Visceral fat area to appendicular muscle mass ratio as a predictor for nonalcoholic fatty liver disease independent of obesity

References

• Younossi ZM, Koenig AB, Abdelatif D, et al. Global epidemiology of nonalcoholic fatty liver disease-meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology. 2016;64:73–84.
   PubMed Web of Science ®Google Scholar
• Jin YJ, Kim KM, Hwang S, et al. Exercise and diet modification in non-obese non-alcoholic fatty liver disease: analysis of biopsies of living liver donors. J Gastroenterol Hepatol. 2012;27:1341–1347.
   PubMed Web of Science ®Google Scholar
• Younossi ZM. Non-alcoholic fatty liver disease – a global public health perspective. J Hepatol. 2019;70:531–544.
   PubMed Web of Science ®Google Scholar
• Targher G, Byrne CD, Lonardo A, et al. Non-alcoholic fatty liver disease and risk of incident cardiovascular disease: a meta-analysis. J Hepatol. 2016;65:589–600.
   PubMed Web of Science ®Google Scholar
• Ampuero J, Aller R, Gallego-Durán R, et al. Significant fibrosis predicts new-onset diabetes mellitus and arterial hypertension in patients with NASH. J Hepatol. 2020;73:17–25.
   PubMed Web of Science ®Google Scholar
• Koo BK, Kim D, Joo SK, et al. Sarcopenia is an independent risk factor for non-alcoholic steatohepatitis and significant fibrosis. J Hepatol. 2017;66:123–131.
   PubMed Web of Science ®Google Scholar
• Gan D, Wang L, Jia M, et al. Low muscle mass and low muscle strength associate with nonalcoholic fatty liver disease. Clin Nutr. 2020;39:1124–1130.
   PubMed Web of Science ®Google Scholar
• Petersen MC, Shulman GI. Mechanisms of insulin action and insulin resistance. Physiol Rev. 2018;98:2133–2223.
   PubMed Web of Science ®Google Scholar
• Lonardo A, Mantovani A, Lugari S, et al. Epidemiology and pathophysiology of the association between NAFLD and metabolically healthy or metabolically unhealthy obesity. Ann Hepatol. 2020;19:359–366.
   PubMed Web of Science ®Google Scholar
• Shah RV, Murthy VL, Abbasi SA, Blankstein R, et al. Visceral adiposity and the risk of metabolic syndrome across body mass index: the MESA Study. JACC Cardiovasc Imaging. 2014;7:1221–1235.
   PubMed Web of Science ®Google Scholar
• Lim S, Kim JH, Yoon JW, et al. Sarcopenic obesity: prevalence and association with metabolic syndrome in the Korean Longitudinal Study on Health and Aging (KLoSHA). Diabetes Care. 2010;33:1652–1654.
   PubMed Web of Science ®Google Scholar
• Palmer BF, Clegg DJ. The sexual dimorphism of obesity. Mol Cell Endocrinol. 2015;402:113–119.
   PubMed Web of Science ®Google Scholar
• Kitamura I, Koda M, Otsuka R, et al. Six-year longitudinal changes in body composition of middle-aged and elderly Japanese: age and sex differences in appendicular skeletal muscle mass. Geriatr Gerontol Int. 2014;14:354–361.
   PubMed Web of Science ®Google Scholar
• Lonardo A, Suzuki A. Sexual dimorphism of NAFLD in adults. Focus on clinical aspects and implications for practice and translational research. JCM. 2020;9:1278.
   Web of Science ®Google Scholar
• Wong VW, Chan WK, Chitturi S, et al. Asia-Pacific Working Party on Non-alcoholic Fatty Liver Disease guidelines 2017-Part 1: Definition, risk factors and assessment. J Gastroenterol Hepatol. 2018;33:70–85.
   PubMed Web of Science ®Google Scholar
• Peng TC, Wu LW, Chen WL, et al. Nonalcoholic fatty liver disease and sarcopenia in a Western population (NHANES III): the importance of sarcopenia definition. Clin Nutr. 2019;38:422–428.
   PubMed Web of Science ®Google Scholar
• Jia W, Weng J, Zhu D, Chinese Diabetes Society, et al. Standards of medical care for type 2 diabetes in China 2019. Diabetes Metab Res Rev. 2019;35:e3158.
   PubMed Web of Science ®Google Scholar
• Zuo L, Ma YC, Zhou YH, et al. Application of GFR-estimating equations in Chinese patients with chronic kidney disease. Am J Kidney Dis. 2005;45:463–472.
   PubMed Web of Science ®Google Scholar
• 2016 Chinese guidelines for the management of dyslipidemia in adults. J Geriatr Cardiol. 2018;15:1–29.
   PubMedGoogle Scholar
• Kim D, Kim WR. Nonobese fatty liver disease. Clin Gastroenterol Hepatol. 2017;15:474–485.
   PubMed Web of Science ®Google Scholar
• Shea JL, King MT, Yi Y, et al. Body fat percentage is associated with cardiometabolic dysregulation in BMI-defined normal weight subjects. Nutr Metab Cardiovasc Dis. 2012;22:741–747.
   PubMed Web of Science ®Google Scholar
• Kim D, Chung GE, Kwak MS, et al. Body fat distribution and risk of incident and regressed nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. 2016;14:132–138.e134.
   PubMed Web of Science ®Google Scholar
• Ramirez-Velez R, Correa-Bautista JE, Sanders-Tordecilla A, et al. Percentage of body fat and fat mass index as a screening tool for metabolic syndrome prediction in Colombian University Students. Nutrients. 2017;9:1009.
   PubMed Web of Science ®Google Scholar
• Kim BJ, Ahn SH, Lee SH, et al. Lower hand grip strength in older adults with non-alcoholic fatty liver disease: a nationwide population-based study. Aging (Albany NY). 2019;11:4547–4560.
   PubMedGoogle Scholar
• Distefano G, Goodpaster BH. Effects of exercise and aging on skeletal muscle. Cold Spring Harb Perspect Med. 2018;8:a029785.
   PubMed Web of Science ®Google Scholar
• Wilkinson DJ, Piasecki M, Atherton PJ. The age-related loss of skeletal muscle mass and function: measurement and physiology of muscle fibre atrophy and muscle fibre loss in humans. Ageing Res Rev. 2018;47:123–132.
   PubMed Web of Science ®Google Scholar
• Tchernof A, Després JP. Pathophysiology of human visceral obesity: an update. Physiol Rev. 2013;93:359–404.
   PubMed Web of Science ®Google Scholar
• Prentice AM, Jebb SA. Beyond body mass index. Obes Rev. 2001;2:141–147.
   PubMedGoogle Scholar
• Shida T, Akiyama K, Oh S, et al. Skeletal muscle mass to visceral fat area ratio is an important determinant affecting hepatic conditions of non-alcoholic fatty liver disease. J Gastroenterol. 2018;53:535–547.
   PubMed Web of Science ®Google Scholar
• Osaka T, Hashimoto Y, Okamura T, et al. Reduction of fat to muscle mass ratio is associated with improvement of liver stiffness in diabetic patients with non-alcoholic fatty liver disease. JCM. 2019;8:2175.
   Web of Science ®Google Scholar
• Kurt Z, Barrere-Cain R, LaGuardia J, et al. Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease. Biol Sex Differ. 2018;9:46.
   PubMed Web of Science ®Google Scholar
• Maltais ML, Desroches J, Dionne IJ. Changes in muscle mass and strength after menopause. J Musculoskelet Neuronal Interact. 2009;9:186–197.
   PubMed Web of Science ®Google Scholar
• Meoli L, Isensee J, Zazzu V, et al. Sex- and age-dependent effects of Gpr30 genetic deletion on the metabolic and cardiovascular profiles of diet-induced obese mice. Gene. 2014;540:210–216.
   PubMed Web of Science ®Google Scholar
• Shi Y, Wang Q, Sun Y, et al. The prevalence of lean/nonobese nonalcoholic fatty liver disease: a systematic review and meta-analysis. J Clin Gastroenterol. 2020;54:378–387.
   PubMed Web of Science ®Google Scholar
• Dong J, Dong Y, Dong Y, et al. Inhibition of myostatin in mice improves insulin sensitivity via irisin-mediated cross talk between muscle and adipose tissues. Int J Obes (Lond). 2016;40:434–442.
   PubMed Web of Science ®Google Scholar
• Wajchenberg BL. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr Rev. 2000;21:697–738.
   PubMed Web of Science ®Google Scholar
• Nielsen S, Guo Z, Johnson CM, et al. Splanchnic lipolysis in human obesity. J Clin Invest. 2004;113:1582–1588.
   PubMed Web of Science ®Google Scholar
• Tilg H, Moschen AR. Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis. Hepatology. 2010;52:1836–1846.
   PubMed Web of Science ®Google Scholar
• Polyzos SA, Toulis KA, Goulis DG, et al. Serum total adiponectin in nonalcoholic fatty liver disease: a systematic review and meta-analysis. Metabolism. 2011;60:313–326.
   PubMed Web of Science ®Google Scholar
• Fukuda Y, Hashimoto Y, Hamaguchi M, et al. Triglycerides to high-density lipoprotein cholesterol ratio is an independent predictor of incident fatty liver; a population-based cohort study. Liver Int. 2016;36:713–720.
   PubMed Web of Science ®Google Scholar
• Lonardo A, Nascimbeni F, Ballestri S, et al. Sex differences in nonalcoholic fatty liver disease: state of the art and identification of research gaps. Hepatology. 2019;70:1457–1469.
   PubMed Web of Science ®Google Scholar