REFERENCES
- Weiss SJ. Tissue destruction by neutrophils. N Engl J Med 1989;320:365–76.
- Weidinger S, Cleve H, Patutschnick W. Alpha1-antitrypsin: evidence for a fourth PiM allele. Distribution of the PiM subtypes in Southern Germany. Z Rechtsmed 1982;88: 203–11.
- Silverman EK, Province MA, Rao DC, Pierce JA, Campbell EJ. A family study of the variability of pulmonary function in alpha 1-antitrypsin deficiency. Quantitative phenotypes. Am Rev Respir Dis 1990;142: 1015–21.
- Silverman EK, Pierce JA, Province MA, Rao DC, Campbell EJ. Variability of pulmonary function in alpha-1-antitrypsin deficiency: clinical correlates. Ann Intern Med 1989;111: 982–91.
- Silverman EK, Miletich JP, Pierce JA. Alpha-1-antitrypsin deficiency. High prevalence in the St. Louis area determined by direct population screening. Am Rev Respir Dis 1989;40: 961–6.
- Silverman EK, Province MA, Campbell EJ, Pierce JA, Rao DC. Variability of pulmonary function in alpha-1-antitrypsin deficiency: residual family resemblance beyond the effect of the Pi locus. Hum Hered 1990;40: 340–55.
- Silverman EK, Province MA, Campbell EJ, Pierce JA, Rao DC. Biochemical intermediates in alpha 1-antitrypsin deficiency: residual family resemblance for total alpha 1-antitrypsin, oxidized alpha 1-antitrypsin, and immunoglobulin E after adjustment for the effect of the Pi locus. Genet Epidemiol 1990;7: 137–49.
- Teckman JH, Perlmutter DH. The endoplasmic reticulum degradation pathway for mutant secretory proteins alpha1- antitrypsin Z and S is distinct from that for an unassembled membrane protein. J Biol Chem 1996;271:13215–20.
- Zegers ND, Claassen E, Gerritse K, Deen C, Boersma WJ. Detection of genetic variants of alpha 1-antitrypsin with site- specific monoclonal antibodies. Clin Chem 1991;37: 1606–11.
- Van Steenbergen W. Alpha-1-antitrypsin deficiency: an overview. Acta Clin Belg 1993;27:171–89.
- Stallmach A, Schuppan D, Riese HH, Matthes H, Riecken EO. Increased collagen type III synthesis by fibroblasts isolated from strictures of patients with Crohn’s disease. Gastroenterology 1992;102:1920–9.
- Stallmach A, von Lampe B, Matthes H, Bornhoft G, Riecken EO. Diminished expression of integrin adhesion molecules on human colonic epithelial cells during the benign to malign tumour transformation. Gut 1992;33:342–6.
- Matthes H, Stallmach A, Matthes B, Herbst H, Schuppan D, Riecken EO. Indications for different collagen metabolism in Crohn disease and ulcerative colitis. Med Klin 1993;88:185–92.
- O’Morain C, Smethurst P, Levi AJ, Peters TJ. Biochemical analysis of enzymic markers of inflammation in rectal biopsies from patiens with ulcerative colitis and Crohn’s disease. J Clin Pathol 1983;36:1312–6.
- Kane SP, Vincenti AC. Mucosal enzymes in human inflammatory bowel disease with reference to neutrophil granulocytes as mediators o tissue injury. Clin Sci 1979;57:295–303.
- Adeyemi EO, Neumann S, Chadwick VS, Hodgson HJ, Pepys MB. Circulating human leucocyte elastase in patients with inflammatory bowel disease. Gut 1985;26:1306–11.
- Falchuk KR, Perotto JL, Isselbacher KJ. Serum lysozyme in Crohn’s disease. A useful index of disease activity. Gastroenterology 1975;69:893–6.
- Dronfield MW, Langman MJS. Serum lysozyme in inflammatory bowel disease. Gut 1975;16:985–7.
- Klaas HJ, Naele G. Serum and fecal lysozyme in inflammatory bowel disease. Gut 1978;19:233–9.
- Mallas E, Terry JM, Asquith P, Cooke WT. Serum lysozyme in inflammatory bowel disease and coeliac disease. J Clin Pathol 1976;29:598–600.
- Bailey CJ, Hembry RM, Alexander A, Irving MH, Grant ME, Shuttleworth CA. Distribution of the matrix metalloproteinases stromelysin, gelatinases A and B, and collagenase in Crohn’s disease and normal intestine. J Clin Pathol 1994;47:113–6.
- Tsai HH, Dwarakanath AD, Hart CA, Milton JD, Rhodes JM. Increased faecal mucin sulphatase activity in ulcerative colitis: a potential target for treatment. Gut 1995;36:570–6.
- Weidinger S, Jahn W, Cujnik F, Schwarzfischer F. Alpha-1- antitrypsin: evidence for a fifth PI M subtype and a new deficiency allele PI*Z augsburg. Hum Genet 1985;71:27–9.
- Sires UI, Murphy G, Baragi VM, Fliszar CJ, Welgus HG, Senior RM. Matrilysin is much more efficient than other matrix metalloproteinases in the proteolytic inactivation of alpha 1- antitrypsin. Biochem Biophys Res Commun 1994;204:613–20.
- Segelmark M, Elzouki AN, Wieslander J, Eriksson S. The PiZ gene of alpha 1-antitrypsin as a determinant of outcome in PR3- ANCA-positive vasculitis. Kidney Int 1995;48:844–50.
- Podolsky DK. Inflammatory bowel disease. II. N Engl J Med 1991;325:1008–16.