Treatment of locally advanced pancreatic cancer with irreversible electroporation – a Danish single center study of safety and feasibility

References

• Ryan DP, Hong TS, Bardeesy N. Pancreatic adenocarcinoma. N Engl J Med. 2014;371:1039–1049.
   PubMed Web of Science ®Google Scholar
• Konstantinidis IT, Warshaw AL, Allen JN, et al. Pancreatic ductal adenocarcinoma: is there a survival difference for R1 resections versus locally advanced unresectable tumors? What is a “true” R0 resection? Ann Surg. 2013;257:731–735.
   PubMed Web of Science ®Google Scholar
• Stender MT, Larsen AC, Sall M, et al. d-Dimer predicts prognosis and non-resectability in patients with pancreatic cancer. Blood Coagul Fibrinol. 2016;27:597–601.
   PubMed Web of Science ®Google Scholar
• Bernards N, Haj Mohammad N, Creemers G-J, et al. Ten weeks to live: a population-based study on treatment and survival of patients with metastatic pancreatic cancer in the south of the Netherlands. Acta Oncol. 2015;54:403-410.
   Web of Science ®Google Scholar
• Ducreux M, Cuhna AS, Caramella C, et al. Cancer of the pancreas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2015;26:v56–v68.
   PubMed Web of Science ®Google Scholar
• Tempero MA, Malafa MP, Behrman SW, et al. Pancreatic adenocarcinoma, Version 2.2014 featured updates to the NCCN guidelines. JNCCN J Natl Compr Cancer Netw. 2014;12:1671–1680.
   PubMed Web of Science ®Google Scholar
• Al-Sakere B, André F, Bernat C, et al. Tumor ablation with irreversible electroporation. PLoS One. 2007;2:1–8.
   Web of Science ®Google Scholar
• Bower M, Sherwood L, Li Y, et al. Irreversible electroporation of the pancreas: definitive local therapy without systemic effects. J Surg Oncol. 2011;104:22–28.
   PubMed Web of Science ®Google Scholar
• Charpentier KP, Wolf F, Noble L, et al. Irreversible electroporation of the pancreas in swine: a pilot study. HPB. 2010;12:348–351.
   PubMed Web of Science ®Google Scholar
• Pillai K, Akhter J, Chua TC, et al. Heat sink effect on tumor ablation characteristics as observed in monopolar radiofrequency, bipolar radiofrequency, and microwave, using ex vivo calf liver model. Medicine (United States). 2015;94:e580.
   Google Scholar
• Zorbas G, Samaras T. A study of the sink effect by blood vessels in radiofrequency ablation. Comput Biol Med. 2015;57:182–186.
   PubMed Web of Science ®Google Scholar
• Davalos RV, Mir LM, Rubinsky B. Tissue ablation with irreversible electroporation. Ann Biomed Eng. 2005;33:223–231.
   PubMed Web of Science ®Google Scholar
• Charpentier KP, Wolf F, Noble L, et al. Irreversible electroporation of the liver and liver hilum in swine. HPB. 2011;13:168–173.
   PubMed Web of Science ®Google Scholar
• Scheffer HJ, Vroomen LGPH, de Jong MC, et al. Ablation of locally advanced pancreatic cancer with percutaneous irreversible electroporation: results of the phase I/II PANFIRE study. Radiology. 2017;282:585–597.
   PubMed Web of Science ®Google Scholar
• Dansk Pancreas Cancer Gruppe (DPCG). Nationale Kliniske Retningslinier – pancreas cancer [Internet]. [cited 2018 Oct 10]. Available from: http://dpcg.gicancer.dk/Default.aspx?pID=22
   Google Scholar
• Martin RCG. Irreversible electroporation of locally advanced pancreatic head adenocarcinoma. J Gastrointest Surg. 2013;17:1850–1856.
   PubMed Web of Science ®Google Scholar
• Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205–213.
   PubMed Web of Science ®Google Scholar
• Clavien PA, Barkun J, De Oliveira ML, et al. The Clavien–Dindo classification of surgical complications: five-year experience. Ann Surg. 2009;250:187–196.
   PubMed Web of Science ®Google Scholar
• Ansari D, Kristoffersson S, Andersson R, et al. The role of irreversible electroporation (IRE) for locally advanced pancreatic cancer: a systematic review of safety and efficacy. Scand J Gastroenterol. 2017;52:1165–1171.
   PubMed Web of Science ®Google Scholar
• Wu Y, Tang Z, Fang H, et al. High operative risk of cool-tip radiofrequency ablation for unresectable pancreatic head cancer. J Surg Oncol. 2006;94:392–395.
   PubMed Web of Science ®Google Scholar
• Varshney S, Sewkani A, Sharma S, et al. Radiofrequency ablation of unresectable pancreatic carcinoma: feasibility, efficacy and safety. J Pancreas. 2006;7:74-78.
   PubMedGoogle Scholar
• Girelli R, Frigerio I, Salvia R, et al. Feasibility and safety of radiofrequency ablation for locally advanced pancreatic cancer. Br J Surg. 2010;97:220–225.
   PubMed Web of Science ®Google Scholar
• D’Onofrio M, Barbi E, Girelli R, et al. Radiofrequency ablation of locally advanced pancreatic adenocarcinoma: an overview. World J Gastroenterol. 2010;16:3478–3483.
   PubMed Web of Science ®Google Scholar
• CADTH. Irreversible electroporation for tumors of the pancreas or liver: a review of clinical and cost-effectiveness [Internet]. Irreversible electroporation tumors pancreas or liver A Rev. Clin. Cost-effectiveness. Canadian Agency for Drugs and Technologies in Health; 2016. [cited 2019 Jan 10]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27030853.
   Google Scholar
• Månsson C, Brahmstaedt R, Nilsson A, et al. Percutaneous irreversible electroporation for treatment of locally advanced pancreatic cancer following chemotherapy or radiochemotherapy. Eur J Surg Oncol. 2016;42:1401–1406.
   PubMed Web of Science ®Google Scholar
• Leen E, Picard J, Stebbing J, et al. Percutaneous irreversible electroporation with systemic treatment for locally advanced pancreatic adenocarcinoma. J Gastrointest Oncol. 2018;9:275–281.
   PubMed Web of Science ®Google Scholar
• Narayanan G, Hosein PJ, Beulaygue IC, et al. Percutaneous image-guided irreversible electroporation for the treatment of unresectable, locally advanced pancreatic adenocarcinoma. J Vasc Interv Radiol. 2017;28:342–348.
   PubMed Web of Science ®Google Scholar
• Kluger MD, Epelboym I, Schrope BA, et al. Single-institution experience with irreversible electroporation for T4 pancreatic cancer: first 50 patients. Ann Surg Oncol. 2016;23:1736–1743.
   PubMed Web of Science ®Google Scholar
• Martin RCG, Kwon D, Chalikonda S, et al. Treatment of 200 locally advanced (stage III) pancreatic adenocarcinoma patients with irreversible electroporation. Ann Surg. 2015;262:486–494.
   PubMed Web of Science ®Google Scholar
• Martin RCG, Durham AN, Besselink MG, et al. Irreversible electroporation in locally advanced pancreatic cancer: a call for standardization of energy delivery. J Surg Oncol. 2016;114:865–871.
   PubMed Web of Science ®Google Scholar
• Dunki-Jacobs EM, Philips P, Martin RCG. Evaluation of resistance as a measure of successful tumor ablation during irreversible electroporation of the pancreas. J Am Coll Surg. 2014;218:179–187.
   PubMed Web of Science ®Google Scholar
• Martin RCG. Irreversible electroporation of locally advanced pancreatic neck/body adenocarcinoma. J Gastrointest Oncol. 2015;6:329–335.
   PubMed Web of Science ®Google Scholar