Curcumin reverses attenuated carbachol-induced contraction of the colon in a rat model of colitis

References

• Podolsky DK. Inflammatory bowel disease. N Engl J Med 2002; 347: 417–29
   PubMed Web of Science ®Google Scholar
• Odashima M, Otaka M, Jin M, Horikawa Y, Matsuhashi T, Ohba R, et al. Successful treatment of refractory duodenal Crohn's disease with infliximab. Dig Dis Sci 2007; 52: 31–2
   PubMed Web of Science ®Google Scholar
• Cuzzocrea S, Chatterjee PK, Mazzon E, Dugo L, Serraino I, Britti D, et al. Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation. Br J Pharmacol 2002; 135: 496–510
   PubMed Web of Science ®Google Scholar
• Fröde-Saleh TS, Calixto JB. Synergistic antiinflammatory effect of NF kappaB inhibitors and steroidal or non-steroidal antiinflammatory drugs in the pleural inflammation induced by carrageenan in mice. Inflamm Res 2000; 49: 330–7
   PubMed Web of Science ®Google Scholar
• Sanchez-Hidalgo M, Martin AR, Villegas I, Alarcon de la Lastra C. Rosiglitazone, a PPARγ ligand, modulates signal transduction pathways during the development of acute TNBS-induced colitis in rats. Eur J Pharmacol 2007; 562: 247–58
   PubMed Web of Science ®Google Scholar
• Sugimoto K, Hanai H, Tozawa K, Aoshi T, Uchijima M, Nagata T, Koide Y. Curcumin prevents and ameliorates trinitrobenzene sulfonic acid-induced colitis in mice. Gastroenterology 2002; 123: 1912–22
   PubMed Web of Science ®Google Scholar
• Ukil A, Maity S, Karmakar S, Datta N, Vedasiromoni JR, Das PK. Curcumin, the major component of food flavour turmeric, reduces mucosal injury in trinitrobenzene sulphonic acid-induced colitis. Br J Pharmacol 2003; 139: 209–18
   PubMed Web of Science ®Google Scholar
• Jian YT, Mai GF, Wang JD, Zhang YL, Luo RC, Fang YX. Preventive and therapeutic effects of NF-kappaB inhibitor curcumin in rat colitis induced by trinitrobenzene sulfonic acid. World J. Gastroenterol 2005; 11: 1747–52
   Google Scholar
• Salh B, Assi K, Templeman V, Parhar K, Owen D, Gomez-Munoz A, et al. Curcumin attenuates DNB-induced murine colitis. Am J. Physiol 2003; 285: G235–43
   Google Scholar
• Venkataranganna MV, Rafiq M, Gopumadhavan S, Peer G, Babu UV, Mitra SK. NCB-02 (standardized Curcumin preparation) protects dinitrochlorobenzene- induced colitis through down-regulation of NFkappa-B and iNOS. World J Gastroenterol 2007; 13: 1103–7
   PubMed Web of Science ®Google Scholar
• Deguchi Y, Andoh A, Inatomi O, Yagi Y, Bamba S, Araki Y, et al. Curcumin prevents the development of dextran sulfate sodium (DSS)-induced experimental colitis. Dig Dis Sci 2007; 52: 2993–8
   PubMed Web of Science ®Google Scholar
• Fox-Robichaud AE, Collins SM. Altered calcium-handling properties of jejunal smooth muscle from the nematode-infected rat. Gastroenterology 1986; 91: 1462–9
   PubMed Web of Science ®Google Scholar
• Grossi L, McHugh K, Collins SM. On the specificity of altered muscle function in experimental colitis in rats. Gastroenterology 1993; 104: 1049–56
   PubMed Web of Science ®Google Scholar
• Khan I, Oriowo MA, Anim JT. Amelioration of experimental colitis by Na-H exchanger-1 inhibitor amiloride is associated with reversal of IL-1β and ERK mitogen activated protein kinase. Scand J Gastroenterol 2005; 40: 578–85
   PubMed Web of Science ®Google Scholar
• Wells RW, Blennerhassett MG. Persistent and selective effects of inflammation on smooth muscle cell contractility in rat colitis. Pflugers Arch 2004; 448: 515–24
   PubMed Web of Science ®Google Scholar
• Martinsson T, Ljung T, Rubio C, Hellström PM. Beneficial effects of ropivacaine in rat experimental colitis. J Pharmacol Exp Ther 1999; 291: 642–7
   PubMed Web of Science ®Google Scholar
• Khan I, Oriowo MA. Mechanism underlying the reversal of contractility dysfunction in experimental colitis by cyclooxygenase-2 inhibition. Inflammopharmacology 2006; 14: 28–35
   PubMedGoogle Scholar
• Kinoshita K, Sato K, Hori M, Ozaki H, Karaki H. Decrease in activity of smooth muscle L-type Ca2 +  channels and its reversal by NF-κB inhibitors in Crohn's colitis model. Am J Physiol 2003; 285: G483–93
   Google Scholar
• Bou-Fersen AM, Anim JT, Khan I. Experimental colitis is associated with ultrastructural changes in inflamed and uninflamed regions of the gastrointestinal tract. Med Princ Pract 2008; 17: 190–6
   PubMed Web of Science ®Google Scholar
• Snape WJ, Jr, Kao HW. Role of inflammatory mediators in colonic smooth muscle function in ulcerative colitis. Dig Dis Sci 1988; 33 Suppl 3: 65S–70S
   Google Scholar
• Myers BM, Martin JS, Dempsey DT, Parkman HP, Thomas RM, Ryan JP. Acute experimental colitis decreases colonic circular smooth muscle contractility in rats. Am J Physiol 1997; 273: G928–36
   Google Scholar
• Hosseini JM, Goldhill JM, Bossone C, Pineiro-Carrero V, Shea-Donohue T. Progressive alterations in circular smooth muscle contractility in TNBS-induced colitis in rats. Neurogastroenterol Motil 1999; 11: 347–56
   PubMed Web of Science ®Google Scholar
• Shi XZ, Sarna SK. Impairment of Ca2 +  mobilization in circular muscle cells of the inflamed colon. Am J Physiol 2000; 278: G234–42
   Google Scholar
• Natale L, Piepoli AL, De Salvia MA, De Salvatore G, Mitolo CI, Marzullo A, et al. Interleukins-1β and 6 induce functional alteration of rat colonic motility: an in vitro study. Eur J Clin Invest 2003; 33: 704–12
   PubMed Web of Science ®Google Scholar
• Al-Jarallah A, Khan I, Oriowo MA. Role of Ca2 + -sensitization in attenuated carbachol-induced contraction of,the colon in a rat model of colitis. Eur J Pharmacol 2008; 579: 365–73
   PubMed Web of Science ®Google Scholar
• Sato K, Ohkura S, Kitahara Y, Ohama T, Hori M, Sato M, et al. Involvement of CPI-17 down-regulation in the dysmotility of the colon from dextran sodium sulfate-induced experimental colitis in a mouse model. Neurogastroenterol Motil 2007; 19: 504–14
   PubMed Web of Science ®Google Scholar
• Aube AC, Blottiere HM, Scarpignato C. Inhibition of acetylcholine induced intestinal motility by interleukin 1beta in the rat. Gut 1996; 39: 470–4
   PubMed Web of Science ®Google Scholar
• Vrees MD, Pricalo VE, Potenti FM, Cao W. Abnormal motility in patients with ulcerative colitis Arch Surg 2002; 137: 439–46
   Google Scholar
• Ohama T, Hori M, Sato K, Ozaki H, Karaki H. Chronic treatment with interleukin-1β attenuates contractions by decreasing the activities of CPI-17 and MYPT-1 in intestinal smooth muscle. J Biol Chem 2003; 278: 48794–804
   PubMed Web of Science ®Google Scholar
• Cao W, Fiocchi C, Pricolo VE. Production of IL-1β, hydrogen peroxide and nitric oxide by colonic mucosa decreases sigmoid smooth muscle contractility in ulcerative colitis. Am J Physiol 2005; 289: C1408–16
   Google Scholar
• Tomita R, Tanjoh K, Fzuisaki S, Ikeda T, Koshinaga T. The role of interleukin-1 beta (IL-1beta) in the normal human colon in vitro. Hepatogastroenterology 2005; 52: 464–8
   PubMedGoogle Scholar
• Hu W, Mahavadi S, Li F, Murthy KS. Upregulation of RGS4 and downregulation of CPI-17 mediate inhibition of colonic muscle contraction by interleukin-1beta. Am J Physiol 2007; 293: C1991–2000
   PubMed Web of Science ®Google Scholar
• Lodato RF, Khan AR, Zembowicz MJ, Weisbrodt NW, Pressley TA, Li Y, et al. Roles of IL-1 and TNF in the decreased ileal muscle contractility induced by lipopolysaccharide. Am J Physiol 1999; 276: G1356–62
   Google Scholar
• Khan I, Al-Awadi FM. Colonic muscle enhances the production of interleukin-1β messenger RNA in experimental colitis. Gut 1997; 40: 307–12
   PubMed Web of Science ®Google Scholar
• Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 1998; 115: 182–205
   PubMed Web of Science ®Google Scholar
• Ishiguro Y. Mucosal proinflammatory cytokine production correlates with endoscopic activity of ulcerative colitis. J Gastroenterol 1999; 34: 66–74
   PubMed Web of Science ®Google Scholar
• Bachmeier B, Nerlich AG, Iancu CM, Cilli M, Schleicher E, Vené R, et al. The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice. Cell Physiol Biochem 2007; 19: 137–52
   PubMed Web of Science ®Google Scholar
• Weber WM, Hunsaker LA, Roybal CN, Bobrovnikova-Marjon EV, Abcouwer SF, Royer RE, et al. Activation of NFkappaB is inhibited by curcumin and related enones. Bioorg Med Chem 2006; 14: 2450–61
   PubMed Web of Science ®Google Scholar
• Yeh CH, Chen TP, Wu YC, Lin YM, Jing Lin P. Inhibition of NFkappaB activation with curcumin attenuates plasma inflammatory cytokines surge and cardiomyocytic apoptosis following cardiac ischemia/reperfusion. J Surg Res 2005; 125: 109–16
   PubMed Web of Science ®Google Scholar