429
Views
19
CrossRef citations to date
0
Altmetric
Original Article

Clinical results and microbiota changes after faecal microbiota transplantation for chronic pouchitis: a pilot study

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon show all
Pages 421-429 | Received 30 Jan 2020, Accepted 23 Mar 2020, Published online: 14 Apr 2020

References

  • Hata K, Ishihara S, Nozawa H, et al. Pouchitis after ileal pouch-anal anastomosis in ulcerative colitis: diagnosis, management, risk factors, and incidence. Dig Endosc. 2017;29(1):26–34.
  • Fazio V, Kiran R, Remzi F, et al. Ileal pouch anal anastomosis: analysis of outcome and quality of life in 3707 patients. Ann Surg. 2013;257(4):679–685.
  • Sandborn W. Pouchitis following ileal pouch-anal anastomosis: definition, pathogenesis, and treatment. Gastroenterology 1994;107(6):1856–1860.
  • Shen B. Acute and chronic pouchitis–pathogenesis, diagnosis and treatment. Nat Rev Gastroenterol Hepatol. 2012;9(6):323–333.
  • Segal JP, Oke S, Hold GL, et al. Systematic review: ileoanal pouch microbiota in health and disease. Aliment Pharmacol Ther. 2018;47(4):466–477.
  • Marchesi J, Adams D, Fava F, et al. The gut microbiota and host health: a new clinical frontier. Gut. 2016;65(2):330–339.
  • Tannock GW, Lawley B, Munro K, et al. Comprehensive analysis of the bacterial content of stool from patients with chronic pouchitis, normal pouches, or familial adenomatous polyposis pouches. Inflamm Bowel Dis. 2012;18(5):925–934.
  • Shen B, Achkar J, Lashner B, et al. Endoscopic and histologic evaluation together with symptom assessment are required to diagnose pouchitis. Gastroenterology. 2001;121(2):261–267.
  • Isaacs K, Sandler R, Abreu M, et al. Rifaximin for the treatment of active pouchitis: a randomized, double-blind, placebo-controlled pilot study. Inflamm Bowel Dis. 2007;13(10):1250–1255.
  • Nguyen N, Zhang B, Holubar SD, et al. Treatment and prevention of pouchitis after ileal pouch-anal anastomosis for chronic ulcerative colitis. Cochrane Database Syst Rev. 2019;(5):CD001176.
  • Herfarth H, Long M, Isaacs K. Use of biologics in pouchitis: a systematic review. Gastroenterology. 2015;49(8):647–654.
  • Mimura T, Rizzello F, Helwig U, et al. Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis. Gut. 2004;53(1):108–114.
  • Segal J, Ding N, Worley G, et al. Systematic review with meta-analysis: the management of chronic refractory pouchitis with an evidence-based treatment algorithm. Aliment Pharmacol Ther. 2017;45(5):581–592.
  • Hirata A, Uchino M, Bando T, et al. Long-term outcomes and sex differences after restorative proctocolectomy in pediatric patients with ulcerative colitis. J Pediatr Surg. 2016;51(3):454–460.
  • Quraishi M, Widlak M, Bhala N, et al. Systematic review with meta-analysis: the efficacy of faecal microbiota transplantation for the treatment of recurrent and refractory Clostridium difficile infection. Aliment Pharmacol Ther. 2017;46(5):479–493.
  • Weingarden A, González A, Vázquez-Baeza Y, et al. Dynamic changes in short- and long-term bacterial composition following fecal microbiota transplantation for recurrent Clostridium difficile infection. Microbiome. 2015;3(1):1–8.
  • Shahinas D, Silverman M, Sittler T, et al. Toward an understanding of changes in diversity associated with fecal microbiome transplantation based on 16S rRNA gene deep sequencing. MBio. 2012;3(5):1–10.
  • Costello SP, Hughes PA, Waters O, et al. Effect of fecal microbiota transplantation on 8-week remission in patients with ulcerative colitis. JAMA. 2019;321(2):156.
  • Paramsothy S, Kamm MA, Kaakoush NO, et al. Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial. Lancet. 2017;389(10075):1218–1228.
  • Moayyedi P, Surette MG, Kim PT, et al. Fecal microbiota transplantation induces remission in patients with active ulcerative colitis in a randomized controlled trial. Gastroenterology. 2015;149(1):102–109.e6.
  • Rossen NG, Fuentes S, Van Der Spek MJ, et al. Findings from a randomized controlled trial of fecal transplantation for patients with ulcerative colitis. Gastroenterology. 2015;149(1):110–118.e4.
  • Fang S, Kraft CS, Dhere T, et al. Successful treatment of chronic pouchitis utilizing fecal microbiota transplantation (FMT): a case report. Int J Colorectal Dis. 2016;31(5):1093–1094.
  • Landy J, Walker AW, Li JV, et al. Variable alterations of the microbiota, without metabolic or immunological change, following faecal microbiota transplantation in patients with chronic pouchitis. Sci Rep. 2015;5(1):12955.
  • Schmid M, Frick JS, Malek N, et al. Successful treatment of pouchitis with Vedolizumab, but not fecal microbiota transfer (FMT), after proctocolectomy in ulcerative colitis. Int J Colorectal Dis. 2017;32(4):597–598.
  • Stallmach A, Lange K, Buening J, et al. Fecal microbiota transfer in patients with chronic antibiotic-refractory pouchitis. Am J Gastroenterol. 2016;111(3):441–443.
  • Nishida A, Imaeda H, Inatomi O, et al. The efficacy of fecal microbiota transplantation for patients with chronic pouchitis: a case series. Clin Case Rep. 2019;7(4):782–788.
  • Herfarth H, Barnes EL, Long MD, et al. Combined endoscopic and oral fecal microbiota transplantation in patients with antibiotic-dependent pouchitis: low clinical efficacy due to low donor microbial engraftment. Inflamm Intest Dis. 2019;4(1):1–6.
  • Selvig D, Piceno Y, Terdiman J, et al. Fecal microbiota transplantation in pouchitis: clinical, endoscopic, histologic, and microbiota results from a pilot study. Dig Dis Sci. 2020;65(4):1099–1106.
  • Sandborn W, Tremaine W, Batts K, et al. Pouchitis after ileal pouch-anal anas-tomosis: a pouchitis disease activity index. Mayo Clin Proc. 1994;69(5):409–415.
  • Shen B, Lashner B. Diagnosis and treatment of pouchitis. Gastroenterol Hepatol. 2008;4(5):355–361.
  • Cammarota G, Ianiro G, Tilg H, et al. European consensus conference on faecal microbiota transplantation in clinical practice. Gut. 2017;66(4):569–580.
  • Cammarota G, Ianiro G, Kelly CR, et al. International consensus conference on stool banking for faecal microbiota transplantation in clinical practice. Gut. 2019;68(12):2111–2121.
  • Edgar R. Search and clustering orders of magnitude faster than BLAST. Bioinformatics. 2010;26(19):2460–2461.
  • Edgar R. SINTAX: a simple non-Bayesian taxonomy classifier for 16S and ITS sequences. bioRxiv. 2016. DOI:10.1101/074161
  • Andersen K, Kirkegaard R, Karst S, et al. ampvis2: An R package to analyse and visualise 16S rRNA amplicon data. bioRxiv. 2018. DOI:10.1101/299537
  • Oksanen J, Blanchet F, Kindt R, et al. vegan: Community Ecology Package. R package version 1.17-2. 2011 [cited 2020 Mar 30]. Available from: https://kityna.ga/548893pdf.pdf
  • Dowle M, Srinivasan A, Gorecki J, et al. data.table: Extension of “data.frame.” 2019 [cited 2020 Mar 30]. Available from: https://cran.r-project.org/web/packages/data.table
  • Wickham H. ggplot2: Elegant Graphics for Data Analysis. ggplot2. 2016 [cited 2020 Mar 30]. Available from: https://ggplot2-book.org/
  • Wickham H, Henry L. tidyr: Tidy Messy Data. 2019 [cited 2020 Mar 30]. Available from: https://cran.r-project.org/web/packages/tidyr/inde
  • Sorensen T. A method of establishing groups of equal amplitude in plant sociology based on similarity of species content. DET K DANSKE Vidensk Selsk Biol Skr. 1948;5(4):34.
  • Love MI, Huber W, Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 2014;15(12):550.
  • Ni J, Wu G, Albenberg L, et al. Gut microbiota and IBD: causation or correlation? Nat Rev Gastroenterol Hepatol. 2017;14(10):573–584.
  • Vogtmann E, Hua X, Zeller G, et al. Colorectal cancer and the human gut microbiome: reproducibility with whole genome shotgun sequencing. PLoS One. 2016;11(5):e0155362.
  • Smillie CS, Sauk J, Gevers D, et al. Strain tracking reveals the determinants of bacterial engraftment in the human gut following fecal microbiota transplantation. Cell Host Microbe. 2018;23(2):229–240.
  • Vermeire S, Joossens M, Verbeke K, et al. Donor species richness determines faecal microbiota transplantation success in inflammatory bowel disease. ECCOJC. 2016;10(4):387–394.
  • Cohen LJ, Cho JH, Gevers D, et al. Genetic factors and the intestinal microbiome guide development of microbe-based therapies for inflammatory bowel diseases. Gastroenterology. 2019;156(8):2174–2189.
  • Ranjan R, Rani A, Metwally A, et al. Analysis of the microbiome: advantages of whole genome shotgun versus 16S amplicon sequencing. Biochem Biophys Res Commun. 2016;469(4):967–977.
  • Callahan B, McMurdie P, Holmes S. Exact sequence variants should replace operational taxonomic units in marker-gene data analysis. ISME J. 2017;11(12):2639–2643.
  • Dueholm MS, Andersen KS, Petriglieri F, et al. Comprehensive ecosystem-specific 16S rRNA gene databases with automated taxonomy assignment (AutoTax) provide species-level resolution in microbial ecology. bioRxiv. 2019. DOI:10.1101/672873
  • Johnson JS, Spakowicz DJ, Hong BY, et al. Evaluation of 16S rRNA gene sequencing for species and strain-level microbiome analysis. Nat Commun. 2019;10(1):1–11.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.