178
Views
11
CrossRef citations to date
0
Altmetric
Original Article

True Chromogranin A concentrations in plasma from patients with small intestinal neuroendocrine tumours

, , , &
Pages 565-573 | Received 20 Mar 2020, Accepted 18 Apr 2020, Published online: 30 Apr 2020

References

  • Jensen TB, Hilsted L, Rehfeld JF. Library of sequence-specific radioimmunoassays for human Chromogranin A. Clin Chem. 1999;45(4):549–560.
  • Feldman SA, Eiden LE. The chromogranins: their roles in secretion from neuroendocrine cells and as markers for neuroendocrine neoplasia. Endocrine Pathol. 2003;14(1):3–23.
  • Stridsberg M, Eriksson B, Öberg, K, et al. A panel of 11 region-specific radioimmunoassays for measurements of human Chromogranin A. Regul Pept. 2004;117(3):219–227.
  • Öberg K, Knigge U, Kwekkeboom D, et al. Neuroendocrine gastro-entero-pancreatic tumors: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2012;23:vii124–130.
  • Bech PR, Martin NM, Ramachandran R, et al. The biochemical utility of Chromogranin A, Chromogranin B and cocaine- and amphetamine-regulated transcript for neuroendocrine neoplasia. Ann Clin Biochem. 2014;51(1):8–21.
  • Tiensuu Janson E, Sorbye H, Welin S, et al. Nordic Guidelines 2014 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms. Acta Oncol. 2014;53(10):1284–1297.
  • Öberg K, Modlin IM, de Herder W, et al. Consensus on biomarkers for neuroendocrine tumour disease. Lancet Oncol. 2015;16(9):e435–e446.
  • Niederle B, Pape UF, Costa F, et al. ENETS consensus guidelines update for neuroendocrine neoplasms of the jejunum and ileum. Neuroendocrinology. 2016;103(2):125–138.
  • Hofland J, Zandee WT, de Herder WW. Role of biomarker tests for diagnosis of neuroendocrine tumours. Nat Rev Endocrinol. 2018;14(11):656–669.
  • Taupenot L, Harper KL, O'Connor DT. The chromogranin-secretogranin family. N Engl J Med. 2003;348(12):1134–1149.
  • Helle KB. Chromogranins A and B and secretogranin II as prohormones for regulatory peptides from the diffuse neuroendocrine system. Results Probl Cell Differ. 2010;50:21–44.
  • Rehfeld JF, Goetze JP. The posttranslational phase of gene expression: new possibilities in molecular diagnosis. CMM. 2003;3(1):25–38.
  • Børglum T, Rehfeld JF, Drivsholm LB, et al. Processing-independent quantitation of Chromogranin A in plasma from patients with neuroendocrine tumors and small-cell lung carcinomas. Clin Chem. 2007;53(3):438–446.
  • Karush F. Immunological specificity and molecular structure. Adv Immunol. 1962;2:1–40.
  • Schechter I. Mapping of the combining sites of antibodies specific for poly-L-alanine determinants. Nature. 1970;228(5272):639–641.
  • Bardram L, Rehfeld JF. Processing-independent radioimmunoanalysis: a general analytical principle applied to progastrin and its products. Anal Biochem. 1988;175(2):537–543.
  • Konecki DS, Benedum UM, Gerdes HH, et al. The primary structure of human Chromogranin A and pancreastatin. J Biol Chem. 1987;262(35):17026–17030.
  • Klimstra DS, Klöppel G, La Rosa S, et al. 2019. Classification of neuroendocrine neoplasms of the digestive system. In: WHO classification of tumors, digestive system tumours, 5th edn. Lyon: WHO Press, IARC; pp 16–19.
  • DeLong ER, DeLong DM, Clarke-Pearson D. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics. 1988;44(3):837–845.
  • Robin X, Turck N, Hainard A, et al. pROC: An open source package for R and S + to analyze and compare ROC curves. BMC Bioinf. 2011;12(1):77.
  • Lopez-Raton M, Rodriguez-Alvarez MX, Suarez CC, et al. Optimal cutpoints: an R package for selecting optimal cut points in diagnostic tests. J Stat Soft. 2014;61(8):1–36.
  • Ludbrook J. Linear regression analysis for comparing two measurers or methods of measurement: but which regression?. Clin Exp Pharmacol Physiol. 2010;37(7):692–699.
  • Klöppel G, Anlauf M. Epidemiology, tumour biology and histopathological classification of neuroendocrine tumours of the gastrointestinal tract. Best Practice Res. 2005;19(4):507–517.
  • Modlin IM, Öberg K, Chung DC, et al. Gastroenteropancreatic neuroendocrine tumours. Lancet Oncol. 2008;9(1):61–72.
  • Yao JC, Hassan M, Phan A, et al. One hundred years after ‘carcinoid’: epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States. JCO. 2008;26(18):3063–3072.
  • Niederle MB, Hackl M, Kaserer K, et al. Gastroenteropancreatic neuroendocrine tumours: the current incidence and staging based on the WHO and European Neuroendocrine Tumour Society classification: an analysis based on prospectively collected parameters. Endocrine-Relat Cancer. 2010;17(4):909–918.
  • Lawrence B, Gustafsson BI, Chan A, et al. The epidemiology of gastroenteropancreatic neuroendocrine tumors. Endocrinol Metab Clin North America. 2011;40(1):1–18.
  • Rehfeld JF, Gingras MH, Bardram L, et al. Zollinger-Ellison syndrome and mismeasurement of gastrin. Gastroenterology. 2011;140(5):1444–1453.
  • Hansen LH, Darkner S, Svendsen JH, et al. Chromogranin A in the mammalian heart: expression without secretion. Biomarkers Med. 2017;11(7):541–545.
  • Saenger AK, Rodriguez-Fraga O, Ler R, et al. Specificity of B-type natriuretic peptide assays: cross-reactivity with different BNP, NT-proBNP, and proBNP Peptides. Clin Chem. 2017;63(1):351–358.
  • Madsen OD, Karlsen C, Nielsen E, et al. The dissociation of tumor-induced weight loss from hypoglycemia in a transplantable pluripotent rat islet cell tumor results in the segregation of stable alpha- and beta-cell tumor phenotypes. Endocrinology. 1993;133(5):2022–2030.
  • Rehfeld JF, Federspiel B, Agersnap M, et al. The uncovering and characterization of a CCKoma syndrome in enteropancreatic neuroendocrine tumour patients. Scand J Gastroenterol. 2016;51(10):1172–1178.
  • Modlin IM, Aslanian H, Bodei L, et al. A PCR blood test outperforms Chromogranin A in carcinoid detection and is unaffected by proton pump inhibitors. Endocrine Connect. 2014;3(4):215–223.
  • Öberg K, Krenning E, Sundin A, et al. A Delphic consensus assessment: imaging and biomarkers in gastroenteropancreatic neuroendocrine tumor disease management. Endocrine Connect. 2016;5(5):174–187.
  • Kidd M, Bodei L, Modlin IM. Chromogranin A: any relevance in neuroendocrine tumors? Curr Opin Endocrinol Diab Obesity. 2016;23(1):28–37.
  • Malczewska A, Kidd M, Matar S, et al. An assessment of circulating Chromogranin A as a biomarker of bronchopulmonary neuroendocrine neoplasma: a systematic review and meta-analysis. Neuroencrinology. 2020;110(3–4):198–216.
  • Malczewska A, Kos-Kudla B, Kidd M, et al. The clinical applications of a multigene liquid biopsy (NETest) in neuroendocrine tumors. Adv Med Sci. 2020;65(1):18–29.
  • Rehfeld JF, Bardram L, Hilsted L, et al. An evaluation of Chromogranin A versus gastrin and progastrin in gastrinoma diagnosis and control. Biomarkers Med. 2014;8(4):571–580.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.