Advanced search
Publication Cover
Scandinavian Journal of Gastroenterology Volume 9, 1974 - Issue 2
Submit an article Journal homepage
5
Views
42
CrossRef citations to date
0
Altmetric
Articles

The Role of the Colon in the Metabolism of Salicylazosulphapyridine

K. M. DasGastro-intestinal Unit, Western General Hospital, and the University of Edinburgh, Western General Hospital, Edinburgh, Scotland
,
M. A. EastwoodGastro-intestinal Unit, Western General Hospital, and the University of Edinburgh, Western General Hospital, Edinburgh, Scotland
,
J. P. A. McManusGastro-intestinal Unit, Western General Hospital, and the University of Edinburgh, Western General Hospital, Edinburgh, Scotland
&
W. SircusGastro-intestinal Unit, Western General Hospital, and the University of Edinburgh, Western General Hospital, Edinburgh, Scotland
Pages 137-141 | Received 14 Mar 1973, Accepted 25 Jul 1973, Published online: 16 Oct 2020

REFERENCES

  • Baron, J. H., Connell, A. M., Lennard-Jones, J. E. & Jones, F. A. Sulphasalazine and salicylazosulphadimidine in ulcerative colitis. Lumet 1962, 1, 1094.
  • Bottiger, L. E. & Mollerberg, H. Metabolic studies on Azulfidine, Azudimidine and one Analogue. Acta med. scand. 1959, 165, 241.
  • Das, K. M., Eastwood, M. A., McManus, J. P. A. & Sircus, W. The metabolism of salicylazosulphapyridine in ulcerative colitis. Gut 1973, 14, 631–642.
  • Dick, A. P., Grayson, M. J., Carpenter, R. G. & Petrie, A. Controlled trial of Sulphasalazin in the treatment of ulcerative colitis. Gut 1964. 5, 437.
  • Dyer, N. H. Medical management of Crohn’s Disease. Clinics in Gastroenterology 1972, 1, No. 2, 459.
  • Finegold, S. M., Sutter, V. L., Boylem J. D. et al. The normal flora of ileostomy and transverse colostomy effluents. J. Infect. Dis. 1970, 122, 376.
  • Fouts, J. R., Kamm, J. J. & Brodie, B. B. Enzymatic reduction of prontosil and other azo dyes. J. Pharmacol, exp. Ther. 1957, 120, 291.
  • Goldstein, F. & Murdock, M. G. Clinical and radiological improvement of regional enteritis and enterocolitis after treatment with salicylazosulphapyridin, Amer. J. dig. Dis. 1972, 6, 421.
  • Gorbach, S. L., Nahas, L., Weinstein, L., et al. Studies of intestinal microflora. IV. Microflora of ileostomy effluent: unique microbial ecology. Gastroenterology 1967, 53, 874.
  • Hannson, K.-A. & Sandberg, M. Determination of sulphapyridin and its metabolites in biological materials after administration of salicylazosulphapyridin. Acta pharm. suec. 1972, in press.
  • Hannson, K.-A. Determination of free and acetylated 5-amino salicylic acid in serum and urine after administration of salicylazosulphapyridine. Acta pharm. suec. 1972, in press.
  • Misiewicz, J. J., Lennard-Jones, J. F., Connell, A. M., Baron, J. H. & Jones, F. A. Controlled trial of sulphasalazine in maintenance for ulcerative colitis. Lancet 1965, 1, 185.
  • Sandberg, J. & Hansson, K.-A. Determination of salicylazosulphapyridinc in biological materials, Acta pharm. suec. 1972, in press.
  • Schroder, H. & Campbell, D. E. S. Absorption metabolism and excretion of salicylazosulfapyridine. Clin. Pharmacol, Ther. 1972, 13, 539.
  • Soleim, H. A. & Scheline, R R. Metabolism of xenobiotics by strains of intestinal bacteria. Acta pharmacol. (Khh.) 1972, 31, 471–480.
  • Svartz, N. Salazopyrin, a new sulfanilamide preparation. Acta med, scand. 1942, 110, 577.
  • Svartz, N., Kallner, S. & Helander, S. Sonderdela salazopyrin snabbt I organismen. Journal Nordisk Med. 1945, 25. 211 212.
  • Walker, R. The metabolism of azo compounds: A review of the literature. Cosmet. Toxicol. 1970, 8, 659–767.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.