Methylation profile of colon cancer genes in colorectal precursor lesions and tumor tissue: perspectives for screening

References

• Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424.
   PubMed Web of Science ®Google Scholar
• (INCA) INdCJAGdS. Estimativa 2020/Incidência de Câncer no Brasil https://www.inca.gov.br/estimativa.
   Google Scholar
• Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 1990;61(5):759–767.
   PubMed Web of Science ®Google Scholar
• Yamane L, Scapulatempo-Neto C, Reis RM, et al. Serrated pathway in colorectal carcinogenesis. World J Gastroenterol. 2014;20(10):2634–2640.
   PubMed Web of Science ®Google Scholar
• WHO Classification of Tumour. Digestive system tumours. 5th ed. Lyon: International Agency for Research on Cancer; 2019.
   Google Scholar
• Lao VV, Grady WM. Epigenetics and colorectal cancer. Nat Rev Gastroenterol Hepatol. 2011;8(12):686–700.
   PubMed Web of Science ®Google Scholar
• Kim YH, Petko Z, Dzieciatkowski S, et al. CpG island methylation of genes accumulates during the adenoma progression step of the multistep pathogenesis of colorectal cancer. Genes Chromosomes Cancer. 2006;45(8):781–789.
   PubMed Web of Science ®Google Scholar
• Ebert MP, Model F, Mooney S, et al. Aristaless-like homeobox-4 gene methylation is a potential marker for colorectal adenocarcinomas. Gastroenterology. 2006;131(5):1418–1430.
   PubMed Web of Science ®Google Scholar
• Lofton-Day C, Model F, Devos T, et al. DNA methylation biomarkers for blood-based colorectal cancer screening. Clin Chem. 2008;54(2):414–423.
   PubMed Web of Science ®Google Scholar
• Song L, Jia J, Peng X, et al. The performance of the SEPT9 gene methylation assay and a comparison with other CRC screening tests: a meta-analysis. Sci Rep. 2017;7(1):3032.
   PubMed Web of Science ®Google Scholar
• Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med. 2014;370(14):1287–1297.
   PubMed Web of Science ®Google Scholar
• Guimaraes DP, Fregnani JH, Reis RM, et al. Comparison of a new-generation fecal immunochemical test (FIT) with Guaiac fecal occult blood test (gFOBT) in detecting colorectal neoplasia among colonoscopy-referral patients. Anticancer Res. 2019;39(1):261–269.
   PubMed Web of Science ®Google Scholar
• Edge SB, Compton CC. The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. Ann Surg Oncol. 2010;17(6):1471–1474.
   PubMed Web of Science ®Google Scholar
• Berardinelli GN, Scapulatempo-Neto C, Duraes R, et al. Advantage of HSP110 (T17) marker inclusion for microsatellite instability (MSI) detection in colorectal cancer patients. Oncotarget. 2018;9(47):28691–28701.
   PubMedGoogle Scholar
• Yamane LS, Scapulatempo-Neto C, Alvarenga L, et al. KRAS and BRAF mutations and MSI status in precursor lesions of colorectal cancer detected by colonoscopy. Oncol Rep. 2014;32(4):1419–1426.
   PubMed Web of Science ®Google Scholar
• Perez-Carbonell L, Balaguer F, Toiyama Y, et al. IGFBP3 methylation is a novel diagnostic and predictive biomarker in colorectal cancer. PLoS One. 2014;9(8):e104285.
   PubMed Web of Science ®Google Scholar
• Shaw RJ, Liloglou T, Rogers SN, et al. Promoter methylation of P16, RARbeta, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing. Br J Cancer. 2006;94(4):561–568.
   PubMed Web of Science ®Google Scholar
• Tost J, Gut IG. DNA methylation analysis by pyrosequencing. Nat Protoc. 2007;2(9):2265–2275.
   PubMed Web of Science ®Google Scholar
• Newton K, Jorgensen NM, Wallace AJ, et al. Tumour MLH1 promoter region methylation testing is an effective prescreen for Lynch Syndrome (HNPCC). J Med Genet. 2014;51(12):789–796.
   PubMed Web of Science ®Google Scholar
• Dantas RB, Oliveira GL, Silveira AM. Psychometric properties of the vulnerability to abuse screening scale for screening abuse of older adults. Rev Saude Publica. 2017;51:31.
   PubMed Web of Science ®Google Scholar
• Payne SR. From discovery to the clinic: the novel DNA methylation biomarker (m)SEPT9 for the detection of colorectal cancer in blood. Epigenomics. 2010;2(4):575–585.
   PubMed Web of Science ®Google Scholar
• deVos T, Tetzner R, Model F, et al. Circulating methylated SEPT9 DNA in plasma is a biomarker for colorectal cancer. Clin Chem. 2009;55(7):1337–1346.
   PubMed Web of Science ®Google Scholar
• Church TR, Wandell M, Lofton-Day C, PRESEPT Clinical Study Steering Committee, Investigators and Study Team, et al. Prospective evaluation of methylated SEPT9 in plasma for detection of asymptomatic colorectal cancer. Gut. 2014;63(2):317–325.
   PubMed Web of Science ®Google Scholar
• Behrouz Sharif S, Hashemzadeh S, Mousavi Ardehaie R, et al. Detection of aberrant methylated SEPT9 and NTRK3 genes in sporadic colorectal cancer patients as a potential diagnostic biomarker. Oncol Lett. 2016;12(6):5335–5343.
   PubMed Web of Science ®Google Scholar
• Toth K, Wasserkort R, Sipos F, et al. Detection of methylated septin 9 in tissue and plasma of colorectal patients with neoplasia and the relationship to the amount of circulating cell-free DNA. PLoS One. 2014;9(12):e115415.
   PubMed Web of Science ®Google Scholar
• Semaan A, van Ellen A, Meller S, et al. SEPT9 and SHOX2 DNA methylation status and its utility in the diagnosis of colonic adenomas and colorectal adenocarcinomas. Clin Epigenet. 2016;8(1):100.
   PubMed Web of Science ®Google Scholar
• He Q, Chen HY, Bai EQ, et al. Development of a multiplex methylight assay for the detection of multigene methylation in human colorectal cancer. Cancer Genet Cytogenet. 2010;202(1):1–10.
   PubMedGoogle Scholar
• Tanzer M, Balluff B, Distler J, et al. Performance of epigenetic markers SEPT9 and ALX4 in plasma for detection of colorectal precancerous lesions. PLoS One. 2010;5(2):e9061.
   PubMed Web of Science ®Google Scholar
• Houshmand M, Abbaszadegan MR, Kerachian MA. Assessment of bone morphogenetic protein 3 methylation in Iranian patients with colorectal cancer. Middle East J Dig Dis. 2017;9(3):158–163.
   PubMedGoogle Scholar
• Park SK, Song CS, Yang HJ, et al. Field cancerization in sporadic colon cancer. Gut Liver. 2016;10(5):773–780.
   PubMed Web of Science ®Google Scholar
• Zou H, Allawi H, Cao X, et al. Quantification of methylated markers with a multiplex methylation-specific technology. Clin Chem. 2012;58(2):375–383.
   PubMed Web of Science ®Google Scholar
• Liang TJ, Wang HX, Zheng YY, et al. APC hypermethylation for early diagnosis of colorectal cancer: a meta-analysis and literature review. Oncotarget. 2017;8(28):46468–46479.
   PubMedGoogle Scholar
• Sanz-Casla MT, Maestro ML, Vidaurreta M, et al. p16 Gene methylation in colorectal tumors: correlation with clinicopathological features and prognostic value. Dig Dis. 2005;23(2):151–155.
   PubMed Web of Science ®Google Scholar
• Anacleto C, Leopoldino AM, Rossi B, et al. Colorectal cancer "methylator phenotype": fact or artifact? Neoplasia. 2005;7(4):331–335.
   PubMed Web of Science ®Google Scholar
• van Roon EH, van Puijenbroek M, Middeldorp A, et al. Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition? BMC Cancer. 2010; 10:180.
   PubMed Web of Science ®Google Scholar
• Patai AV, Valcz G, Hollosi P, et al. Comprehensive DNA methylation analysis reveals a common ten-gene methylation signature in colorectal adenomas and carcinomas. PLoS One. 2015;10(8):e0133836.
   PubMed Web of Science ®Google Scholar
• Toyota M, Ahuja N, Ohe-Toyota M, et al. CpG island methylator phenotype in colorectal cancer. Proc Natl Acad Sci USA. 1999;96(15):8681–8686.
   PubMed Web of Science ®Google Scholar
• Weisenberger DJ, Siegmund KD, Campan M, et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet. 2006;38(7):787–793.
   PubMed Web of Science ®Google Scholar
• Park SJ, Rashid A, Lee JH, et al. Frequent CpG island methylation in serrated adenomas of the colorectum. Am J Pathol. 2003;162(3):815–822.
   PubMed Web of Science ®Google Scholar
• Zou H, Harrington JJ, Shire AM, et al. Highly methylated genes in colorectal neoplasia: implications for screening. Cancer Epidemiol Biomarkers Prev. 2007;16(12):2686–2696.
   PubMed Web of Science ®Google Scholar
• Leong KJ, Wei W, Tannahill LA, et al. Methylation profiling of rectal cancer identifies novel markers of early-stage disease. Br J Surg. 2011;98(5):724–734.
   PubMed Web of Science ®Google Scholar