Reduced neural baroreflex sensitivity is related to enhanced endothelial function in patients with end-stage liver disease

References

• Veglio F, Melchio R, Calva S, et al. Noninvasive assessment of spontaneous baroreflex sensitivity in patients with liver cirrhosis. Liver. 1998;18:420–426.
   PubMedGoogle Scholar
• Barron HV, Alam I, Lesh MD, et al. Autonomic nervous system tone measured by baroreflex sensitivity is depressed in patients with end-stage liver disease. Am J Gastroenterol. 1999;94:986–989.
   PubMed Web of Science ®Google Scholar
• Møller S, Iversen JS, Henriksen JH, et al. Reduced baroreflex sensitivity in alcoholic cirrhosis: relations to hemodynamics and humoral systems. Am J Physiol Heart Circ Physiol. 2007;292:H2966–H2972.
   PubMed Web of Science ®Google Scholar
• Pérez-Peña J, Rincón D, Bañares R, et al. Autonomic neuropathy is associated with hemodynamic instability during human liver transplantation. Transplant Proc. 2003;35:1866–1868.
   PubMed Web of Science ®Google Scholar
• Hendrickse MT, Thuluvath PJ, Triger DR. Natural history of autonomic neuropathy in chronic liver disease. Lancet. 1992;339:1462–1464.
   PubMed Web of Science ®Google Scholar
• Fleckenstein JF, Frank S, Thuluvath PJ. Presence of autonomic neuropathy is a poor prognostic indicator in patients with advanced liver disease. Hepatology. 1996;23:471–475.
   PubMed Web of Science ®Google Scholar
• Hunt BE, Fahy L, Farquhar WB, et al. Quantification of mechanical and neural components of vagal baroreflex in humans. Hypertension. 2001;37:1362–1368.
   PubMed Web of Science ®Google Scholar
• Paton JF, Deuchars J, Ahmad Z, et al. Adenoviral vector demonstrates that angiotensin II-induced depression of the cardiac baroreflex is mediated by endothelial nitric oxide synthase in the nucleus tractus solitarii of the rat. J Physiol. 2001;531:445–458.
   PubMed Web of Science ®Google Scholar
• Smith SA, Mitchell JH, Li J. Independent modification of baroreceptor and exercise pressor reflex function by nitric oxide in nucleus tractus solitarius. Am J Physiol Heart Circ Physiol. 2005;288:H2068–H2076.
   PubMed Web of Science ®Google Scholar
• Talman WT, Dragon DN. Transmission of arterial baroreflex signals depends on neuronal nitric oxide synthase. Hypertension. 2004;43:820–824.
   PubMed Web of Science ®Google Scholar
• Spieker LE, Corti R, Binggeli C, et al. Baroreceptor dysfunction induced by nitric oxide synthase inhibition in humans. J Am Coll Cardiol. 2000;36:213–218.
   PubMed Web of Science ®Google Scholar
• Albillos A, Rossi I, Cacho G, et al. Enhanced endothelium-dependent vasodilation in patients with cirrhosis. Am J Physiol. 1995;268:G459–G464.
   PubMedGoogle Scholar
• Cazzaniga M, Salerno F, Visentin S, et al. Increased flow-mediated vasodilation in cirrhotic patients with ascites: relationship with renal resistive index. Liver Int. 2008;28:1396–1401.
   PubMed Web of Science ®Google Scholar
• Parati G, Di Rienzo M, Mancia G. How to measure baroreflex sensitivity: from the cardiovascular laboratory to daily life. J Hypertens. 2000;18:7–19.
   PubMed Web of Science ®Google Scholar
• La Rovere MT, Pinna GD, Raczak G. Baroreflex sensitivity: measurement and clinical implications. Ann Noninvasive Electrocardiol. 2008;13:191–207.
   PubMed Web of Science ®Google Scholar
• Davies LC, Francis D, Jurak P, et al. Reproducibility of methods for assessing baroreflex sensitivity in normal controls and in patients with chronic heart failure. Clin Sci. 1999;97:515–522.
   PubMed Web of Science ®Google Scholar
• Bonyhay I, Jokkel G, Kollai M. Relation between baroreflex sensitivity and carotid artery elasticity in healthy humans. Am J Physiol. 1996;271:H1139–H1144.
   PubMed Web of Science ®Google Scholar
• Reneman RS, van Merode T, Brands PJ, et al. Inhomogeneities in arterial wall properties under normal and pathological conditions. J Hypertens. 1992;10:S35–S39.
   Web of Science ®Google Scholar
• Vastagh I, Horváth T, Garamvölgyi Z, et al. Preserved structural and functional characteristics of common carotid artery in properly treated normoglycemic women with gestational diabetes mellitus. Acta Physiol Hung. 2011;98:294–304.
   PubMedGoogle Scholar
• Van Bortel LM, Duprez D, Starmans-Kool MJ, et al. Clinical applications of arterial stiffness, Task Force III: recommendations for user procedures. Hypertens. 2002;15:445–452.
   Web of Science ®Google Scholar
• Lenard Z, Studinger P, Mersich B, et al. Maturation of cardiovagal autonomic function from childhood to young adult age. Circulation. 2004;110:2307–2312.
   PubMed Web of Science ®Google Scholar
• Thijssen DH, Black MA, Pyke KE, et al. Assessment of flow-mediated dilation in humans: a methodological and physiological guideline. Am J Physiol Heart Circ Physiol. 2011;300:H2–12.
   PubMed Web of Science ®Google Scholar
• Ghiadoni L, Faita F, Salvetti M, et al. Assessment of flow-mediated dilation reproducibility: a nationwide multicenter study. J Hypertens. 2012;30:1399–1405.
   PubMed Web of Science ®Google Scholar
• Hendrickse MT, Triger DR. Peripheral and cardiovascular autonomic impairment in chronic liver disease: prevalence and relation to hepatic function. J Hepatol. 1992;16:177–183.
   PubMed Web of Science ®Google Scholar
• Jain J, Singh R, Banait S, et al. Magnitude of peripheral neuropathy in cirrhosis of liver patients from central rural India. Ann Indian Acad Neurol. 2014;17:409–415.
   PubMed Web of Science ®Google Scholar
• Pintér A, Horváth T, Tóth A, et al. Impaired baroreflex function is related to reduced carotid artery elasticity in patients with tetralogy of Fallot. Auton Neurosci. 2014;183:94–99.
   PubMed Web of Science ®Google Scholar
• Studinger P, Lénárd Z, Mersich B, et al. Determinants of baroreflex function in juvenile end-stage renal disease. Kidney Int. 2006;69:2236–2242.
   PubMed Web of Science ®Google Scholar
• Ruiz J, Monbaron D, Parati G, et al. Diabetic neuropathy is a more important determinant of baroreflex sensitivity than carotid elasticity in type 2 diabetes. Hypertension. 2005;46:162–167.
   PubMed Web of Science ®Google Scholar
• Szili-Török T, Kálmán J, Paprika D, et al. Depressed baroreflex sensitivity in patients with Alzheimer's and Parkinson's disease. Neurobiol Aging. 2001;22:435–438.
   PubMed Web of Science ®Google Scholar
• Monforte R, Estruch R, Valls-Solé J, et al. Autonomic and peripheral neuropathies in patients with chronic alcoholism: a dose-related toxic effect of alcohol. Arch Neurol. 1995;52:45–51.
   PubMedGoogle Scholar
• Mellion M, Gilchrist JM, de la Monte S. Alcohol-related peripheral neuropathy: nutritional, toxic, or both? Muscle Nerve. 2011;43:309–316.
   PubMed Web of Science ®Google Scholar
• Martinez AR, Nunes MB, Nucci A, et al. Sensory neuronopathy and autoimmune diseases. Autoimmune Dis. 2012;2012:Article ID 873587, 6 pages.
   PubMedGoogle Scholar
• Stojanovich L, Milovanovich B, de Luka SR, et al. Cardiovascular autonomic dysfunction in systemic lupus, rheumatoid arthritis, primary Sjögren syndrome and other autoimmune diseases. Lupus. 2007;16:181–185.
   PubMed Web of Science ®Google Scholar
• Jeffrey GP, Muller DP, Burroughs AK, et al. Vitamin E deficiency and its clinical significance in adults with primary biliary cirrhosis and other forms of chronic liver disease. J Hepatol. 1987;4:307–317.
   PubMed Web of Science ®Google Scholar
• Muller DP. Vitamin E and neurological function. Mol Nutr Food Res. 2010;54:710–718.
   PubMed Web of Science ®Google Scholar
• Tanyel MC, Mancano LD. Neurologic findings in vitamin E deficiency. Am Fam Physician. 1997;55:197–201.
   PubMed Web of Science ®Google Scholar
• Vallance P, Moncada S. Hyperdynamic circulation in cirrhosis: a role for nitric oxide? Lancet. 1991;337:776–778.
   PubMed Web of Science ®Google Scholar
• Niederberger M, Martin PY, Ginès P, et al. Normalization of nitric oxide production corrects arterial vasodilation and hyperdynamic circulation in cirrhotic rats. Gastroenterology. 1995;109:1624–1630.
   PubMed Web of Science ®Google Scholar
• de Franchis R, Faculty BV. Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension. J Hepatol. 2010;53:762–768.
   PubMed Web of Science ®Google Scholar
• Kroeger RJ, Groszmann RJ. The effect of the combination of nitroglycerin and propranolol on splanchnic and systemic hemodynamics in a portal hypertensive rat model. Hepatology. 1985;5:425–430.
   PubMed Web of Science ®Google Scholar
• Reiberger T, Ferlitsch A, Payer BA, et al. Non-selective betablocker therapy decreases intestinal permeability and serum levels of LBP and IL-6 in patients with cirrhosis. J Hepatol. 2013;58:911–921.
   PubMed Web of Science ®Google Scholar
• Horvath T, Pinter A, Kollai M. Carotid artery stiffness is not related to endothelial function in young healthy subjects. Auton Neurosci. 2012;166:85–88.
   PubMed Web of Science ®Google Scholar
• Waki H, Kasparov S, Wong LF, et al. Chronic inhibition of endothelial nitric oxide synthase activity in nucleus tractus solitarii enhances baroreceptor reflex in conscious rats. J Physiol (Lond). 2003;546:233–242.
   Google Scholar
• Pontieri V, Venezuela MK, Scavone C, et al. Role of endogenous nitric oxide in the nucleus tratus solitarii on baroreflex control of heart rate in spontaneously hypertensive rats. J Hypertens. 1998;16:1993–1999.
   PubMedGoogle Scholar
• Yee KM, Struthers AD. Endogenous angiotensin II and baroreceptor dysfunction: a comparative study of losartan and enalapril in man. Br J Clin Pharmacol. 1998;46:583–588.
   PubMed Web of Science ®Google Scholar
• Monahan KD, Leuenberger UA, Ray CA. Aldosterone impairs baroreflex sensitivity in healthy adults. Am J Physiol Heart Circ Physiol. 2007;292:H190–H197.
   PubMed Web of Science ®Google Scholar
• Parlow J, Viale JP, Annat G, et al. Spontaneous cardiac baroreflex in humans: comparison with drug-induced responses. Hypertension. 1995;25:1058–1068.
   PubMed Web of Science ®Google Scholar
• Anderson TJ, Uehata A, Gerhard MD, et al. Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol. 1995;26:1235–1241.
   PubMed Web of Science ®Google Scholar
• Debbabi H, Bonnin P, Ducluzeau PH, et al. Noninvasive assessment of endothelial function in the skin microcirculation. Am J Hypertens. 2010;23:541–546.
   PubMed Web of Science ®Google Scholar