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Scandinavian Journal of Gastroenterology Volume 58, 2023 - Issue 3
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Original Articles

High real-world effectiveness of 12-week elbasvir/grazoprevir without resistance testing in the treatment of patients with HCV genotype 1a infection in Norway

Rafael A. Leivaa Department of Infectious Diseases, Haukeland University Hospital, Bergen, NorwayCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-4750-5861
ORCID Icon,
Bente M. Bergersenb Department of Infectious Diseases, Oslo University Hospital, Ullevål, Norway
,
Ane-Kristine Finbråtenb Department of Infectious Diseases, Oslo University Hospital, Ullevål, Norway;c Unger-Vetlesen Institute, Lovisenberg Diaconal Hospital, Oslo, Norway
,
Per Kristian Sandveid Department of Infectious Diseases, Østfold Hospital, Kalnes, Norway
,
Øystein Simonsend Department of Infectious Diseases, Østfold Hospital, Kalnes, Norway
,
Carola M. Rosselande MSD AS, Drammen, Norway
,
Karin Hagenf MSD AB, Stockholm, Sweden
,
Lital Youngg MSD AG, Luzern, Switzerland
,
R. Scott Robertsh LINK Medical AS, Oslo, Norway
,
Yngve Mikkelsenh LINK Medical AS, Oslo, Norway
,
Ravinder Singhe MSD AS, Drammen, Norway
,
Martin Laggingi Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden;j Department of Clinical Microbiology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, SwedenORCID Iconhttps://orcid.org/0000-0002-7995-3626
ORCID Icon &
Olav Dalgardk Department of Infectious Diseases, Akershus University Hospital, Lørenskog, Norway;l Institute for Clinical Medicine, University of Oslo, Oslo, Norway
 show all
Pages 264-268 | Received 30 Apr 2022, Accepted 23 Aug 2022, Published online: 05 Sep 2022

References

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  • Zeuzem S, Ghalib R, Reddy KR, et al. Grazoprevir–elbasvir combination therapy for treatment-naive cirrhotic and noncirrhotic patients with chronic hepatitis C virus genotype 1, 4, or 6 infection. A randomized trial C-EDGE treatment naive trial of grazoprevir–elbasvir. Ann Intern Med. 2015;163(1):1–13. https://doi.org/10.7326/M15-0785.
  • Jacobson IM, Asante-Appiah E, Wong P, et al. Prevalence and impact of baseline NS5A resistance-associated variants (RAVs) on the efficacy of elbasvir/grazoprevir (EBR/GZR) against GT1a infection – 16 weeks vs 12 weeks. 66th Annual Meeting of the American Association for the Study of Liver Diseases. Boston, MA 2015. https://www.natap.org/2015/AASLD/AASLD_47.htm
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  • Toresen KH, Salte IM, Skrede S, et al. Clinical outcomes in a cohort of anti-hepatitis C virus-positive patients with significant barriers to treatment referred to a Norwegian outpatient clinic. Scand J Gastroenterol. 2014;49(4):465–472. https://doi.org/10.3109/00365521.2013.863965.
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