappraisal 10 years on. Dig Liver Dis 2004; 36: 111–5
  • Fass R, Ofman JJ. Gastroesophageal reflux disease – should we adopt a new conceptual framework?. Am J Gastroenterol 2002; 97: 1901–9
  • Vakil N. The frontiers of reflux disease. Dig Dis Sci 2006; 51: 1887–95
  • Ylitalo R, Lindestad P, Hertegard S. Pharyngeal and laryngeal symptoms and signs related to extraesophageal reflux in patients with heartburn in gastroenterology practice: a prospective study. Clin Otolaryngol 2005; 30: 347–52
  • Hicks DM, Ours TM, Abelson TI, Vaezi MF, Richter JE. The prevalence of hypopharynx findings associated with gastroesophageal reflux in normal volunteers. J Voice 2002; 16: 564–79
  • Milstein CF, Charbel S, Hicks DM, Abelson TI, Richter JE, Vaezi MF. Prevalence of laryngeal irritation signs associated with reflux in asymptomatic volunteers: impact of endoscopic technique (rigid vs. flexible laryngoscope). Laryngoscope 2005; 115: 2256–61
  • Qadeer MA, Phillips CO, Lopez AR, Steward DL, Noordzij JP, Wo JM, et al. Proton pump inhibitor therapy for suspected GERD-related chronic laryngitis: a meta-analysis of randomized controlled trials. Am J Gastroenterol 2006; 101: 2646–54
  • Bove M, Ruth M, Cange L, Mansson I. 24-H pharyngeal pH monitoring in healthy volunteers: a normative study. Scand J Gastroenterol 2000; 35: 234–41
  • Andersson O, Ylitalo R, Finizia C, Bove M, Magnus R. Pharyngeal reflux episodes at pH 5 in healthy volunteers. Scand J Gastroenterol 2006; 41: 138–43
  • Ruth M, Mansson I, Sandberg N. The prevalence of symptoms suggestive of esophageal disorders. Scand J Gastroenterol 1991; 26: 73–81
  • Ruth M, Finizia C, Lundell L. Occurrence and future history of oesophageal symptoms in an urban Swedish population: results of a questionnaire-based, ten-year follow-up study. Scand J Gastroenterol 2005; 40: 629–35
  • Nilsson M, Johnsen R, Ye W, Hveem K, Lagergren J. Obesity and estrogen as risk factors for gastroesophageal reflux symptoms. JAMA 2003; 290: 66–72
  • Grande L, Lacima G, Ros E, Pera M, Ascaso C, Visa J, et al. Deterioration of esophageal motility with age: a manometric study of 79 healthy subjects. Am J Gastroenterol 1999; 94: 1795–801
  • Loof L, Gotell P, Elfberg B. The incidence of reflux oesophagitis. A study of endoscopy reports from a defined catchment area in Sweden. Scand J Gastroenterol 1993; 28: 113–8
  • Fass R. Erosive esophagitis and nonerosive reflux disease (NERD): comparison of epidemiologic, physiologic, and therapeutic characteristics. J Clin Gastroenterol 2007; 41: 131–7
  • Castell DO, Mainie I, Tutuian R. Non-acid gastroesophageal reflux: documenting its relationship to symptoms using multichannel intraluminal impedance (MII). Trans Am Clin Climatol Assoc 2005;116:321–33; discussion 333–4.
  • Martinez SD, Malagon IB, Garewal HS, Cui H, Fass R. Non-erosive reflux disease (NERD) – acid reflux and symptom patterns. Aliment Pharmacol Ther 2003; 17: 537–45
  • Ronkainen J, Aro P, Storskrubb T, Johansson SE, Lind T, Bolling-Sternevald E, et al. High prevalence of gastroesophageal reflux symptoms and esophagitis with or without symptoms in the general adult Swedish population: a Kalixanda study report. Scand J Gastroenterol 2005; 40: 275–85
  • Byrne PJ, Power C, Lawlor P, Ravi N, Reynolds JV. Laryngopharyngeal reflux in patients with symptoms of gastroesophageal reflux disease. Dis Esophagus 2006; 19: 377–81
  • Ylitalo R, Ramel S, Hammarlund B, Lindgren E. Prevalence of extraesophageal reflux in patients with symptoms of gastroesophageal reflux. Otolaryngol Head Neck Surg 2004; 131: 29–33
  • Vaezi MF. Laryngitis and gastroesophageal reflux disease: increasing prevalence or poor diagnostic tests?. Am J Gastroenterol 2004; 99: 786–8
  • Joniau S, Bradshaw A, Esterman A, Carney AS. Reflux and laryngitis: a systematic review. Otolaryngol Head Neck Surg 2007; 136: 686–92
  • Noordzij JP, Khidr A, Desper E, Meek RB, Reibel JF, Levine PA. Correlation of pH probe-measured laryngopharyngeal reflux with symptoms and signs of reflux laryngitis. Laryngoscope 2002; 112: 2192–5
  • Tauber S, Gross M, Issing WJ. Association of laryngopharyngeal symptoms with gastroesophageal reflux disease. Laryngoscope 2002; 112: 879–86
  • Talley NJ, Weaver AL, Zinsmeister AR, Melton LJ, III. Onset and disappearance of gastrointestinal symptoms and functional gastrointestinal disorders. Am J Epidemiol 1992; 136: 165–77
  • Vaezi MF. Sensitivity and specificity of reflux-attributed laryngeal lesions: experimental and clinical evidence. Am J Med 2003; 115(Suppl 3A)97S–104
  • Ylitalo R, Lindestad PA, Ramel S. Symptoms, laryngeal findings, and 24-hour pH monitoring in patients with suspected gastroesophago-pharyngeal reflux. Laryngoscope 2001; 111: 1735–41
  • Branski RC, Bhattacharyya N, Shapiro J. The reliability of the assessment of endoscopic laryngeal findings associated with laryngopharyngeal reflux disease. Laryngoscope 2002; 112: 1019–24
  • Franchi A, Brogelli B, Massi D, Santucci M, De Campora E, Gallo O. Dilation of intercellular spaces is associated with laryngo-pharyngeal reflux: an ultrastructural morphometric analysis of laryngeal epithelium. Eur Arch Otorhinolaryngol 2007; 264: 907–11

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.