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Inflammatory Bowel Disease

Intravenous iron sucrose is superior to oral iron sulphate for correcting anaemia and restoring iron stores in IBD patients: A randomized, controlled, evaluator-blind, multicentre study

, PhD , MD, , , , , , , , & show all
Pages 838-845 | Received 19 Dec 2008, Published online: 21 Jul 2009

References

  • Cronin C, Shanahan F. Anemia in patients with chronic inflammatory bowel disease. Am J Gastroenterol 2001; 96: 2296–8
  • Gasché C, Lomer MC, Cavill I, Weiss G. Iron, anaemia, and inflammatory bowel diseases. Gut 2004; 53: 1190–7
  • Guagnozzi D, Severi C, Ialongo P, Viscido A, Patrizi F, Testino G, et al. Ferritin as a simple indicator of iron deficiency in anemic IBD patients. Inflam Bowel Dis 2006; 12: 150–1
  • Gasché C, Dejaco C, Waldhoer T, Tillinger W, Rainisch W, Fueger GF, et al. Intravenous iron and erythropoietin for anemia associated with Crohn disease. Ann Int Med 1997; 126: 782–7
  • Wells CW, Lewis S, Barton JR, Corbett S. Effects of changes in hemoglobin level on quality of life and cognitive function in inflammatory bowel disease patients. Inflam Bowel Dis 2006; 12: 123–30
  • Gasché C, Dejaco C, Reinisch W, Tillinger W, Waldhoer T, Fueger GF, et al. Sequential treatment of anemia in ulcerative colitis with intravenous iron and erythropoietin. Digestion 1999; 60: 262–7
  • Gasché C, Waldhoer T, Feichtenschlager T, Male C, Mayer A, Mittermaier C, et al. Prediction of response to iron sucrose in inflammatory bowel disease-associated anemia. Am J Gastroenterol 2001; 96: 2382–7
  • Bodemar G, Kechagias S, Almer S, Danielson BG. Treatment of anaemia in inflammatory bowel disease with iron sucrose. Scand J Gastroenterol 2004; 39: 454–8
  • Bailie GR, Clark JA, Lane CE, Lane PL. Hypersensitivity reactions and deaths associated with intravenous iron preparations. Nephrol Dial Transplant 2005; 20: 1443–9
  • Van Wyck DB, Cavallo G, Spinowitz BS, Adhikarla R, Gagnon S, Charytan C, et al. Safety and efficacy of iron sucrose in patients sensitive to iron dextran: North American Clinical Trial. Am J Kidney Dis 2000; 36: 88–97
  • Schröder O, Mickisch O, Seidler U, de Weerth A, Dignass AU, Herfarth H, et al. Intravenous iron sucrose versus oral iron supplementation for the treatment of iron deficiency anemia in patients with inflammatory bowel disease: a randomized, controlled, open-label, multicenter study. Am J Gastroenterol 2005; 100: 2503–9
  • Ganzoni AM. Intravenous iron-dextran: therapeutic and experimental possibilities. Schweiz Med Wochenschrift 1970; 100: 301–3
  • Skjelbakken T, Langbakk B, Dahl IMS, Löchen M-L. Haemoglobin and anaemia in a gender perspective: The Tromsö Study. Eur J Haematol 2005; 74: 381–8
  • Harvey RF, Bradshaw JM. A simple index of Crohn's disease activity. Lancet 1980; 1: 514
  • Walmsley RS, Ayres RC, Pounder RE, Allan RN. A simple clinical colitis activity index. Gut 1998; 43: 29–32
  • White SJ, Freedmann LS. Allocation of patients to treatment groups in a controlled clinical study. Br J Cancer 1978; 37: 849–57
  • Goddard AF, McIntyre AS, Scott BB. Guidelines for the management of iron deficiency anaemia. British Society of Gastroenterology. Gut 2000;46 Suppl 3-4:IV1–5. Erratum in: Gut 2000; 47: 872
  • Gasché C, Berstad A, Befrits R, Beglinger C, Dignass A, Erichsen K, et al. Guidelines on the diagnosis and management of iron deficiency and anemia in inflammatory bowel disease. Inflamm Bowel Dis 2007; 13: 1545–53
  • Erichsen K, Ulvik RJ, Nysaeter G, Johansen J, Ostborg J, Berstad A, et al. Oral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease. Scand J Gastroenterol 2005; 40: 1058–65
  • Kulnigg S, Gasché C. Systematic review: managing anaemia in Crohn's disease. Aliment Pharmacol Ther 2006; 24: 1507–23
  • Yee J, Besarab A. Iron sucrose: the oldest iron therapy becomes new. Am J Kidney Dis 2002; 40: 1111–21
  • Besarab A, Frinak S, Yee J. An indistinct balance: the safety and efficacy of parenteral iron therapy. J Am Soc Nephrol 1999; 10: 2029–43
  • Chertow GM, Mason PD, Vaage-Nilsen O, Ahlmén J. Update on adverse drug events associated with parenteral iron. Nephrol Dial Transplant 2006; 21: 378–82
  • Danielson BG, Beshara S. Pharmacokinetics and utilization of iron sucrose. Am J Kidney Dis 2003; 42: 1104
  • Ganz T, Nemeth E. Iron imports. IV. Hepcidin and regulation of body iron metabolism. Am J Physiol GI 2005; 290: 199–203
  • Semrin G, Fishman DS, Bousvaros A, Zholudev A, Saunders AC, Correia CE, et al. Impaired intestinal iron absorption in Crohn's disease correlates with disease activity and markers of inflammation. Inflam Bowel Dis 2006; 12: 1101–6
  • Gasché C, Reinisch W, Lochs H, Parsaei B, Bakos S, Wyatt J, et al. Anemia in Crohn's disease. Importance of inadequate erythropoietin production and iron deficiency. Digestive Dis Sci 1994; 39: 1930–4

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