2,262
Views
6
CrossRef citations to date
0
Altmetric
Original Article

Intestinal metaplasia at the gastroesophageal junction is associated with gastroesophageal reflux but not with Helicobacter pylori infection

, , &
Pages 1179-1185 | Received 15 Mar 2018, Accepted 17 Sep 2018, Published online: 05 Dec 2018

References

  • Lagergren J, Bergström R, Lindgren A, et al. Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. N Engl J Med. 1999;340:825–831.
  • Buttar NS, Wang KK, Sebo TJ, et al. Extent of high-grade dysplasia in Barrett's esophagus correlates with risk of adenocarcinoma. Gastroenterol. 2001;120:1630–1639.
  • Devesa SS, Blot WJ, Fraumeni JF. Jr. Changing patterns in the incidence of esophageal and gastric carcinoma in the United States. Cancer. 1998;83:2049–2053.
  • Correa P. Human gastric carcinogenesis: a multistep and multifactorial process-first American cancer society award lecture on cancer epidemiology and prevention. Cancer Res. 1992;52:6735–6740.
  • Spechler SJ, Zeroogian JM, Antonioli DA, et al. Prevalence of metaplasia at the gastro-oesophageal junction. Lancet. 1994;344:1533–1536.
  • Sharma P, Weston AP, Morales T, et al. Relative risk of dysplasia for patients with intestinal metaplasia in the distal oesophagus and in the gastric cardia. Gut. 2000;46:9–13.
  • Öberg S, Peters JH, DeMeester TR, et al. Inflammation and specialized intestinal metaplasia of cardiac mucosa is a manifestation of gastroesophageal reflux disease. Ann Surg. 1997;226:522–530.
  • Voutilainen M, Sipponen P, Mecklin JP, et al. Gastroesophageal reflux disease: prevalence, clinical, endoscopic and histopathological findings in 1,128 consecutive patients referred for endoscopy due to dyspeptic and reflux symptoms. Digestion. 2000;61:6–13.
  • Oksanen A, Sipponen P, Karttunen R, et al. Inflammation and intestinal metaplasia at the squamocolumnar junction in young patients with or without Helicobacter pylori infection. Gut. 2003;52:194–198.
  • Carton E, Caldwell MT, McDonald G, et al. Specialized intestinal metaplasia in patients with gastro-oesophageal reflux disease. Br J Surg. 2000;87:116–121.
  • Goldblum JR, Vicari JJ, Falk GW, et al. Inflammation and intestinal metaplasia of the gastric cardia: the role of gastroesophageal reflux and H. pylori infection. Gastroenterol. 1998;114:633–639.
  • Hirota WK, Loughney TM, Lazas DJ, et al. Specialized intestinal metaplasia, dysplasia, and cancer of the esophagus and esophagogastric junction: prevalence and clinical data. Gastroenterol. 1999;116:277–285.
  • Morales TG, Sampliner RE, Bhattacharyya A. Intestinal metaplasia of the gastric cardia. Am J Gastroenterol. 1997;92:414–418.
  • Morini S, Zullo A, Hassan C, et al. Gastric cardia inflammation: role of Helicobacter pylori infection and symptoms of gastroesophageal reflux disease. Am J Gastroenterol. 2001;96:2337–2340.
  • Pascarenco OD, Boeriu A, Mocan S, et al. Barrett's esophagus and intestinal metaplasia of gastric cardia: prevalence, clinical, endoscopic and histological features. J Gastrointestin Liver Dis. 2014;23:19–25.
  • Pieramico O, Zanetti MV. Relationship between intestinal metaplasia of the gastro-oesophageal junction, Helicobacter pylori infection and gastro-oesophageal reflux disease: a prospective study. Dig Liver Dis. 2000;32:567–572.
  • Hackelsberger A, Gunther T, Schultze V, et al. Intestinal metaplasia at the gastro-oesophageal junction: Helicobacter pylori gastritis or gastro-oesophageal reflux disease? Gut. 1998;43:17–21.
  • Wolf C, Seldenrijk CA, Timmer R, et al. Epidemiological, clinical, and histological characteristics of intestinal metaplasia at the oesophagogastric junction compared to short segments of columnar-lined oesophagus. Eur J Gastroenterol Hepatol. 2001;13:113–120.
  • Wenner J, Johnsson F, Johansson J, et al. Acid reflux immediately above the squamocolumnar junction and in the distal esophagus: simultaneous pH monitoring using the wireless capsule pH system. Am J Gastroenterol. 2006;101:1734–1741.
  • Wenner J, Johnsson F, Johansson J, et al. Wireless oesophageal pH monitoring: feasibility, safety and normal values in healthy subjects. Scand J Gastroenterol. 2005;40:768–774.
  • Wenner J, Johansson J, Johnsson F, et al. Optimal thresholds and discriminatory power of 48-h wireless esophageal pH monitoring in the diagnosisof GERD. Am J Gastroenterol. 2007;102:1862–1869.
  • Wallner B, Sylvan A, Stenling R, et al. The esophageal Z-line appearance correlates to the prevalence of intestinal metaplasia. Scand J Gastroenterol. 2000;35:17–22.
  • Odze RD. Unraveling the mystery of the gastroesophageal junction: a pathologist's perspective. Am J Gastroenterol. 2005;100:1853–1867.
  • Wenner J, Hall M, Höglund P, et al. Wireless pH recording immediately above the squamocolumnar junction improves the diagnostic performance of esophageal pH studies. Am J Gastroenterol. 2008;103:2977–2985.
  • Guerrero Garcia Hall M, Wenner J, Öberg S. The normal squamocolumnar junction is circumferentially even and minimal irregularities are manifestations of gastroesophageal acid reflux. Scand J Gastroenterol. 2017;52:270–275.
  • Aksglaede K, Funch-Jensen P, Thommesen P. Intra-esophageal pH probe movement during eating and talking. A videoradiographic study. Acta Radiol. 2003;44:131–135.
  • Kahrilas PJ, Wu S, Lin S, et al. Attenuation of esophageal shortening during peristalsis with hiatus hernia. Gastroenterol. 1995;109:1818–1825.
  • Pandolfino JE, Richter JE, Ours T, et al. Ambulatory esophageal pH monitoring using a wireless system. Am J Gastroenterol. 2003;98:740–749.
  • Law S, Lam KY, Chu KM, et al. Specialized intestinal metaplasia and carditis at the gastroesophageal junction in Chinese patients undergoing endoscopy. Am J Gastroenterol. 2002;97:1924–1929.
  • Sharma P, McElhinney C, Topalovski M, et al. Detection of cardia intestinal metaplasia: do the biopsy number and location matter? Am J Gastroenterol. 2004;99:2424–2428.
  • Couvelard A, Cauvin JM, Goldfain D, et al. Cytokeratin immunoreactivity of intestinal metaplasia at normal oesophagogastric junction indicates its aetiology. Gut. 2001;49:761–766.
  • Felley C, Bouzourene H, VanMelle MB, et al. Age, smoking and overweight contribute to the development of intestinal metaplasia of the cardia. Wjg. 2012;18:2076–2083.
  • Guelrud M, Herrera I, Essenfeld H, et al. Intestinal metaplasia of the gastric cardia: a prospective study with enhanced magnification endoscopy. Am J Gastroenterol. 2002;97:584–589.
  • Malfertheiner P, Megraud F, O'Morain CA, et al. Management of Helicobacter pylori infection-the Maastricht V/Florence Consensus Report. Gut. 2017;66:6–30.
  • Roberts SE, Morrison-Rees S, Samuel DG, et al. Review article: the prevalence of Helicobacter pylori and the incidence of gastric cancer across Europe. Aliment Pharmacol Ther. 2016;43:334–345.
  • Agreus L, Hellström PM, Talley NJ, et al. Towards a healthy stomach? Helicobacter pylori prevalence has dramatically decreased over 23 years in adults in a Swedish community. United Eur Gastroenterol J. 2016;4:686–696.
  • Öberg S, Johansson J, Wenner J, et al. Metaplastic columnar mucosa in the cervical esophagus after esophagectomy. Ann Surg. 2002;235:338–345.
  • Öberg S, DeMeester TR, Peters JH, et al. The extent of Barrett's esophagus depends on the status of the lower esophageal sphincter and the degree of esophageal acid exposure. J Thoracic Cardiovasc Surg. 1999;117:572–580.
  • Boyce HW. Endoscopic definitions of esophagogastric junction regional anatomy. Gastrointest Endosc. 2000;51:586–592.
  • DeNardi FG, Riddell RH. The normal esophagus. Am J Surg Pathol. 1991;15:296–309.
  • Huang Q. Definition of the esophagogastric junction: a critical mini review. Arch Pathol Lab Med. 2011;135:384–389.
  • Morales CP, Spechler SJ. Intestinal metaplasia at the gastroesophageal junction: Barrett's, bacteria, and biomarkers. Am J Gastroenterol. 2003;98:759–762.
  • Soucy G, Onstad L, Vaughan TL, et al. Histologic features associated with columnar-lined esophagus in distal esophageal and gastroesophageal junction (GEJ) biopsies from GERD patients: a community-based population study. Am J Surg Pathol. 2016;40:827–835.
  • Spechler SJ. Intestinal metaplasia at the gastroesophageal junction. Gastroenterol. 2004;126:567–575.
  • Anaparthy R, Gaddam S, Kanakadandi V, et al. Association between length of Barrett's esophagus and risk of high-grade dysplasia or adenocarcinoma in patients without dysplasia. Clin Gastroenterol Hepatol. 2013;11:1430–1436.