Low Symptomatic Load in Crohn's Disease with Surgery and Medicine as Complementary Treatments

REFERENCES

• Kirsner JB. The local and systemic complications of inflammatory bowel disease. JAMA 1979;242:1177–83.
   PubMedGoogle Scholar
• Tytgat GNJ, Mulder CJJ, Brummelkamp WH. Endoscopic lesions in Crohn's disease early after ileocecal resection. Endoscopy 1988;20:260–2.
   Google Scholar
• Rutgeers P, Geboes K, Vantrappen G, Kerremans R, Coenegrachts JL, Coremans G. Natural history of recurrent Crohn’s disease at the ileocolonic anastomoses after curative surgery. Gut 1984;25:665–72.
   PubMedGoogle Scholar
• Olaison G, Smedh K, Sjödahl R. Natural course of Crohn’s disease after ileocolic resection—early endoscopic ileal ulcers preceding symptoms. Gut 1992;33:331–3.
   Google Scholar
• Rutgeerts P, Geboes K, Vantrappen G, Beyls J, Kerremans R, Hiele M. Predictability of the postoperative course of Crohn’s disease. Gastroenterology 1990;99:956–62.
   PubMed Web of Science ®Google Scholar
• Smedh K, Olaison G, Sjödahl R. Initiation of anastomotic recurrence of Crohn’s disease after ileocolic resection. Onset proximal to the junction and preceded by a raised phospholipase A2 activity. Scand J Gastroenterol 1992;27: 691–4.
   Google Scholar
• Malchow H, Ewe K, Brandes JW, Goebell H, Ehms H, Sommer H, et al. European Cooperative Crohn’s Disease Study (ECCDS): results of drug treatment. Gastroenterology 1984;86:249–66.
   PubMed Web of Science ®Google Scholar
• Bello C, Goldstein F, Thornton JJ. Alternate-day prednisone treatment and treatment maintenance in Crohn’s disease. Am J Gastrenterol 1991;86:460–6.
   Google Scholar
• Löfberg R, Rutgeerts P, Malchow H, Lamers C, Danielsson Å, Olaison G, et al. Budesonide prolongs time to relapse in ileal and ileocecal Crohn’s disease. Gut 1996;39:82–6.
   Google Scholar
• Thomson ABR, International Mezasalasine Study Group. Coated oral 5-aminosalicylic acid versus placebo in maintaining remission of inactive Crohn’s disease. Aliment Pharmacol Ther 1990;4:55–64.
   PubMedGoogle Scholar
• Prantera C, Francesco P, Brunetti G, Cottone M, Miglioli M. Oral 5-aminosalicylic acid (Asacol) in the maintenance treatment of Crohn’s disease. Gastroenterology 1992;103: 363–8.
   Google Scholar
• Gendre JP, Mary JY, Florent C, Modigliani R, Colombel JF, Soule JC, et al. Oral mesalamine as maintenance treatment in Crohn’s disease: a multicenter placebo controlled study. Gastroenterology 1993;104:435–9.
   PubMed Web of Science ®Google Scholar
• Caprilli R, Andreoli A, Capurso L, Corrao G, Dalbasio G, Gioieno A, et al. Oral mesalazine (5-aminosalicylic acid;Asacol) for the prevention of of postoperative recurrence of Crohn’s disease. Aliment Pharmacol Ther 1994;8:35.
   PubMed Web of Science ®Google Scholar
• Messori A, Brignola C, Trallor G, Rampazzo R, Bardazzi G, Belloli C, et al. Effectiveness of 5-aminosalicylic acid for maintaining remission in patients with Crohn’s disease: a metaanalysis. Am J Gastroenterol 1994;89:6928.
   Google Scholar
• Brignola C, Cottone M, Pera A, Ardizzone S, Scribano ML, De Franchis R, et al. Mesalamine in the prevention of endoscopic recurrence after intestinal resection for Crohn’s disease. Gastroenterology 1995;108:345–9.
   Google Scholar
• McLeod RS, Wolff BG, Steinhart AH, Carryer PW, O’Rourke K, Andrews DF, et al. Prophylactic mesalamine treatment decreases postoperative recurrence of Crohn’s disease. Gastroenterology 1995;109:404–13.
   Google Scholar
• Present Dh, Korelitz BI, Wish N, Glass JL, Sachar DB, Pasternack BS. Treatment of Crohn’s disease with 6-mercaptopurine. N Engl J Med 1980;302: 981–7.
   Google Scholar
• Ewe K, Press A, Singe C, Stufler M, Uebershaer B, Hommel G, et al. Azathioprine combined with prednisolon or monotherapy with prednisolone in active Crohn’s disease. Gastroenterology 1993;105:367–72.
   PubMed Web of Science ®Google Scholar
• Bouhnik Y, Leman M, Mary JY, Scemama G, Tai R, Matuchansky C, et al. Long term follow-up of patients with Crohn’s disease treated with azathioprine or 6-mercaptopurine. Lancet 1996;1:215–9.
   Google Scholar
• Candy S, Wright JP, Gerber M, Adams G, Gerig M, Goodman R. A controlled double blind study of azathioprine in the management of Crohn’s disease. Gut 1995;37:664–8.
   Google Scholar
• Lee ECG, Papaionnou N. Minimal surgery for chronic obstruction in patients with extensive or universal Crohn’s disease. Ann Roy Coll Surg 1982;64:229–33.
   PubMed Web of Science ®Google Scholar
• Lee ECG. Aim of surgical treatment in Crohn’s disease. Gut 1984;25:217–22.
   PubMedGoogle Scholar
• Alexander-Williams J, Haynes IG. Conservative operations for Crohn’s disease of the small bowel. World J Surg 1985;9:945–51.
   Google Scholar
• Shorb PE. Surgical therapy for Crohn’s disease. Gastroenterol Clin 1989;18:111–28.
   Google Scholar
• Smedh K, Olaison G, Nyström PO, Sjödahl R. Intraoperative enteroscopy in Crohn’s disease. Br J Surg 1993;80:897–900.
   Google Scholar
• Smedh K, Olaison G, Sjödahl R. Endoscopic and exterior bowel changes and histopathology in Crohn’s disease. Br J Surg 1995; 82:191–4.
   Google Scholar
• Best WR, Becktel JM. The Crohn’s disease activity index as a clinical instrument. In: Pena A, Weterman IT, Booth CC, StroberW, editors. Recent advances in Crohn’s disease. The Hague: Martinus Nijhoff; 1981. p. 7–12.
   Google Scholar
• Armitage P, Berry G. General contingency tables. In: Statistical methods in medical research. 3rd ed. Oxford: Blackwell Science Ltd; 1994. p. 232–3.
   Google Scholar
• Lindberg E, Jarnerot G. The incidence of Crohn’s disease is not decreasing in Sweden. Scand J Gastroenterol 1991;26:495–500.
   PubMed Web of Science ®Google Scholar
• Hellers G. Crohn’s disease in Stockholm County 1955–1974: a study of epidemiology results of surgical treatment and longterm prognosis. Acta Chir Scand 1979;Suppl 490:1–83.
   Google Scholar
• Munkholm P, Langholz E, Haagen Nielsen OH, Kreiner S, Binder V. Incidence and prevalence of Crohn’s disease in the county of Copenhagen, 1962–87. A sixfold increase in incidence. Scand J Gastroenterol 1992;27: 609–14.
   Google Scholar
• Lindgren A, Wallerstedt S, Olsson R. Prevalence of Crohn’s disease and simultaneous occurence of extraintestinal complications and cancer. An epidemiologic study in adults. Scand J Gastroenterol 1996;31:74–8.
   Google Scholar
• Summers RW, Switz DM, Sessions JT Jr, Becktel JM, Best WR, Kern F Jr, et al. National Cooperative Crohn’s Disease Study: results of drug treatment. Gastroenterology 1979;77:847–69.
   Google Scholar
• Munkholm P, Langholz E, Davidsen M, Binder V. Disease activity courses in a regional cohort of Crohn’s disease patients. Scand J Gastroenterol 1995;30:699–706.
   PubMed Web of Science ®Google Scholar
• Heiman T, Greenstein A, Mecanic L, Aufses A. Early complications following surgical treatment for Crohn’s disease. Ann Surg 1984;201:494–8.
   Google Scholar
• Stokes M, Hill G. One hundred operations for Crohn’s disease. AustN Z J Surg 1990;60:677–82.
   PubMedGoogle Scholar
• Simi M, Leardi S, Minervini S, Pietroletti R, Schietroma M, Speranza V. Early complications after surgery for Crohn’s disease. Neth J Surg 1990;42–4:105–8.
   Google Scholar
• Post S, Betzler M, von Ditfurth B, Shurman G, Kuppers P, Herfarth C. Risks of intestinal anastomosis in Crohn’s disease. Ann Surg 1991;213:37–42.
   PubMed Web of Science ®Google Scholar